Biomedical Projects by Theme

Cancer in Biomedicine

Groups / Projects	Research Lead	Dept / Centre
A novel link between metabolism and host defence: O-GlcNAc glycosylation	Professor Jose Villadangos	Biochemistry and Pharmacology
Adaptive remodelling of metabolism during liver regeneration	Project Leader Dr Andrew Cox	Biochemistry and Pharmacology
Analysing genetic roles of RNA-binding proteins and alternative splicing in Drosophila stem cells	Project Leader Professor Gary Hime	Anatomy and Physiology
Analysing protein structures	Dr David Ascher	Biochemistry and Pharmacology
Andrew Cox laboratory	Head of Laboratory Dr Andrew Cox	Biochemistry and Pharmacology
Applications of Nanopore sequencing	Project Leader Dr Mike Clark	Anatomy and Physiology
Cancer in Biomedicine
Characterising the pathways responsible for ICU-acquired weakness	Research Project Leader Dr René Koopman	Anatomy and Physiology
Cheng laboratory: Stem cell and organ size control regulation	Head of Laboratory Associate Professor Louise Cheng	Anatomy and Physiology
Clinical Proteomics	Project Leader Dr Jonathon Mangum	Biochemistry and Pharmacology
Cutting off the fuel supply to starve cancer: identifying the nutrient dependencies of cancer cells	Project Leader Dr Kristin Brown	Biochemistry and Pharmacology
David Ascher laboratory	Head of Laboratory Dr David Ascher	Biochemistry and Pharmacology
Decoding the trafficking of immune receptors	A/Prof Justine Mintern	Biochemistry and Pharmacology
Defining new roles for the Hippo signalling pathway in skeletal muscle	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Designing better drugs	Dr David Ascher	Biochemistry and Pharmacology
Designing new optogenetic tools for biomedical research	A/Prof Danny Hatters	Biochemistry and Pharmacology
Developing innovative animal and cell culture models to study and treat muscular dystrophies	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Development of effector regulatory T cells	Project Leader Professor Axel Kallies	Microbiology and Immunology
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Research Project Leader Professor Matthew Watt	Anatomy and Physiology
Dolcetti Laboratory: Clinical and Translational Immunotherapy	Head of Laboratory Professor Riccardo Dolcetti	Microbiology and Immunology
Eckersley-Maslin laboratory: Stem cell and cancer epigenetics	Head of Laboratory Dr Melanie Eckersley-Maslin	Anatomy and Physiology
EMT regulators in intestinal and germline stem cells	Project Leader Professor Gary Hime	Anatomy and Physiology
Establishing the effect of glycine/serine metabolism on skeletal muscle cell growth	Research Project Leader Dr René Koopman	Anatomy and Physiology
Exploiting nanoparticles as vaccines	A/Prof Justine Mintern	Biochemistry and Pharmacology
Exploring new roles for the TGFβ signalling network as a key regulator of skeletal muscle in health and disease	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Finding clarity within a blizzard- guiding the solution of cryo-EM structures	Dr David Ascher	Biochemistry and Pharmacology
Gavin Reid laboratory	Head of Laboratory Professor Gavin E. Reid	Biochemistry and Pharmacology
Genetics of blood brain barrier formation	Project Leader Professor Ben Hogan	Anatomy and Physiology
Gregorevic laboratory: Muscle Research and Therapeutics	Head of Laboratory Associate Professor Paul Gregorevic	Anatomy and Physiology
Hime laboratory: Stem cell genetics and Drosophila models of human disease	Head of Laboratory Professor Gary Hime	Anatomy and Physiology
Hogan laboratory: Vascular Cell and Developmental Biology	Head of Laboratory Professor Ben Hogan	Anatomy and Physiology
How do dietary nutrients affect the ability of stem cells and stem cell-derived tumours to grow and divide?	Project Leader A/Professor Louise Cheng	Anatomy and Physiology
How do neural stem cells maintain quiescence?	Project Leader A/Professor Louise Cheng	Anatomy and Physiology
How do neurons maintain their specialised status?	Project Leader A/Professor Louise Cheng	Anatomy and Physiology
How do tumours compete for resources to grow?	Project Leader A/Professor Louise Cheng	Anatomy and Physiology
How infection and trauma cause dendritic cell paralysis and lethal immunosuppression	Professor Jose Villadangos	Microbiology and Immunology
How to harness the immune system to cure cancer: adoptive cell immunotherapy	Professor Jose Villadangos	Microbiology and Immunology
Immunoregulatory functions of the MARCH family of ubiquitin ligases	Professor Jose Villadangos	Biochemistry and Pharmacology
Immunosurveillance pathways in brain cancer	Project Leader Dr Alexander David Barrow	Microbiology and Immunology
Investigating the Dystrophin-Glycoprotein Complex to Protect Muscles from Wasting Conditions	Research Project Leader Professor Gordon Lynch	Anatomy and Physiology
Investigating the role of cachexia in the response to surgical tumour resection in mice	Research Project Leader Professor Gordon Lynch	Anatomy and Physiology
Isabelle Rouiller laboratory	Associate Professor Isabelle Rouiller	Biochemistry and Pharmacology
Jonathan Mangum laboratory	Head of Laboratory Dr Jonathan Mangum	Biochemistry and Pharmacology
Kallies laboratory: Molecular immunology	Head of Laboratory Professor Axel Kallies	Microbiology and Immunology
Koopman laboratory: Clinical nutrition and muscle metabolism	Head of Laboratory Associate Professor René Koopman	Anatomy and Physiology
Kristin Brown laboratory	Head of Laboratory Dr Kristin Brown	Biochemistry and Pharmacology
Learning from skeletal muscles to develop new treatments for cancer	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Live imaging of cellular signalling in vascular development and disease models	Project Leader Professor Ben Hogan	Anatomy and Physiology
Liz Hinde laboratory	Head of Research Group Dr Elizabeth Hinde	Biochemistry and Pharmacology
Lynch laboratory: Basic and clinical myology	Head of Laboratory Professor Gordon Lynch	Anatomy and Physiology
Manipulating immunity to fight infection and tumours	A/Prof Justine Mintern	Biochemistry and Pharmacology
Mantamadiotis laboratory: Brain Cancer Molecular Biology	Dr Theo Mantamadiotis	Microbiology and Immunology
Metabolic reprogramming and chemotherapy resistance in triple-negative breast cancer	Project Leader Dr Kristin Brown	Biochemistry and Pharmacology
Metabolic reprogramming of skeletal muscle stem cells	Research Project Leader Professor Gordon Lynch	Anatomy and Physiology
Michael Parker laboratory	Head of Laboratory and Director, Bio21 Institute Professor Michael Parker	Biochemistry and Pharmacology
Molecular basis for growth factor surveillance in natural killer cells	Dr Alexander David Barrow	Microbiology and Immunology
Molecular basis for growth factor surveillance in natural killer cells	Project Leader Dr Alexander David Barrow	Microbiology and Immunology
Molecular basis for growth factor surveillance in plasmacytoid dendritic cells	Dr Alexander David Barrow	Microbiology and Immunology
Molecular basis for growth factor surveillance in plasmacytoid dendritic cells	Project Leader Dr Alexander David Barrow	Microbiology and Immunology
Molecular mechanisms controlling lymphangiogenesis	Project Leader Professor Ben Hogan	Anatomy and Physiology
Molecular mechanisms of drug resistance in cancer	Project Leader Dr Jonathon Mangum	Biochemistry and Pharmacology
MR1 – a molecular alarm system that detects pathogen metabolites	Professor Jose Villadangos	Microbiology and Immunology
Mueller laboratory: Visualising the immune system in action	Head of Laboratory Professor Scott Mueller	Microbiology and Immunology
Novel regulators of germline stem cells	Project Leader Professor Gary HIme	Anatomy and Physiology
Personalising treatments for genetic diseases	Dr David Ascher	Biochemistry and Pharmacology
Precursor exhausted T cells in chronic infection and tumors	Project Leader Professor Axel Kallies	Microbiology and Immunology
Project 1. Development of improved cancer vaccines to enhance the efficacy of immunotherapy combination strategies	Project Leader Professor Riccardo Dolcetti	Microbiology and Immunology
Project 2. Identification and characterisation of novel classes of therapeutically relevant tumour neo-antigens	Project Leader Professor Riccardo Dolcetti	Microbiology and Immunology
Rational Protein Engineering	Dr David Ascher	Biochemistry and Pharmacology
Resident memory T cells (Trm)	Project Leader Professor Axel Kallies	Microbiology and Immunology
Sex-specific regulation of adipose tissue immune cells	Project Leader Professor Axel Kallies	Microbiology and Immunology
Shabih Shakeel laboratory	Lab Head & Principal Research Fellow Dr Shabih Shakeel	Biochemistry and Pharmacology
Small molecules for BIG targets- Targeting protein-protein interactions with fragments	Dr David Ascher	Biochemistry and Pharmacology
Structural Biology of Cancer	Professor Michael Parker	Biochemistry and Pharmacology
Tackling drug resistance	Dr David Ascher	Biochemistry and Pharmacology
Taylor: Jack Brockhoff Reconstructive Plastic Surgery Research Unit	Head of Research Unit Professor Ian Taylor	Anatomy and Physiology
The Bonn and Melbourne Research and Graduate School	Melbourne Coordinator Dr Marie Greyer
Therapeutic potential of skeletal muscle plasticity and slow muscle programming for muscular dystrophy	Research Project Leader Professor Gordon Lynch	Anatomy and Physiology
Transcriptional regulation of cancer cell metabolism	Project Leader Dr Kristin Brown	Biochemistry and Pharmacology
Transcriptional regulation of intestinal organoid differentiation	Project Leader Professor Gary Hime	Anatomy and Physiology
Transcriptional reprogramming of metabolism in liver cancer	Project Leader Dr Andrew Cox	Biochemistry and Pharmacology
Understanding how the ATPase p97 functions at molecular level	Associate Professor Isabelle Rouiller	Biochemistry and Pharmacology
Understanding immune dysfunction in acute myeloid leukemia	A/Prof Justine Mintern	Biochemistry and Pharmacology
Understanding the immune microenvironment in brain tumours	Dr Theo Mantamadiotis	Microbiology and Immunology
Understanding the Molecular Consequences of Mutations	Dr David Ascher David Ascher	Biochemistry and Pharmacology
Unravelling the mysteries of E3 ubiquitin ligase in regulating skeletal muscle size and function	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Using the immune system to kill tumours	A/Prof Justine Mintern	Biochemistry and Pharmacology
Using transcriptional analyses to understand recognition of tumours by natural killer cells	Professor Andrew Brooks	Microbiology and Immunology
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Anatomy and Physiology

Cardio-Respiratory

Groups / Projects	Research Lead	Dept / Centre
Allen laboratory: Central cardiovascular regulation	Head of Laboratory Professor Andrew Allen	Anatomy and Physiology
Brain networks processing respiratory sensations	Project Leader Professor Stuart Mazzone	Anatomy and Physiology
Christine Wright laboratory	Head of Laboratory Associate Professor Christine E Wright	Biochemistry and Pharmacology
David Stroud laboratory	Head of Research Group Dr David Stroud	Biochemistry and Pharmacology
Delbridge laboratory: Cardiac phenomics	Head of Laboratory Professor Lea Delbridge	Anatomy and Physiology
Diabetic cardiomyopathy – an epidemic disease	Research Project Leader Professor Lea Delbridge	Anatomy and Physiology
Effects of hypertension on renal and hindquarter vascular reactivity in vivo and in vitro	Project Leader Associate Professor Christine Wright	Biochemistry and Pharmacology
Elena Schneider-Futschik laboratory	Head of Laboratory Dr Elena Schneider-Futschik	Biochemistry and Pharmacology
Endothelin pharmacology in the setting of pulmonary hypertension	Project Leader Professor James Angus	Biochemistry and Pharmacology
Functional genomic screens for cardiovascular drug discovery	Research Project Leader Dr Enzo Porrello	Anatomy and Physiology
Functional neuroanatomy of genitourinary vasculature	Project Leaders Professor Janet Keast / Dr Peregrine Osborne	Anatomy and Physiology
Human brain networks processing respiratory sensations	Project Leader Professor Stuart Mazzone	Anatomy and Physiology
Improving the diagnostic outcomes of patients with mitochondrial disease	Dr David Stroud	Biochemistry and Pharmacology
Lung Disease Research Laboratory	Head of Laboratory Professor Gary P Anderson	Biochemistry and Pharmacology
Manipulating the endocannabinoid system to alter cardiovascular function in hypertension	Dr Makhala Khammy	Pharmacology and Therapeutics
Mazzone laboratory: Respiratory Sensory Neuroscience	Head of Research Group Professor Stuart Mazzone	Anatomy and Physiology
Mechanisms of diastolic heart failure	Research Project Leader Professor Lea Delbridge	Anatomy and Physiology
Modeling human heart development using human cardiac organoids	Research Project Leader Dr Enzo Porrello	Anatomy and Physiology
Montgomery laboratory: Metabolic Tissue Cross-Talk	Head of Laboratory Dr Magdalene Montgomery	Anatomy and Physiology
Novel technique to determine the pKA of clonidine at prejunctional α2-adrenoceptors in sympathetic transmission	Project Leader Professor James Angus	Biochemistry and Pharmacology
Pathogenesis of chronic lung disease	Head of Laboratory Dr Michelle Hansen	Biochemistry and Pharmacology
Porrello laboratory: Cardiac Regeneration	Head of Laboratory Enzo Porrello	Anatomy and Physiology
Post-natal control of cardiac gene regulatory networks	Research Project Leader Dr Enzo Porrello	Anatomy and Physiology
Preclinical pharmacology – cardiovascular efficacy and safety R&D	Project Leader Associate Professor Christine Wright	Biochemistry and Pharmacology
Reassessment of α1-adrenoceptor mechanism in artery contraction: role of ATP and pannexin channels	Project Leader Professor James Angus	Biochemistry and Pharmacology
Sex, adiposity and cardiac vulnerability	Research Project Leader Professor Lea Delbridge	Anatomy and Physiology
Smith laboratory: Cardiac Genetics	Head of Laboratory Associate Professor Kelly Smith	Anatomy and Physiology
The amyloidogenic protease inhibitor Cystatin C in health and disease	Prof Jose Villadangos	Biochemistry and Pharmacology
The cardiovascular pharmacology of snake venoms from Papua New Guinea and Australia	Project Leader Associate Professor Christine Wright	Biochemistry and Pharmacology
The innate immune system in the respiratory tract	Project Leader Professor David Jackson	Microbiology and Immunology
The link between cardiovascular disease and neurodegeneration – focus on Alzheimer’s disease	Project Leader Associate Professor Christine Wright	Biochemistry and Pharmacology
Transcriptional profiling of sensory neurons	Project Leader Professor Stuart Mazzone	Anatomy and Physiology
Trovafloxacin – an antibiotic with additional properties	Project Leader Professor James Angus	Biochemistry and Pharmacology
Understanding the assembly of mitochondrial machines	Dr David Stroud	Biochemistry and Pharmacology
Yao laboratory: Cardiovascular Neuroscience	Head of Laboratory Dr Song Yao	Anatomy and Physiology

