Biomedical Projects by Theme

Cancer in Biomedicine

Groups / Projects	Research Lead	Dept / Centre
Analysing and Interpreting protein structures	Dr David Ascher	Biochemistry and Molecular Biology
Analysing genetic roles of RNA-binding proteins and alternative splicing in Drosophila stem cells	Professor Gary Hime	Anatomy and Neuroscience
Ascher laboratory: Structural biology and bioinformatics	Dr David Ascher	Biochemistry and Molecular Biology
Biochemical and structural basis of the tumour suppression mechanism of CSK-homologous kinase	Associate Professor Heung-Chin Cheng	Biochemistry and Molecular Biology
Bo&MeRanG Research Projects	Dr Marie Greyer
Bogoyevitch laboratory: Regulatory biology	Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Cancer in Biomedicine
Cheng laboratory: Molecular enzymology of protein kinases and phosphatases involved in human diseases	Associate Professor Heung-Chin Cheng	Biochemistry and Molecular Biology
Comprehensive lipidome profiling to identify functional biomarkers of colorectal cancer metastasis	Professor Gavin E. Reid	Biochemistry and Molecular Biology
Contribution of proteases to oral cancer pain and metastasis	Dr Laura Edgington-Mitchell	Biochemistry and Molecular Biology
Designing better drugs	Dr David Ascher	Biochemistry and Molecular Biology
Development of Novel Chemical Tools to Measure Protease Activation	Dr Laura Edgington-Mitchell	Biochemistry and Molecular Biology
Development of self-reporting fluorescent chemosensor peptide substrates as molecular sensors	Associate Professor Heung-Chin Cheng	Biochemistry and Molecular Biology
EMT regulators in intestinal and germline stem cells	Professor Gary Hime	Anatomy and Neuroscience
Hime laboratory: Stem cell genetics	Professor Gary Hime	Anatomy and Neuroscience
Hinde laboratory: Biophysics of Nuclear Organisation	Dr Elizabeth Hinde	Biochemistry and Molecular Biology
Imaging transcription factor DNA target search in a living cell	Dr Elizabeth Hinde	Biochemistry and Molecular Biology
Keeping JNK in its place	Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Mantamadiotis laboratory: Cancer signalling	Dr Theo Mantamadiotis	Microbiology and Immunology
Migration of melanoma cells in the neural crest environment	Dr Sonja McKeown	Anatomy and Neuroscience
Mitochondrial protein biogenesis in mammalian cells	Dr Diana Stojanovski	Biochemistry and Molecular Biology
Novel interventions to treat cardiac cachexia in cancer and chemotherapy	Dr Kate Murphy	Physiology
Novel regulators of germline stem cells	Professor Gary HIme	Anatomy and Neuroscience
Parker Laboratory: Structural biology and computational drug design	Professor Michael Parker	Biochemistry and Molecular Biology
Personalising treatments for genetic diseases	Dr David Ascher	Biochemistry and Molecular Biology
Protein engineering	Dr David Ascher	Biochemistry and Molecular Biology
Protein kinases involved in pathogenesis of Parkinson’s disease	Associate Professor Heung-Chin Cheng	Biochemistry and Molecular Biology
Regulation of telomerase activity in B cells	Dr Asolina Braun	Microbiology and Immunology
Reid laboratory: Proteomics and lipidomics in health and disease	Professor Gavin E. Reid	Biochemistry and Molecular Biology
Restoring immunocompetency in Chronic Lymphocytic Leukemia	Professor Fabienne Mackay	Microbiology and Immunology
Role of chromatin dynamics during the DNA damage response	Dr Elizabeth Hinde	Biochemistry and Molecular Biology
Structural Biology of Cancer	Professor Michael Parker	Biochemistry and Molecular Biology
Structural Biology of Infection	Professor Michael Parker	Biochemistry and Molecular Biology
Structural Neurobiology	Professor Michael Parker	Biochemistry and Molecular Biology
Taylor: Jack Brockhoff Reconstructive Plastic Surgery Research Unit	Professor Ian Taylor	Anatomy and Neuroscience
The gut hormone, ghrelin, its pharmacology, and the possible application of ghrelin receptor agonists in therapy	Professor John B Furness	Anatomy and Neuroscience
Transcriptional regulation of intestinal organoid differentiation	Professor Gary Hime	Anatomy and Neuroscience

Cardio-Respiratory

Groups / Projects	Research Lead	Dept / Centre
Allen laboratory: Central cardiovascular regulation	Professor Andrew Allen	Physiology
Brain networks processing respiratory sensations	Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Delbridge laboratory: Cardiac phenomics	Professor Lea Delbridge	Physiology
Diabetic cardiomyopathy – an epidemic disease	Professor Lea Delbridge	Physiology
Effects of hypertension on renal and hindquarter vascular reactivity in vivo and in vitro	Associate Professor Christine Wright	Pharmacology and Therapeutics
Endothelin pharmacology in the setting of pulmonary hypertension	Professor James Angus	Pharmacology and Therapeutics Research
Hargreaves laboratory: Exercise physiology	Professor Mark Hargreaves	Physiology
Human brain networks processing respiratory sensations	Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Improving the diagnostic outcomes of patients with mitochondrial disease	Dr David Stroud	Biochemistry and Molecular Biology
Lung Disease Research Laboratory	Professor Gary P Anderson	Pharmacology and Therapeutics
Lynch laboratory: Basic and clinical myology	Professor Gordon Lynch	Physiology
Mazzone laboratory: Respiratory Sensory Neuroscience	Associate Professor Stuart Mazzone	Anatomy and Neuroscience Research
Modelling sensory neuron-epithelial interactions	Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Novel technique to determine the pKA of clonidine at prejunctional α2-adrenoceptors in sympathetic transmission	Professor James Angus	Pharmacology and Therapeutics
Pathogenesis of chronic lung disease	Dr Michelle Hansen	Pharmacology and Therapeutics
Preclinical pharmacology – cardiovascular efficacy and safety R&D	Associate Professor Christine Wright	Pharmacology and Therapeutics
Reassessment of α1-adrenoceptor mechanism in artery contraction: role of ATP and pannexin channels	Professor James Angus	Pharmacology and Therapeutics
Steroid hormones and heart failure – sex perspectives	Professor Lea Delbridge	Physiology
Stroud laboratory: Mitochondrial Systems Biology	Dr David Stroud	Biochemistry and Molecular Biology
The cardiovascular pharmacology of snake venoms from Papua New Guinea and Australia	Associate Professor Christine Wright	Pharmacology and Therapeutics
The innate immune system in the respiratory tract	Professor David Jackson	Microbiology and Immunology
The link between cardiovascular disease and neurodegeneration – focus on Alzheimer’s disease	Associate Professor Christine Wright	Pharmacology and Therapeutics
Transcriptional profiling of sensory neurons	Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Trovafloxacin – an antibiotic with additional properties	Professor James Angus	Pharmacology and Therapeutics
Understanding the assembly of mitochondrial machines	Dr David Stroud	Biochemistry and Molecular Biology
Wlodek laboratory: Fetal, postnatal & adult physiology & disease laboratory	Professor Mary Wlodek	Physiology
Wright laboratory: Cardiovascular Therapeutics Unit	Associate Professor Christine E Wright	Pharmacology and Therapeutics

Cell Signalling

Groups / Projects	Research Lead	Dept / Centre
A new function of the cytokine BAFF in dendritic cell maturation: Implications for immunity and cancers	Professor Fabienne Mackay \| Dr Beatriz Garcillan	Microbiology and Immunology
Analysing genetic roles of RNA-binding proteins and alternative splicing in Drosophila stem cells	Professor Gary Hime	Anatomy and Neuroscience
Bedoui laboratory: Innate and adaptive interactions in immunity to infection	Associate Professor Sammy Bedoui	Microbiology and Immunology
Biochemical and structural basis of the tumour suppression mechanism of CSK-homologous kinase	Associate Professor Heung-Chin Cheng	Biochemistry and Molecular Biology
Bo&MeRanG Research Projects	Dr Marie Greyer
Bogoyevitch laboratory: Regulatory biology	Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Brock laboratory: Autonomic and sensory neuroscience	Associate Professor James Brock	Anatomy and Neuroscience
Can drug-like mimetics of BDNF promote remyelination after injury?	Dr Junhua Xiao	Anatomy and Neuroscience
Cell biology of membrane receptors regulating the serum half-life of therapeutic proteins	Professor Paul Gleeson	Biochemistry and Molecular Biology
Cell Signalling
Cellular trafficking and male fertility	Professor Gary Hime	Anatomy and Neuroscience
Cheng laboratory: Molecular enzymology of protein kinases and phosphatases involved in human diseases	Associate Professor Heung-Chin Cheng	Biochemistry and Molecular Biology
Crack laboratory: Neuropharmacology	Associate Professor Peter Crack	Pharmacology and Therapeutics
Defining molecular machinery and cargo sorting along Golgi transport pathways	Professor Paul Gleeson	Biochemistry and Molecular Biology
