Biomedical Projects by Theme

Cancer in Biomedicine

Groups / Projects	Research Lead	Dept / Centre
Analysing genetic roles of RNA-binding proteins and alternative splicing in Drosophila stem cells	Project Leader Professor Gary Hime	Anatomy and Neuroscience
Applications of Nanopore sequencing	Project Leader Dr Mike Clark	Anatomy and Neuroscience
Ascher laboratory: Structural biology and bioinformatics	Head of Laboratory Dr David Ascher	Biochemistry and Molecular Biology
Bo&MeRanG Research Projects	Melbourne Coordinator Dr Marie Greyer
Bogoyevitch laboratory: Regulatory biology	Head of Laboratory Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Cancer in Biomedicine
Cheng laboratory: Molecular enzymology of protein kinases and phosphatases involved in human diseases	Head of Laboratory Associate Professor Heung-Chin Cheng	Biochemistry and Molecular Biology
Clinical Proteomics	Project Leader Dr Jonathon Mangum	Pharmacology and Therapeutics
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Head of Laboratory Professor Matthew Watt	Physiology
E3 Ubiquitin Ligase in skeletal muscle	Head of Laboratory Associate Professor Paul Gregorevic	Physiology
EMT regulators in intestinal and germline stem cells	Project Leader Professor Gary Hime	Anatomy and Neuroscience
Gregorevic laboratory: Muscle Research and Therapeutics	Head of Laboratory Associate Professor Paul Gregorevic	Physiology
Hime laboratory: Stem cell genetics	Head of Laboratory Professor Gary Hime	Anatomy and Neuroscience
Hinde laboratory: Biophysics of Nuclear Organisation	Head of Research Group Dr Elizabeth Hinde	Biochemistry and Molecular Biology
Mangum Lab: Translational Proteomics	Head of Laboratory Dr Jonathan Mangum	Pharmacology and Therapeutics
Mantamadiotis laboratory: Brain Cancer Molecular Biology	Dr Theo Mantamadiotis	Microbiology and Immunology
Migration of melanoma cells in the neural crest environment	Project Leader Dr Sonja McKeown	Anatomy and Neuroscience
Molecular mechanisms of drug resistance in cancer	Project Leader Dr Jonathon Mangum	Pharmacology and Therapeutics
Novel regulators of germline stem cells	Project Leader Professor Gary HIme	Anatomy and Neuroscience
Parker Laboratory: Structural biology and computational drug design	Head of Laboratory and Director, Bio21 Institute Professor Michael Parker	Biochemistry and Molecular Biology
Reid laboratory: Proteomics and lipidomics in health and disease	Head of Laboratory Professor Gavin E. Reid	Biochemistry and Molecular Biology
Restoring immunocompetency in Chronic Lymphocytic Leukemia	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
Rouiller laboratory: Understanding how molecular machines function through cryo-electron microscopy	Associate Professor Isabelle Rouiller	Biochemistry and Molecular Biology
Taylor: Jack Brockhoff Reconstructive Plastic Surgery Research Unit	Head of Unit Professor Ian Taylor	Anatomy and Neuroscience
Transcriptional regulation of intestinal organoid differentiation	Project Leader Professor Gary Hime	Anatomy and Neuroscience
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Physiology

Cardio-Respiratory

Groups / Projects	Research Lead	Dept / Centre
Brain networks processing respiratory sensations	Project Leader Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Effects of hypertension on renal and hindquarter vascular reactivity in vivo and in vitro	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
Endothelin pharmacology in the setting of pulmonary hypertension	Project Leader Professor James Angus	Pharmacology and Therapeutics
Human brain networks processing respiratory sensations	Project Leader Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Lung Disease Research Laboratory	Head of Laboratory Professor Gary P Anderson	Pharmacology and Therapeutics
Mazzone laboratory: Respiratory Sensory Neuroscience	Head of Research Group Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Modelling sensory neuron-epithelial interactions	Project Leader Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Novel technique to determine the pKA of clonidine at prejunctional α2-adrenoceptors in sympathetic transmission	Project Leader Professor James Angus	Pharmacology and Therapeutics
Pathogenesis of chronic lung disease	Head of Laboratory Dr Michelle Hansen	Pharmacology and Therapeutics
Preclinical pharmacology – cardiovascular efficacy and safety R&D	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
Reassessment of α1-adrenoceptor mechanism in artery contraction: role of ATP and pannexin channels	Project Leader Professor James Angus	Pharmacology and Therapeutics
Stroud laboratory: Mitochondrial Systems Biology	Head of Research Group Dr David Stroud	Biochemistry and Molecular Biology
The cardiovascular pharmacology of snake venoms from Papua New Guinea and Australia	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
The innate immune system in the respiratory tract	Project Leader Professor David Jackson	Microbiology and Immunology
The link between cardiovascular disease and neurodegeneration – focus on Alzheimer’s disease	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
Transcriptional profiling of sensory neurons	Project Leader Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Trovafloxacin – an antibiotic with additional properties	Project Leader Professor James Angus	Pharmacology and Therapeutics
Wright laboratory: Cardiovascular Therapeutics Unit	Head of Laboratory Associate Professor Christine E Wright	Pharmacology and Therapeutics

Cell Signalling

Groups / Projects	Research Lead	Dept / Centre
A new function of the cytokine BAFF in dendritic cell maturation: Implications for immunity and cancers	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
Analysing genetic roles of RNA-binding proteins and alternative splicing in Drosophila stem cells	Project Leader Professor Gary Hime	Anatomy and Neuroscience
Bo&MeRanG Research Projects	Melbourne Coordinator Dr Marie Greyer
Bogoyevitch laboratory: Regulatory biology	Head of Laboratory Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Brock laboratory: Autonomic and sensory neuroscience	Head of Laboratory Associate Professor James Brock	Anatomy and Neuroscience
Can drug-like mimetics of BDNF promote remyelination after injury?	Project Leader Dr Junhua Xiao	Anatomy and Neuroscience
Cell Signalling
Cellular trafficking and male fertility	Project Leader Professor Gary Hime	Anatomy and Neuroscience
Cheng laboratory: Molecular enzymology of protein kinases and phosphatases involved in human diseases	Head of Laboratory Associate Professor Heung-Chin Cheng	Biochemistry and Molecular Biology
Crack laboratory: Neuropharmacology	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Discovering and characterizing new genes involved in innate immunity, tissue injury and fibrosis	Project Leader Professor Christine Wells	Anatomy and Neuroscience
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Head of Laboratory Professor Matthew Watt	Physiology
E3 Ubiquitin Ligase in skeletal muscle	Head of Laboratory Associate Professor Paul Gregorevic	Physiology
EMT regulators in intestinal and germline stem cells	Project Leader Professor Gary Hime	Anatomy and Neuroscience
Gleeson laboratory: Membrane trafficking and protein sorting in health and disease and development of new therapeutics	Head of Laboratory Professor Paul Gleeson	Biochemistry and Molecular Biology
Gregorevic laboratory: Muscle Research and Therapeutics	Head of Laboratory Associate Professor Paul Gregorevic	Physiology
Gunnersen laboratory: Neuron development and plasticity	Head of Laboratory Dr Jenny Gunnersen	Anatomy and Neuroscience
Hime laboratory: Stem cell genetics	Head of Laboratory Professor Gary Hime	Anatomy and Neuroscience
Hinde laboratory: Biophysics of Nuclear Organisation	Head of Research Group Dr Elizabeth Hinde	Biochemistry and Molecular Biology
How BDNF signalling controls myelination?	Project Leader Dr Simon Murray	Anatomy and Neuroscience
How sensory signals are detected: Structure function relationships in peripheral sensory nerve terminals	Project Leader Associate Professor James Brock	Anatomy and Neuroscience
Improving bladder health after spinal cord injury	Project Leader Associate Professor James Brock	Anatomy and Neuroscience
Mantamadiotis laboratory: Brain Cancer Molecular Biology	Dr Theo Mantamadiotis	Microbiology and Immunology
Mechanisms of growth factor signalling	Project Leader Dr Simon Murray	Anatomy and Neuroscience
Murray & Xiao laboratory: Neurotrophin and myelin	Joint Heads of Laboratory Dr Simon Murray & Dr Junhua Xiao	Anatomy and Neuroscience
Novel regulators of germline stem cells	Project Leader Professor Gary HIme	Anatomy and Neuroscience
The GDNF family, peripheral nerve regeneration and pain	Project Leader Professor Janet Keast	Anatomy and Neuroscience
The influence of neurotrophin signalling upon the generation of myelin	Project Leader Dr Simon Murray	Anatomy and Neuroscience
The Role of CXCR7 in Tissue Fibrosis	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
The unique features of visceral pain	Project Leader Professor Janet Keast	Anatomy and Neuroscience
Transcriptional regulation of intestinal organoid differentiation	Project Leader Professor Gary Hime	Anatomy and Neuroscience
Uncovering the interplay between innate immunity and the blood brain barrier in disorders of the CNS	Project Leader Professor Christine Wells	Anatomy and Neuroscience
Understanding the interaction between microbiota and T cell immunity	Project Leader Associate Professor Sammy Bedoui	Microbiology and Immunology
Understanding the molecular basis of myelin repair	Project Leader Dr Junhua Xiao	Anatomy and Neuroscience
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Physiology