Cell Signalling

Groups / Projects	Research Lead	Dept / Centre
Analysing genetic roles of RNA-binding proteins and alternative splicing in Drosophila stem cells	Project Leader Professor Gary Hime	Anatomy and Physiology
Assembly of the Commander complex	Prof David Stroud
Bedoui laboratory: Innate and adaptive interactions in immunity to infection	Head of Laboratory Professor Sammy Bedoui	Microbiology and Immunology
Biogenesis of mitochondrial complexes	Prof David Stroud
Building a urogenital nervous system connectome	Project Leaders Professor Janet Keast / Dr Peregrine Osborne	Anatomy and Physiology
Cell Signalling
Cellular trafficking and male fertility	Project Leader Professor Gary Hime	Anatomy and Physiology
Characterisation of the changes of the endocytic and secretory pathway of dendritic cells upon activation	A/Prof Isabelle Rouiller	Biochemistry and Pharmacology
Characterising the pathways responsible for ICU-acquired weakness	Research Project Leader Dr René Koopman	Anatomy and Physiology
Cutting off the fuel supply to starve cancer: identifying the nutrient dependencies of cancer cells	Project Leader Dr Kristin Brown	Biochemistry and Pharmacology
Decoding the trafficking of immune receptors	A/Prof Justine Mintern	Biochemistry and Pharmacology
Defining new roles for the Hippo signalling pathway in skeletal muscle	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Delbridge laboratory: Cardiac phenomics	Head of Laboratory Professor Lea Delbridge	Anatomy and Physiology
Designing new optogenetic tools for biomedical research	A/Prof Danny Hatters	Biochemistry and Pharmacology
Determining the molecular basis of disease-causing mutations in synaptic proteins.	Dr Daniel Scott	Biochemistry and Pharmacology
Developing a novel class of therapeutics for muscle wasting and frailty	Research Project Leader Dr Benjamin Parker	Anatomy and Physiology
Developing innovative animal and cell culture models to study and treat muscular dystrophies	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Development of an electromechanical flow-cytometry based cell stimulation system	Dr Daniel Scott	Biochemistry and Pharmacology
Development of Novel Antimalarial Drugs	Prof Leann Tilley
Diabetic cardiomyopathy – an epidemic disease	Research Project Leader Professor Lea Delbridge	Anatomy and Physiology
Discovering and characterizing new genes involved in innate immunity, tissue injury and fibrosis	Project Leader Professor Christine Wells	Anatomy and Physiology
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Research Project Leader Professor Matthew Watt	Anatomy and Physiology
Engineering G protein-coupled receptors for structural biology and drug discovery with directed evolution.	Dr Daniel Scott	Biochemistry and Pharmacology
Establishing the effect of glycine/serine metabolism on skeletal muscle cell growth	Research Project Leader Dr René Koopman	Anatomy and Physiology
Exercise-induced liver-muscle cross-talk and mitochondrial adaptations	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
Exploiting nanoparticles as vaccines	A/Prof Justine Mintern	Biochemistry and Pharmacology
Exploring new roles for the TGFβ signalling network as a key regulator of skeletal muscle in health and disease	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Fragment-based drug discovery using stabilized α1-adrenoceptors	Dr Daniel Scott	Biochemistry and Pharmacology
Functional neuroanatomy of genitourinary vasculature	Project Leaders Professor Janet Keast / Dr Peregrine Osborne	Anatomy and Physiology
Genetics of blood brain barrier formation	Project Leader Professor Ben Hogan	Anatomy and Physiology
Gregorevic laboratory: Muscle Research and Therapeutics	Head of Laboratory Associate Professor Paul Gregorevic	Anatomy and Physiology
Gunnersen laboratory: Neuron development and plasticity	Head of Laboratory Associate Professor Jenny Gunnersen	Anatomy and Physiology
Hogan laboratory: Vascular Cell and Developmental Biology	Head of Laboratory Professor Ben Hogan	Anatomy and Physiology
How to design a better GPCR drug: understanding the structural basis of ligand selectivity at α1-adrenoceptors.	Dr Daniel Scott	Biochemistry and Pharmacology
Immune responses to pathogenic bacteria	Prof Ian van Driel
Immuno-paralysis following severe infections	Prof Jose Villadangos
Improving the formation of protective immunity against human viruses	Prof Jose Villadangos
Keast & Osborne laboratory: Neural and Bioelectronic Control of Pelvic Organs	Joint Heads of Laboratory Professor Janet Keast & Dr Peregrine Osborne	Anatomy and Physiology
Kristin Brown laboratory	Head of Laboratory Dr Kristin Brown	Biochemistry and Pharmacology
Learning from skeletal muscles to develop new treatments for cancer	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Live imaging of cellular signalling in vascular development and disease models	Project Leader Professor Ben Hogan	Anatomy and Physiology
Liz Hinde laboratory	Head of Research Group Dr Elizabeth Hinde	Biochemistry and Pharmacology
Mantamadiotis laboratory: Brain Cancer Molecular Biology	Dr Theo Mantamadiotis	Microbiology and Immunology
Mechanisms of diastolic heart failure	Research Project Leader Professor Lea Delbridge	Anatomy and Physiology
Metabolic reprogramming and chemotherapy resistance in triple-negative breast cancer	Project Leader Dr Kristin Brown	Biochemistry and Pharmacology
Michael Parker laboratory	Head of Laboratory and Director, Bio21 Institute Professor Michael Parker	Biochemistry and Pharmacology
Mitochondria as targets during bacterial pathogenesis	Prof Diana Stojanovski
Molecular mechanisms controlling lymphangiogenesis	Project Leader Professor Ben Hogan	Anatomy and Physiology
Montgomery laboratory: Metabolic Tissue Cross-Talk	Head of Laboratory Dr Magdalene Montgomery	Anatomy and Physiology
MR1 – a molecular alarm system for bacterial infection	Prof Jose Villadangos
Multi-omic analysis of exercise induced changes to mitochondria	Prof David Stroud
Murray laboratory: Myelin biology	Head of Laboratory Associate Professor Simon Murray	Anatomy and Physiology
Novel regulators of germline stem cells	Project Leader Professor Gary HIme	Anatomy and Physiology
Parker laboratory: Metabolic Proteomics & Signal Transduction	Head of Laboratory Dr Benjamin Parker	Anatomy and Physiology
Paul Gleeson laboratory	Head of Laboratory Professor Paul Gleeson	Biochemistry and Pharmacology
Peter Crack laboratory	Head of Laboratory Associate Professor Peter Crack	Biochemistry and Pharmacology
Role of interferon inducible GTPases in immune defence	Prof Ian van Driel
Sex, adiposity and cardiac vulnerability	Research Project Leader Professor Lea Delbridge	Anatomy and Physiology
Skeletal muscle signal transduction related to exercise, metabolic disease and human health	Research Project Leader Dr Benjamin Parker	Anatomy and Physiology
Smith laboratory: Cardiac Genetics	Head of Laboratory Associate Professor Kelly Smith	Anatomy and Physiology
Structural Biology of Cancer	Professor Michael Parker	Biochemistry and Pharmacology
Structural Neurobiology	Professor Michael Parker	Biochemistry and Pharmacology
Systems genetics of muscle metabolism	Research Project Leader Dr Benjamin Parker	Anatomy and Physiology
The Bonn and Melbourne Research and Graduate School	Melbourne Coordinator Dr Marie Greyer
The heart as a central player in tissue cross-talk	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
The immune signature of COVID-19 patients	Prof Jose Villadangos
The machines and pathways that facilitate mitochondrial protein import in human cells	Dr Diana Stojanovski
The role of protein modifications on muscle development	Research Project Leader Dr Benjamin Parker	Anatomy and Physiology
Tissue communication in non-alcoholic fatty liver disease (NALFD) and liver fibrosis	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
Transcriptional regulation of cancer cell metabolism	Project Leader Dr Kristin Brown	Biochemistry and Pharmacology
Transcriptional regulation of intestinal organoid differentiation	Project Leader Professor Gary Hime	Anatomy and Physiology
Trogocytosis: a novel communication system between cells of the immune system	Prof Jose Villadangos
Ultrasonically driven neuromodulation using mechano-responsive proteins	Dr Daniel Scott	Biochemistry and Pharmacology
Uncovering the interplay between innate immunity and the blood brain barrier in disorders of the CNS	Project Leader Professor Christine Wells	Anatomy and Physiology
Understanding immune dysfunction in acute myeloid leukemia	A/Prof Justine Mintern	Biochemistry and Pharmacology
Understanding metabolic cross-talk in health and disease - Focus on type 2 diabetes and fatty liver	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
Understanding the interaction between microbiota and T cell immunity	Project Leader Professor Sammy Bedoui	Microbiology and Immunology
Understanding the structural basis of peptide-activated G protein-coupled receptor signalling to enable drug discovery.	Dr Daniel Scott	Biochemistry and Pharmacology
Unravelling the mysteries of E3 ubiquitin ligase in regulating skeletal muscle size and function	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Using proteomics to diagnose mitochondrial disease	Prof David Stroud
Using the immune system to kill tumours	A/Prof Justine Mintern	Biochemistry and Pharmacology
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Anatomy and Physiology