Delbridge laboratory: Cardiac phenomics	Professor Lea Delbridge	Physiology
Development of self-reporting fluorescent chemosensor peptide substrates as molecular sensors	Associate Professor Heung-Chin Cheng	Biochemistry and Molecular Biology
Diabetic cardiomyopathy – an epidemic disease	Professor Lea Delbridge	Physiology
Discovering and characterizing new genes involved in innate immunity, tissue injury and fibrosis	Professor Christine Wells	Anatomy and Neuroscience
Elucidating the beneficial and harmful elements of the BAFF/APRIL system in multiple sclerosis	Professor Fabienne Mackay \| Dr Beatriz Garcillan	Microbiology and Immunology
EMT regulators in intestinal and germline stem cells	Professor Gary Hime	Anatomy and Neuroscience
Gleeson laboratory: Membrane trafficking and protein sorting in health and disease and development of new therapeutics	Professor Paul Gleeson	Biochemistry and Molecular Biology
Gunnersen laboratory: Neuron development and plasticity	Dr Jenny Gunnersen	Anatomy and Neuroscience
Hime laboratory: Stem cell genetics	Professor Gary Hime	Anatomy and Neuroscience
Hinde laboratory: Biophysics of Nuclear Organisation	Dr Elizabeth Hinde	Biochemistry and Molecular Biology
How BDNF signalling controls myelination?	Dr Simon Murray	Anatomy and Neuroscience
How sensory signals are detected: Structure function relationships in peripheral sensory nerve terminals	Associate Professor James Brock	Anatomy and Neuroscience
Improving bladder health after spinal cord injury	Associate Professor James Brock	Anatomy and Neuroscience
Keast & Osborne laboratory: Neural development, injury and pain	Professor Janet Keast & Dr Peregrine Osborne	Anatomy and Neuroscience
Keeping JNK in its place	Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Mangum laboratory: Proteomics and calcium biology	Dr Jon Mangum	Pharmacology and Therapeutics
Mantamadiotis laboratory: Cancer signalling	Dr Theo Mantamadiotis	Microbiology and Immunology
Mechanisms of growth factor signalling	Dr Simon Murray	Anatomy and Neuroscience
Murray & Xiao laboratory: Neurotrophin and myelin	Dr Simon Murray & Dr Junhua Xiao	Anatomy and Neuroscience
Novel regulators of germline stem cells	Professor Gary HIme	Anatomy and Neuroscience
Protein kinases involved in pathogenesis of Parkinson’s disease	Associate Professor Heung-Chin Cheng	Biochemistry and Molecular Biology
Regulation of telomerase activity in B cells	Dr Asolina Braun	Microbiology and Immunology
Signals for endosomal sorting in development and disease	Professor Paul Gleeson	Biochemistry and Molecular Biology
Steroid hormones and heart failure – sex perspectives	Professor Lea Delbridge	Physiology
The GDNF family, peripheral nerve regeneration and pain	Professor Janet Keast	Anatomy and Neuroscience
The influence of neurotrophin signalling upon the generation of myelin	Dr Simon Murray	Anatomy and Neuroscience
The Role of CXCR7 in Tissue Fibrosis	Dr Asolina Braun	Microbiology and Immunology
The roles of gastrointestinal hormones	Professor John B Furness	Anatomy and Neuroscience
The unique features of visceral pain	Professor Janet Keast	Anatomy and Neuroscience
Transcriptional regulation of intestinal organoid differentiation	Professor Gary Hime	Anatomy and Neuroscience
Uncovering the interplay between innate immunity and the blood brain barrier in disorders of the CNS	Professor Christine Wells	Anatomy and Neuroscience
Understanding the interaction between microbiota and T cell immunity	Associate Professor Sammy Bedoui	Microbiology and Immunology
Understanding the molecular basis of myelin repair	Dr Junhua Xiao	Anatomy and Neuroscience

Cellular Imaging & Structural Biology

Groups / Projects	Research Lead	Dept / Centre
Adverse maternal environment in females born small and transgenerational consequences	Professor Mary Wlodek	Physiology
Analysing and Interpreting protein structures	Dr David Ascher	Biochemistry and Molecular Biology
Being born small programs growth restriction, deficits and disease in the next generation	Professor Mary Wlodek	Physiology
Bo&MeRanG Research Projects	Dr Marie Greyer
Brock laboratory: Autonomic and sensory neuroscience	Associate Professor James Brock	Anatomy and Neuroscience
Can drug-like mimetics of BDNF promote remyelination after injury?	Dr Junhua Xiao	Anatomy and Neuroscience
Cellular Imaging & Structural Biology
Conformational diversity of G-protein coupled receptors and its importance in activation	Associate Professor Paul Gooley	Biochemistry and Molecular Biology
Defining molecular machinery and cargo sorting along Golgi transport pathways	Professor Paul Gleeson	Biochemistry and Molecular Biology
Dendritic cell maturation following different microbial stimulation	Professor William (Bill) Heath	Microbiology and Immunology
Dental morphology	Dr Varsha Pilbrow	Anatomy and Neuroscience
Designing better drugs	Dr David Ascher	Biochemistry and Molecular Biology
Discovery of polyQ ataxin-1 regulation and regulators	Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Early life exercise reprograms pancreatic and heart deficits in offspring born small	Professor Mary Wlodek	Physiology
Factors that accelerate photoreceptor death: The role of purines	Professor Erica Fletcher	Anatomy and Neuroscience
Fletcher laboratory: Visual neuroscience	Professor Erica Fletcher	Anatomy and Neuroscience
Gleeson laboratory: Membrane trafficking and protein sorting in health and disease and development of new therapeutics	Professor Paul Gleeson	Biochemistry and Molecular Biology
Glial cells as a source of progenitor cells in degenerative disease	Professor Erica Fletcher	Anatomy and Neuroscience
Gooley laboratory: Structural biology of disease	Associate Professor Paul Gooley	Biochemistry and Molecular Biology
Gunnersen laboratory: Neuron development and plasticity	Dr Jenny Gunnersen	Anatomy and Neuroscience
Hatters laboratory: Protein misfolding and proteostasis in neurodegenerative diseases	Associate Professor Danny Hatters	Biochemistry and Molecular Biology
Heath laboratory: CD8 T lymphocytes, dendritic cells, self tolerance and immunity	Professor William (Bill) Heath	Microbiology and Immunology
Hinde laboratory: Biophysics of Nuclear Organisation	Dr Elizabeth Hinde	Biochemistry and Molecular Biology
How BDNF signalling controls myelination?	Dr Simon Murray	Anatomy and Neuroscience
How does relaxin activate its G-protein coupled receptor?	Associate Professor Paul Gooley	Biochemistry and Molecular Biology
How sensory signals are detected: Structure function relationships in peripheral sensory nerve terminals	Associate Professor James Brock	Anatomy and Neuroscience
Imaging effector and memory T cell responses in the skin following Herpes Simplex Virus-1 infection	Professor William (Bill) Heath	Microbiology and Immunology
Imaging the priming of CD8 Killer T cell responses to Herpes Simplex Virus-1 skin infection	Professor William (Bill) Heath	Microbiology and Immunology
Imaging transcription factor DNA target search in a living cell	Dr Elizabeth Hinde	Biochemistry and Molecular Biology
Improved vaccines by targeting to dendritic cells	Professor William (Bill) Heath	Microbiology and Immunology
Improving bladder health after spinal cord injury	Associate Professor James Brock	Anatomy and Neuroscience
Intraepithelial T cells in anti-viral immunity	Professor Francis (Frank) Carbone	Microbiology and Immunology
Intravital imaging of T cell responses in the brain during cerebral malaria infection	Professor William (Bill) Heath	Microbiology and Immunology
Keast & Osborne laboratory: Neural development, injury and pain	Professor Janet Keast & Dr Peregrine Osborne	Anatomy and Neuroscience
Keeping JNK in its place	Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Live cell imaging of neural crest cell migration along the developing gut	Professor Heather Young Professor Heather Young	Anatomy and Neuroscience
Lymphoid stromal cell responses to infection	Associate Professor Scott Mueller	Microbiology and Immunology
Malaria and Tissue Resident Memory T cells (TRM) in the liver	Professor William (Bill) Heath	Microbiology and Immunology
Measuring Proteostasis Imbalance in Health and Disease	Associate Professor Danny Hatters	Biochemistry and Molecular Biology Research
Mechanisms of growth factor signalling	Dr Simon Murray	Anatomy and Neuroscience
Mechanisms of Toxicity in Huntington's Disease	Associate Professor Danny Hatters	Biochemistry and Molecular Biology
Migration of melanoma cells in the neural crest environment	Dr Sonja McKeown	Anatomy and Neuroscience
Mueller laboratory: Adaptive immune responses to infection, lymphoid stromal cells, and imaging the immune system	Associate Professor Scott Mueller	Microbiology and Immunology
Murray & Xiao laboratory: Neurotrophin and myelin	Dr Simon Murray & Dr Junhua Xiao	Anatomy and Neuroscience
Nervous regulation of T cell migration and anti-viral Immunity	Associate Professor Scott Mueller	Microbiology and Immunology