Cellular Imaging & Structural Biology

Groups / Projects	Research Lead	Dept / Centre
Bo&MeRanG Research Projects	Melbourne Coordinator Dr Marie Greyer
Brock laboratory: Autonomic and sensory neuroscience	Head of Laboratory Associate Professor James Brock	Anatomy and Neuroscience
Can drug-like mimetics of BDNF promote remyelination after injury?	Project Leader Dr Junhua Xiao	Anatomy and Neuroscience
Cellular Imaging & Structural Biology
Dendritic cell maturation following different microbial stimulation	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Dental morphology	Project Leader Dr Varsha Pilbrow	Anatomy and Neuroscience
Factors that accelerate photoreceptor death: The role of purines	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
Fletcher laboratory: Visual neuroscience	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
Gleeson laboratory: Membrane trafficking and protein sorting in health and disease and development of new therapeutics	Head of Laboratory Professor Paul Gleeson	Biochemistry and Molecular Biology
Glial cells as a source of progenitor cells in degenerative disease	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
Gooley laboratory: Structural biology of disease	Head of Laboratory Associate Professor Paul Gooley	Biochemistry and Molecular Biology
Gunnersen laboratory: Neuron development and plasticity	Head of Laboratory Dr Jenny Gunnersen	Anatomy and Neuroscience
Hatters laboratory: Protein misfolding and proteostasis in neurodegenerative diseases	Head of Laboratory Associate Professor Danny Hatters	Biochemistry and Molecular Biology
Heath laboratory: CD8 T lymphocytes, dendritic cells, self tolerance and immunity	Head of Laboratory Professor William (Bill) Heath	Microbiology and Immunology
Hinde laboratory: Biophysics of Nuclear Organisation	Head of Research Group Dr Elizabeth Hinde	Biochemistry and Molecular Biology
How BDNF signalling controls myelination?	Project Leader Dr Simon Murray	Anatomy and Neuroscience
How sensory signals are detected: Structure function relationships in peripheral sensory nerve terminals	Project Leader Associate Professor James Brock	Anatomy and Neuroscience
Imaging effector and memory T cell responses in the skin following Herpes Simplex Virus-1 infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Imaging the priming of CD8 Killer T cell responses to Herpes Simplex Virus-1 skin infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Improved vaccines by targeting to dendritic cells	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Improving bladder health after spinal cord injury	Project Leader Associate Professor James Brock	Anatomy and Neuroscience
Intraepithelial T cells in anti-viral immunity	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
Intravital imaging of T cell responses in the brain during cerebral malaria infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Live cell imaging of neural crest cell migration along the developing gut	Head of Laboratory Professor Heather Young Head of Laboratory Professor Heather Young	Anatomy and Neuroscience
Lymphoid stromal cell responses to infection	Project Leader Associate Professor Scott Mueller	Microbiology and Immunology
Malaria and Tissue Resident Memory T cells (TRM) in the liver	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Mechanisms of growth factor signalling	Project Leader Dr Simon Murray	Anatomy and Neuroscience
Migration of melanoma cells in the neural crest environment	Project Leader Dr Sonja McKeown	Anatomy and Neuroscience
Mueller laboratory: Adaptive immune responses to infection, lymphoid stromal cells, and imaging the immune system	Head of Laboratory Associate Professor Scott Mueller	Microbiology and Immunology
Murray & Xiao laboratory: Neurotrophin and myelin	Joint Heads of Laboratory Dr Simon Murray & Dr Junhua Xiao	Anatomy and Neuroscience
Nervous regulation of T cell migration and anti-viral Immunity	Project Leader Associate Professor Scott Mueller	Microbiology and Immunology
Parker Laboratory: Structural biology and computational drug design	Head of Laboratory and Director, Bio21 Institute Professor Michael Parker	Biochemistry and Molecular Biology
Pilbrow laboratory: Physical (biological) anthropology	Head of Laboratory Dr Varsha Pilbrow	Anatomy and Neuroscience
Priming of T cell responses to viral infection	Project Leader Associate Professor Scott Mueller	Microbiology and Immunology
Rouiller laboratory: Understanding how molecular machines function through cryo-electron microscopy	Associate Professor Isabelle Rouiller	Biochemistry and Molecular Biology
Self-tolerance: Interactions between thymic stroma and dendritic cells	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Skeletal morphology	Project Leader Dr Varsha Pilbrow	Anatomy and Neuroscience
Stojanovski laboratory: Mitochondrial biogenesis in health and disease	Head of Laboratory Dr Diana Stojanovski	Biochemistry and Molecular Biology
T cell responses in the brain during experimental cerebral malaria infection	Project Leader Associate Professor Scott Mueller	Microbiology and Immunology
Taylor: Jack Brockhoff Reconstructive Plastic Surgery Research Unit	Head of Unit Professor Ian Taylor	Anatomy and Neuroscience
The influence of neurotrophin signalling upon the generation of myelin	Project Leader Dr Simon Murray	Anatomy and Neuroscience
The role of glia in inner retinal changes during retinal degeneration	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
The role of glial cells in retinal vascular disease	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
The role of microglia in age-related macular degeneration	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
Tilley laboratory: Measuring and modelling malaria parasites to develop new antimalarials	Head of Laboratory, ARC Australian Laureate Fellow Professor Leann Tilley	Biochemistry and Molecular Biology
Tissue-resident memory T cells in the skin	Project Leader Associate Professor Scott Mueller	Microbiology and Immunology
Understanding neuro-urothelial communication	Project Leader Professor Janet Keast	Anatomy and Neuroscience
Understanding the molecular basis of myelin repair	Project Leader Dr Junhua Xiao	Anatomy and Neuroscience
Using biochemical approaches to investigating the trafficking and mechanism of action of the antiviral molecule, IFITM3	Project Leader Dr Linda Wakim	Microbiology and Immunology
Vaccination against liver-stage Plasmodium for malaria prevention	Project Leader Professor William (Bill) Heath	Microbiology and Immunology