Cellular Imaging & Structural Biology

Groups / Projects	Research Lead	Dept / Centre
Adverse maternal environment in females born small and transgenerational consequences	Research Project Leader Professor Mary Wlodek	Anatomy and Physiology
Bacterial secretion systems	Project Leader Dr Debnath Ghosal	Biochemistry and Pharmacology
Being born small programs growth restriction, deficits and disease in the next generation	Research Project Leader Professor Mary Wlodek	Anatomy and Physiology
Cellular Imaging & Structural Biology
Danny Hatters laboratory	Head of Laboratory Professor Danny Hatters	Biochemistry and Pharmacology
Debnath Ghosal laboratory	Head of Laboratory Dr Debnath Ghosal	Biochemistry and Pharmacology
Deciphering structures of bacterial and viral molecular machines that inject toxins into our cells	Dr. Debnath Ghosal	Biochemistry and Pharmacology
Dendritic cell maturation following different microbial stimulation	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Diana Stojanovski laboratory	Head of Laboratory Dr Diana Stojanovski	Biochemistry and Pharmacology
Early life exercise reprograms pancreatic and heart deficits in offspring born small	Research Project Leader Professor Mary Wlodek	Anatomy and Physiology
Factors that accelerate photoreceptor death: The role of purines	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
Fletcher laboratory: Visual neuroscience	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
Glial cells as a source of progenitor cells in degenerative disease	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
Gunnersen laboratory: Neuron development and plasticity	Head of Laboratory Associate Professor Jenny Gunnersen	Anatomy and Physiology
Harnessing local immunity to block the development of secondary bacterial pneumonia	Project Leader Dr Linda Wakim	Microbiology and Immunology
Heath laboratory: CD8 T lymphocytes, dendritic cells, self tolerance and immunity	Head of Laboratory Professor William (Bill) Heath	Microbiology and Immunology
Imaging effector and memory T cell responses in the skin following Herpes Simplex Virus-1 infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Imaging the priming of CD8 Killer T cell responses to Herpes Simplex Virus-1 skin infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Improved vaccines by targeting to dendritic cells	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Intraepithelial T cells in anti-viral immunity	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
Intravital imaging of T cell responses in the brain during cerebral malaria infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Investigating the mechanism of action of the antiviral molecule, IFITM3	Project Leader Dr Linda Wakim	Microbiology and Immunology
Isabelle Rouiller laboratory	Associate Professor Isabelle Rouiller	Biochemistry and Pharmacology
Keast & Osborne laboratory: Neural and Bioelectronic Control of Pelvic Organs	Joint Heads of Laboratory Professor Janet Keast & Dr Peregrine Osborne	Anatomy and Physiology
Leann Tilley laboratory	Head of Laboratory, Redmond Barry Distinguished Professor of Biochemistry & Pharmacology, ARC Australian Laureate Fellow (2015-2020) Professor Leann Tilley	Biochemistry and Pharmacology
Liz Hinde laboratory	Head of Research Group Dr Elizabeth Hinde	Biochemistry and Pharmacology
Lymphoid stromal cells and control of immunity to infection and cancer	Project Leader Professor Scott Mueller	Microbiology and Immunology
Malaria and Tissue Resident Memory T cells (TRM) in the liver	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Malaria parasite-infected red blood cells: a renovator’s dream	Professor Leann Tilley	Biochemistry and Pharmacology
Mueller laboratory: Visualising the immune system in action	Head of Laboratory Professor Scott Mueller	Microbiology and Immunology
Murray laboratory: Myelin biology	Head of Laboratory Associate Professor Simon Murray	Anatomy and Physiology
Neural regulation of immunity	Project Leader Professor Scott Mueller	Microbiology and Immunology
Neuroanatomy of human visceral systems	Professor Janet Keast	Anatomy and Physiology
Paul Gleeson laboratory	Head of Laboratory Professor Paul Gleeson	Biochemistry and Pharmacology
Paul Gooley laboratory	Head of Laboratory Professor Paul Gooley	Biochemistry and Pharmacology
Priming of T cell responses to viral infection	Project Leader Professor Scott Mueller	Microbiology and Immunology
Protein trafficking and cellular architecture	Professor Leann Tilley	Biochemistry and Pharmacology
Self-tolerance: Interactions between thymic stroma and dendritic cells	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Shabih Shakeel laboratory	Lab Head & Principal Research Fellow Dr Shabih Shakeel	Biochemistry and Pharmacology
Solving the native structure of the malaria parasite using cryo-electron microscopy	Professor Leann Tilley	Biochemistry and Pharmacology
Structure and function of bacterial "cytomotive" filaments	Project Leader Dr Debnath Ghosal	Biochemistry and Pharmacology
T cell responses in the brain during experimental cerebral malaria infection	Project Leader Professor Scott Mueller	Microbiology and Immunology
Taylor: Jack Brockhoff Reconstructive Plastic Surgery Research Unit	Head of Research Unit Professor Ian Taylor	Anatomy and Physiology
The Bonn and Melbourne Research and Graduate School	Melbourne Coordinator Dr Marie Greyer
The role of glia in inner retinal changes during retinal degeneration	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
The role of glial cells in retinal vascular disease	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
The role of microglia in age-related macular degeneration	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
Tissue-resident memory T cells	Project Leader Professor Scott Mueller	Microbiology and Immunology
Vaccination against liver-stage Plasmodium for malaria prevention	Project Leader Professor William (Bill) Heath	Microbiology and Immunology

Infection & Immunity

Groups / Projects	Research Lead	Dept / Centre
A cell-based model of sporadic prion disease	Associate Professor Vicki Lawson	Microbiology and Immunology
Age-dependent susceptibility of neurons to RNA virus infection	Dr Lukasz Kedzierski	Microbiology and Immunology
Antibodies preventing HTLV-1c infection	Professor Damian Purcell	Microbiology and Immunology
Application of systems genomics to analysing the dynamics of Streptococcus pyogenes infection	Dr Mark Davies	Microbiology and Immunology
Are there additional MAIT cell antigens?	Dr Sidonia Eckle	Microbiology and Immunology
Blocking the development of secondary bacterial pneumonia	Dr Linda Wakim	Microbiology and Immunology
Can resident memory B cells in the lung protect against respiratory syncytial virus?	Professor Stephen Kent	Microbiology and Immunology
CCVs: Clathrin-coated vesicles and Coxiella containing vacuoles	Dr Hayley Newton	Microbiology and Immunology
Characterisation of antimicrobial resistance and virulence of novel staphylococcal lineages	Associate Professor Steven Tong	Microbiology and Immunology
Clinical metagenomics for rapid diagnosis of drug resistant tuberculosis	Dr Sarah Dunstan	Microbiology and Immunology
Coin Laboratory: Genomics and bioinformatics in infectious disease and cancer	Head of Laboratory Professor Lachlan Coin	Microbiology and Immunology
Corbett Laboratory: Mucosal-Associated Invariant T cell detection of microbial metabolites, activation and immune function	Head of Laboratory A/Prof Alexandra Corbett	Microbiology and Immunology
Cow antibodies that give the finger to HIV transmission	Professor Damian Purcell	Microbiology and Immunology
Day Laboratory: Malaria genomics, epidemiology and control	Head of Laboratory Professor Karen Day	Microbiology and Immunology
Defining the association between virulence and fitness of seasonal influenza viruses	Professor Kanta Subbarao	Microbiology and Immunology
Defining the impact of recurrent adaptive mutations on staphylococcal antimicrobial resistance and pathogenesis	Professor Ben Howden	Microbiology and Immunology
Design and development of antibiotics against multidrug resistant bacteria	Project Leader Associate Professor Tony Velkov	Biochemistry and Pharmacology
Design of inhibitory drugs for molecular components of the siderophore biosynthetic pathway that are crucial for iron sequestration during mycobacterium tuberculosis (TB) pathogenesis	Project Leader Associate Professor Tony Velkov	Biochemistry and Pharmacology
Determining the role of diet and microbiota in the progression of lupus	Professor Fabienne Mackay	Microbiology and Immunology
Development of novel proteomic tools to explore Burkholderia pathogenesis	Dr Nichollas Scott	Microbiology and Immunology
Diagnosis, treatment and prevention of medically relevant prion diseases	Associate Professor Vicki Lawson	Microbiology and Immunology
Evolution of streptococcal pathovars	Dr Mark Davies	Microbiology and Immunology
Evolutionary Genetics of avian influenza A viruses in Australia	Dr Michelle Wille	Microbiology and Immunology
Gamma delta T cells are important for malaria sporozoite vaccination	Dr Lynette Beattie	Microbiology and Immunology
Genomic epidemiology and malaria surveillance	Project Leader Professor Karen Day	Microbiology and Immunology
Haque Laboratory	Head of Laboratory Associate Professor Ashraful Haque	Microbiology and Immunology
Harnessing the molecular clock to activate diverse strains of latent HIV	Professor Sharon Lewin	Microbiology and Immunology