Parker Laboratory: Structural biology and computational drug design	Professor Michael Parker	Biochemistry and Molecular Biology
Pilbrow laboratory: Physical (biological) anthropology	Dr Varsha Pilbrow	Anatomy and Neuroscience
Priming of T cell responses to viral infection	Associate Professor Scott Mueller	Microbiology and Immunology
Probing microtubule organisation	Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Protein engineering	Dr David Ascher	Biochemistry and Molecular Biology
Role of chromatin dynamics during the DNA damage response	Dr Elizabeth Hinde	Biochemistry and Molecular Biology
Self-tolerance: Interactions between thymic stroma and dendritic cells	Professor William (Bill) Heath	Microbiology and Immunology
Skeletal morphology	Dr Varsha Pilbrow	Anatomy and Neuroscience
Stojanovski laboratory: Mitochondrial biogenesis in health and disease	Dr Diana Stojanovski	Biochemistry and Molecular Biology
Structural Biology of Cancer	Professor Michael Parker	Biochemistry and Molecular Biology
Structural Biology of Infection	Professor Michael Parker	Biochemistry and Molecular Biology
Structural Neurobiology	Professor Michael Parker	Biochemistry and Molecular Biology
T cell responses in the brain during experimental cerebral malaria infection	Associate Professor Scott Mueller	Microbiology and Immunology
Taylor: Jack Brockhoff Reconstructive Plastic Surgery Research Unit	Professor Ian Taylor	Anatomy and Neuroscience
The influence of neurotrophin signalling upon the generation of myelin	Dr Simon Murray	Anatomy and Neuroscience
The role of glia in inner retinal changes during retinal degeneration	Professor Erica Fletcher	Anatomy and Neuroscience
The role of glial cells in retinal vascular disease	Professor Erica Fletcher	Anatomy and Neuroscience
The role of microglia in age-related macular degeneration	Professor Erica Fletcher	Anatomy and Neuroscience
The role of the rabies P protein in host cell evasion and viral replication	Associate Professor Paul Gooley	Biochemistry and Molecular Biology
Tilley laboratory: Measuring and modelling malaria parasites to develop new antimalarials	Professor Leann Tilley	Biochemistry and Molecular Biology
Tissue-resident memory T cells in the skin	Associate Professor Scott Mueller	Microbiology and Immunology
Understanding neuro-urothelial communication	Professor Janet Keast	Anatomy and Neuroscience
Understanding the molecular basis of myelin repair	Dr Junhua Xiao	Anatomy and Neuroscience
Using biochemical approaches to investigating the trafficking and mechanism of action of the antiviral molecule, IFITM3	Dr Linda Wakim	Microbiology and Immunology
Vaccination against liver-stage Plasmodium for malaria prevention	Professor William (Bill) Heath	Microbiology and Immunology

Infection & Immunity

Groups / Projects	Research Lead	Dept / Centre
A mass spectrometry assay for quantitative analysis of P. falciparum Histidine Rich Protein 2	Professor Gavin E. Reid	Biochemistry and Molecular Biology
A new function of the cytokine BAFF in dendritic cell maturation: Implications for immunity and cancers	Professor Fabienne Mackay \| Dr Beatriz Garcillan	Microbiology and Immunology
A universal vaccine against influenza A	Professor David Jackson	Microbiology and Immunology
Alternative splicing in human parasites	Dr Stuart Ralph	Biochemistry and Molecular Biology
Aminoacyl-tRNA synthetases enzymes as drug targets	Dr Stuart Ralph	Biochemistry and Molecular Biology
Analysing and Interpreting protein structures	Dr David Ascher	Biochemistry and Molecular Biology
Antibody dependent cellular cytotoxicity - a neglected anti-HIV iImmune response!	Professor Stephen Kent, Dr Amy Chung, Dr Matt Parsons	Microbiology and Immunology
Antimicrobial resistant bacterial pathogens	Professor Ben Howden	Microbiology and Immunology
Application of genomics to public health and clinical microbiology	Professor Ben Howden	Microbiology and Immunology
Ascher laboratory: Structural biology and bioinformatics	Dr David Ascher	Biochemistry and Molecular Biology
Australian bite and sting trends: Australian Venomous Injury Project (AVIP)	Dr Ronelle Welton	Pharmacology and Therapeutics
Australian Venom Research Unit	Dr David Williams	Pharmacology and Therapeutics
Autophagy and Norovirus replication	Professor Jason Mackenzie	Microbiology and Immunology
Autophagy: a Novel Pathway of Antigen Presentation in Dendritic Cells	Professor Jose Villadangos	Microbiology and Immunology
Bedoui laboratory: Innate and adaptive interactions in immunity to infection	Associate Professor Sammy Bedoui	Microbiology and Immunology
Biolpolymer-based vaccine delivery systems	Professor David Jackson	Microbiology and Immunology
Bo&MeRanG Research Projects	Dr Marie Greyer
Bogoyevitch laboratory: Regulatory biology	Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Brooks laboratory: Innate immunity; anti-viral immunity	Professor Andrew Brooks	Microbiology and Immunology
Brown laboratory: Immunology; virology; vaccinology	Professor Lorena (Lori) Brown	Microbiology and Immunology
Carbone laboratory: Immune response to herpes simplex virus	Professor Francis (Frank) Carbone	Microbiology and Immunology
Cell biology of membrane receptors regulating the serum half-life of therapeutic proteins	Professor Paul Gleeson	Biochemistry and Molecular Biology
Cell surface receptors for attachment and entry of influenza virus into cells of the innate immune system	Associate Professor Patrick Reading	Microbiology and Immunology
Chronic immune activation during treated HIV disease	Professor Damian Purcell	Microbiology and Immunology
Combined influenza-AIDS vaccines and mucosal vaccinations	Professor Stephen Kent	Microbiology and Immunology
Contribution of proteases to oral cancer pain and metastasis	Dr Laura Edgington-Mitchell	Biochemistry and Molecular Biology
Correlates of severe and fatal influenza disease in high-risk groups	Associate Professor Katherine Kedzierska	Microbiology and Immunology
Coulson laboratory: Rotavirus pathogenesis and immunity	Associate Professor Barbara Coulson	Microbiology and Immunology
Crack laboratory: Neuropharmacology	Associate Professor Peter Crack	Pharmacology and Therapeutics
Deciphering the relative contributions of different dendritic cells to killer T cell responses	Associate Professor Sammy Bedoui	Microbiology and Immunology
Defining molecular machinery and cargo sorting along Golgi transport pathways	Professor Paul Gleeson	Biochemistry and Molecular Biology
Delineating how CD4 T cells ‘help’ establishing effective killer T cell responses	Associate Professor Sammy Bedoui	Microbiology and Immunology
Dendritic cell maturation following different microbial stimulation	Professor William (Bill) Heath	Microbiology and Immunology
Design, development and testing of HIV vaccines	Professor Damian Purcell	Microbiology and Immunology
Designing better drugs	Dr David Ascher	Biochemistry and Molecular Biology
Developing new therapies for Systemic Lupus Erythematosus	Professor Fabienne Mackay	Microbiology and Immunology
Development of a self-adjuvanting vaccine for enterotoxigenic Escherichia coli (ETEC)	Professor David Jackson	Microbiology and Immunology
Development of antimalarial drugs	Professor Leann Tilley	Biochemistry and Molecular Biology
Development of new types of antimicrobial agents	Professor Roy Robins-Browne	Microbiology and Immunology
Development of Novel Chemical Tools to Measure Protease Activation	Dr Laura Edgington-Mitchell	Biochemistry and Molecular Biology
Discovering and characterizing new genes involved in innate immunity, tissue injury and fibrosis	Professor Christine Wells	Anatomy and Neuroscience
Drug target identification in the malaria parasite	Professor Malcolm McConville	Biochemistry and Molecular Biology
Edgington-Mitchell laboratory: Protease Pathophysiology	Dr Laura Edgington-Mitchell	Biochemistry and Molecular Biology
Elucidating the beneficial and harmful elements of the BAFF/APRIL system in multiple sclerosis	Professor Fabienne Mackay \| Dr Beatriz Garcillan	Microbiology and Immunology
Enterococcus faecium	Professor Ben Howden	Microbiology and Immunology
Evolution and spread of drug resistance among bacterial pathogens	A/Prof Kathryn Holt	Biochemistry and Molecular Biology
Function of MARCH ubiquitin ligases	Professor Jose Villadangos	Microbiology and Immunology
Furness laboratory: Digestive physiology and nutrition	Professor John Furness	Anatomy and Neuroscience
Gametocytogenesis - the sexy side of malaria	Professor Leann Tilley	Biochemistry and Molecular Biology
Gebhardt laboratory: Adaptive immune responses to virus infections	Associate Professor Thomas Gebhardt	Microbiology and Immunology
Gene regulation in Plasmodium falciparum	Dr Stuart Ralph	Biochemistry and Molecular Biology
Gleeson laboratory: Membrane trafficking and protein sorting in health and disease and development of new therapeutics	Professor Paul Gleeson	Biochemistry and Molecular Biology