Infection & Immunity

Groups / Projects	Research Lead	Dept / Centre
"Clock-off time" for inflammation and remodelling in chronic inflammatory diseases: casein kinase inhibitors	Primary Supervisor Professor Alastair Stewart	Pharmacology and Therapeutics
A new function of the cytokine BAFF in dendritic cell maturation: Implications for immunity and cancers	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
A universal vaccine against influenza A	Project Leader Professor David Jackson	Microbiology and Immunology
Antibody dependent cellular cytotoxicity - a neglected anti-HIV iImmune response!	Project Leaders Professor Stephen Kent, Dr Amy Chung, Dr Matt Parsons	Microbiology and Immunology
Antimicrobial resistant bacterial pathogens	Project Leader Professor Ben Howden	Microbiology and Immunology
Application of genomics to public health and clinical microbiology	Project Leader Professor Ben Howden	Microbiology and Immunology
Ascher laboratory: Structural biology and bioinformatics	Head of Laboratory Dr David Ascher	Biochemistry and Molecular Biology
Australian bite and sting trends: Australian Venomous Injury Project (AVIP)	Project Leader Dr Ronelle Welton	Pharmacology and Therapeutics
Australian Venom Research Unit	Head of Unit Dr David Williams	Pharmacology and Therapeutics
Autophagy and Norovirus replication	Professor Jason Mackenzie	Microbiology and Immunology
Biolpolymer-based vaccine delivery systems	Project Leader Professor David Jackson	Microbiology and Immunology
Bo&MeRanG Research Projects	Melbourne Coordinator Dr Marie Greyer
Bogoyevitch laboratory: Regulatory biology	Head of Laboratory Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Brooks laboratory: Innate immunity; anti-viral immunity	Head of Laboratory Professor Andrew Brooks	Microbiology and Immunology
Brown laboratory: Immunology; virology; vaccinology	Head of Laboratory Professor Lorena (Lori) Brown	Microbiology and Immunology
Carbone laboratory: Immune response to herpes simplex virus	Head of Laboratory Professor Francis (Frank) Carbone	Microbiology and Immunology
Cell surface receptors for attachment and entry of influenza virus into cells of the innate immune system	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
Chronic immune activation during treated HIV disease	Project Leader Professor Damian Purcell	Microbiology and Immunology
Combined influenza-AIDS vaccines and mucosal vaccinations	Project Leader Professor Stephen Kent	Microbiology and Immunology
Correlates of severe and fatal influenza disease in high-risk groups	Head of Laboratory Associate Professor Katherine Kedzierska	Microbiology and Immunology
Coulson laboratory: Rotavirus pathogenesis and immunity	Head of Laboratory Associate Professor Barbara Coulson	Microbiology and Immunology
Crack laboratory: Neuropharmacology	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Deciphering the relative contributions of different dendritic cells to killer T cell responses	Project Leader Associate Professor Sammy Bedoui	Microbiology and Immunology
Delineating how CD4 T cells ‘help’ establishing effective killer T cell responses	Project Leader Associate Professor Sammy Bedoui	Microbiology and Immunology
Dendritic cell maturation following different microbial stimulation	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Design, development and testing of HIV vaccines	Project Leader Professor Damian Purcell	Microbiology and Immunology
Developing new therapies for Systemic Lupus Erythematosus	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
Development and application of soft culturing microenvironment for novel drug discovery	Primary Supervisor Professor Alastair Stewart	Pharmacology and Therapeutics
Development of a self-adjuvanting vaccine for enterotoxigenic Escherichia coli (ETEC)	Project Leader Professor David Jackson	Microbiology and Immunology
Development of new types of antimicrobial agents	Project Leader Professor Roy Robins-Browne	Microbiology and Immunology
Discovering and characterizing new genes involved in innate immunity, tissue injury and fibrosis	Project Leader Professor Christine Wells	Anatomy and Neuroscience
Edgington-Mitchell laboratory: Protease Pathophysiology	Head of Research Group Dr Laura Edgington-Mitchell	Biochemistry and Molecular Biology
Enterococcus faecium	Project Leader Professor Ben Howden	Microbiology and Immunology
Furness laboratory: Digestive physiology and nutrition	Head of Laboratory Professor John Furness	Anatomy and Neuroscience
Gebhardt laboratory: Adaptive immune responses to virus infections	Head of Laboratory Associate Professor Thomas Gebhardt	Microbiology and Immunology
Gleeson laboratory: Membrane trafficking and protein sorting in health and disease and development of new therapeutics	Head of Laboratory Professor Paul Gleeson	Biochemistry and Molecular Biology
Glucocorticoid responsiveness in the lung: impact of inflammation and infection	Primary Supervisor Professor Alastair Stewart	Pharmacology and Therapeutics
Godfrey laboratory: The development and function of unconventional T cells	Head of Laboratory Professor Dale Godfrey	Microbiology and Immunology
Gooley laboratory: Structural biology of disease	Head of Laboratory Associate Professor Paul Gooley	Biochemistry and Molecular Biology
Gut health: an intersection of food, environment, animal production and global health	Project Supervisor Professor John B Furness	Anatomy and Neuroscience
Heath laboratory: CD8 T lymphocytes, dendritic cells, self tolerance and immunity	Head of Laboratory Professor William (Bill) Heath	Microbiology and Immunology
High fat diets, gut health and diabetes	Project Supervisor Dr Rachel McQuade	Anatomy and Neuroscience
Holt laboratory: Pathogen genomics and bioinformatics	Head of Laboratory A/Prof Kathryn Holt	Biochemistry and Molecular Biology
How is the immunological T cell memory generated?	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Howden laboratory: Molecular epidemiology, genomics and pathogenesis of antimicrobial resistant bacteria	Head of Laboratory \| Director of MDU Professor Ben Howden	Microbiology and Immunology
Identifying the mechanisms of immune cell development in peripheral tissues	Project Leader Dr Laura Mackay	Microbiology and Immunology
Imaging effector and memory T cell responses in the skin following Herpes Simplex Virus-1 infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Imaging the priming of CD8 Killer T cell responses to Herpes Simplex Virus-1 skin infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Improved vaccines by targeting to dendritic cells	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Infection & Immunity
Influenza A virus PB1-F2 Protein: a putative virulence factor and initiator of inflammation	Project Leader Dr Julie McAuley	Microbiology and Immunology
Influenza–specific ADCC: Role in a universal flu vaccine?	Project Leader Professor Stephen Kent	Microbiology and Immunology
Innate T cell recognition and development	Project Leader Dr Daniel Pellicci	Microbiology and Immunology
Innovative approaches to prepare synthetic, partially synthetic and natural product-based vaccines	Project Leader Professor David Jackson	Microbiology and Immunology
Intraepithelial T cells in anti-viral immunity	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
Intravital imaging of T cell responses in the brain during cerebral malaria infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Investigation of HSV latency and reactivation	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
Jackson laboratory: Synthetic vaccine design	Head of Laboratory Professor David Jackson	Microbiology and Immunology
Kedzierska laboratory: Immunity to pandemic and newly emerged influenza viruses	Head of Laboratory Associate Professor Katherine Kedzierska	Microbiology and Immunology
Kent laboratory: HIV vaccines; immune responses to HIV-1; immunotherapy	Head of Laboratory Professor Stephen Kent	Microbiology and Immunology
Klebsiella pneumoniae	Project Leader Professor Dick Strugnell	Microbiology and Immunology
Lawson laboratory: Neurodegenerative disease caused by prions	Head of Laboratory Associate Professor Vicki Lawson	Microbiology and Immunology
Lew laboratory: Theoretical and empirical pharmacology	Head of Laboratory Dr Michael Lew	Pharmacology and Therapeutics
Lipopeptide-based adjuvanting systems	Project Leader Professor David Jackson	Microbiology and Immunology
Lung Disease Research Laboratory	Head of Laboratory Professor Gary P Anderson	Pharmacology and Therapeutics
Lung Health Research Centre		Pharmacology and Therapeutics
Lymphoid stromal cell responses to infection	Project Leader Associate Professor Scott Mueller	Microbiology and Immunology
Mackay (F) laboratory: B lymphocytes, BAFF, autoimmunity and cancer	Head of Laboratory Head of School of Biomedical Sciences Professor Fabienne Mackay	Microbiology and Immunology
Mackay (L) laboratory: Tissue-resident memory T cells; lymphocyte differentiation; peripheral immunity	Senior Lecturer & NHMRC Career Development Fellow, HHMI-Gates International Research Scholar Dr Laura Mackay	Microbiology and Immunology
Mackenzie laboratory: Intracellular virus replication and innate immunity	Head of Laboratory Professor Jason Mackenzie	Microbiology and Immunology
Malaria and Tissue Resident Memory T cells (TRM) in the liver	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
McCluskey laboratory: Role of MAIT cells in health and disease	Head of Laboratory, Redmond Barry Distinguished Professor Professor James McCluskey	Microbiology and Immunology