How do tumours impact normal tissue functions?	Associate Professor Scott Mueller	Microbiology and Immunology
How does ageing affect antibody responses?	Project Leader Dr Amy Chung	Microbiology and Immunology
How does ageing effect antibody responses?	Dr Amy Chung	Microbiology and Immunology
How is selective metal ion transport achieved at the host-pathogen interface?	Associate Professor Christopher McDevitt	Microbiology and Immunology
Ian van Driel laboratory	Head of Laboratory Professor Ian van Driel	Biochemistry and Pharmacology
Identification and characterisation of novel malarial transmission-blocking antigens	Associate Professor Siddhartha Mahanty	Microbiology and Immunology
Identifying novel subsets of immune cells that control cytomegalovirus following transplantation	Dr Lucy Sullivan	Microbiology and Immunology
Illuminating microbial “dark matter” for antibiotic discovery	Dr Sacha Pidot	Microbiology and Immunology
Immuno-paralysis following severe infections or trauma	Professor Jose Villadangos	Microbiology and Immunology
Immunoregulatory functions of the MARCH family of ubiquitin ligases	Professor Jose Villadangos	Microbiology and Immunology
Impact of Seasonal Malaria Chemoprevention on drug resistance biomarkers and antigenic diversity	Professor Karen Day	Microbiology and Immunology
Infection & Immunity
Infection induced changes to splenic macrophages	Dr Lynette Beattie	Microbiology and Immunology
Integrative infectious disease phylodynamics	Dr Sebastian Duchene	Microbiology and Immunology
Investigating antimalarial drug resistance in response to community interventions in Ghana, West Africa	Project Leader Professor Karen Day	Microbiology and Immunology
Investigating novel chromatin proteins of the malaria parasite P. falciparum as drug targets.	Dr Michael Duffy	Microbiology and Immunology
Investigating the diversity of the variant antigen genes of Plasmodium falciparum	Project Leader Professor Karen Day	Microbiology and Immunology
Investigating the effect of hepatitis B virus splice variants in liver cells and disease progression	Professor Peter Revill	Microbiology and Immunology
Investigating the role of functional antibodies against Mycobacterium tuberculosis	Dr Amy Chung	Microbiology and Immunology
Justine Mintern laboratory	Head of Laboratory A/Prof Justine Mintern	Biochemistry and Pharmacology
Leann Tilley laboratory	Head of Laboratory, Redmond Barry Distinguished Professor of Biochemistry & Pharmacology, ARC Australian Laureate Fellow (2015-2020) Professor Leann Tilley	Biochemistry and Pharmacology
Location, location, location – lodging virus specific T cells in the lung as an approach to protecting against influenza virus infection	Dr Linda Wakim	Microbiology and Immunology
Mackenzie laboratory: Intracellular virus replication and innate immunity	Head of Laboratory Professor Jason Mackenzie	Microbiology and Immunology
Malcolm McConville laboratory	Head of Laboratory Professor Malcolm McConville	Biochemistry and Pharmacology
Manipulating MAIT cells for increased protection by vaccination and therapy	Dr Alexandra Corbett	Microbiology and Immunology
Mapping elemental fluxes during host-pathogen interaction	Associate Professor Christopher McDevitt	Microbiology and Immunology
Metal ion homeostasis in Klebsiella pneumoniae	Associate Professor Christopher McDevitt	Microbiology and Immunology
Mitochondria and intracellular bacterial pathogens	Dr Hayley Newton	Microbiology and Immunology
Molecular basis for growth factor surveillance in plasmacytoid dendritic cells	Dr Alexander David Barrow	Microbiology and Immunology
MR1 – a molecular alarm system for bacterial infection	Dr Hamish McWilliam	Microbiology and Immunology
Neural regulation of anti-cancer immunity	Associate Professor Scott Mueller	Microbiology and Immunology
Neurodegeneration in the enteric nervous system	Associate Professor Vicki Lawson	Microbiology and Immunology
New antibiotics from old bacteria	Dr Sacha Pidot	Microbiology and Immunology
Novel master-regulators of B-cell biology	Professor Fabienne Mackay	Microbiology and Immunology
Pathogenesis of HTLV-1 subtype-C infecting remote indigenous Australians	Professor Damian Purcell	Microbiology and Immunology
Pathogenesis of pneumococcal pneumonia	Associate Professor Catherine Satzke	Microbiology and Immunology
Pidot Laboratory: Antibiotic Discovery and Biosynthesis	Head of Laboratory Dr Sacha Pidot	Microbiology and Immunology
Plasma protein binding of antibiotics	Project Leader Associate Professor Tony Velkov	Biochemistry and Pharmacology
Population genomics of endemic Streptococcus pyogenes	Dr Mark Davies	Microbiology and Immunology
Preventing infections of the highly puke-ogenic virus - norovirus	Professor Jason Mackenzie	Microbiology and Immunology
Programming gamma delta T cells for HIV immunotherapy	Professor Stephen Kent	Microbiology and Immunology
Project 1. How do CD4+ T cells preserve memories during malaria?	Head of Laboratory Associate Professor Ashraful Haque	Microbiology and Immunology
Project 2. CD4+ T cells in acute Graft-versus-Host Disease	Head of Laboratory Associate Professor Ashraful Haque	Microbiology and Immunology
Project 3. Do malaria parasites sense and respond to the host during infection?	Head of Laboratory Associate Professor Ashraful Haque	Microbiology and Immunology
Protective capacity of malaria-specific liver-tissue-resident memory T cells	Dr Lauren Holz	Microbiology and Immunology
Quantifying bacterial recombination within globally evolving streptococcal pathogens	Dr Mark Davies	Microbiology and Immunology
Quorum sensing in malaria	Professor Karen Day	Microbiology and Immunology
Regeneration of lymphoid tissues	Associate Professor Scot Mueller	Microbiology and Immunology
RNA control of HIV latency	Professor Damian Purcell	Microbiology and Immunology
Role of O-linked glycosylation system across the Burkholderia genus	Dr Nichollas Scott	Microbiology and Immunology
Role of suppressor of cytokine signalling proteins in viral encephalitis	Dr Lukasz Kedzierski	Microbiology and Immunology
Scott Laboratory: Microbial glycoproteomics and host pathogen interactions	Head of Laboratory Dr Nichollas Scott	Microbiology and Immunology
SNAP - Staphylococcus aureus Network Adaptive Platform Trial	Associate Professor Steven Tong	Microbiology and Immunology
Staphylococcus aureus bloodstream infections in Victorian hospitals: regional differences in disease burden and epidemiology	Associate Professor Leon Worth	Microbiology and Immunology
Streptococcal transmission and disease	Associate Professor Catherine Satzke	Microbiology and Immunology
Synergistic and antagonistic interplay between Streptococcus pneumoniae and respiratory viruses	Associate Professor Catherine Satzke	Microbiology and Immunology
Testing a novel strategy to target chronic lymphocytic leukemia	Professor Fabienne Mackay	Microbiology and Immunology
The importance of IgA in the protection and control of infectious diseases	Dr Amy Chung	Microbiology and Immunology
The importance of IgA in the protection and control of infectious diseases	Project Leader Dr Amy Chung	Microbiology and Immunology
The role of co-pathologies in the clinical presentation of prion disease	Associate Professor Vicki Lawson	Microbiology and Immunology
The role of glucose metabolism in the regulation of immunity	Professor Jose Villadangos	Microbiology and Immunology
The role of the prion protein in brain cancer	Associate Professor Vicki Lawson	Microbiology and Immunology
The space of evolutionary trees in infectious disease epidemiology	Dr Sebastian Duchene	Microbiology and Immunology
Understanding essential gene regulation in Staphylococcus aureus	Professor Tim Stinear	Microbiology and Immunology
Understanding the biological chemistry of pneumococcal disease	Associate Professor Christopher McDevitt	Microbiology and Immunology
Understanding the importance of variation in the capsular polysaccharide of Streptococcus pneumoniae	Associate Professor Catherine Satzke	Microbiology and Immunology
Understanding the mechanisms that impair anti-tumour adoptive cell therapy	Professor Jose Villadangos	Microbiology and Immunology
Understanding the role of MAIT cells in immune-mediated pathology	Dr Sidonia Eckle	Microbiology and Immunology
Understanding the role of MAIT cells in protection from microbial infections	Dr Sidonia Eckle	Microbiology and Immunology
Unravelling the drivers of scarlet fever pandemics	Dr Mark Davies	Microbiology and Immunology
Using genomics to investigate the transmission of skin pathogens and antimicrobial resistance in a ‘One Health’ setting	Dr Mark Davies	Microbiology and Immunology
Using genomics to track transmission of Chlamydia trachomatis	Dr Hayley Newton	Microbiology and Immunology
Using transcriptional analyses to understand recognition of tumours by natural killer cells	Professor Andrew Brooks	Microbiology and Immunology
Validating human transgenic mouse models for lupus therapeutics development	Professor Fabienne Mackay	Microbiology and Immunology
Vertical transmission of Ross River virus in mosquito vectors	Dr Julio Rodriguez-Andres	Microbiology and Immunology
What do antibodies need to do to protect a woman against pregnancy-malaria?	Dr Elizabeth Aitken	Microbiology and Immunology
Whole body analysis of human tissue-resident memory T cells	Dr Claire Gordon	Microbiology and Immunology
Why is the flavivirus RdRp in the nucleus?	Professor Jason Mackenzie	Microbiology and Immunology