Global health: Typhoid, dysentery and tuberculosis	A/Prof Kathryn Holt	Biochemistry and Molecular Biology
Godfrey laboratory: The development and function of unconventional T cells	Professor Dale Godfrey	Microbiology and Immunology
Going places: Intracellular trafficking for effective immunity	Dr Justine Mintern	Biochemistry and Molecular Biology
Gooley laboratory: Structural biology of disease	Associate Professor Paul Gooley	Biochemistry and Molecular Biology
Gut health in production animals and in human	Professor John B Furness	Anatomy and Neuroscience
Hargreaves laboratory: Exercise physiology	Professor Mark Hargreaves	Physiology
Harnessing dendritic cells for vaccine development	Professor Jose Villadangos	Microbiology and Immunology
Harrap laboratory: Genetic physiology	Professor Stephen Harrap	Physiology
Heat Shock Protein therapy for muscle wasting	Professor Gordon Lynch	Physiology
Heath laboratory: CD8 T lymphocytes, dendritic cells, self tolerance and immunity	Professor William (Bill) Heath	Microbiology and Immunology
Holt laboratory: Pathogen genomics and bioinformatics	A/Prof Kathryn Holt	Biochemistry and Molecular Biology
Hospital bugs – Klebsiella and Acinetobacter	A/Prof Kathryn Holt	Biochemistry and Molecular Biology
How is the immunological T cell memory generated?	Associate Professor Katherine Kedzierska	Microbiology and Immunology
How MR1 molecules present a novel family of antigens to MAIT cells	Dr Hamish McWilliam \| Professor Jose Villadangos	Microbiology and Immunology
Howden laboratory: Molecular epidemiology, genomics and pathogenesis of antimicrobial resistant bacteria	Professor Ben Howden	Microbiology and Immunology
Identification of novel metabolic pathways in Leishmania parasites	Professor Malcolm McConville	Biochemistry and Molecular Biology
Identifying key metabolic pathways required for Toxoplasma gondii infection	Professor Malcolm McConville	Biochemistry and Molecular Biology
Identifying the mechanisms of immune cell development in peripheral tissues	Dr Laura Mackay	Microbiology and Immunology
Imaging effector and memory T cell responses in the skin following Herpes Simplex Virus-1 infection	Professor William (Bill) Heath	Microbiology and Immunology
Imaging the priming of CD8 Killer T cell responses to Herpes Simplex Virus-1 skin infection	Professor William (Bill) Heath	Microbiology and Immunology
Immune responses to pathogenic bacteria		Biochemistry and Molecular Biology
Immuno-paralysis following severe infections or trauma	Professor Jose Villadangos	Microbiology and Immunology
Improved vaccines by targeting to dendritic cells	Professor William (Bill) Heath	Microbiology and Immunology
Improving vaccines: Mechanisms of vaccine biology	Dr Justine Mintern	Biochemistry and Molecular Biology
Infection & Immunity
Influenza A virus PB1-F2 Protein: a putative virulence factor and initiator of inflammation	Dr Julie McAuley	Microbiology and Immunology
Influenza–specific ADCC: Role in a universal flu vaccine?	Professor Stephen Kent	Microbiology and Immunology
Innate T cell recognition and development	Dr Daniel Pellicci	Microbiology and Immunology
Innovative approaches to prepare synthetic, partially synthetic and natural product-based vaccines	Professor David Jackson	Microbiology and Immunology
Intraepithelial T cells in anti-viral immunity	Professor Francis (Frank) Carbone	Microbiology and Immunology
Intravital imaging of T cell responses in the brain during cerebral malaria infection	Professor William (Bill) Heath	Microbiology and Immunology
Investigation of HSV latency and reactivation	Professor Francis (Frank) Carbone	Microbiology and Immunology
Jackson laboratory: Synthetic vaccine design	Professor David Jackson	Microbiology and Immunology
Joining the immunotherapy revolution: Adoptive cell therapy against cancer	Professor Jose Villadangos	Microbiology and Immunology
Kedzierska laboratory: Immunity to pandemic and newly emerged influenza viruses	Associate Professor Katherine Kedzierska	Microbiology and Immunology
Kent laboratory: HIV vaccines; immune responses to HIV-1; immunotherapy	Professor Stephen Kent	Microbiology and Immunology
Klebsiella pneumoniae	Professor Dick Strugnell	Microbiology and Immunology
Koopman laboratory: Clinical nutrition and muscle metabolism	Dr René Koopman	Physiology
Lawson laboratory: Neurodegenerative disease caused by prions	Associate Professor Vicki Lawson	Microbiology and Immunology
Lew laboratory: Theoretical and empirical pharmacology	Dr Michael Lew	Pharmacology and Therapeutics
Lipidome profiling of inflammatory biomarkers for beta cell autoimmunity in type 1 diabetes	Professor Gavin E. Reid	Biochemistry and Molecular Biology
Lipopeptide-based adjuvanting systems	Professor David Jackson	Microbiology and Immunology
Lung Disease Research Laboratory	Professor Gary P Anderson	Pharmacology and Therapeutics
Lung Health Research Centre		Pharmacology and Therapeutics
Lymphoid stromal cell responses to infection	Associate Professor Scott Mueller	Microbiology and Immunology
Mackay (F) laboratory: B lymphocytes, BAFF, autoimmunity and cancer	Professor Fabienne Mackay	Microbiology and Immunology
Mackay (L) laboratory: Tissue-resident memory T cells; lymphocyte differentiation; peripheral immunity	Dr Laura Mackay	Microbiology and Immunology
Mackenzie laboratory: Intracellular virus replication and innate immunity	Professor Jason Mackenzie	Microbiology and Immunology
Malaria and Tissue Resident Memory T cells (TRM) in the liver	Professor William (Bill) Heath	Microbiology and Immunology
McCluskey laboratory: Role of MAIT cells in health and disease	Professor James McCluskey	Microbiology and Immunology
McConville laboratory: Molecular microbiology	Professor Malcolm McConville	Biochemistry and Molecular Biology
Mechanisms underlying early generation of human T cell memory	Associate Professor Katherine Kedzierska	Microbiology and Immunology
Memory T cell responses in the lung during virus infection	Dr Linda Wakim	Microbiology and Immunology
Mintern laboratory: Vaccine biology	Dr Justine Mintern	Biochemistry and Molecular Biology
Molecular immunology and autoimmunity	Professor Paul Gleeson	Biochemistry and Molecular Biology
Mueller laboratory: Adaptive immune responses to infection, lymphoid stromal cells, and imaging the immune system	Associate Professor Scott Mueller	Microbiology and Immunology
Munsie laboratory: Ethical, legal and social implications of stem cell research	Associate Professor Megan Munsie	Anatomy and Neuroscience
Mycobacterium ulcerans	Professor TIm Stinear	Microbiology and Immunology
Nanoparticle HIV vaccines	Professor Stephen Kent	Microbiology and Immunology
Nanoparticle Modulation of Mast Cell Function	Dr Graham Mackay	Pharmacology and Therapeutics
Nervous regulation of T cell migration and anti-viral Immunity	Associate Professor Scott Mueller	Microbiology and Immunology
Newton laboratory: Virulence strategies of intracellular bacterial pathogens	Dr Hayley Newton	Microbiology and Immunology
NK cell receptor biology	Professor Andrew Brooks	Microbiology and Immunology
NKT cells, MAIT cells, CD1-restricted T cells and HIV	Professor Stephen Kent	Microbiology and Immunology
Non-classical MHC and Class 1-like molecules	Professor Andrew Brooks	Microbiology and Immunology
Norovirus replication and innate immunity	Professor Jason Mackenzie	Microbiology and Immunology
Novel Mast Cell-Derived Mediators	Dr Graham Mackay	Pharmacology and Therapeutics
Parker Laboratory: Structural biology and computational drug design	Professor Michael Parker	Biochemistry and Molecular Biology
Passive antibody immunity for use in combination microbicides	Professor Damian Purcell	Microbiology and Immunology
Pathogenesis of chronic lung disease	Dr Michelle Hansen	Pharmacology and Therapeutics
Pathogenic bacteria that target mitochondria	Dr Diana Stojanovski	Biochemistry and Molecular Biology
Priming of T cell responses to viral infection	Associate Professor Scott Mueller	Microbiology and Immunology
Protein engineering	Dr David Ascher	Biochemistry and Molecular Biology
Purcell laboratory: Viral RNA elements, regulation of HIV replication, HIV antibody vaccine	Professor Damian Purcell	Microbiology and Immunology
Ralph laboratory: Drug targets and gene regulation in Plasmodium falciparum	Dr Stuart Ralph	Biochemistry and Molecular Biology
Reading laboratory: Innate immune detection and response to respiratory virus infections	Associate Professor Patrick Reading	Microbiology and Immunology
Regulation of Mast Cell Activation	Dr Graham Mackay	Pharmacology and Therapeutics
Regulation of telomerase activity in B cells	Dr Asolina Braun	Microbiology and Immunology
Respiratory microbiome in infants and children	A/Prof Kathryn Holt	Biochemistry and Molecular Biology
Restoring immunocompetency in Chronic Lymphocytic Leukemia	Professor Fabienne Mackay	Microbiology and Immunology