McConville laboratory: Molecular microbiology	Head of Laboratory Professor Malcolm McConville	Biochemistry and Molecular Biology
Mechanisms underlying early generation of human T cell memory	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Memory T cell responses in the lung during virus infection	Project Leader Dr Linda Wakim	Microbiology and Immunology
Mintern laboratory: Vaccine biology	Head of Laboratory Dr Justine Mintern	Biochemistry and Molecular Biology
Modulation of intestinal inflammation through nerve stimulation	Project Supervisor Dr Martin Stebbing	Anatomy and Neuroscience
Mueller laboratory: Adaptive immune responses to infection, lymphoid stromal cells, and imaging the immune system	Head of Laboratory Associate Professor Scott Mueller	Microbiology and Immunology
Munsie laboratory: Ethical, legal and social implications of stem cell research	Head of Laboratory Associate Professor Megan Munsie	Anatomy and Neuroscience
Mycobacterium ulcerans	Project Leader Professor TIm Stinear	Microbiology and Immunology
Nanoparticle HIV vaccines	Project Leader Professor Stephen Kent	Microbiology and Immunology
Nanoparticle Modulation of Mast Cell Function	Project Leader Dr Graham Mackay	Pharmacology and Therapeutics
Nerve pathways responding to and controlling inflammation in the intestine	Project Supervisor Dr Martin Stebbing	Anatomy and Neuroscience
Nervous regulation of T cell migration and anti-viral Immunity	Project Leader Associate Professor Scott Mueller	Microbiology and Immunology
Newton laboratory: Virulence strategies of intracellular bacterial pathogens	Head of Laboratory Dr Hayley Newton	Microbiology and Immunology
NK cell receptor biology	Project Leader Professor Andrew Brooks	Microbiology and Immunology
NKT cells, MAIT cells, CD1-restricted T cells and HIV	Project Leader Professor Stephen Kent	Microbiology and Immunology
Non-classical MHC and Class 1-like molecules	Project Leader Professor Andrew Brooks	Microbiology and Immunology
Norovirus replication and innate immunity	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
Novel Mast Cell-Derived Mediators	Project Leader Dr Graham Mackay	Pharmacology and Therapeutics
Nutrition: The control of gut hormone release by nutrients	Project Supervisor Professor John B Furness	Anatomy and Neuroscience
Parker Laboratory: Structural biology and computational drug design	Head of Laboratory and Director, Bio21 Institute Professor Michael Parker	Biochemistry and Molecular Biology
Passive antibody immunity for use in combination microbicides	Project Leader Professor Damian Purcell	Microbiology and Immunology
Pathogenesis of chronic lung disease	Head of Laboratory Dr Michelle Hansen	Pharmacology and Therapeutics
Priming of T cell responses to viral infection	Project Leader Associate Professor Scott Mueller	Microbiology and Immunology
Purcell laboratory: Viral RNA elements, regulation of HIV replication, HIV antibody vaccine	Head of Laboratory Professor Damian Purcell	Microbiology and Immunology
Ralph laboratory: Drug targets and gene regulation in Plasmodium falciparum	Head of Laboratory Dr Stuart Ralph	Biochemistry and Molecular Biology
Reading laboratory: Innate immune detection and response to respiratory virus infections	Head of Laboratory Associate Professor Patrick Reading	Microbiology and Immunology
Regulation of Mast Cell Activation	Project Leader Dr Graham Mackay	Pharmacology and Therapeutics
Restoring immunocompetency in Chronic Lymphocytic Leukemia	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
RNA mediated control of HIV-1 gene expression	Project Leader Professor Damian Purcell	Microbiology and Immunology
Robins-Browne laboratory: Medical bacteriology, pathogenesis, bacterial genetics, therapeutics	Head of Laboratory Professor Roy Robins-Browne	Microbiology and Immunology
Role of cellular lipids during Flavivirus replication	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
Role of innate signals in inducing protective T cell immunity	Project Leader Associate Professor Sammy Bedoui	Microbiology and Immunology
Rotavirus induction and evasion of innate immunity	Project Leader Associate Professor Barbara Coulson	Microbiology and Immunology
Rotavirus modulation of type 1 diabetes development	Project Leader Associate Professor Barbara Coulson	Microbiology and Immunology
Rotavirus-cell binding and entry	Project Leader Associate Professor Barbara Coulson	Microbiology and Immunology
Rouiller laboratory: Understanding how molecular machines function through cryo-electron microscopy	Associate Professor Isabelle Rouiller	Biochemistry and Molecular Biology
Salmonella Typhimurium	Project Leader Professor Dick Strugnell	Microbiology and Immunology
Self-tolerance: Interactions between thymic stroma and dendritic cells	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Simmons laboratory: Dengue; pathogenesis, epidemiology, therapeutics, entomology	Head of Laboratory Professor Cam Simmons	Microbiology and Immunology
Soluble barriers to influenza virus infection	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
Staphylococcus aureus & Enterococcus faecium	Project Leader Professor Tim Stinear	Microbiology and Immunology
Staphylococcus aureus and Staphylococcus epidermidis	Project Leader Professor Ben Howden	Microbiology and Immunology
Stewart Laboratory: Mechanopharmacology	Head of Laboratory Professor Alastair Stewart	Pharmacology and Therapeutics
Stinear laboratory: Bacterial pathogenomics	Head of Laboratory Professor Tim Stinear	Microbiology and Immunology
Strugnell laboratory: Bacterial pathogenesis and host responses	Head of Laboratory Professor Dick Strugnell	Microbiology and Immunology
T cell responses in the brain during experimental cerebral malaria infection	Project Leader Associate Professor Scott Mueller	Microbiology and Immunology
T cells in peripheral immunity	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
The Cardiovascular Pharmacology of Snake Venoms From Papua New Guinea and Australia	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
The innate immune system in the respiratory tract	Project Leader Professor David Jackson	Microbiology and Immunology
The mechanisms of viral escape in murine and human influenza infection	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
The role of CD4+ T cells in viral infections	Project Leader Professor Andrew Brooks	Microbiology and Immunology
The Role of CXCR7 in Tissue Fibrosis	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
The role of innate immune cells in protection and pathology during influenza virus infection	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
The role of resident memory T cells in barrier immunity and autoimmune disease	Project Leader Dr Laura Mackay	Microbiology and Immunology
The Treatment of Papuan Taipan Envenoming in Papua New Guinea	Project Leader Dr David Williams	Pharmacology and Therapeutics
Tilley laboratory: Measuring and modelling malaria parasites to develop new antimalarials	Head of Laboratory, ARC Australian Laureate Fellow Professor Leann Tilley	Biochemistry and Molecular Biology
Tissue-resident memory T cells in the skin	Project Leader Associate Professor Scott Mueller	Microbiology and Immunology
Tracking phenotypically and functionally distinct T cell subsets via T cell repertoire diversity	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Uncovering the interplay between innate immunity and the blood brain barrier in disorders of the CNS	Project Leader Professor Christine Wells	Anatomy and Neuroscience
Understanding the interaction between microbiota and T cell immunity	Project Leader Associate Professor Sammy Bedoui	Microbiology and Immunology
Understanding the regulation of tissue-resident memory T cell development	Project Leader Dr Laura Mackay	Microbiology and Immunology
Understanding ‘universal’ influenza-specific CD8+ T cell responses	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Using biochemical approaches to investigating the trafficking and mechanism of action of the antiviral molecule, IFITM3	Project Leader Dr Linda Wakim	Microbiology and Immunology
Vaccination against liver-stage Plasmodium for malaria prevention	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
van Driel laboratory: Immune responses to pathogens	Head of Laboratory Professor Ian van Driel	Biochemistry and Molecular Biology
Velkov laboratory: Antiinfective pharmacology	Head of Laboratory Associate Professor Tony Velkov	Pharmacology and Therapeutics
Villadangos laboratory: Antigen presenting cells & molecules that initiate T cell immunity against pathogens and cancer	Head of Laboratory Professor Jose Villadangos	Microbiology and Immunology
Viral interactions with the innate immune system	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
Visualization and formation West Nile Virus replication complexes	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
Wakim laboratory: Antiviral molecules, mucosal immunology, influenza virus, tissue resident memory T cells	Head of Laboratory Dr Linda Wakim	Microbiology and Immunology
Wells laboratory: Stem cell systems	Head of Laboratory Professor Christine Wells	Anatomy and Neuroscience
West Nile Virus replication and cellular stress responses	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
Wolbachia to stop dengue transmission in Vietnam and Indonesia	Project Leader Professor Cameron Simmons	Microbiology and Immunology