105

Molecular Mechanisms of Disease

Groups / Projects	Research Lead	Dept / Centre
Understanding the plasticity of skeletal muscle in health and disease	Research Project Leader Professor Gordon Lynch	Anatomy and Physiology
"Clock-off time" for inflammation and remodelling in chronic inflammatory diseases: casein kinase inhibitors	Primary Supervisor Professor Alastair Stewart	Biochemistry and Pharmacology
A novel link between metabolism and host defence: O-GlcNAc glycosylation	Professor Jose Villadangos	Biochemistry and Pharmacology
A universal vaccine against influenza A	Project Leader Professor David Jackson	Microbiology and Immunology
Adaptive remodelling of metabolism during liver regeneration	Project Leader Dr Andrew Cox	Biochemistry and Pharmacology
Analysing protein structures	Dr David Ascher	Biochemistry and Pharmacology
Andrew Cox laboratory	Head of Laboratory Dr Andrew Cox	Biochemistry and Pharmacology
Angiotensin and chemoreceptor function	Research Project Leader Professor Andrew Allen	Anatomy and Physiology
Antibody dependent cellular cytotoxicity - a neglected anti-HIV iImmune response!	Project Leaders Professor Stephen Kent & Dr Amy Chung	Microbiology and Immunology
Antimicrobial resistant bacterial pathogens	Project Leader Professor Ben Howden	Microbiology and Immunology
Application of genomics to public health and clinical microbiology	Project Leader Professor Ben Howden	Microbiology and Immunology
Applications of Nanopore sequencing	Project Leader Dr Mike Clark	Anatomy and Physiology
Autophagy and Norovirus replication	Professor Jason Mackenzie	Microbiology and Immunology
Bacterial secretion systems	Project Leader Dr Debnath Ghosal	Biochemistry and Pharmacology
Bedoui laboratory: Innate and adaptive interactions in immunity to infection	Head of Laboratory Professor Sammy Bedoui	Microbiology and Immunology
Biolpolymer-based vaccine delivery systems	Project Leader Professor David Jackson	Microbiology and Immunology
Bornstein laboratory: Enteric neuroscience	Head of Laboratory Professor Joel C Bornstein	Anatomy and Physiology
Brain networks processing respiratory sensations	Project Leader Professor Stuart Mazzone	Anatomy and Physiology
Brooks laboratory: Innate immunity; anti-viral immunity	Head of Laboratory Professor Andrew Brooks	Microbiology and Immunology
Building a urogenital nervous system connectome	Project Leaders Professor Janet Keast / Dr Peregrine Osborne	Anatomy and Physiology
Cell surface receptors for attachment and entry of influenza virus into cells of the innate immune system	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
Characterising the cellular roles of metals	Research Project Leader Associate Professor Christopher McDevitt	Microbiology and Immunology
Characterising the pathways responsible for ICU-acquired weakness	Research Project Leader Dr René Koopman	Anatomy and Physiology
Chronic immune activation during treated HIV disease	Project Leader Professor Damian Purcell	Microbiology and Immunology
Chung laboratory: Investigating the role of functional antibodies against Mycobacterium tuberculosis	Head of Laboratory Dr Amy Chung	Microbiology and Immunology
Clark laboratory: Transcriptomics and Neurogenetics	Head of Laboratory Dr Mike Clark	Anatomy and Physiology
Coin Laboratory: Genomics and bioinformatics in infectious disease and cancer	Head of Laboratory Professor Lachlan Coin	Microbiology and Immunology
Correlates of severe and fatal influenza disease in high-risk groups	Head of Laboratory Associate Professor Katherine Kedzierska	Microbiology and Immunology
Peter Crouch laboratory	Head of Laboratory Dr Peter Crouch	Biochemistry and Pharmacology
Cutting off the fuel supply to starve cancer: identifying the nutrient dependencies of cancer cells	Project Leader Dr Kristin Brown	Biochemistry and Pharmacology
Daniel Hoyer laboratory	Head of Laboratory Professor Daniel Hoyer	Biochemistry and Pharmacology
Danny Hatters laboratory	Head of Laboratory Professor Danny Hatters	Biochemistry and Pharmacology
David Ascher laboratory	Head of Laboratory Dr David Ascher	Biochemistry and Pharmacology
David Stroud laboratory	Head of Research Group Dr David Stroud	Biochemistry and Pharmacology
Debnath Ghosal laboratory	Head of Laboratory Dr Debnath Ghosal	Biochemistry and Pharmacology
Deciphering structures of bacterial and viral molecular machines that inject toxins into our cells	Dr. Debnath Ghosal	Biochemistry and Pharmacology
Deciphering the relative contributions of different dendritic cells to killer T cell responses	Project Leader Professor Sammy Bedoui	Microbiology and Immunology
Decoding the trafficking of immune receptors	A/Prof Justine Mintern	Biochemistry and Pharmacology
Defining new roles for the Hippo signalling pathway in skeletal muscle	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Delbridge laboratory: Cardiac phenomics	Head of Laboratory Professor Lea Delbridge	Anatomy and Physiology
Delineating how CD4 T cells ‘help’ establishing effective killer T cell responses	Project Leader Professor Sammy Bedoui	Microbiology and Immunology
Dendritic cell maturation following different microbial stimulation	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Design, development and testing of HIV vaccines	Project Leader Professor Damian Purcell	Microbiology and Immunology
Developing a novel class of therapeutics for muscle wasting and frailty	Research Project Leader Dr Benjamin Parker	Anatomy and Physiology
Developing innovative animal and cell culture models to study and treat muscular dystrophies	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Development of a self-adjuvanting vaccine for enterotoxigenic Escherichia coli (ETEC)	Project Leader Professor David Jackson	Microbiology and Immunology
Development of autonomic and nociceptive circuits	Project Leaders Professor Janet Keast / Dr Peregrine Osborne	Anatomy and Physiology
Development of effector regulatory T cells	Project Leader Professor Axel Kallies	Microbiology and Immunology
Development of new types of antimicrobial agents	Project Leader Professor Roy Robins-Browne	Microbiology and Immunology
Diabetic cardiomyopathy – an epidemic disease	Research Project Leader Professor Lea Delbridge	Anatomy and Physiology
Diana Stojanovski laboratory	Head of Laboratory Dr Diana Stojanovski	Biochemistry and Pharmacology
Discovering and characterizing new genes involved in innate immunity, tissue injury and fibrosis	Project Leader Professor Christine Wells	Anatomy and Physiology
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Research Project Leader Professor Matthew Watt	Anatomy and Physiology
Dodd laboratory: Metabolic Neuroscience	Head of Laboratory Dr Garron Dodd	Anatomy and Physiology
EMT regulators in intestinal and germline stem cells	Project Leader Professor Gary Hime	Anatomy and Physiology
Enterococcus faecium	Project Leader Professor Ben Howden	Microbiology and Immunology
Establishing the effect of glycine/serine metabolism on skeletal muscle cell growth	Research Project Leader Dr René Koopman	Anatomy and Physiology
Exercise-induced liver-muscle cross-talk and mitochondrial adaptations	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
Exploiting nanoparticles as vaccines	A/Prof Justine Mintern	Biochemistry and Pharmacology
Exploring new roles for the TGFβ signalling network as a key regulator of skeletal muscle in health and disease	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Factors that accelerate photoreceptor death: The role of purines	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
Fletcher laboratory: Visual neuroscience	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
Functional neuroanatomy of genitourinary vasculature	Project Leaders Professor Janet Keast / Dr Peregrine Osborne	Anatomy and Physiology
Furness laboratory: Digestive physiology and nutrition	Head of Laboratory Professor John Furness	Anatomy and Physiology
Gavin Reid laboratory	Head of Laboratory Professor Gavin E. Reid	Biochemistry and Pharmacology
Gebhardt laboratory: Adaptive immune responses to virus infections	Head of Laboratory Professor Thomas Gebhardt	Microbiology and Immunology
Genetics of blood brain barrier formation	Project Leader Professor Ben Hogan	Anatomy and Physiology
Glial cells as a source of progenitor cells in degenerative disease	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
Godfrey laboratory: The development and function of unconventional T cells	Head of Laboratory Professor Dale Godfrey	Microbiology and Immunology
Gregorevic laboratory: Muscle Research and Therapeutics	Head of Laboratory Associate Professor Paul Gregorevic	Anatomy and Physiology
Gunnersen laboratory: Neuron development and plasticity	Head of Laboratory Associate Professor Jenny Gunnersen	Anatomy and Physiology
Haque Laboratory	Head of Laboratory Associate Professor Ashraful Haque	Microbiology and Immunology
Harnessing local immunity to block the development of secondary bacterial pneumonia	Project Leader Dr Linda Wakim	Microbiology and Immunology
Heath laboratory: CD8 T lymphocytes, dendritic cells, self tolerance and immunity	Head of Laboratory Professor William (Bill) Heath	Microbiology and Immunology
Hime laboratory: Stem cell genetics and Drosophila models of human disease	Head of Laboratory Professor Gary Hime	Anatomy and Physiology
Hogan laboratory: Vascular Cell and Developmental Biology	Head of Laboratory Professor Ben Hogan	Anatomy and Physiology
How do dietary nutrients affect the ability of stem cells and stem cell-derived tumours to grow and divide?	Project Leader A/Professor Louise Cheng	Anatomy and Physiology
How do neural stem cells maintain quiescence?	Project Leader A/Professor Louise Cheng	Anatomy and Physiology
How do neurons maintain their specialised status?	Project Leader A/Professor Louise Cheng	Anatomy and Physiology
How do tumours compete for resources to grow?	Project Leader A/Professor Louise Cheng	Anatomy and Physiology
How does GM-CSF prevent brain damage after traumatic injury?	Head of Laboratory Dr Jenny Gunnersen Project Leader Dr Sandy Shultz	Anatomy and Physiology
How infection and trauma cause dendritic cell paralysis and lethal immunosuppression	Professor Jose Villadangos	Microbiology and Immunology
How is the immunological T cell memory generated?	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Howden laboratory: Molecular epidemiology, genomics and pathogenesis of antimicrobial resistant bacteria	Head of Laboratory \| Director of MDU Professor Ben Howden	Microbiology and Immunology
Human brain networks processing respiratory sensations	Project Leader Professor Stuart Mazzone	Anatomy and Physiology
Hypothalamic modulation of basal sympathetic activity	Research Project Leader Professor Andrew Allen	Anatomy and Physiology
Ian van Driel laboratory	Head of Laboratory Professor Ian van Driel	Biochemistry and Pharmacology
Identifying factors that improve gastrointestinal function in Duchenne's muscular dystrophy	Research Project Leader Professor Gordon Lynch	Anatomy and Physiology
Identifying the mechanisms of immune cell development in peripheral tissues	Project Leader Professor Laura Mackay	Microbiology and Immunology
Imaging effector and memory T cell responses in the skin following Herpes Simplex Virus-1 infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Imaging the priming of CD8 Killer T cell responses to Herpes Simplex Virus-1 skin infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Immunoregulatory functions of the MARCH family of ubiquitin ligases	Professor Jose Villadangos	Biochemistry and Pharmacology
Improved vaccines by targeting to dendritic cells	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Improving the diagnostic outcomes of patients with mitochondrial disease	Dr David Stroud	Biochemistry and Pharmacology
Influenza A virus PB1-F2 Protein: a putative virulence factor and initiator of inflammation	Project Leader Dr Julie McAuley	Microbiology and Immunology
Influenza and HIV vaccines and the importance of mucosal immunity	Project Leader Professor Stephen Kent	Microbiology and Immunology
Influenza–specific ADCC: Role in a universal flu vaccine?	Project Leader Professor Stephen Kent	Microbiology and Immunology
Innate immunity and neural injury	Head of Laboratory Associate Professor Peter Crack	Biochemistry and Pharmacology
Innate T cell recognition and development	Project Leader Dr Daniel Pellicci	Microbiology and Immunology
Innovative approaches to prepare synthetic, partially synthetic and natural product-based vaccines	Project Leader Professor David Jackson	Microbiology and Immunology
Insulin on the Brain	Research Project Leader Dr Garron Dodd	Anatomy and Physiology
Intraepithelial T cells in anti-viral immunity	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
Intravital imaging of T cell responses in the brain during cerebral malaria infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Investigating mechanisms of protein trafficking to human mitochondria	Dr Diana Stojanovski	Biochemistry and Pharmacology
Investigating the Dystrophin-Glycoprotein Complex to Protect Muscles from Wasting Conditions	Research Project Leader Professor Gordon Lynch	Anatomy and Physiology
Investigating the mechanism of action of the antiviral molecule, IFITM3	Project Leader Dr Linda Wakim	Microbiology and Immunology
Investigating the role of cachexia in the response to surgical tumour resection in mice	Research Project Leader Professor Gordon Lynch	Anatomy and Physiology
Investigation of HSV latency and reactivation	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
Is the “shed” form of Sez-6 proteins responsible for their synapse-promoting effects?	Head of Laboratory Dr Jenny Gunnersen Project Leader Dr Kathryn Munro	Anatomy and Physiology
Jackson laboratory: Synthetic vaccine design	Head of Laboratory Professor David Jackson	Microbiology and Immunology
Justine Mintern laboratory	Head of Laboratory A/Prof Justine Mintern	Biochemistry and Pharmacology
Kallies laboratory: Molecular immunology	Head of Laboratory Professor Axel Kallies	Microbiology and Immunology
Keast & Osborne laboratory: Neural and Bioelectronic Control of Pelvic Organs	Joint Heads of Laboratory Professor Janet Keast & Dr Peregrine Osborne	Anatomy and Physiology
Kedzierska laboratory: Immunity to pandemic and newly emerged influenza viruses	Head of Laboratory Associate Professor Katherine Kedzierska	Microbiology and Immunology
Kent laboratory: HIV vaccines; immune responses to HIV-1; immunotherapy	Head of Laboratory Professor Stephen Kent	Microbiology and Immunology
Klebsiella pneumoniae	Project Leader Professor Dick Strugnell	Microbiology and Immunology
Koopman laboratory: Clinical nutrition and muscle metabolism	Head of Laboratory Associate Professor René Koopman	Anatomy and Physiology
Kristin Brown laboratory	Head of Laboratory Dr Kristin Brown	Biochemistry and Pharmacology
Laura Edgington-Mitchell laboratory	Head of Research Group Dr Laura Edgington-Mitchell	Biochemistry and Pharmacology
Lawson laboratory: Transmissible neurodegeneration	Head of Laboratory Associate Professor Vicki Lawson	Microbiology and Immunology
Learning from skeletal muscles to develop new treatments for cancer	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Lipopeptide-based adjuvanting systems	Project Leader Professor David Jackson	Microbiology and Immunology
Live imaging of cellular signalling in vascular development and disease models	Project Leader Professor Ben Hogan	Anatomy and Physiology
Liz Hinde laboratory	Head of Research Group Dr Elizabeth Hinde	Biochemistry and Pharmacology
Lung Disease Research Laboratory	Head of Laboratory Professor Gary P Anderson	Biochemistry and Pharmacology
Lynch laboratory: Basic and clinical myology	Head of Laboratory Professor Gordon Lynch	Anatomy and Physiology
Mackay laboratory: Tissue-resident memory T cells; lymphocyte differentiation; peripheral immunity	Senior Lecturer & NHMRC Career Development Fellow, HHMI-Gates International Research Scholar Professor Laura Mackay	Microbiology and Immunology
Mackenzie laboratory: Intracellular virus replication and innate immunity	Head of Laboratory Professor Jason Mackenzie	Microbiology and Immunology