RNA mediated control of HIV-1 gene expression	Professor Damian Purcell	Microbiology and Immunology
Robins-Browne laboratory: Medical bacteriology, pathogenesis, bacterial genetics, therapeutics	Professor Roy Robins-Browne	Microbiology and Immunology
Role of cellular lipids during Flavivirus replication	Professor Jason Mackenzie	Microbiology and Immunology
Role of innate signals in inducing protective T cell immunity	Associate Professor Sammy Bedoui	Microbiology and Immunology
Role of interferon inducible GTPases in immune defence		Biochemistry and Molecular Biology
Rotavirus induction and evasion of innate immunity	Associate Professor Barbara Coulson	Microbiology and Immunology
Rotavirus modulation of type 1 diabetes development	Associate Professor Barbara Coulson	Microbiology and Immunology
Rotavirus-cell binding and entry	Associate Professor Barbara Coulson	Microbiology and Immunology
Salmonella Typhimurium	Professor Dick Strugnell	Microbiology and Immunology
Self-tolerance: Interactions between thymic stroma and dendritic cells	Professor William (Bill) Heath	Microbiology and Immunology
Simmons laboratory: Dengue; pathogenesis, epidemiology, therapeutics, entomology	Professor Cam Simmons	Microbiology and Immunology
Soluble barriers to influenza virus infection	Associate Professor Patrick Reading	Microbiology and Immunology
Staphylococcus aureus & Enterococcus faecium	Professor Tim Stinear	Microbiology and Immunology
Staphylococcus aureus and Staphylococcus epidermidis	Professor Ben Howden	Microbiology and Immunology
Stinear laboratory: Bacterial pathogenomics	Professor Tim Stinear	Microbiology and Immunology
Strugnell laboratory: Bacterial pathogenesis and host responses	Professor Dick Strugnell	Microbiology and Immunology
T cell responses in the brain during experimental cerebral malaria infection	Associate Professor Scott Mueller	Microbiology and Immunology
T cells in peripheral immunity	Professor Francis (Frank) Carbone	Microbiology and Immunology
Tackling drug resistance	Dr David Ascher	Biochemistry and Molecular Biology
The Cardiovascular Pharmacology of Snake Venoms From Papua New Guinea and Australia	Associate Professor Christine Wright	Pharmacology and Therapeutics
The innate immune system in the respiratory tract	Professor David Jackson	Microbiology and Immunology
The mechanisms of viral escape in murine and human influenza infection	Associate Professor Katherine Kedzierska	Microbiology and Immunology
The role of CD4+ T cells in viral infections	Professor Andrew Brooks	Microbiology and Immunology
The Role of CXCR7 in Tissue Fibrosis	Dr Asolina Braun	Microbiology and Immunology
The role of glucose metabolism and O-GlcNAc glycosylation in the regulation of immunity	Dr Nishma Gupta \| Professor Jose Villadangos	Microbiology and Immunology
The role of innate immune cells in protection and pathology during influenza virus infection	Associate Professor Patrick Reading	Microbiology and Immunology
The role of resident memory T cells in barrier immunity and autoimmune disease	Dr Laura Mackay	Microbiology and Immunology
The role of the rabies P protein in host cell evasion and viral replication	Associate Professor Paul Gooley	Biochemistry and Molecular Biology
The roles of gastrointestinal hormones	Professor John B Furness	Anatomy and Neuroscience
The Treatment of Papuan Taipan Envenoming in Papua New Guinea	Dr David Williams	Pharmacology and Therapeutics
Tilley laboratory: Measuring and modelling malaria parasites to develop new antimalarials	Professor Leann Tilley	Biochemistry and Molecular Biology
Tissue-resident memory T cells in the skin	Associate Professor Scott Mueller	Microbiology and Immunology
Tracking phenotypically and functionally distinct T cell subsets via T cell repertoire diversity	Associate Professor Katherine Kedzierska	Microbiology and Immunology
Uncovering the interplay between innate immunity and the blood brain barrier in disorders of the CNS	Professor Christine Wells	Anatomy and Neuroscience
Understanding the interaction between microbiota and T cell immunity	Associate Professor Sammy Bedoui	Microbiology and Immunology
Understanding the molecular consequences of mutations	Dr David Ascher	Biochemistry and Molecular Biology
Understanding the regulation of tissue-resident memory T cell development	Dr Laura Mackay	Microbiology and Immunology
Understanding the role of glycine in the control of skeletal muscle mass during sepsis	Dr René Koopman	Physiology
Understanding ‘universal’ influenza-specific CD8+ T cell responses	Associate Professor Katherine Kedzierska	Microbiology and Immunology
Using biochemical approaches to investigating the trafficking and mechanism of action of the antiviral molecule, IFITM3	Dr Linda Wakim	Microbiology and Immunology
Vaccination against liver-stage Plasmodium for malaria prevention	Professor William (Bill) Heath	Microbiology and Immunology
Vagal nerve stimulation for the treatment of inflammatory bowel disease	Professor John B Furness	Anatomy and Neuroscience
van Driel laboratory: Immune responses to pathogens	Professor Ian van Driel	Biochemistry and Molecular Biology
Velkov laboratory: Antiinfective pharmacology	Associate Professor Tony Velkov	Pharmacology and Therapeutics
Villadangos laboratory: Antigen presenting cells & molecules that initiate T cell immunity against pathogens and cancer	Professor Jose Villadangos	Microbiology and Immunology
Viral interactions with the innate immune system	Associate Professor Patrick Reading	Microbiology and Immunology
Visualization and formation West Nile Virus replication complexes	Professor Jason Mackenzie	Microbiology and Immunology
Wakim laboratory: Antiviral molecules, mucosal immunology, influenza virus, tissue resident memory T cells	Dr Linda Wakim	Microbiology and Immunology
Wells laboratory: Stem cell systems	Professor Christine Wells	Anatomy and Neuroscience
West Nile Virus replication and cellular stress responses	Professor Jason Mackenzie	Microbiology and Immunology
Wolbachia to stop dengue transmission in Vietnam and Indonesia	Professor Cameron Simmons	Microbiology and Immunology

Molecular Mechanisms of Disease

Groups / Projects	Research Lead	Dept / Centre
A mass spectrometry assay for quantitative analysis of P. falciparum Histidine Rich Protein 2	Professor Gavin E. Reid	Biochemistry and Molecular Biology
A universal vaccine against influenza A	Professor David Jackson	Microbiology and Immunology
Alternative splicing in human parasites	Dr Stuart Ralph	Biochemistry and Molecular Biology
Analysing and Interpreting protein structures	Dr David Ascher	Biochemistry and Molecular Biology
Angiotensin and chemoreceptor function	Professor Andrew Allen	Physiology
Antibody dependent cellular cytotoxicity - a neglected anti-HIV iImmune response!	Professor Stephen Kent, Dr Amy Chung, Dr Matt Parsons	Microbiology and Immunology
Antimicrobial resistant bacterial pathogens	Professor Ben Howden	Microbiology and Immunology
Apolipoproteins and amyloid fibril formation in disease	Dr Michael Griffin	Biochemistry and Molecular Biology
Application of genomics to public health and clinical microbiology	Professor Ben Howden	Microbiology and Immunology
Ascher laboratory: Structural biology and bioinformatics	Dr David Ascher	Biochemistry and Molecular Biology
Autophagy and Norovirus replication	Professor Jason Mackenzie	Microbiology and Immunology
Barrett laboratory: Neural plasticity and neurotrophins	Associate Professor Graham Barrett	Physiology
Bedoui laboratory: Innate and adaptive interactions in immunity to infection	Associate Professor Sammy Bedoui	Microbiology and Immunology
Biochemical and structural basis of the tumour suppression mechanism of CSK-homologous kinase	Associate Professor Heung-Chin Cheng	Biochemistry and Molecular Biology
Biolpolymer-based vaccine delivery systems	Professor David Jackson	Microbiology and Immunology
Bo&MeRanG Research Projects	Dr Marie Greyer
Bogoyevitch laboratory: Regulatory biology	Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Bornstein laboratory: Enteric neuroscience	Professor Joel C Bornstein	Physiology
Brain networks processing respiratory sensations	Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Brooks laboratory: Innate immunity; anti-viral immunity	Professor Andrew Brooks	Microbiology and Immunology
Brown laboratory: Immunology; virology; vaccinology	Professor Lorena (Lori) Brown	Microbiology and Immunology
Calbindins - what do they do?	Professor Mike Hubbard	Pharmacology and Therapeutics
Can drug-like mimetics of BDNF promote remyelination after injury?	Dr Junhua Xiao	Anatomy and Neuroscience
Cappai laboratory: Alzheimer's disease, prion disease, Parkinson's disease and Traumatic Brain Injury	Professor Roberto Cappai	Pharmacology and Therapeutics
Carbone laboratory: Immune response to herpes simplex virus	Professor Francis (Frank) Carbone	Microbiology and Immunology