145

Molecular Mechanisms of Disease

Groups / Projects	Research Lead	Dept / Centre
"Clock-off time" for inflammation and remodelling in chronic inflammatory diseases: casein kinase inhibitors	Primary Supervisor Professor Alastair Stewart	Pharmacology and Therapeutics
A universal vaccine against influenza A	Project Leader Professor David Jackson	Microbiology and Immunology
Antibody dependent cellular cytotoxicity - a neglected anti-HIV iImmune response!	Project Leaders Professor Stephen Kent, Dr Amy Chung, Dr Matt Parsons	Microbiology and Immunology
Antimicrobial resistant bacterial pathogens	Project Leader Professor Ben Howden	Microbiology and Immunology
Application of genomics to public health and clinical microbiology	Project Leader Professor Ben Howden	Microbiology and Immunology
Applications of Nanopore sequencing	Project Leader Dr Mike Clark	Anatomy and Neuroscience
Ascher laboratory: Structural biology and bioinformatics	Head of Laboratory Dr David Ascher	Biochemistry and Molecular Biology
Autophagy and Norovirus replication	Professor Jason Mackenzie	Microbiology and Immunology
Biolpolymer-based vaccine delivery systems	Project Leader Professor David Jackson	Microbiology and Immunology
Bo&MeRanG Research Projects	Melbourne Coordinator Dr Marie Greyer
Bogoyevitch laboratory: Regulatory biology	Head of Laboratory Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Brain networks processing respiratory sensations	Project Leader Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Brooks laboratory: Innate immunity; anti-viral immunity	Head of Laboratory Professor Andrew Brooks	Microbiology and Immunology
Brown laboratory: Immunology; virology; vaccinology	Head of Laboratory Professor Lorena (Lori) Brown	Microbiology and Immunology
Can drug-like mimetics of BDNF promote remyelination after injury?	Project Leader Dr Junhua Xiao	Anatomy and Neuroscience
Cappai laboratory: Neurodegeneration and Brain Injury	Head of Laboratory Professor Roberto Cappai	Pharmacology and Therapeutics
Carbone laboratory: Immune response to herpes simplex virus	Head of Laboratory Professor Francis (Frank) Carbone	Microbiology and Immunology
Cell surface receptors for attachment and entry of influenza virus into cells of the innate immune system	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
Cheng laboratory: Molecular enzymology of protein kinases and phosphatases involved in human diseases	Head of Laboratory Associate Professor Heung-Chin Cheng	Biochemistry and Molecular Biology
Chronic immune activation during treated HIV disease	Project Leader Professor Damian Purcell	Microbiology and Immunology
Clark laboratory: Transcriptomics and Neurogenetics	Head of Laboratory Dr Mike Clark	Anatomy and Neuroscience
Combined influenza-AIDS vaccines and mucosal vaccinations	Project Leader Professor Stephen Kent	Microbiology and Immunology
Correlates of severe and fatal influenza disease in high-risk groups	Head of Laboratory Associate Professor Katherine Kedzierska	Microbiology and Immunology
Coulson laboratory: Rotavirus pathogenesis and immunity	Head of Laboratory Associate Professor Barbara Coulson	Microbiology and Immunology
Crack laboratory: Neuropharmacology	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Crouch laboratory: Neurodegenerative disease	Head of Laboratory Dr Peter Crouch	Pharmacology and Therapeutics
De Iongh laboratory: Ocular development laboratory	Head of Laboratory Associate Professor Robb de Iongh	Anatomy and Neuroscience
Deciphering the relative contributions of different dendritic cells to killer T cell responses	Project Leader Associate Professor Sammy Bedoui	Microbiology and Immunology
Delineating how CD4 T cells ‘help’ establishing effective killer T cell responses	Project Leader Associate Professor Sammy Bedoui	Microbiology and Immunology
Dendritic cell maturation following different microbial stimulation	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Design, development and testing of HIV vaccines	Project Leader Professor Damian Purcell	Microbiology and Immunology
Developing new therapies for Systemic Lupus Erythematosus	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
Development of a self-adjuvanting vaccine for enterotoxigenic Escherichia coli (ETEC)	Project Leader Professor David Jackson	Microbiology and Immunology
Development of autonomic and nociceptive circuits	Project Leader Professor Janet Keast	Anatomy and Neuroscience
Development of new types of antimicrobial agents	Project Leader Professor Roy Robins-Browne	Microbiology and Immunology
Discovering and characterizing new genes involved in innate immunity, tissue injury and fibrosis	Project Leader Professor Christine Wells	Anatomy and Neuroscience
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Head of Laboratory Professor Matthew Watt	Physiology
Dodd laboratory: Metabolic Neuroscience	Head of Laboratory Dr Garron Dodd	Physiology
E3 Ubiquitin Ligase in skeletal muscle	Head of Laboratory Associate Professor Paul Gregorevic	Physiology
Edgington-Mitchell laboratory: Protease Pathophysiology	Head of Research Group Dr Laura Edgington-Mitchell	Biochemistry and Molecular Biology
Enterococcus faecium	Project Leader Professor Ben Howden	Microbiology and Immunology
Factors that accelerate photoreceptor death: The role of purines	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
Fletcher laboratory: Visual neuroscience	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
Furness laboratory: Digestive physiology and nutrition	Head of Laboratory Professor John Furness	Anatomy and Neuroscience
Gebhardt laboratory: Adaptive immune responses to virus infections	Head of Laboratory Associate Professor Thomas Gebhardt	Microbiology and Immunology
Gleeson laboratory: Membrane trafficking and protein sorting in health and disease and development of new therapeutics	Head of Laboratory Professor Paul Gleeson	Biochemistry and Molecular Biology
Glial cells as a source of progenitor cells in degenerative disease	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
Godfrey laboratory: The development and function of unconventional T cells	Head of Laboratory Professor Dale Godfrey	Microbiology and Immunology
Gooley laboratory: Structural biology of disease	Head of Laboratory Associate Professor Paul Gooley	Biochemistry and Molecular Biology
Gregorevic laboratory: Muscle Research and Therapeutics	Head of Laboratory Associate Professor Paul Gregorevic	Physiology
Griffin laboratory: Functional and mis-functional protein-protein interactions	Head of Laboratory Dr Michael Griffin	Biochemistry and Molecular Biology
Gunnersen laboratory: Neuron development and plasticity	Head of Laboratory Dr Jenny Gunnersen	Anatomy and Neuroscience
Hatters laboratory: Protein misfolding and proteostasis in neurodegenerative diseases	Head of Laboratory Associate Professor Danny Hatters	Biochemistry and Molecular Biology
Heath laboratory: CD8 T lymphocytes, dendritic cells, self tolerance and immunity	Head of Laboratory Professor William (Bill) Heath	Microbiology and Immunology
Hinde laboratory: Biophysics of Nuclear Organisation	Head of Research Group Dr Elizabeth Hinde	Biochemistry and Molecular Biology
How BDNF signalling controls myelination?	Project Leader Dr Simon Murray	Anatomy and Neuroscience
How does GM-CSF prevent brain damage after traumatic injury?	Head of Laboratory Dr Jenny Gunnersen Project Leader Dr Sandy Shultz	Anatomy and Neuroscience
How is the immunological T cell memory generated?	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Howden laboratory: Molecular epidemiology, genomics and pathogenesis of antimicrobial resistant bacteria	Head of Laboratory \| Director of MDU Professor Ben Howden	Microbiology and Immunology
Hoyer laboratory: Translational neuroscience	Head of Laboratory Head of Department Deputy Head, School of Biomedical Sciences Professor Daniel Hoyer	Pharmacology and Therapeutics
Human brain networks processing respiratory sensations	Project Leader Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Identifying the mechanisms of immune cell development in peripheral tissues	Project Leader Dr Laura Mackay	Microbiology and Immunology
Imaging effector and memory T cell responses in the skin following Herpes Simplex Virus-1 infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Imaging the priming of CD8 Killer T cell responses to Herpes Simplex Virus-1 skin infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Improved vaccines by targeting to dendritic cells	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Improving recovery of injured visceral nerves and their spinal control centres	Project Leader Professor Janet Keast	Anatomy and Neuroscience
Influenza A virus PB1-F2 Protein: a putative virulence factor and initiator of inflammation	Project Leader Dr Julie McAuley	Microbiology and Immunology
Influenza–specific ADCC: Role in a universal flu vaccine?	Project Leader Professor Stephen Kent	Microbiology and Immunology
Innate immunity and neural injury	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Innate T cell recognition and development	Project Leader Dr Daniel Pellicci	Microbiology and Immunology
Innovative approaches to prepare synthetic, partially synthetic and natural product-based vaccines	Project Leader Professor David Jackson	Microbiology and Immunology
Interplay of sex differentiation and metabolism	Project Leader Associate Professor Dagmar Wilhelm	Anatomy and Neuroscience
Intraepithelial T cells in anti-viral immunity	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
Intravital imaging of T cell responses in the brain during cerebral malaria infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Investigation of HSV latency and reactivation	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
Is the “shed” form of Sez-6 proteins responsible for their synapse-promoting effects?	Head of Laboratory Dr Jenny Gunnersen Project Leader Dr Kathryn Munro	Anatomy and Neuroscience
Ivanusic laboratory: Pain and sensory mechanisms	Head of Laboratory Dr Jason Ivanusic	Anatomy and Neuroscience
Jackson laboratory: Synthetic vaccine design	Head of Laboratory Professor David Jackson	Microbiology and Immunology
Kedzierska laboratory: Immunity to pandemic and newly emerged influenza viruses	Head of Laboratory Associate Professor Katherine Kedzierska	Microbiology and Immunology
Kent laboratory: HIV vaccines; immune responses to HIV-1; immunotherapy	Head of Laboratory Professor Stephen Kent	Microbiology and Immunology
Kilpatrick laboratory: Neuroimmunology of Multiple Sclerosis	Head of Laboratory Professor Trevor Kilpatrick	Anatomy and Neuroscience
Klebsiella pneumoniae	Project Leader Professor Dick Strugnell	Microbiology and Immunology
Lawson laboratory: Neurodegenerative disease caused by prions	Head of Laboratory Associate Professor Vicki Lawson	Microbiology and Immunology
Lipopeptide-based adjuvanting systems	Project Leader Professor David Jackson	Microbiology and Immunology
Lung Disease Research Laboratory	Head of Laboratory Professor Gary P Anderson	Pharmacology and Therapeutics
Mackay (F) laboratory: B lymphocytes, BAFF, autoimmunity and cancer	Head of Laboratory Head of School of Biomedical Sciences Professor Fabienne Mackay	Microbiology and Immunology
Mackay (L) laboratory: Tissue-resident memory T cells; lymphocyte differentiation; peripheral immunity	Senior Lecturer & NHMRC Career Development Fellow, HHMI-Gates International Research Scholar Dr Laura Mackay	Microbiology and Immunology
Mackenzie laboratory: Intracellular virus replication and innate immunity	Head of Laboratory Professor Jason Mackenzie	Microbiology and Immunology