MAIT cells in homeostasis and microbial infections	Researchers Dr Zhenjun Chen, Dr Alexandra Corbett and Dr Sidonia Eckle	Microbiology and Immunology
Malaria and Tissue Resident Memory T cells (TRM) in the liver	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Manipulating immunity to fight infection and tumours	A/Prof Justine Mintern	Biochemistry and Pharmacology
Mapping the distribution of angiotensin receptors in the brain	Research Project Leader Professor Andrew Allen	Anatomy and Physiology
Mapping the proteome vulnerable to unfolding and aggregation under proteostasis stress	A/Prof Danny Hatters	Biochemistry and Pharmacology
Mature and developing synaptic transmission between defined classes of enteric neurons	Research Project Leader Dr Jaime Foong	Anatomy and Physiology
Mazzone laboratory: Respiratory Sensory Neuroscience	Head of Research Group Professor Stuart Mazzone	Anatomy and Physiology
McCluskey laboratory: Role of MAIT cells in health and disease	Head of Laboratory Redmond Barry Distinguished Professor James McCluskey	Microbiology and Immunology
McDevitt laboratory	Head of Laboratory Associate Professor Christopher McDevitt	Microbiology and Immunology
Mechanisms of diastolic heart failure	Research Project Leader Professor Lea Delbridge	Anatomy and Physiology
Mechanisms underlying early generation of human T cell memory	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Memory T cell responses in the lung during virus infection	Project Leader Dr Linda Wakim	Microbiology and Immunology
Metabolic reprogramming and chemotherapy resistance in triple-negative breast cancer	Project Leader Dr Kristin Brown	Biochemistry and Pharmacology
Metabolic reprogramming of skeletal muscle stem cells	Research Project Leader Professor Gordon Lynch	Anatomy and Physiology
Michael Parker laboratory	Head of Laboratory and Director, Bio21 Institute Professor Michael Parker	Biochemistry and Pharmacology
Mike Griffin laboratory	Head of Laboratory Dr Michael Griffin	Biochemistry and Pharmacology
Molecular and cellular analysis of mammalian ovary development and disease	Project Leader Associate Professor Dagmar Wilhelm	Anatomy and Physiology
Molecular mechanisms controlling lymphangiogenesis	Project Leader Professor Ben Hogan	Anatomy and Physiology
Molecular Mechanisms of Disease
Molecular mechanisms that contribute to skeletal pain	Head of Laboratory Associate Professor Jason Ivanusic	Anatomy and Physiology
Montgomery laboratory: Metabolic Tissue Cross-Talk	Head of Laboratory Dr Magdalene Montgomery	Anatomy and Physiology
MR1 – a molecular alarm system that detects pathogen metabolites	Professor Jose Villadangos	Microbiology and Immunology
Murray laboratory: Myelin biology	Head of Laboratory Associate Professor Simon Murray	Anatomy and Physiology
Muscle wasting in multiple system atrophy	Research Project Leader Professor Gordon Lynch	Anatomy and Physiology
Mycobacterium ulcerans	Project Leader Professor TIm Stinear	Microbiology and Immunology
Nanoparticle HIV vaccines	Project Leader Professor Stephen Kent	Microbiology and Immunology
Nanoparticle Modulation of Mast Cell Function	Project Leader Dr Graham Mackay	Biochemistry and Pharmacology
Neuroanatomy of human visceral systems	Professor Janet Keast	Anatomy and Physiology
Newton laboratory: Virulence strategies of intracellular bacterial pathogens	Head of Laboratory Dr Hayley Newton	Microbiology and Immunology
NK cell receptor biology	Project Leader Professor Andrew Brooks	Microbiology and Immunology
Non-classical MHC and Class 1-like molecules	Project Leader Professor Andrew Brooks	Microbiology and Immunology
Non-conventional T cells and HIV: role of NKT cells, MAIT cells, CD-1 restricted and gamma-delta T cells	Project Leader Professor Stephen Kent	Microbiology and Immunology
Norman Saunders laboratory	Head of Laboratory Professor Norman Saunders	Biochemistry and Pharmacology
Norovirus replication and innate immunity	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
Novel Mast Cell-Derived Mediators	Project Leader Dr Graham Mackay	Biochemistry and Pharmacology
Oxidative stress and neural injury	Head of Laboratory Associate Professor Peter Crack	Biochemistry and Pharmacology
Pain management using ultrasound-guided local anaesthetic techniques	Head of Laboratory Associate Professor Jason Ivanusic	Anatomy and Physiology
Parker laboratory: Metabolic Proteomics & Signal Transduction	Head of Laboratory Dr Benjamin Parker	Anatomy and Physiology
Passive antibody immunity for use in combination microbicides	Project Leader Professor Damian Purcell	Microbiology and Immunology
Paul Gleeson laboratory	Head of Laboratory Professor Paul Gleeson	Biochemistry and Pharmacology
Paul Gooley laboratory	Head of Laboratory Professor Paul Gooley	Biochemistry and Pharmacology
Personalising treatments for genetic diseases	Dr David Ascher	Biochemistry and Pharmacology
Peter Crack laboratory	Head of Laboratory Associate Professor Peter Crack	Biochemistry and Pharmacology
Post-translational control of cell fate decisions	Project Leader Associate Professor Dagmar Wilhelm	Anatomy and Physiology
Precursor exhausted T cells in chronic infection and tumors	Project Leader Professor Axel Kallies	Microbiology and Immunology
Prognostic biomarker and therapeutic target discovery in stroke	Project Leader Dr Jonathon Mangum	Biochemistry and Pharmacology
Project 1. How do CD4+ T cells preserve memories during malaria?	Head of Laboratory Associate Professor Ashraful Haque	Microbiology and Immunology
Project 1. Should we worry about prion associated heart disease?	Head of Laboratory Associate Professor Vicki Lawson	Microbiology and Immunology
Project 2. CD4+ T cells in acute Graft-versus-Host Disease	Head of Laboratory Associate Professor Ashraful Haque	Microbiology and Immunology
Project 2. COVID-19 associated brain injury and inflammation	Head of Laboratory Associate Professor Vicki Lawson	Microbiology and Immunology
Project 3. Do malaria parasites sense and respond to the host during infection?	Head of Laboratory Associate Professor Ashraful Haque	Microbiology and Immunology
Purcell laboratory: Viral RNA elements, regulation of HIV replication, HIV antibody vaccine	Head of Laboratory Professor Damian Purcell	Microbiology and Immunology
Reading laboratory: Innate immune detection and response to respiratory virus infections	Head of Laboratory Associate Professor Patrick Reading	Microbiology and Immunology
Regulation of Mast Cell Activation	Project Leader Dr Graham Mackay	Biochemistry and Pharmacology
Resident memory T cells (Trm)	Project Leader Professor Axel Kallies	Microbiology and Immunology
Risk genes for neuropsychiatric disorders	Project Leader Dr Mike Clark	Anatomy and Physiology
RNA mediated control of HIV-1 gene expression	Project Leader Professor Damian Purcell	Microbiology and Immunology
Robb De Iongh Laboratory: Ocular Development Laboratory	Head of Laboratory Associate Professor Robb de Iongh	Anatomy and Physiology
Robins-Browne laboratory: Medical bacteriology, pathogenesis, bacterial genetics, therapeutics	Head of Laboratory Professor Roy Robins-Browne	Microbiology and Immunology
Robyn Brown laboratory	Head of Laboratory Dr Robyn M Brown	Biochemistry and Pharmacology
Role of cellular lipids during Flavivirus replication	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
Role of innate signals in inducing protective T cell immunity	Project Leader Professor Sammy Bedoui	Microbiology and Immunology
Role of long noncoding RNAs in neurological disorders	Project Leader Dr Mike Clark	Anatomy and Physiology
Salmonella Typhimurium	Project Leader Professor Dick Strugnell	Microbiology and Immunology
Self-tolerance: Interactions between thymic stroma and dendritic cells	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Sex in human malaria parasites	Dr Matthew Dixon	Biochemistry and Pharmacology
Sex, adiposity and cardiac vulnerability	Research Project Leader Professor Lea Delbridge	Anatomy and Physiology
Sex-specific regulation of adipose tissue immune cells	Project Leader Professor Axel Kallies	Microbiology and Immunology
Shabih Shakeel laboratory	Lab Head & Principal Research Fellow Dr Shabih Shakeel	Biochemistry and Pharmacology
Skeletal muscle signal transduction related to exercise, metabolic disease and human health	Research Project Leader Dr Benjamin Parker	Anatomy and Physiology
Small molecules for BIG targets- Targeting protein-protein interactions with fragments	Dr David Ascher	Biochemistry and Pharmacology
Smith laboratory: Cardiac Genetics	Head of Laboratory Associate Professor Kelly Smith	Anatomy and Physiology
Soluble barriers to influenza virus infection	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
Staphylococcus aureus & Enterococcus faecium	Project Leader Professor Tim Stinear	Microbiology and Immunology
Staphylococcus aureus and Staphylococcus epidermidis	Project Leader Professor Ben Howden	Microbiology and Immunology
Stroke	Head of Laboratory Associate Professor Peter Crack	Biochemistry and Pharmacology
Structural Biology of Cancer	Professor Michael Parker	Biochemistry and Pharmacology
Structural Biology of Infection	Professor Michael Parker	Biochemistry and Pharmacology
Structural Neurobiology	Professor Michael Parker	Biochemistry and Pharmacology
Structure and function of bacterial "cytomotive" filaments	Project Leader Dr Debnath Ghosal	Biochemistry and Pharmacology
Strugnell laboratory: Bacterial pathogenesis and host responses	Head of Laboratory Professor Dick Strugnell	Microbiology and Immunology
Stuart Ralph laboratory	Head of Laboratory Dr Stuart Ralph	Biochemistry and Pharmacology
Systems genetics of muscle metabolism	Research Project Leader Dr Benjamin Parker	Anatomy and Physiology
T cells in peripheral immunity	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
Tackling drug resistance	Dr David Ascher	Biochemistry and Pharmacology
The amyloidogenic protease inhibitor Cystatin C in health and disease	Prof Jose Villadangos	Biochemistry and Pharmacology
The Bonn and Melbourne Research and Graduate School	Melbourne Coordinator Dr Marie Greyer
The Enteric Neural Circuitry Activated During Bacterial-toxin Induced Diarrhoea	Research Project Leader Dr Jaime Foong	Anatomy and Physiology
The heart as a central player in tissue cross-talk	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
The innate immune system in the respiratory tract	Project Leader Professor David Jackson	Microbiology and Immunology
The mechanisms of viral escape in murine and human influenza infection	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
The role of CD4+ T cells in viral infections	Project Leader Professor Andrew Brooks	Microbiology and Immunology
The Role of enteric neurons in gastrointestinal symptoms associated with Autism Spectrum disorders	Research Project Leader Dr Elisa Hill-Yardin	Anatomy and Physiology
The role of glia in inner retinal changes during retinal degeneration	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
The role of glial cells in retinal vascular disease	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
The role of innate immune cells in protection and pathology during influenza virus infection	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
The role of microglia in age-related macular degeneration	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
The role of mitochondria in Coxiella burnetii infection	Dr Diana Stojanovski	Biochemistry and Pharmacology
The role of protein modifications on muscle development	Research Project Leader Dr Benjamin Parker	Anatomy and Physiology
The role of resident memory T cells in barrier immunity and autoimmune disease	Project Leader Professor Laura Mackay	Microbiology and Immunology
The role of the prorenin receptor in male and female fertility	Project Leader Associate Professor Dagmar Wilhelm	Anatomy and Physiology
The roles of metal ions in host-pathogen interaction	Research Project Leader Associate Professor Christopher McDevitt	Microbiology and Immunology
Therapeutic potential of skeletal muscle plasticity and slow muscle programming for muscular dystrophy	Research Project Leader Professor Gordon Lynch	Anatomy and Physiology
Tissue communication in non-alcoholic fatty liver disease (NALFD) and liver fibrosis	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
Tracking phenotypically and functionally distinct T cell subsets via T cell repertoire diversity	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Transcriptional profiling of sensory neurons	Project Leader Professor Stuart Mazzone	Anatomy and Physiology
Transcriptional regulation of cancer cell metabolism	Project Leader Dr Kristin Brown	Biochemistry and Pharmacology
Transcriptional reprogramming of metabolism in liver cancer	Project Leader Dr Andrew Cox	Biochemistry and Pharmacology
Traumatic brain injury	Head of Laboratory Associate Professor Peter Crack	Biochemistry and Pharmacology
Treating the person not the disease	Dr David Ascher	Biochemistry and Pharmacology
Uncovering the interplay between innate immunity and the blood brain barrier in disorders of the CNS	Project Leader Professor Christine Wells	Anatomy and Physiology
Understanding how Anthrax toxins function	Associate Professor Isabelle Rouiller	Biochemistry and Pharmacology
Understanding how membrane-less organelles form with optogenetic tools	A/Prof Danny Hatters	Biochemistry and Pharmacology
Understanding how metal ions traverse bacterial cell membranes	Research Project Leader Associate Professor Christopher McDevitt	Microbiology and Immunology
Understanding how the ATPase p97 functions at molecular level	Associate Professor Isabelle Rouiller	Biochemistry and Pharmacology
Understanding immune dysfunction in acute myeloid leukemia	A/Prof Justine Mintern	Biochemistry and Pharmacology
Understanding metabolic cross-talk in health and disease - Focus on type 2 diabetes and fatty liver	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
Understanding the aetiology of hypertension	Research Project Leader Professor Andrew Allen	Anatomy and Physiology
Understanding the assembly of mitochondrial machines	Dr David Stroud	Biochemistry and Pharmacology
Understanding the interaction between microbiota and T cell immunity	Project Leader Professor Sammy Bedoui	Microbiology and Immunology
Understanding the Molecular Consequences of Mutations	Dr David Ascher David Ascher	Biochemistry and Pharmacology
Understanding the regulation of tissue-resident memory T cell development	Project Leader Professor Laura Mackay	Microbiology and Immunology
Understanding the role of angiotensin in the rostral ventrolateral medulla	Research Project Leader Professor Andrew Allen	Anatomy and Physiology
Understanding ‘universal’ influenza-specific CD8+ T cell responses	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Unravelling the mysteries of E3 ubiquitin ligase in regulating skeletal muscle size and function	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Using the immune system to kill tumours	A/Prof Justine Mintern	Biochemistry and Pharmacology
Vaccination against liver-stage Plasmodium for malaria prevention	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Villadangos laboratory	Head of Laboratory Professor Jose Villadangos	Biochemistry and Pharmacology
Viral interactions with the innate immune system	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
Visualization and formation West Nile Virus replication complexes	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
Wakim laboratory: Antiviral molecules, mucosal immunology, influenza virus, tissue resident memory T cells	Head of Laboratory Dr Linda Wakim	Microbiology and Immunology
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Anatomy and Physiology
West Nile Virus replication and cellular stress responses	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
What is the function of Sez6L2 in the forebrain?	Head of Laboratory Dr Jenny Gunnersen Project Leader Dr Kathryn Munro	Anatomy and Physiology
Wilhelm laboratory: Gonad Development and Fertility	Head of Laboratory Associate Professor Dagmar Wilhelm	Anatomy and Physiology
“Clock-off time” for inflammation and remodelling in chronic inflammatory diseases: casein kinase inhibitors	Professor Alastair Stewart	Pharmacology and Therapeutics