Cell surface receptors for attachment and entry of influenza virus into cells of the innate immune system	Associate Professor Patrick Reading	Microbiology and Immunology
Chalky teeth - can they be prevented?	Professor Mike Hubbard	Pharmacology and Therapeutics
Cheng laboratory: Molecular enzymology of protein kinases and phosphatases involved in human diseases	Associate Professor Heung-Chin Cheng	Biochemistry and Molecular Biology
Chronic immune activation during treated HIV disease	Professor Damian Purcell	Microbiology and Immunology
Combined influenza-AIDS vaccines and mucosal vaccinations	Professor Stephen Kent	Microbiology and Immunology
Comprehensive lipidome profiling to identify functional biomarkers of colorectal cancer metastasis	Professor Gavin E. Reid	Biochemistry and Molecular Biology
Contribution of proteases to oral cancer pain and metastasis	Dr Laura Edgington-Mitchell	Biochemistry and Molecular Biology
Correlates of severe and fatal influenza disease in high-risk groups	Associate Professor Katherine Kedzierska	Microbiology and Immunology
Coulson laboratory: Rotavirus pathogenesis and immunity	Associate Professor Barbara Coulson	Microbiology and Immunology
Crack laboratory: Neuropharmacology	Associate Professor Peter Crack	Pharmacology and Therapeutics
Crouch laboratory: Neurodegenerative disease	Dr Peter Crouch	Pharmacology and Therapeutics
De Iongh laboratory: Ocular development laboratory	Associate Professor Robb de Iongh	Anatomy and Neuroscience
Deciphering the relative contributions of different dendritic cells to killer T cell responses	Associate Professor Sammy Bedoui	Microbiology and Immunology
Delbridge laboratory: Cardiac phenomics	Professor Lea Delbridge	Physiology
Delineating how CD4 T cells ‘help’ establishing effective killer T cell responses	Associate Professor Sammy Bedoui	Microbiology and Immunology
Dendritic cell maturation following different microbial stimulation	Professor William (Bill) Heath	Microbiology and Immunology
Design, development and testing of HIV vaccines	Professor Damian Purcell	Microbiology and Immunology
Developing new therapies for Systemic Lupus Erythematosus	Professor Fabienne Mackay	Microbiology and Immunology
Development of a self-adjuvanting vaccine for enterotoxigenic Escherichia coli (ETEC)	Professor David Jackson	Microbiology and Immunology
Development of autonomic and nociceptive circuits	Professor Janet Keast	Anatomy and Neuroscience
Development of new types of antimicrobial agents	Professor Roy Robins-Browne	Microbiology and Immunology
Development of Novel Chemical Tools to Measure Protease Activation	Dr Laura Edgington-Mitchell	Biochemistry and Molecular Biology
Diabetic cardiomyopathy – an epidemic disease	Professor Lea Delbridge	Physiology
Discovering and characterizing new genes involved in innate immunity, tissue injury and fibrosis	Professor Christine Wells	Anatomy and Neuroscience
Discovery of polyQ ataxin-1 regulation and regulators	Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Drug target identification in the malaria parasite	Professor Malcolm McConville	Biochemistry and Molecular Biology
Edgington-Mitchell laboratory: Protease Pathophysiology	Dr Laura Edgington-Mitchell	Biochemistry and Molecular Biology
Enamel cell biology – how is bulk calcium handled safely?	Professor Mike Hubbard	Pharmacology and Therapeutics
Enterococcus faecium	Professor Ben Howden	Microbiology and Immunology
ERp29 – what does it do?	Professor Mike Hubbard	Pharmacology and Therapeutics
Factors that accelerate photoreceptor death: The role of purines	Professor Erica Fletcher	Anatomy and Neuroscience
Fletcher laboratory: Visual neuroscience	Professor Erica Fletcher	Anatomy and Neuroscience
Furness laboratory: Digestive physiology and nutrition	Professor John Furness	Anatomy and Neuroscience
Gametocytogenesis - the sexy side of malaria	Professor Leann Tilley	Biochemistry and Molecular Biology
Gebhardt laboratory: Adaptive immune responses to virus infections	Associate Professor Thomas Gebhardt	Microbiology and Immunology
Gene regulation in Plasmodium falciparum	Dr Stuart Ralph	Biochemistry and Molecular Biology
Gleeson laboratory: Membrane trafficking and protein sorting in health and disease and development of new therapeutics	Professor Paul Gleeson	Biochemistry and Molecular Biology
Glial cells as a source of progenitor cells in degenerative disease	Professor Erica Fletcher	Anatomy and Neuroscience
Godfrey laboratory: The development and function of unconventional T cells	Professor Dale Godfrey	Microbiology and Immunology
Going places: Intracellular trafficking for effective immunity	Dr Justine Mintern	Biochemistry and Molecular Biology
Gooley laboratory: Structural biology of disease	Associate Professor Paul Gooley	Biochemistry and Molecular Biology
Griffin laboratory: Functional and mis-functional protein-protein interactions	Dr Michael Griffin	Biochemistry and Molecular Biology
Gunnersen laboratory: Neuron development and plasticity	Dr Jenny Gunnersen	Anatomy and Neuroscience
Gut health in production animals and in human	Professor John B Furness	Anatomy and Neuroscience
Hargreaves laboratory: Exercise physiology	Professor Mark Hargreaves	Physiology
Hatters laboratory: Protein misfolding and proteostasis in neurodegenerative diseases	Associate Professor Danny Hatters	Biochemistry and Molecular Biology
Heat Shock Protein therapy for muscle wasting	Professor Gordon Lynch	Physiology
Heath laboratory: CD8 T lymphocytes, dendritic cells, self tolerance and immunity	Professor William (Bill) Heath	Microbiology and Immunology
Hinde laboratory: Biophysics of Nuclear Organisation	Dr Elizabeth Hinde	Biochemistry and Molecular Biology
How BDNF signalling controls myelination?	Dr Simon Murray	Anatomy and Neuroscience
How does GM-CSF prevent brain damage after traumatic injury?	Dr Jenny Gunnersen Dr Sandy Shultz	Anatomy and Neuroscience
How is the immunological T cell memory generated?	Associate Professor Katherine Kedzierska	Microbiology and Immunology
Howden laboratory: Molecular epidemiology, genomics and pathogenesis of antimicrobial resistant bacteria	Professor Ben Howden	Microbiology and Immunology
Hoyer laboratory: Translational neuroscience	Professor Daniel Hoyer	Pharmacology and Therapeutics
Human brain networks processing respiratory sensations	Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Hypothalamic modulation of basal sympathetic activity	Professor Andrew Allen	Physiology
Identification of novel metabolic pathways in Leishmania parasites	Professor Malcolm McConville	Biochemistry and Molecular Biology
Identifying key metabolic pathways required for Toxoplasma gondii infection	Professor Malcolm McConville	Biochemistry and Molecular Biology
Identifying the mechanisms of immune cell development in peripheral tissues	Dr Laura Mackay	Microbiology and Immunology
Imaging effector and memory T cell responses in the skin following Herpes Simplex Virus-1 infection	Professor William (Bill) Heath	Microbiology and Immunology
Imaging the priming of CD8 Killer T cell responses to Herpes Simplex Virus-1 skin infection	Professor William (Bill) Heath	Microbiology and Immunology
Imaging transcription factor DNA target search in a living cell	Dr Elizabeth Hinde	Biochemistry and Molecular Biology
Immune responses to pathogenic bacteria		Biochemistry and Molecular Biology
Improved vaccines by targeting to dendritic cells	Professor William (Bill) Heath	Microbiology and Immunology
Improving recovery of injured visceral nerves and their spinal control centres	Professor Janet Keast	Anatomy and Neuroscience
Improving the diagnostic outcomes of patients with mitochondrial disease	Dr David Stroud	Biochemistry and Molecular Biology
Improving vaccines: Mechanisms of vaccine biology	Dr Justine Mintern	Biochemistry and Molecular Biology
Influenza A virus PB1-F2 Protein: a putative virulence factor and initiator of inflammation	Dr Julie McAuley	Microbiology and Immunology
Influenza–specific ADCC: Role in a universal flu vaccine?	Professor Stephen Kent	Microbiology and Immunology
Innate immunity and neural injury	Associate Professor Peter Crack	Pharmacology and Therapeutics
Innate T cell recognition and development	Dr Daniel Pellicci	Microbiology and Immunology
Innovative approaches to prepare synthetic, partially synthetic and natural product-based vaccines	Professor David Jackson	Microbiology and Immunology
Interplay of sex differentiation and metabolism	Associate Professor Dagmar Wilhelm	Anatomy and Neuroscience
Intraepithelial T cells in anti-viral immunity	Professor Francis (Frank) Carbone	Microbiology and Immunology
Intravital imaging of T cell responses in the brain during cerebral malaria infection	Professor William (Bill) Heath	Microbiology and Immunology
Investigation of HSV latency and reactivation	Professor Francis (Frank) Carbone	Microbiology and Immunology
Is the “shed” form of Sez-6 proteins responsible for their synapse-promoting effects?	Dr Jenny Gunnersen Dr Kathryn Munro	Anatomy and Neuroscience