Malaria and Tissue Resident Memory T cells (TRM) in the liver	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Mazzone laboratory: Respiratory Sensory Neuroscience	Head of Research Group Associate Professor Stuart Mazzone	Anatomy and Neuroscience
McCluskey laboratory: Role of MAIT cells in health and disease	Head of Laboratory, Redmond Barry Distinguished Professor Professor James McCluskey	Microbiology and Immunology
McConville laboratory: Molecular microbiology	Head of Laboratory Professor Malcolm McConville	Biochemistry and Molecular Biology
Mechanisms of growth factor signalling	Project Leader Dr Simon Murray	Anatomy and Neuroscience
Mechanisms underlying early generation of human T cell memory	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Memory T cell responses in the lung during virus infection	Project Leader Dr Linda Wakim	Microbiology and Immunology
Mintern laboratory: Vaccine biology	Head of Laboratory Dr Justine Mintern	Biochemistry and Molecular Biology
Modelling sensory neuron-epithelial interactions	Project Leader Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Molecular and cellular analysis of mammalian ovary development and disease	Project Leader Associate Professor Dagmar Wilhelm	Anatomy and Neuroscience
Molecular Mechanisms of Disease
Molecular mechanisms that contribute to bone marrow pain	Head of Laboratory Dr Jason Ivanusic	Anatomy and Neuroscience
Mueller laboratory: Adaptive immune responses to infection, lymphoid stromal cells, and imaging the immune system	Head of Laboratory Associate Professor Scott Mueller	Microbiology and Immunology
Murray & Xiao laboratory: Neurotrophin and myelin	Joint Heads of Laboratory Dr Simon Murray & Dr Junhua Xiao	Anatomy and Neuroscience
Mycobacterium ulcerans	Project Leader Professor TIm Stinear	Microbiology and Immunology
Nanoparticle HIV vaccines	Project Leader Professor Stephen Kent	Microbiology and Immunology
Nanoparticle Modulation of Mast Cell Function	Project Leader Dr Graham Mackay	Pharmacology and Therapeutics
Newton laboratory: Virulence strategies of intracellular bacterial pathogens	Head of Laboratory Dr Hayley Newton	Microbiology and Immunology
NK cell receptor biology	Project Leader Professor Andrew Brooks	Microbiology and Immunology
NKT cells, MAIT cells, CD1-restricted T cells and HIV	Project Leader Professor Stephen Kent	Microbiology and Immunology
Non-classical MHC and Class 1-like molecules	Project Leader Professor Andrew Brooks	Microbiology and Immunology
Norovirus replication and innate immunity	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
Novel Mast Cell-Derived Mediators	Project Leader Dr Graham Mackay	Pharmacology and Therapeutics
Oxidative stress and neural injury	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Pain management using ultrasound-guided local anaesthetic techniques	Head of Laboratory Dr Jason Ivanusic	Anatomy and Neuroscience
Parker Laboratory: Structural biology and computational drug design	Head of Laboratory and Director, Bio21 Institute Professor Michael Parker	Biochemistry and Molecular Biology
Passive antibody immunity for use in combination microbicides	Project Leader Professor Damian Purcell	Microbiology and Immunology
Post-translational control of cell fate decisions	Project Leader Associate Professor Dagmar Wilhelm	Anatomy and Neuroscience
Potential of cell therapy to treat Hirschsprung’s disease	Head of Laboratory Professor Heather Young Project Leader Dr Lincon Stamp	Anatomy and Neuroscience
Prognostic biomarker and therapeutic target discovery in stroke	Project Leader Dr Jonathon Mangum	Pharmacology and Therapeutics
Proliferation of enteric neuron precursors	Head of Laboratory Professor Heather Young Project Leader Professor Heather Young	Anatomy and Neuroscience
Purcell laboratory: Viral RNA elements, regulation of HIV replication, HIV antibody vaccine	Head of Laboratory Professor Damian Purcell	Microbiology and Immunology
Ralph laboratory: Drug targets and gene regulation in Plasmodium falciparum	Head of Laboratory Dr Stuart Ralph	Biochemistry and Molecular Biology
Reading laboratory: Innate immune detection and response to respiratory virus infections	Head of Laboratory Associate Professor Patrick Reading	Microbiology and Immunology
Regulation of Mast Cell Activation	Project Leader Dr Graham Mackay	Pharmacology and Therapeutics
Reid laboratory: Proteomics and lipidomics in health and disease	Head of Laboratory Professor Gavin E. Reid	Biochemistry and Molecular Biology
Restoring immunocompetency in Chronic Lymphocytic Leukemia	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
Risk genes for neuropsychiatric disorders	Project Leader Dr Mike Clark	Anatomy and Neuroscience
RNA mediated control of HIV-1 gene expression	Project Leader Professor Damian Purcell	Microbiology and Immunology
Robins-Browne laboratory: Medical bacteriology, pathogenesis, bacterial genetics, therapeutics	Head of Laboratory Professor Roy Robins-Browne	Microbiology and Immunology
Role of cellular lipids during Flavivirus replication	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
Role of innate signals in inducing protective T cell immunity	Project Leader Associate Professor Sammy Bedoui	Microbiology and Immunology
Role of long noncoding RNAs in neurological disorders	Project Leader Dr Mike Clark	Anatomy and Neuroscience
Rotavirus induction and evasion of innate immunity	Project Leader Associate Professor Barbara Coulson	Microbiology and Immunology
Rotavirus modulation of type 1 diabetes development	Project Leader Associate Professor Barbara Coulson	Microbiology and Immunology
Rotavirus-cell binding and entry	Project Leader Associate Professor Barbara Coulson	Microbiology and Immunology
Salmonella Typhimurium	Project Leader Professor Dick Strugnell	Microbiology and Immunology
Saunders laboratory: Developmental neuroscience and neurotrauma	Head of Laboratory Professor Norman Saunders	Pharmacology and Therapeutics
Self-tolerance: Interactions between thymic stroma and dendritic cells	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Simmons laboratory: Dengue; pathogenesis, epidemiology, therapeutics, entomology	Head of Laboratory Professor Cam Simmons	Microbiology and Immunology
Soluble barriers to influenza virus infection	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
Staphylococcus aureus & Enterococcus faecium	Project Leader Professor Tim Stinear	Microbiology and Immunology
Staphylococcus aureus and Staphylococcus epidermidis	Project Leader Professor Ben Howden	Microbiology and Immunology
Stojanovski laboratory: Mitochondrial biogenesis in health and disease	Head of Laboratory Dr Diana Stojanovski	Biochemistry and Molecular Biology
Stroke	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Stroud laboratory: Mitochondrial Systems Biology	Head of Research Group Dr David Stroud	Biochemistry and Molecular Biology
Strugnell laboratory: Bacterial pathogenesis and host responses	Head of Laboratory Professor Dick Strugnell	Microbiology and Immunology
T cells in peripheral immunity	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
The GDNF family, peripheral nerve regeneration and pain	Project Leader Professor Janet Keast	Anatomy and Neuroscience
The influence of neurotrophin signalling upon the generation of myelin	Project Leader Dr Simon Murray	Anatomy and Neuroscience
The innate immune system in the respiratory tract	Project Leader Professor David Jackson	Microbiology and Immunology
The mechanisms of viral escape in murine and human influenza infection	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
The role of CD4+ T cells in viral infections	Project Leader Professor Andrew Brooks	Microbiology and Immunology
The Role of CXCR7 in Tissue Fibrosis	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
The role of glia in inner retinal changes during retinal degeneration	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
The role of glial cells in retinal vascular disease	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
The role of innate immune cells in protection and pathology during influenza virus infection	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
The role of microglia in age-related macular degeneration	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
The role of non-coding RNA in embryonic development	Project Leader Associate Professor Dagmar Wilhelm	Anatomy and Neuroscience
The role of resident memory T cells in barrier immunity and autoimmune disease	Project Leader Dr Laura Mackay	Microbiology and Immunology
The unique features of visceral pain	Project Leader Professor Janet Keast	Anatomy and Neuroscience
Tracking phenotypically and functionally distinct T cell subsets via T cell repertoire diversity	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Transcriptional profiling of sensory neurons	Project Leader Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Traumatic brain injury	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Uncovering the interplay between innate immunity and the blood brain barrier in disorders of the CNS	Project Leader Professor Christine Wells	Anatomy and Neuroscience
Understanding neuro-urothelial communication	Project Leader Professor Janet Keast	Anatomy and Neuroscience
Understanding the interaction between microbiota and T cell immunity	Project Leader Associate Professor Sammy Bedoui	Microbiology and Immunology
Understanding the molecular basis of myelin repair	Project Leader Dr Junhua Xiao	Anatomy and Neuroscience
Understanding the regulation of tissue-resident memory T cell development	Project Leader Dr Laura Mackay	Microbiology and Immunology
Understanding ‘universal’ influenza-specific CD8+ T cell responses	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Using biochemical approaches to investigating the trafficking and mechanism of action of the antiviral molecule, IFITM3	Project Leader Dr Linda Wakim	Microbiology and Immunology
Vaccination against liver-stage Plasmodium for malaria prevention	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
van Driel laboratory: Immune responses to pathogens	Head of Laboratory Professor Ian van Driel	Biochemistry and Molecular Biology
Villadangos laboratory: Antigen presenting cells & molecules that initiate T cell immunity against pathogens and cancer	Head of Laboratory Professor Jose Villadangos	Microbiology and Immunology
Viral interactions with the innate immune system	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
Viral tracing to identify central projections and pathways for sensory neurons that innervate bone	Head of Laboratory Dr Jason Ivanusic	Anatomy and Neuroscience
Visualization and formation West Nile Virus replication complexes	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
Wakim laboratory: Antiviral molecules, mucosal immunology, influenza virus, tissue resident memory T cells	Head of Laboratory Dr Linda Wakim	Microbiology and Immunology
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Physiology
West Nile Virus replication and cellular stress responses	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
What is the function of Sez6L2 in the forebrain?	Head of Laboratory Dr Jenny Gunnersen Project Leader Dr Kathryn Munro	Anatomy and Neuroscience
Wilhelm laboratory: Sex determination and disorders of sex development	Head of Laboratory Associate Professor Dagmar Wilhelm	Anatomy and Neuroscience
Wolbachia to stop dengue transmission in Vietnam and Indonesia	Project Leader Professor Cameron Simmons	Microbiology and Immunology
Young laboratory: Development of the enteric nervous system	Head of Laboratory Professor Heather Young	Anatomy and Neuroscience