264

Biomedical Neuroscience

Groups / Projects	Research Lead	Dept / Centre
Understanding the plasticity of skeletal muscle in health and disease	Research Project Leader Professor Gordon Lynch	Anatomy and Physiology
A gut feeling about new therapies for glioma	Joint Project Leaders Dr Lincon Stamp & Dr Marlene Hao	Anatomy and Physiology
Allen laboratory: Central cardiovascular regulation	Head of Laboratory Professor Andrew Allen	Anatomy and Physiology
Angiotensin and chemoreceptor function	Research Project Leader Professor Andrew Allen	Anatomy and Physiology
Applications of Nanopore sequencing	Project Leader Dr Mike Clark	Anatomy and Physiology
Aptamers: developing a novel technology for hormone measurement	Project Leader/Supervisor Dr Linda Fothergill, Professor John Furness	Anatomy and Physiology
Autologous stem cell therapies in Australia	Project Leader Professor Megan Munsie	Anatomy and Physiology
Biomedical Neuroscience
Blood Atlas: Understanding cell state and differentiation using genomics data from blood cells	Project Leader Professor Christine Wells	Anatomy and Physiology
Bornstein laboratory: Enteric neuroscience	Head of Laboratory Professor Joel C Bornstein	Anatomy and Physiology
Brain networks processing respiratory sensations	Project Leader Professor Stuart Mazzone	Anatomy and Physiology
Brain-gut axis: Neural pathways controlling the stomach and their relevance for treatment of gastroparesis	Project Leader/Supervisor Professor John Furness, Dr Martin Stebbing	Anatomy and Physiology
Building a urogenital nervous system connectome	Project Leaders Professor Janet Keast / Dr Peregrine Osborne	Anatomy and Physiology
Cell state and cell fate: Systems biology approaches to understanding cell identity	Project Leader Professor Christine Wells	Anatomy and Physiology
Cheng laboratory: Stem cell and organ size control regulation	Head of Laboratory Associate Professor Louise Cheng	Anatomy and Physiology
Clark laboratory: Transcriptomics and Neurogenetics	Head of Laboratory Dr Mike Clark	Anatomy and Physiology
Contemplating stem cells in society	Project Leader Dr Claire Tanner	Anatomy and Physiology
Peter Crouch laboratory	Head of Laboratory Dr Peter Crouch	Biochemistry and Pharmacology
Daniel Hoyer laboratory	Head of Laboratory Professor Daniel Hoyer	Biochemistry and Pharmacology
Danny Hatters laboratory	Head of Laboratory Professor Danny Hatters	Biochemistry and Pharmacology
Defining new roles for the Hippo signalling pathway in skeletal muscle	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Designing new optogenetic tools for biomedical research	A/Prof Danny Hatters	Biochemistry and Pharmacology
Developing innovative animal and cell culture models to study and treat muscular dystrophies	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Development of new PET scans and blood tests for the early diagnosis of neurodegenerative	Professor Christopher Rowe	Florey Department of Neuroscience and Mental Health
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Research Project Leader Professor Matthew Watt	Anatomy and Physiology
Exercise-induced liver-muscle cross-talk and mitochondrial adaptations	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
Exploring new roles for the TGFβ signalling network as a key regulator of skeletal muscle in health and disease	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Factors that accelerate photoreceptor death: The role of purines	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
Fletcher laboratory: Visual neuroscience	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
Fogg laboratory: Surgical Anatomy	Head of Laboratory Associate Professor Quentin Fogg	Anatomy and Physiology
Food entertainment of circadian rhythms	Project Supervisor Dr Lalita Oparija	Anatomy and Physiology
Functional neuroanatomy of genitourinary vasculature	Project Leaders Professor Janet Keast / Dr Peregrine Osborne	Anatomy and Physiology
Furness laboratory: Digestive physiology and nutrition	Head of Laboratory Professor John Furness	Anatomy and Physiology
Genetics of blood brain barrier formation	Project Leader Professor Ben Hogan	Anatomy and Physiology
Glial cells as a source of progenitor cells in degenerative disease	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
Gregorevic laboratory: Muscle Research and Therapeutics	Head of Laboratory Associate Professor Paul Gregorevic	Anatomy and Physiology
Growth factors and peptide mimetics	Project Leader Dr Susan Northfield	Biochemistry and Pharmacology
Gunnersen laboratory: Neuron development and plasticity	Head of Laboratory Associate Professor Jenny Gunnersen	Anatomy and Physiology
Hogan laboratory: Vascular Cell and Developmental Biology	Head of Laboratory Professor Ben Hogan	Anatomy and Physiology
How do dietary nutrients affect the ability of stem cells and stem cell-derived tumours to grow and divide?	Project Leader A/Professor Louise Cheng	Anatomy and Physiology
How do neural stem cells maintain quiescence?	Project Leader A/Professor Louise Cheng	Anatomy and Physiology
How do neurons maintain their specialised status?	Project Leader A/Professor Louise Cheng	Anatomy and Physiology
How do tumours compete for resources to grow?	Project Leader A/Professor Louise Cheng	Anatomy and Physiology
How does GM-CSF prevent brain damage after traumatic injury?	Head of Laboratory Dr Jenny Gunnersen Project Leader Dr Sandy Shultz	Anatomy and Physiology
Human brain networks processing respiratory sensations	Project Leader Professor Stuart Mazzone	Anatomy and Physiology
Hypothalamic modulation of basal sympathetic activity	Research Project Leader Professor Andrew Allen	Anatomy and Physiology
Identifying factors that improve gastrointestinal function in Duchenne's muscular dystrophy	Research Project Leader Professor Gordon Lynch	Anatomy and Physiology
Innate immunity and neural injury	Head of Laboratory Associate Professor Peter Crack	Biochemistry and Pharmacology
Insulin on the Brain	Research Project Leader Dr Garron Dodd	Anatomy and Physiology
Is the “shed” form of Sez-6 proteins responsible for their synapse-promoting effects?	Head of Laboratory Dr Jenny Gunnersen Project Leader Dr Kathryn Munro	Anatomy and Physiology
Isabelle Rouiller laboratory	Associate Professor Isabelle Rouiller	Biochemistry and Pharmacology
Keast & Osborne laboratory: Neural and Bioelectronic Control of Pelvic Organs	Joint Heads of Laboratory Professor Janet Keast & Dr Peregrine Osborne	Anatomy and Physiology
Lawson laboratory: Transmissible neurodegeneration	Head of Laboratory Associate Professor Vicki Lawson	Microbiology and Immunology
Learning from skeletal muscles to develop new treatments for cancer	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Live imaging of cellular signalling in vascular development and disease models	Project Leader Professor Ben Hogan	Anatomy and Physiology
Mapping the distribution of angiotensin receptors in the brain	Research Project Leader Professor Andrew Allen	Anatomy and Physiology
Mapping the proteome vulnerable to unfolding and aggregation under proteostasis stress	A/Prof Danny Hatters	Biochemistry and Pharmacology
Mature and developing synaptic transmission between defined classes of enteric neurons	Research Project Leader Dr Jaime Foong	Anatomy and Physiology
Mazzone laboratory: Respiratory Sensory Neuroscience	Head of Research Group Professor Stuart Mazzone	Anatomy and Physiology
Mike Griffin laboratory	Head of Laboratory Dr Michael Griffin	Biochemistry and Pharmacology
Molecular mechanisms controlling lymphangiogenesis	Project Leader Professor Ben Hogan	Anatomy and Physiology
Molecular mechanisms that contribute to skeletal pain	Head of Laboratory Associate Professor Jason Ivanusic	Anatomy and Physiology
Montgomery laboratory: Metabolic Tissue Cross-Talk	Head of Laboratory Dr Magdalene Montgomery	Anatomy and Physiology
Mueller laboratory: Visualising the immune system in action	Head of Laboratory Professor Scott Mueller	Microbiology and Immunology
Murray laboratory: Myelin biology	Head of Laboratory Associate Professor Simon Murray	Anatomy and Physiology
Muscle wasting in multiple system atrophy	Research Project Leader Professor Gordon Lynch	Anatomy and Physiology
Neuro-immune interactions: Nerve pathways that control inflammation in the intestine	Project Leader/Supervisor Dr Martin Stebbing	Anatomy and Physiology
Neuroanatomy of human visceral systems	Professor Janet Keast	Anatomy and Physiology
Norman Saunders laboratory	Head of Laboratory Professor Norman Saunders	Biochemistry and Pharmacology
Novel heteromeric receptors in gut control: ghrelin receptors and dopamine receptors working together	Project Leader/Supervisor Professor John Furness & Dr Ruslan Pustovit	Anatomy and Physiology
Novel technique to determine the pKA of clonidine at prejunctional α2-adrenoceptors in sympathetic transmission	Project Leader Professor James Angus	Biochemistry and Pharmacology
Oxidative stress and neural injury	Head of Laboratory Associate Professor Peter Crack	Biochemistry and Pharmacology
Pain management using ultrasound-guided local anaesthetic techniques	Head of Laboratory Associate Professor Jason Ivanusic	Anatomy and Physiology
Patient voices: An analysis of patients’ information-based priorities and needs	Project Leader Professor Megan Munsie	Anatomy and Physiology
Paul Gooley laboratory	Head of Laboratory Professor Paul Gooley	Biochemistry and Pharmacology
Peter Crack laboratory	Head of Laboratory Associate Professor Peter Crack	Biochemistry and Pharmacology
Prognostic biomarker and therapeutic target discovery in stroke	Project Leader Dr Jonathon Mangum	Biochemistry and Pharmacology
Project 1. Should we worry about prion associated heart disease?	Head of Laboratory Associate Professor Vicki Lawson	Microbiology and Immunology
Project 2. COVID-19 associated brain injury and inflammation	Head of Laboratory Associate Professor Vicki Lawson	Microbiology and Immunology
Protecting the gut from the damaging consequences of obesity	Project Leader/Supervisor Dr Rachel McQuade	Anatomy and Physiology
Relaxin family peptide hormones	Project Leader Associate Professor Tony Hughes	Biochemistry and Pharmacology
Risk genes for neuropsychiatric disorders	Project Leader Dr Mike Clark	Anatomy and Physiology
Robb De Iongh Laboratory: Ocular Development Laboratory	Head of Laboratory Associate Professor Robb de Iongh	Anatomy and Physiology
Role of long noncoding RNAs in neurological disorders	Project Leader Dr Mike Clark	Anatomy and Physiology
Stamp & Hao laboratory: Development of the enteric nervous system	Joint Heads of Laboratory Dr Lincon Stamp & Dr Marlene Hao	Anatomy and Physiology
Stroke	Head of Laboratory Associate Professor Peter Crack	Biochemistry and Pharmacology
Structural Neurobiology	Professor Michael Parker	Biochemistry and Pharmacology
The amyloidogenic protease inhibitor Cystatin C in health and disease	Prof Jose Villadangos	Biochemistry and Pharmacology
The Enteric Neural Circuitry Activated During Bacterial-toxin Induced Diarrhoea	Research Project Leader Dr Jaime Foong	Anatomy and Physiology
The gastrointestinal complications of Parkinson's Disease	Project Leader/Supervisor Dr Rachel McQuade	Anatomy and Physiology
The heart as a central player in tissue cross-talk	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
The link between cardiovascular disease and neurodegeneration – focus on Alzheimer’s disease	Project Leader Associate Professor Christine Wright	Biochemistry and Pharmacology
The Role of enteric neurons in gastrointestinal symptoms associated with Autism Spectrum disorders	Research Project Leader Dr Elisa Hill-Yardin	Anatomy and Physiology
The role of glia in inner retinal changes during retinal degeneration	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
The role of glial cells in retinal vascular disease	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
The role of microglia in age-related macular degeneration	Head of Laboratory Professor Erica Fletcher	Anatomy and Physiology
The Stemformatics Stem Cell Atlas	Project Leader Professor Christine Wells	Anatomy and Physiology
Tissue communication in non-alcoholic fatty liver disease (NALFD) and liver fibrosis	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
Tony Hughes & Susan Northfield laboratory	Joint Heads of Laboratory Associate Professor Tony Hughes & Dr Susan Northfield	Biochemistry and Pharmacology
Transcriptional profiling of sensory neurons	Project Leader Professor Stuart Mazzone	Anatomy and Physiology
Traumatic brain injury	Head of Laboratory Associate Professor Peter Crack	Biochemistry and Pharmacology
Understanding how membrane-less organelles form with optogenetic tools	A/Prof Danny Hatters	Biochemistry and Pharmacology
Understanding how the ATPase p97 functions at molecular level	Associate Professor Isabelle Rouiller	Biochemistry and Pharmacology
Understanding metabolic cross-talk in health and disease - Focus on type 2 diabetes and fatty liver	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
Understanding the aetiology of hypertension	Research Project Leader Professor Andrew Allen	Anatomy and Physiology
Understanding the role of angiotensin in the rostral ventrolateral medulla	Research Project Leader Professor Andrew Allen	Anatomy and Physiology
Unravelling the mysteries of E3 ubiquitin ligase in regulating skeletal muscle size and function	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Anatomy and Physiology
What is the function of Sez6L2 in the forebrain?	Head of Laboratory Dr Jenny Gunnersen Project Leader Dr Kathryn Munro	Anatomy and Physiology
Wilkinson-Berka laboratory: Retinal vascular biology and inflammation	Head of Laboratory Professor Jennifer Wilkinson-Berka	Anatomy and Physiology
Yao laboratory: Cardiovascular Neuroscience	Head of Laboratory Dr Song Yao	Anatomy and Physiology

111

Stem Cells

Groups / Projects	Research Lead	Dept / Centre
A gut feeling about new therapies for glioma	Joint Project Leaders Dr Lincon Stamp & Dr Marlene Hao	Anatomy and Physiology
Analysing genetic roles of RNA-binding proteins and alternative splicing in Drosophila stem cells	Project Leader Professor Gary Hime	Anatomy and Physiology
Autologous stem cell therapies in Australia	Project Leader Professor Megan Munsie	Anatomy and Physiology
Blood Atlas: Understanding cell state and differentiation using genomics data from blood cells	Project Leader Professor Christine Wells	Anatomy and Physiology
Cell state and cell fate: Systems biology approaches to understanding cell identity	Project Leader Professor Christine Wells	Anatomy and Physiology
Cellular trafficking and male fertility	Project Leader Professor Gary Hime	Anatomy and Physiology
Cheng laboratory: Stem cell and organ size control regulation	Head of Laboratory Associate Professor Louise Cheng	Anatomy and Physiology
Clark laboratory: Transcriptomics and Neurogenetics	Head of Laboratory Dr Mike Clark	Anatomy and Physiology
Contemplating stem cells in society	Project Leader Dr Claire Tanner	Anatomy and Physiology
Eckersley-Maslin laboratory: Stem cell and cancer epigenetics	Head of Laboratory Dr Melanie Eckersley-Maslin	Anatomy and Physiology
EMT regulators in intestinal and germline stem cells	Project Leader Professor Gary Hime	Anatomy and Physiology
Functional genomic screens for cardiovascular drug discovery	Research Project Leader Dr Enzo Porrello	Anatomy and Physiology
Hime laboratory: Stem cell genetics and Drosophila models of human disease	Head of Laboratory Professor Gary Hime	Anatomy and Physiology
Investigating the Dystrophin-Glycoprotein Complex to Protect Muscles from Wasting Conditions	Research Project Leader Professor Gordon Lynch	Anatomy and Physiology
Investigating the role of cachexia in the response to surgical tumour resection in mice	Research Project Leader Professor Gordon Lynch	Anatomy and Physiology
Lynch laboratory: Basic and clinical myology	Head of Laboratory Professor Gordon Lynch	Anatomy and Physiology
Metabolic reprogramming of skeletal muscle stem cells	Research Project Leader Professor Gordon Lynch	Anatomy and Physiology
Modeling human heart development using human cardiac organoids	Research Project Leader Dr Enzo Porrello	Anatomy and Physiology
Molecular and cellular analysis of mammalian ovary development and disease	Project Leader Associate Professor Dagmar Wilhelm	Anatomy and Physiology
Munsie laboratory: Ethical, legal and social implications of stem cell research	Head of Laboratory Professor Megan Munsie	Anatomy and Physiology
Novel regulators of germline stem cells	Project Leader Professor Gary HIme	Anatomy and Physiology
Patient voices: An analysis of patients’ information-based priorities and needs	Project Leader Professor Megan Munsie	Anatomy and Physiology
Porrello laboratory: Cardiac Regeneration	Head of Laboratory Enzo Porrello	Anatomy and Physiology
Post-natal control of cardiac gene regulatory networks	Research Project Leader Dr Enzo Porrello	Anatomy and Physiology
Risk genes for neuropsychiatric disorders	Project Leader Dr Mike Clark	Anatomy and Physiology
Stamp & Hao laboratory: Development of the enteric nervous system	Joint Heads of Laboratory Dr Lincon Stamp & Dr Marlene Hao	Anatomy and Physiology
Stem Cells
The Stemformatics Stem Cell Atlas	Project Leader Professor Christine Wells	Anatomy and Physiology
Transcriptional regulation of intestinal organoid differentiation	Project Leader Professor Gary Hime	Anatomy and Physiology
Wells laboratory: Stem cell systems	Head of Laboratory Professor Christine Wells	Anatomy and Physiology