Ivanusic laboratory: Pain and sensory mechanisms	Dr Jason Ivanusic	Anatomy and Neuroscience
Jackson laboratory: Synthetic vaccine design	Professor David Jackson	Microbiology and Immunology
Keast & Osborne laboratory: Neural development, injury and pain	Professor Janet Keast & Dr Peregrine Osborne	Anatomy and Neuroscience
Kedzierska laboratory: Immunity to pandemic and newly emerged influenza viruses	Associate Professor Katherine Kedzierska	Microbiology and Immunology
Kent laboratory: HIV vaccines; immune responses to HIV-1; immunotherapy	Professor Stephen Kent	Microbiology and Immunology
Kilpatrick laboratory: Neuroimmunology of Multiple Sclerosis	Professor Trevor Kilpatrick	Anatomy and Neuroscience
Klebsiella pneumoniae	Professor Dick Strugnell	Microbiology and Immunology
Koopman laboratory: Clinical nutrition and muscle metabolism	Dr René Koopman	Physiology
Lawson laboratory: Neurodegenerative disease caused by prions	Associate Professor Vicki Lawson	Microbiology and Immunology
Lipidome profiling of inflammatory biomarkers for beta cell autoimmunity in type 1 diabetes	Professor Gavin E. Reid	Biochemistry and Molecular Biology
Lipopeptide-based adjuvanting systems	Professor David Jackson	Microbiology and Immunology
Lung Disease Research Laboratory	Professor Gary P Anderson	Pharmacology and Therapeutics
Lynch laboratory: Basic and clinical myology	Professor Gordon Lynch	Physiology
Mackay (F) laboratory: B lymphocytes, BAFF, autoimmunity and cancer	Professor Fabienne Mackay	Microbiology and Immunology
Mackay (L) laboratory: Tissue-resident memory T cells; lymphocyte differentiation; peripheral immunity	Dr Laura Mackay	Microbiology and Immunology
Mackenzie laboratory: Intracellular virus replication and innate immunity	Professor Jason Mackenzie	Microbiology and Immunology
Malaria and Tissue Resident Memory T cells (TRM) in the liver	Professor William (Bill) Heath	Microbiology and Immunology
Mangum laboratory: Proteomics and calcium biology	Dr Jon Mangum	Pharmacology and Therapeutics
Mapping the distribution of angiotensin receptors in the brain	Professor Andrew Allen	Physiology
Mature and developing synaptic transmission between defined classes of enteric neurons	Dr Jaime Foong	Physiology
Mazzone laboratory: Respiratory Sensory Neuroscience	Associate Professor Stuart Mazzone	Anatomy and Neuroscience Research
McCluskey laboratory: Role of MAIT cells in health and disease	Professor James McCluskey	Microbiology and Immunology
McConville laboratory: Molecular microbiology	Professor Malcolm McConville	Biochemistry and Molecular Biology
Mechanisms of growth factor signalling	Dr Simon Murray	Anatomy and Neuroscience
Mechanisms underlying early generation of human T cell memory	Associate Professor Katherine Kedzierska	Microbiology and Immunology
Memory T cell responses in the lung during virus infection	Dr Linda Wakim	Microbiology and Immunology
Mintern laboratory: Vaccine biology	Dr Justine Mintern	Biochemistry and Molecular Biology
Mitochondrial protein biogenesis in mammalian cells	Dr Diana Stojanovski	Biochemistry and Molecular Biology
Modelling sensory neuron-epithelial interactions	Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Molecular and cellular analysis of mammalian ovary development and disease	Associate Professor Dagmar Wilhelm	Anatomy and Neuroscience
Molecular immunology and autoimmunity	Professor Paul Gleeson	Biochemistry and Molecular Biology
Molecular Mechanisms of Disease
Molecular mechanisms that contribute to bone marrow pain	Dr Jason Ivanusic	Anatomy and Neuroscience
Mueller laboratory: Adaptive immune responses to infection, lymphoid stromal cells, and imaging the immune system	Associate Professor Scott Mueller	Microbiology and Immunology
Murray & Xiao laboratory: Neurotrophin and myelin	Dr Simon Murray & Dr Junhua Xiao	Anatomy and Neuroscience
Mycobacterium ulcerans	Professor TIm Stinear	Microbiology and Immunology
Nanoparticle HIV vaccines	Professor Stephen Kent	Microbiology and Immunology
Nanoparticle Modulation of Mast Cell Function	Dr Graham Mackay	Pharmacology and Therapeutics
Newton laboratory: Virulence strategies of intracellular bacterial pathogens	Dr Hayley Newton	Microbiology and Immunology
NK cell receptor biology	Professor Andrew Brooks	Microbiology and Immunology
NKT cells, MAIT cells, CD1-restricted T cells and HIV	Professor Stephen Kent	Microbiology and Immunology
Non-classical MHC and Class 1-like molecules	Professor Andrew Brooks	Microbiology and Immunology
Norovirus replication and innate immunity	Professor Jason Mackenzie	Microbiology and Immunology
Novel Mast Cell-Derived Mediators	Dr Graham Mackay	Pharmacology and Therapeutics
Oxidative stress and neural injury	Associate Professor Peter Crack	Pharmacology and Therapeutics
Pain management using ultrasound-guided local anaesthetic techniques	Dr Jason Ivanusic	Anatomy and Neuroscience Research
Parker Laboratory: Structural biology and computational drug design	Professor Michael Parker	Biochemistry and Molecular Biology
Passive antibody immunity for use in combination microbicides	Professor Damian Purcell	Microbiology and Immunology
Pathogenic bacteria that target mitochondria	Dr Diana Stojanovski	Biochemistry and Molecular Biology
Personalising treatments for genetic diseases	Dr David Ascher	Biochemistry and Molecular Biology
Post-translational control of cell fate decisions	Associate Professor Dagmar Wilhelm	Anatomy and Neuroscience
Potential of cell therapy to treat Hirschsprung’s disease	Professor Heather Young Dr Lincon Stamp	Anatomy and Neuroscience
Probing microtubule organisation	Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Proliferation of enteric neuron precursors	Professor Heather Young Professor Heather Young	Anatomy and Neuroscience
Protein kinases involved in pathogenesis of Parkinson’s disease	Associate Professor Heung-Chin Cheng	Biochemistry and Molecular Biology
Purcell laboratory: Viral RNA elements, regulation of HIV replication, HIV antibody vaccine	Professor Damian Purcell	Microbiology and Immunology
Ralph laboratory: Drug targets and gene regulation in Plasmodium falciparum	Dr Stuart Ralph	Biochemistry and Molecular Biology
Reading laboratory: Innate immune detection and response to respiratory virus infections	Associate Professor Patrick Reading	Microbiology and Immunology
Regulation of Mast Cell Activation	Dr Graham Mackay	Pharmacology and Therapeutics
Reid laboratory: Proteomics and lipidomics in health and disease	Professor Gavin E. Reid	Biochemistry and Molecular Biology
Restoring immunocompetency in Chronic Lymphocytic Leukemia	Professor Fabienne Mackay	Microbiology and Immunology
RNA mediated control of HIV-1 gene expression	Professor Damian Purcell	Microbiology and Immunology
Robins-Browne laboratory: Medical bacteriology, pathogenesis, bacterial genetics, therapeutics	Professor Roy Robins-Browne	Microbiology and Immunology
Role of cellular lipids during Flavivirus replication	Professor Jason Mackenzie	Microbiology and Immunology
Role of chromatin dynamics during the DNA damage response	Dr Elizabeth Hinde	Biochemistry and Molecular Biology
Role of innate signals in inducing protective T cell immunity	Associate Professor Sammy Bedoui	Microbiology and Immunology
Role of interferon inducible GTPases in immune defence		Biochemistry and Molecular Biology
Rotavirus induction and evasion of innate immunity	Associate Professor Barbara Coulson	Microbiology and Immunology
Rotavirus modulation of type 1 diabetes development	Associate Professor Barbara Coulson	Microbiology and Immunology
Rotavirus-cell binding and entry	Associate Professor Barbara Coulson	Microbiology and Immunology
Salmonella Typhimurium	Professor Dick Strugnell	Microbiology and Immunology
Saunders laboratory: Developmental neuroscience and neurotrauma	Professor Norman Saunders	Pharmacology and Therapeutics
Self-tolerance: Interactions between thymic stroma and dendritic cells	Professor William (Bill) Heath	Microbiology and Immunology
Signals for endosomal sorting in development and disease	Professor Paul Gleeson	Biochemistry and Molecular Biology
Simmons laboratory: Dengue; pathogenesis, epidemiology, therapeutics, entomology	Professor Cam Simmons	Microbiology and Immunology
Soluble barriers to influenza virus infection	Associate Professor Patrick Reading	Microbiology and Immunology
Staphylococcus aureus & Enterococcus faecium	Professor Tim Stinear	Microbiology and Immunology
Staphylococcus aureus and Staphylococcus epidermidis	Professor Ben Howden	Microbiology and Immunology
Steroid hormones and heart failure – sex perspectives	Professor Lea Delbridge	Physiology
Stojanovski laboratory: Mitochondrial biogenesis in health and disease	Dr Diana Stojanovski	Biochemistry and Molecular Biology
Stroke	Associate Professor Peter Crack	Pharmacology and Therapeutics
Stroud laboratory: Mitochondrial Systems Biology	Dr David Stroud	Biochemistry and Molecular Biology