182

Biomedical Neuroscience

Groups / Projects	Research Lead	Dept / Centre
Applications of Nanopore sequencing	Project Leader Dr Mike Clark	Anatomy and Neuroscience
Autologous stem cell therapies in Australia	Project Leader Associate Professor Megan Munsie	Anatomy and Neuroscience
Biomedical Neuroscience
Blood Atlas: Understanding cell state and differentiation using genomics data from blood cells	Project Leader Professor Christine Wells	Anatomy and Neuroscience
Brain networks processing respiratory sensations	Project Leader Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Brock laboratory: Autonomic and sensory neuroscience	Head of Laboratory Associate Professor James Brock	Anatomy and Neuroscience
Can drug-like mimetics of BDNF promote remyelination after injury?	Project Leader Dr Junhua Xiao	Anatomy and Neuroscience
Cappai laboratory: Neurodegeneration and Brain Injury	Head of Laboratory Professor Roberto Cappai	Pharmacology and Therapeutics
Cell state and cell fate: Systems biology approaches to understanding cell identity	Project Leader Professor Christine Wells	Anatomy and Neuroscience
Clark laboratory: Transcriptomics and Neurogenetics	Head of Laboratory Dr Mike Clark	Anatomy and Neuroscience
Contemplating stem cells in society	Project Leader Dr Claire Tanner	Anatomy and Neuroscience
Crack laboratory: Neuropharmacology	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Crouch laboratory: Neurodegenerative disease	Head of Laboratory Dr Peter Crouch	Pharmacology and Therapeutics
De Iongh laboratory: Ocular development laboratory	Head of Laboratory Associate Professor Robb de Iongh	Anatomy and Neuroscience
Dental morphology	Project Leader Dr Varsha Pilbrow	Anatomy and Neuroscience
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Head of Laboratory Professor Matthew Watt	Physiology
E3 Ubiquitin Ligase in skeletal muscle	Head of Laboratory Associate Professor Paul Gregorevic	Physiology
Factors that accelerate photoreceptor death: The role of purines	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
Fletcher laboratory: Visual neuroscience	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
Furness laboratory: Digestive physiology and nutrition	Head of Laboratory Professor John Furness	Anatomy and Neuroscience
Glial cells as a source of progenitor cells in degenerative disease	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
Gooley laboratory: Structural biology of disease	Head of Laboratory Associate Professor Paul Gooley	Biochemistry and Molecular Biology
Gregorevic laboratory: Muscle Research and Therapeutics	Head of Laboratory Associate Professor Paul Gregorevic	Physiology
Griffin laboratory: Functional and mis-functional protein-protein interactions	Head of Laboratory Dr Michael Griffin	Biochemistry and Molecular Biology
Growth factors and peptide mimetics	Project Leader Dr Susan Northfield	Pharmacology and Therapeutics
Gunnersen laboratory: Neuron development and plasticity	Head of Laboratory Dr Jenny Gunnersen	Anatomy and Neuroscience
Hatters laboratory: Protein misfolding and proteostasis in neurodegenerative diseases	Head of Laboratory Associate Professor Danny Hatters	Biochemistry and Molecular Biology
How BDNF signalling controls myelination?	Project Leader Dr Simon Murray	Anatomy and Neuroscience
How does GM-CSF prevent brain damage after traumatic injury?	Head of Laboratory Dr Jenny Gunnersen Project Leader Dr Sandy Shultz	Anatomy and Neuroscience
How sensory signals are detected: Structure function relationships in peripheral sensory nerve terminals	Project Leader Associate Professor James Brock	Anatomy and Neuroscience
Hoyer laboratory: Translational neuroscience	Head of Laboratory Head of Department Deputy Head, School of Biomedical Sciences Professor Daniel Hoyer	Pharmacology and Therapeutics
Hughes laboratory: Drug design	Head of Laboratory Associate Professor Tony Hughes	Pharmacology and Therapeutics
Human brain networks processing respiratory sensations	Project Leader Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Improving bladder health after spinal cord injury	Project Leader Associate Professor James Brock	Anatomy and Neuroscience
Improving recovery of injured visceral nerves and their spinal control centres	Project Leader Professor Janet Keast	Anatomy and Neuroscience
Innate immunity and neural injury	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Is the “shed” form of Sez-6 proteins responsible for their synapse-promoting effects?	Head of Laboratory Dr Jenny Gunnersen Project Leader Dr Kathryn Munro	Anatomy and Neuroscience
Ivanusic laboratory: Pain and sensory mechanisms	Head of Laboratory Dr Jason Ivanusic	Anatomy and Neuroscience
Kilpatrick laboratory: Neuroimmunology of Multiple Sclerosis	Head of Laboratory Professor Trevor Kilpatrick	Anatomy and Neuroscience
Live cell imaging of neural crest cell migration along the developing gut	Head of Laboratory Professor Heather Young Head of Laboratory Professor Heather Young	Anatomy and Neuroscience
Mazzone laboratory: Respiratory Sensory Neuroscience	Head of Research Group Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Mechanisms of growth factor signalling	Project Leader Dr Simon Murray	Anatomy and Neuroscience
Modelling sensory neuron-epithelial interactions	Project Leader Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Modulation of intestinal inflammation through nerve stimulation	Project Supervisor Dr Martin Stebbing	Anatomy and Neuroscience
Molecular mechanisms that contribute to bone marrow pain	Head of Laboratory Dr Jason Ivanusic	Anatomy and Neuroscience
Murray & Xiao laboratory: Neurotrophin and myelin	Joint Heads of Laboratory Dr Simon Murray & Dr Junhua Xiao	Anatomy and Neuroscience
Nerve pathways responding to and controlling inflammation in the intestine	Project Supervisor Dr Martin Stebbing	Anatomy and Neuroscience
Novel drugs and receptors for targeting neural control of digestive system functtion	Project Supervisor Dr Rachel McQuade	Anatomy and Neuroscience
Novel technique to determine the pKA of clonidine at prejunctional α2-adrenoceptors in sympathetic transmission	Project Leader Professor James Angus	Pharmacology and Therapeutics
Oxidative stress and neural injury	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Pain management using ultrasound-guided local anaesthetic techniques	Head of Laboratory Dr Jason Ivanusic	Anatomy and Neuroscience
Parker Laboratory: Structural biology and computational drug design	Head of Laboratory and Director, Bio21 Institute Professor Michael Parker	Biochemistry and Molecular Biology
Patient voices: An analysis of patients’ information-based priorities and needs	Project Leader Associate Professor Megan Munsie	Anatomy and Neuroscience
Pilbrow laboratory: Physical (biological) anthropology	Head of Laboratory Dr Varsha Pilbrow	Anatomy and Neuroscience
Potential of cell therapy to treat Hirschsprung’s disease	Head of Laboratory Professor Heather Young Project Leader Dr Lincon Stamp	Anatomy and Neuroscience
Prognostic biomarker and therapeutic target discovery in stroke	Project Leader Dr Jonathon Mangum	Pharmacology and Therapeutics
Proliferation of enteric neuron precursors	Head of Laboratory Professor Heather Young Project Leader Professor Heather Young	Anatomy and Neuroscience
Relaxin family peptide hormones	Project Leader Associate Professor Tony Hughes	Pharmacology and Therapeutics
Risk genes for neuropsychiatric disorders	Project Leader Dr Mike Clark	Anatomy and Neuroscience
Role of long noncoding RNAs in neurological disorders	Project Leader Dr Mike Clark	Anatomy and Neuroscience
Rouiller laboratory: Understanding how molecular machines function through cryo-electron microscopy	Associate Professor Isabelle Rouiller	Biochemistry and Molecular Biology
Saunders laboratory: Developmental neuroscience and neurotrauma	Head of Laboratory Professor Norman Saunders	Pharmacology and Therapeutics
Skeletal morphology	Project Leader Dr Varsha Pilbrow	Anatomy and Neuroscience
Stroke	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
The gastrointestinal complications of Parkinson's Disease	Project Supervisor Dr Shanti Diwakarla	Anatomy and Neuroscience
The GDNF family, peripheral nerve regeneration and pain	Project Leader Professor Janet Keast	Anatomy and Neuroscience
The influence of neurotrophin signalling upon the generation of myelin	Project Leader Dr Simon Murray	Anatomy and Neuroscience
The link between cardiovascular disease and neurodegeneration – focus on Alzheimer’s disease	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
The role of glia in inner retinal changes during retinal degeneration	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
The role of glial cells in retinal vascular disease	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
The role of microglia in age-related macular degeneration	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
The Stemformatics Stem Cell Atlas	Project Leader Professor Christine Wells	Anatomy and Neuroscience
The taxonomy of enteroendocrine cells and their innervation	Project Supervisor Professor John B Furness	Anatomy and Neuroscience
The unique features of visceral pain	Project Leader Professor Janet Keast	Anatomy and Neuroscience
Transcriptional profiling of sensory neurons	Project Leader Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Traumatic brain injury	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Understanding neuro-urothelial communication	Project Leader Professor Janet Keast	Anatomy and Neuroscience
Understanding the molecular basis of myelin repair	Project Leader Dr Junhua Xiao	Anatomy and Neuroscience
Viral tracing to identify central projections and pathways for sensory neurons that innervate bone	Head of Laboratory Dr Jason Ivanusic	Anatomy and Neuroscience
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Physiology
What is the function of Sez6L2 in the forebrain?	Head of Laboratory Dr Jenny Gunnersen Project Leader Dr Kathryn Munro	Anatomy and Neuroscience
Young laboratory: Development of the enteric nervous system	Head of Laboratory Professor Heather Young	Anatomy and Neuroscience

Stem Cells

Groups / Projects	Research Lead	Dept / Centre
Analysing genetic roles of RNA-binding proteins and alternative splicing in Drosophila stem cells	Project Leader Professor Gary Hime	Anatomy and Neuroscience
Autologous stem cell therapies in Australia	Project Leader Associate Professor Megan Munsie	Anatomy and Neuroscience
Blood Atlas: Understanding cell state and differentiation using genomics data from blood cells	Project Leader Professor Christine Wells	Anatomy and Neuroscience
Cell state and cell fate: Systems biology approaches to understanding cell identity	Project Leader Professor Christine Wells	Anatomy and Neuroscience
Cellular trafficking and male fertility	Project Leader Professor Gary Hime	Anatomy and Neuroscience
Clark laboratory: Transcriptomics and Neurogenetics	Head of Laboratory Dr Mike Clark	Anatomy and Neuroscience
Contemplating stem cells in society	Project Leader Dr Claire Tanner	Anatomy and Neuroscience
EMT regulators in intestinal and germline stem cells	Project Leader Professor Gary Hime	Anatomy and Neuroscience
Hime laboratory: Stem cell genetics	Head of Laboratory Professor Gary Hime	Anatomy and Neuroscience
Molecular and cellular analysis of mammalian ovary development and disease	Project Leader Associate Professor Dagmar Wilhelm	Anatomy and Neuroscience
Munsie laboratory: Ethical, legal and social implications of stem cell research	Head of Laboratory Associate Professor Megan Munsie	Anatomy and Neuroscience
Novel regulators of germline stem cells	Project Leader Professor Gary HIme	Anatomy and Neuroscience
Patient voices: An analysis of patients’ information-based priorities and needs	Project Leader Associate Professor Megan Munsie	Anatomy and Neuroscience
Risk genes for neuropsychiatric disorders	Project Leader Dr Mike Clark	Anatomy and Neuroscience
Stem Cells
The Stemformatics Stem Cell Atlas	Project Leader Professor Christine Wells	Anatomy and Neuroscience
Transcriptional regulation of intestinal organoid differentiation	Project Leader Professor Gary Hime	Anatomy and Neuroscience
Wells laboratory: Stem cell systems	Head of Laboratory Professor Christine Wells	Anatomy and Neuroscience
Wilhelm laboratory: Sex determination and disorders of sex development	Head of Laboratory Associate Professor Dagmar Wilhelm	Anatomy and Neuroscience