Systems Biology

Groups / Projects	Research Lead	Dept / Centre
Application of genomics to public health and clinical microbiology	Project Leader Professor Ben Howden	Microbiology and Immunology
Applications of Nanopore sequencing	Project Leader Dr Mike Clark	Anatomy and Physiology
Australian Venom Research Unit		Biochemistry and Pharmacology
Blood Atlas: Understanding cell state and differentiation using genomics data from blood cells	Project Leader Professor Christine Wells	Anatomy and Physiology
Cell state and cell fate: Systems biology approaches to understanding cell identity	Project Leader Professor Christine Wells	Anatomy and Physiology
Clinical Proteomics	Project Leader Dr Jonathon Mangum	Biochemistry and Pharmacology
Danny Hatters laboratory	Head of Laboratory Professor Danny Hatters	Biochemistry and Pharmacology
David Stroud laboratory	Head of Research Group Dr David Stroud	Biochemistry and Pharmacology
Delbridge laboratory: Cardiac phenomics	Head of Laboratory Professor Lea Delbridge	Anatomy and Physiology
Developing a novel class of therapeutics for muscle wasting and frailty	Research Project Leader Dr Benjamin Parker	Anatomy and Physiology
Diabetic cardiomyopathy – an epidemic disease	Research Project Leader Professor Lea Delbridge	Anatomy and Physiology
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Research Project Leader Professor Matthew Watt	Anatomy and Physiology
Enterococcus faecium	Project Leader Professor Ben Howden	Microbiology and Immunology
Exercise-induced liver-muscle cross-talk and mitochondrial adaptations	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
Functional neuroanatomy of genitourinary vasculature	Project Leaders Professor Janet Keast / Dr Peregrine Osborne	Anatomy and Physiology
Harrap laboratory: Genetic physiology	Head of Laboratory Professor Stephen Harrap	Anatomy and Physiology
How do dietary nutrients affect the ability of stem cells and stem cell-derived tumours to grow and divide?	Project Leader A/Professor Louise Cheng	Anatomy and Physiology
How do neural stem cells maintain quiescence?	Project Leader A/Professor Louise Cheng	Anatomy and Physiology
How do neurons maintain their specialised status?	Project Leader A/Professor Louise Cheng	Anatomy and Physiology
How do tumours compete for resources to grow?	Project Leader A/Professor Louise Cheng	Anatomy and Physiology
Howden laboratory: Molecular epidemiology, genomics and pathogenesis of antimicrobial resistant bacteria	Head of Laboratory \| Director of MDU Professor Ben Howden	Microbiology and Immunology
Improving the diagnostic outcomes of patients with mitochondrial disease	Dr David Stroud	Biochemistry and Pharmacology
Investigating mechanisms of protein trafficking to human mitochondria	Dr Diana Stojanovski	Biochemistry and Pharmacology
Malcolm McConville laboratory	Head of Laboratory Professor Malcolm McConville	Biochemistry and Pharmacology
Mechanisms of diastolic heart failure	Research Project Leader Professor Lea Delbridge	Anatomy and Physiology
Molecular mechanisms that contribute to skeletal pain	Head of Laboratory Associate Professor Jason Ivanusic	Anatomy and Physiology
Montgomery laboratory: Metabolic Tissue Cross-Talk	Head of Laboratory Dr Magdalene Montgomery	Anatomy and Physiology
Mycobacterium ulcerans	Project Leader Professor TIm Stinear	Microbiology and Immunology
Pain management using ultrasound-guided local anaesthetic techniques	Head of Laboratory Associate Professor Jason Ivanusic	Anatomy and Physiology
Parker laboratory: Metabolic Proteomics & Signal Transduction	Head of Laboratory Dr Benjamin Parker	Anatomy and Physiology
Risk genes for neuropsychiatric disorders	Project Leader Dr Mike Clark	Anatomy and Physiology
Robyn Brown laboratory	Head of Laboratory Dr Robyn M Brown	Biochemistry and Pharmacology
Role of long noncoding RNAs in neurological disorders	Project Leader Dr Mike Clark	Anatomy and Physiology
Scott Laboratory: Microbial glycoproteomics and host pathogen interactions	Head of Laboratory Dr Nichollas Scott	Microbiology and Immunology
Sex, adiposity and cardiac vulnerability	Research Project Leader Professor Lea Delbridge	Anatomy and Physiology
Skeletal muscle signal transduction related to exercise, metabolic disease and human health	Research Project Leader Dr Benjamin Parker	Anatomy and Physiology
Small molecules for BIG targets- Targeting protein-protein interactions with fragments	Dr David Ascher	Biochemistry and Pharmacology
Staphylococcus aureus & Enterococcus faecium	Project Leader Professor Tim Stinear	Microbiology and Immunology
Staphylococcus aureus and Staphylococcus epidermidis	Project Leader Professor Ben Howden	Microbiology and Immunology
Stinear laboratory: Bacterial pathogenomics	Head of Laboratory Professor Tim Stinear	Microbiology and Immunology
Systems Biology
Systems genetics of muscle metabolism	Research Project Leader Dr Benjamin Parker	Anatomy and Physiology
The Bonn and Melbourne Research and Graduate School	Melbourne Coordinator Dr Marie Greyer
The Cardiovascular Pharmacology of Snake Venoms From Papua New Guinea and Australia	Project Leader Associate Professor Christine Wright	Biochemistry and Pharmacology
The heart as a central player in tissue cross-talk	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
The role of protein modifications on muscle development	Research Project Leader Dr Benjamin Parker	Anatomy and Physiology
The Stemformatics Stem Cell Atlas	Project Leader Professor Christine Wells	Anatomy and Physiology
The Treatment of Papuan Taipan Envenoming in Papua New Guinea	Project Leader Dr David Williams	Biochemistry and Pharmacology
Tissue communication in non-alcoholic fatty liver disease (NALFD) and liver fibrosis	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
Treating the person not the disease	Dr David Ascher	Biochemistry and Pharmacology
Understanding metabolic cross-talk in health and disease - Focus on type 2 diabetes and fatty liver	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
Understanding the assembly of mitochondrial machines	Dr David Stroud	Biochemistry and Pharmacology
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Anatomy and Physiology
Wells laboratory: Stem cell systems	Head of Laboratory Professor Christine Wells	Anatomy and Physiology

Therapeutics & Translation

Groups / Projects	Research Lead	Dept / Centre
A universal vaccine against influenza A	Project Leader Professor David Jackson	Microbiology and Immunology
Alastair Stewart laboratory	Head of Laboratory Professor Alastair Stewart	Biochemistry and Pharmacology
Australian bite and sting trends: Australian Venomous Injury Project (AVIP)	Project Leader Dr Ronelle Welton	Biochemistry and Pharmacology
Australian Venom Research Unit		Biochemistry and Pharmacology
Autologous stem cell therapies in Australia	Project Leader Professor Megan Munsie	Anatomy and Physiology
Biolpolymer-based vaccine delivery systems	Project Leader Professor David Jackson	Microbiology and Immunology
Characterising the pathways responsible for ICU-acquired weakness	Research Project Leader Dr René Koopman	Anatomy and Physiology
Christine Wright laboratory	Head of Laboratory Associate Professor Christine E Wright	Biochemistry and Pharmacology
Contemplating stem cells in society	Project Leader Dr Claire Tanner	Anatomy and Physiology
Daniel Hoyer laboratory	Head of Laboratory Professor Daniel Hoyer	Biochemistry and Pharmacology
David Ascher laboratory	Head of Laboratory Dr David Ascher	Biochemistry and Pharmacology
Defining new roles for the Hippo signalling pathway in skeletal muscle	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Developing innovative animal and cell culture models to study and treat muscular dystrophies	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Development of a self-adjuvanting vaccine for enterotoxigenic Escherichia coli (ETEC)	Project Leader Professor David Jackson	Microbiology and Immunology
Development of Novel antimalarial drugs	Professor Leann Tilley	Biochemistry and Pharmacology
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Research Project Leader Professor Matthew Watt	Anatomy and Physiology
Dolcetti Laboratory: Clinical and Translational Immunotherapy	Head of Laboratory Professor Riccardo Dolcetti	Microbiology and Immunology
Elena Schneider-Futschik laboratory	Head of Laboratory Dr Elena Schneider-Futschik	Biochemistry and Pharmacology
Endothelin pharmacology in the setting of pulmonary hypertension	Project Leader Professor James Angus	Biochemistry and Pharmacology
Establishing the effect of glycine/serine metabolism on skeletal muscle cell growth	Research Project Leader Dr René Koopman	Anatomy and Physiology
Exercise-induced liver-muscle cross-talk and mitochondrial adaptations	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
Exploring new roles for the TGFβ signalling network as a key regulator of skeletal muscle in health and disease	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Fogg laboratory: Surgical Anatomy	Head of Laboratory Associate Professor Quentin Fogg	Anatomy and Physiology
Furness laboratory: Digestive physiology and nutrition	Head of Laboratory Professor John Furness	Anatomy and Physiology
Gregorevic laboratory: Muscle Research and Therapeutics	Head of Laboratory Associate Professor Paul Gregorevic	Anatomy and Physiology
Growth factors and peptide mimetics	Project Leader Dr Susan Northfield	Biochemistry and Pharmacology
Innovative approaches to prepare synthetic, partially synthetic and natural product-based vaccines	Project Leader Professor David Jackson	Microbiology and Immunology
Jackson laboratory: Synthetic vaccine design	Head of Laboratory Professor David Jackson	Microbiology and Immunology
Jonathan Mangum laboratory	Head of Laboratory Dr Jonathan Mangum	Biochemistry and Pharmacology
Koopman laboratory: Clinical nutrition and muscle metabolism	Head of Laboratory Associate Professor René Koopman	Anatomy and Physiology
Laura Edgington-Mitchell laboratory	Head of Research Group Dr Laura Edgington-Mitchell	Biochemistry and Pharmacology
Leann Tilley laboratory	Head of Laboratory, Redmond Barry Distinguished Professor of Biochemistry & Pharmacology, ARC Australian Laureate Fellow (2015-2020) Professor Leann Tilley	Biochemistry and Pharmacology
Learning from skeletal muscles to develop new treatments for cancer	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Lipopeptide-based adjuvanting systems	Project Leader Professor David Jackson	Microbiology and Immunology
Michael Parker laboratory	Head of Laboratory and Director, Bio21 Institute Professor Michael Parker	Biochemistry and Pharmacology
Molecular mechanisms of drug resistance in cancer	Project Leader Dr Jonathon Mangum	Biochemistry and Pharmacology
Molecular mechanisms that contribute to skeletal pain	Head of Laboratory Associate Professor Jason Ivanusic	Anatomy and Physiology
Montgomery laboratory: Metabolic Tissue Cross-Talk	Head of Laboratory Dr Magdalene Montgomery	Anatomy and Physiology
Munsie laboratory: Ethical, legal and social implications of stem cell research	Head of Laboratory Professor Megan Munsie	Anatomy and Physiology
Murray laboratory: Myelin biology	Head of Laboratory Associate Professor Simon Murray	Anatomy and Physiology
Pain management using ultrasound-guided local anaesthetic techniques	Head of Laboratory Associate Professor Jason Ivanusic	Anatomy and Physiology
Patient voices: An analysis of patients’ information-based priorities and needs	Project Leader Professor Megan Munsie	Anatomy and Physiology
Paul Gleeson laboratory	Head of Laboratory Professor Paul Gleeson	Biochemistry and Pharmacology
Paul Gooley laboratory	Head of Laboratory Professor Paul Gooley	Biochemistry and Pharmacology
Peter Crack laboratory	Head of Laboratory Associate Professor Peter Crack	Biochemistry and Pharmacology
Preclinical pharmacology – cardiovascular efficacy and safety R&D	Project Leader Associate Professor Christine Wright	Biochemistry and Pharmacology
Prognostic biomarker and therapeutic target discovery in stroke	Project Leader Dr Jonathon Mangum	Biochemistry and Pharmacology
Project 1. Development of improved cancer vaccines to enhance the efficacy of immunotherapy combination strategies	Project Leader Professor Riccardo Dolcetti	Microbiology and Immunology
Project 2. Identification and characterisation of novel classes of therapeutically relevant tumour neo-antigens	Project Leader Professor Riccardo Dolcetti	Microbiology and Immunology
Relaxin family peptide hormones	Project Leader Associate Professor Tony Hughes	Biochemistry and Pharmacology
Robyn Brown laboratory	Head of Laboratory Dr Robyn M Brown	Biochemistry and Pharmacology
Stuart Ralph laboratory	Head of Laboratory Dr Stuart Ralph	Biochemistry and Pharmacology
The Bonn and Melbourne Research and Graduate School	Melbourne Coordinator Dr Marie Greyer
The Cardiovascular Pharmacology of Snake Venoms From Papua New Guinea and Australia	Project Leader Associate Professor Christine Wright	Biochemistry and Pharmacology
The heart as a central player in tissue cross-talk	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
The link between cardiovascular disease and neurodegeneration – focus on Alzheimer’s disease	Project Leader Associate Professor Christine Wright	Biochemistry and Pharmacology
The Treatment of Papuan Taipan Envenoming in Papua New Guinea	Project Leader Dr David Williams	Biochemistry and Pharmacology
Therapeutics & Translation
Tissue communication in non-alcoholic fatty liver disease (NALFD) and liver fibrosis	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
Tony Hughes & Susan Northfield laboratory	Joint Heads of Laboratory Associate Professor Tony Hughes & Dr Susan Northfield	Biochemistry and Pharmacology
Tony Velkov laboratory	Head of Laboratory Associate Professor Tony Velkov	Biochemistry and Pharmacology
Trovafloxacin – an antibiotic with additional properties	Project Leader Professor James Angus	Biochemistry and Pharmacology
Understanding metabolic cross-talk in health and disease - Focus on type 2 diabetes and fatty liver	Research Project Leader Dr Magdalene Montgomery	Anatomy and Physiology
Unravelling the mysteries of E3 ubiquitin ligase in regulating skeletal muscle size and function	Research Project Leader Associate Professor Paul Gregorevic	Anatomy and Physiology
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Anatomy and Physiology
Wilkinson-Berka laboratory: Retinal vascular biology and inflammation	Head of Laboratory Professor Jennifer Wilkinson-Berka	Anatomy and Physiology

Scholarship of Teaching and Learning

Groups / Projects	Research Lead	Dept / Centre
Clark: Anatomy, Neuroscience and Cell Biology Education Scholarship	Dr Charlotte Clark	Anatomy and Physiology
Heather Verkade: Molecular Biology Education Scholarship	Associate Professor Heather Verkade	Biochemistry and Pharmacology
Lim: Education Scholarship	Dr Saw Hoon Lim	Biochemistry and Pharmacology
Mulhern: Biochemistry and Molecular Biology Education Scholarship	Associate Professor Terry Mulhern	Biochemistry and Pharmacology
Post: Online Teaching Delivery Neuroscience & Anatomy	MSc Ger Post	Anatomy and Physiology
Rank: Anatomy Education Scholarship	Dr Michelle Rank	Anatomy and Physiology
Scholarship of Teaching and Learning
Waller: Microbiology Education Scholarship	Associate Professor Karena Waller	Microbiology and Immunology
Wijburg: Infection and Immunity Education Scholarship	Associate Professor Odilia Wijburg	Microbiology and Immunology
Willems-Jones: Biochemistry & Molecular Biology Education Scholarship	Dr Amber Willems-Jones	Biochemistry and Pharmacology