Systems Biology

Groups / Projects	Research Lead	Dept / Centre
Application of genomics to public health and clinical microbiology	Project Leader Professor Ben Howden	Microbiology and Immunology
Applications of Nanopore sequencing	Project Leader Dr Mike Clark	Anatomy and Neuroscience
Australian Venom Research Unit	Head of Unit Dr David Williams	Pharmacology and Therapeutics
Blood Atlas: Understanding cell state and differentiation using genomics data from blood cells	Project Leader Professor Christine Wells	Anatomy and Neuroscience
Bo&MeRanG Research Projects	Melbourne Coordinator Dr Marie Greyer
Cell state and cell fate: Systems biology approaches to understanding cell identity	Project Leader Professor Christine Wells	Anatomy and Neuroscience
Clinical Proteomics	Project Leader Dr Jonathon Mangum	Pharmacology and Therapeutics
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Head of Laboratory Professor Matthew Watt	Physiology
Enterococcus faecium	Project Leader Professor Ben Howden	Microbiology and Immunology
Hatters laboratory: Protein misfolding and proteostasis in neurodegenerative diseases	Head of Laboratory Associate Professor Danny Hatters	Biochemistry and Molecular Biology
Holt laboratory: Pathogen genomics and bioinformatics	Head of Laboratory A/Prof Kathryn Holt	Biochemistry and Molecular Biology
Howden laboratory: Molecular epidemiology, genomics and pathogenesis of antimicrobial resistant bacteria	Head of Laboratory \| Director of MDU Professor Ben Howden	Microbiology and Immunology
Ivanusic laboratory: Pain and sensory mechanisms	Head of Laboratory Dr Jason Ivanusic	Anatomy and Neuroscience
Molecular mechanisms that contribute to bone marrow pain	Head of Laboratory Dr Jason Ivanusic	Anatomy and Neuroscience
Mycobacterium ulcerans	Project Leader Professor TIm Stinear	Microbiology and Immunology
Pain management using ultrasound-guided local anaesthetic techniques	Head of Laboratory Dr Jason Ivanusic	Anatomy and Neuroscience
Risk genes for neuropsychiatric disorders	Project Leader Dr Mike Clark	Anatomy and Neuroscience
Role of long noncoding RNAs in neurological disorders	Project Leader Dr Mike Clark	Anatomy and Neuroscience
Staphylococcus aureus & Enterococcus faecium	Project Leader Professor Tim Stinear	Microbiology and Immunology
Staphylococcus aureus and Staphylococcus epidermidis	Project Leader Professor Ben Howden	Microbiology and Immunology
Stinear laboratory: Bacterial pathogenomics	Head of Laboratory Professor Tim Stinear	Microbiology and Immunology
Stroud laboratory: Mitochondrial Systems Biology	Head of Research Group Dr David Stroud	Biochemistry and Molecular Biology
Systems Biology
The Cardiovascular Pharmacology of Snake Venoms From Papua New Guinea and Australia	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
The Stemformatics Stem Cell Atlas	Project Leader Professor Christine Wells	Anatomy and Neuroscience
The Treatment of Papuan Taipan Envenoming in Papua New Guinea	Project Leader Dr David Williams	Pharmacology and Therapeutics
Viral tracing to identify central projections and pathways for sensory neurons that innervate bone	Head of Laboratory Dr Jason Ivanusic	Anatomy and Neuroscience
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Physiology
Wells laboratory: Stem cell systems	Head of Laboratory Professor Christine Wells	Anatomy and Neuroscience

Therapeutics & Translation

Groups / Projects	Research Lead	Dept / Centre
A universal vaccine against influenza A	Project Leader Professor David Jackson	Microbiology and Immunology
Ascher laboratory: Structural biology and bioinformatics	Head of Laboratory Dr David Ascher	Biochemistry and Molecular Biology
Australian bite and sting trends: Australian Venomous Injury Project (AVIP)	Project Leader Dr Ronelle Welton	Pharmacology and Therapeutics
Australian Venom Research Unit	Head of Unit Dr David Williams	Pharmacology and Therapeutics
Autologous stem cell therapies in Australia	Project Leader Associate Professor Megan Munsie	Anatomy and Neuroscience
Biolpolymer-based vaccine delivery systems	Project Leader Professor David Jackson	Microbiology and Immunology
Bo&MeRanG Research Projects	Melbourne Coordinator Dr Marie Greyer
Can drug-like mimetics of BDNF promote remyelination after injury?	Project Leader Dr Junhua Xiao	Anatomy and Neuroscience
Contemplating stem cells in society	Project Leader Dr Claire Tanner	Anatomy and Neuroscience
Crack laboratory: Neuropharmacology	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Developing new therapies for Systemic Lupus Erythematosus	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
Development of a self-adjuvanting vaccine for enterotoxigenic Escherichia coli (ETEC)	Project Leader Professor David Jackson	Microbiology and Immunology
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Head of Laboratory Professor Matthew Watt	Physiology
E3 Ubiquitin Ligase in skeletal muscle	Head of Laboratory Associate Professor Paul Gregorevic	Physiology
Edgington-Mitchell laboratory: Protease Pathophysiology	Head of Research Group Dr Laura Edgington-Mitchell	Biochemistry and Molecular Biology
Endothelin pharmacology in the setting of pulmonary hypertension	Project Leader Professor James Angus	Pharmacology and Therapeutics
Furness laboratory: Digestive physiology and nutrition	Head of Laboratory Professor John Furness	Anatomy and Neuroscience
Gleeson laboratory: Membrane trafficking and protein sorting in health and disease and development of new therapeutics	Head of Laboratory Professor Paul Gleeson	Biochemistry and Molecular Biology
Gooley laboratory: Structural biology of disease	Head of Laboratory Associate Professor Paul Gooley	Biochemistry and Molecular Biology
Gregorevic laboratory: Muscle Research and Therapeutics	Head of Laboratory Associate Professor Paul Gregorevic	Physiology
Growth factors and peptide mimetics	Project Leader Dr Susan Northfield	Pharmacology and Therapeutics
How BDNF signalling controls myelination?	Project Leader Dr Simon Murray	Anatomy and Neuroscience
Hughes laboratory: Drug design	Head of Laboratory Associate Professor Tony Hughes	Pharmacology and Therapeutics
Innovative approaches to prepare synthetic, partially synthetic and natural product-based vaccines	Project Leader Professor David Jackson	Microbiology and Immunology
Ivanusic laboratory: Pain and sensory mechanisms	Head of Laboratory Dr Jason Ivanusic	Anatomy and Neuroscience
Jackson laboratory: Synthetic vaccine design	Head of Laboratory Professor David Jackson	Microbiology and Immunology
Lew laboratory: Theoretical and empirical pharmacology	Head of Laboratory Dr Michael Lew	Pharmacology and Therapeutics
Lipopeptide-based adjuvanting systems	Project Leader Professor David Jackson	Microbiology and Immunology
Mangum Lab: Translational Proteomics	Head of Laboratory Dr Jonathan Mangum	Pharmacology and Therapeutics
McConville laboratory: Molecular microbiology	Head of Laboratory Professor Malcolm McConville	Biochemistry and Molecular Biology
Mechanisms of growth factor signalling	Project Leader Dr Simon Murray	Anatomy and Neuroscience
Molecular mechanisms of drug resistance in cancer	Project Leader Dr Jonathon Mangum	Pharmacology and Therapeutics
Molecular mechanisms that contribute to bone marrow pain	Head of Laboratory Dr Jason Ivanusic	Anatomy and Neuroscience
Munsie laboratory: Ethical, legal and social implications of stem cell research	Head of Laboratory Associate Professor Megan Munsie	Anatomy and Neuroscience
Murray & Xiao laboratory: Neurotrophin and myelin	Joint Heads of Laboratory Dr Simon Murray & Dr Junhua Xiao	Anatomy and Neuroscience
Pain management using ultrasound-guided local anaesthetic techniques	Head of Laboratory Dr Jason Ivanusic	Anatomy and Neuroscience
Patient voices: An analysis of patients’ information-based priorities and needs	Project Leader Associate Professor Megan Munsie	Anatomy and Neuroscience
Preclinical pharmacology – cardiovascular efficacy and safety R&D	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
Prognostic biomarker and therapeutic target discovery in stroke	Project Leader Dr Jonathon Mangum	Pharmacology and Therapeutics
Ralph laboratory: Drug targets and gene regulation in Plasmodium falciparum	Head of Laboratory Dr Stuart Ralph	Biochemistry and Molecular Biology
Relaxin family peptide hormones	Project Leader Associate Professor Tony Hughes	Pharmacology and Therapeutics
Restoring immunocompetency in Chronic Lymphocytic Leukemia	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
Stewart Laboratory: Mechanopharmacology	Head of Laboratory Professor Alastair Stewart	Pharmacology and Therapeutics
The Cardiovascular Pharmacology of Snake Venoms From Papua New Guinea and Australia	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
The influence of neurotrophin signalling upon the generation of myelin	Project Leader Dr Simon Murray	Anatomy and Neuroscience
The link between cardiovascular disease and neurodegeneration – focus on Alzheimer’s disease	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
The Role of CXCR7 in Tissue Fibrosis	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
The Treatment of Papuan Taipan Envenoming in Papua New Guinea	Project Leader Dr David Williams	Pharmacology and Therapeutics
Therapeutics & Translation
Tilley laboratory: Measuring and modelling malaria parasites to develop new antimalarials	Head of Laboratory, ARC Australian Laureate Fellow Professor Leann Tilley	Biochemistry and Molecular Biology
Trovafloxacin – an antibiotic with additional properties	Project Leader Professor James Angus	Pharmacology and Therapeutics
Understanding the molecular basis of myelin repair	Project Leader Dr Junhua Xiao	Anatomy and Neuroscience
Velkov laboratory: Antiinfective pharmacology	Head of Laboratory Associate Professor Tony Velkov	Pharmacology and Therapeutics
Viral tracing to identify central projections and pathways for sensory neurons that innervate bone	Head of Laboratory Dr Jason Ivanusic	Anatomy and Neuroscience
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Physiology
Wolbachia to stop dengue transmission in Vietnam and Indonesia	Project Leader Professor Cameron Simmons	Microbiology and Immunology
Wright laboratory: Cardiovascular Therapeutics Unit	Head of Laboratory Associate Professor Christine E Wright	Pharmacology and Therapeutics

Scholarship of Teaching and Learning

Groups / Projects	Research Lead	Dept / Centre
Scholarship of Teaching and Learning
Verkade group: Molecular Biology Education Scholarship	Head of Group: Associate Professor Heather Verkade	Biochemistry and Molecular Biology