Structural Biology of Cancer	Professor Michael Parker	Biochemistry and Molecular Biology
Structural Biology of Infection	Professor Michael Parker	Biochemistry and Molecular Biology
Structural Neurobiology	Professor Michael Parker	Biochemistry and Molecular Biology
Strugnell laboratory: Bacterial pathogenesis and host responses	Professor Dick Strugnell	Microbiology and Immunology
T cells in peripheral immunity	Professor Francis (Frank) Carbone	Microbiology and Immunology
Tackling drug resistance	Dr David Ascher	Biochemistry and Molecular Biology
The Enteric Neural Circuitry Activated During Bacterial-toxin Induced Diarrhoea	Dr Jaime Foong	Physiology
The GDNF family, peripheral nerve regeneration and pain	Professor Janet Keast	Anatomy and Neuroscience
The influence of neurotrophin signalling upon the generation of myelin	Dr Simon Murray	Anatomy and Neuroscience
The innate immune system in the respiratory tract	Professor David Jackson	Microbiology and Immunology
The mechanisms of viral escape in murine and human influenza infection	Associate Professor Katherine Kedzierska	Microbiology and Immunology
The role of CD4+ T cells in viral infections	Professor Andrew Brooks	Microbiology and Immunology
The Role of CXCR7 in Tissue Fibrosis	Dr Asolina Braun	Microbiology and Immunology
The Role of enteric neurons in gastrointestinal symptoms associated with Autism Spectrum disorders	Dr Elisa Hill-Yardin	Physiology
The role of glia in inner retinal changes during retinal degeneration	Professor Erica Fletcher	Anatomy and Neuroscience
The role of glial cells in retinal vascular disease	Professor Erica Fletcher	Anatomy and Neuroscience
The role of innate immune cells in protection and pathology during influenza virus infection	Associate Professor Patrick Reading	Microbiology and Immunology
The role of microglia in age-related macular degeneration	Professor Erica Fletcher	Anatomy and Neuroscience
The role of non-coding RNA in embryonic development	Associate Professor Dagmar Wilhelm	Anatomy and Neuroscience
The role of resident memory T cells in barrier immunity and autoimmune disease	Dr Laura Mackay	Microbiology and Immunology
The structure of the IL-11 signalling complex	Dr Michael Griffin	Biochemistry and Molecular Biology
The unique features of visceral pain	Professor Janet Keast	Anatomy and Neuroscience
Therapeutic potential of skeletal muscle plasticity and slow muscle programming for muscular dystrophy	Professor Gordon Lynch	Physiology
Tracking phenotypically and functionally distinct T cell subsets via T cell repertoire diversity	Associate Professor Katherine Kedzierska	Microbiology and Immunology
Transcriptional profiling of sensory neurons	Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Traumatic brain injury	Associate Professor Peter Crack	Pharmacology and Therapeutics
Uncovering the interplay between innate immunity and the blood brain barrier in disorders of the CNS	Professor Christine Wells	Anatomy and Neuroscience
Understanding neuro-urothelial communication	Professor Janet Keast	Anatomy and Neuroscience
Understanding the aetiology of hypertension	Professor Andrew Allen	Physiology
Understanding the assembly of mitochondrial machines	Dr David Stroud	Biochemistry and Molecular Biology
Understanding the interaction between microbiota and T cell immunity	Associate Professor Sammy Bedoui	Microbiology and Immunology
Understanding the molecular basis of myelin repair	Dr Junhua Xiao	Anatomy and Neuroscience
Understanding the molecular consequences of mutations	Dr David Ascher	Biochemistry and Molecular Biology
Understanding the regulation of tissue-resident memory T cell development	Dr Laura Mackay	Microbiology and Immunology
Understanding the role of angiotensin in the rostral ventrolateral medulla	Professor Andrew Allen	Physiology
Understanding the role of glycine in the control of skeletal muscle mass during sepsis	Dr René Koopman	Physiology
Understanding ‘universal’ influenza-specific CD8+ T cell responses	Associate Professor Katherine Kedzierska	Microbiology and Immunology
Using biochemical approaches to investigating the trafficking and mechanism of action of the antiviral molecule, IFITM3	Dr Linda Wakim	Microbiology and Immunology
Vaccination against liver-stage Plasmodium for malaria prevention	Professor William (Bill) Heath	Microbiology and Immunology
van Driel laboratory: Immune responses to pathogens	Professor Ian van Driel	Biochemistry and Molecular Biology
Villadangos laboratory: Antigen presenting cells & molecules that initiate T cell immunity against pathogens and cancer	Professor Jose Villadangos	Microbiology and Immunology
Viral interactions with the innate immune system	Associate Professor Patrick Reading	Microbiology and Immunology
Viral tracing to identify central projections and pathways for sensory neurons that innervate bone	Dr Jason Ivanusic	Anatomy and Neuroscience
Visualization and formation West Nile Virus replication complexes	Professor Jason Mackenzie	Microbiology and Immunology
Wakim laboratory: Antiviral molecules, mucosal immunology, influenza virus, tissue resident memory T cells	Dr Linda Wakim	Microbiology and Immunology
West Nile Virus replication and cellular stress responses	Professor Jason Mackenzie	Microbiology and Immunology
What is the function of Sez6L2 in the forebrain?	Dr Jenny Gunnersen Dr Kathryn Munro	Anatomy and Neuroscience
Wilhelm laboratory: Sex determination and disorders of sex development	Associate Professor Dagmar Wilhelm	Anatomy and Neuroscience
Wlodek laboratory: Fetal, postnatal & adult physiology & disease laboratory	Professor Mary Wlodek	Physiology
Wolbachia to stop dengue transmission in Vietnam and Indonesia	Professor Cameron Simmons	Microbiology and Immunology
Young laboratory: Development of the enteric nervous system	Professor Heather Young	Anatomy and Neuroscience

Biomedical Neuroscience

Groups / Projects	Research Lead	Dept / Centre
A simple method to improve stem cell transplant therapy	Dr James Ryall	Physiology
Allen laboratory: Central cardiovascular regulation	Professor Andrew Allen	Physiology
Angiotensin and chemoreceptor function	Professor Andrew Allen	Physiology
Apolipoproteins and amyloid fibril formation in disease	Dr Michael Griffin	Biochemistry and Molecular Biology
Autologous stem cell therapies in Australia	Associate Professor Megan Munsie	Anatomy and Neuroscience
Barrett laboratory: Neural plasticity and neurotrophins	Associate Professor Graham Barrett	Physiology
Biomedical Neuroscience
Blood Atlas: Understanding cell state and differentiation using genomics data from blood cells	Professor Christine Wells	Anatomy and Neuroscience
Bornstein laboratory: Enteric neuroscience	Professor Joel C Bornstein	Physiology
Brain networks processing respiratory sensations	Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Brock laboratory: Autonomic and sensory neuroscience	Associate Professor James Brock	Anatomy and Neuroscience
Can drug-like mimetics of BDNF promote remyelination after injury?	Dr Junhua Xiao	Anatomy and Neuroscience
Cappai laboratory: Alzheimer's disease, prion disease, Parkinson's disease and Traumatic Brain Injury	Professor Roberto Cappai	Pharmacology and Therapeutics
Cell state and cell fate: Systems biology approaches to understanding cell identity	Professor Christine Wells	Anatomy and Neuroscience
Conformational diversity of G-protein coupled receptors and its importance in activation	Associate Professor Paul Gooley	Biochemistry and Molecular Biology
Contemplating stem cells in society	Dr Claire Tanner	Anatomy and Neuroscience
Crack laboratory: Neuropharmacology	Associate Professor Peter Crack	Pharmacology and Therapeutics
Crouch laboratory: Neurodegenerative disease	Dr Peter Crouch	Pharmacology and Therapeutics
De Iongh laboratory: Ocular development laboratory	Associate Professor Robb de Iongh	Anatomy and Neuroscience
Dental morphology	Dr Varsha Pilbrow	Anatomy and Neuroscience
Discovery of polyQ ataxin-1 regulation and regulators	Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Drugs targeting digestive disorders, discovery and proof of principle	Professor John B Furness	Anatomy and Neuroscience
Factors that accelerate photoreceptor death: The role of purines	Professor Erica Fletcher	Anatomy and Neuroscience
Fletcher laboratory: Visual neuroscience	Professor Erica Fletcher	Anatomy and Neuroscience
Furness laboratory: Digestive physiology and nutrition	Professor John Furness	Anatomy and Neuroscience
Glial cells as a source of progenitor cells in degenerative disease	Professor Erica Fletcher	Anatomy and Neuroscience
Gooley laboratory: Structural biology of disease	Associate Professor Paul Gooley	Biochemistry and Molecular Biology
Griffin laboratory: Functional and mis-functional protein-protein interactions	Dr Michael Griffin	Biochemistry and Molecular Biology
Growth factors and peptide mimetics	Dr Susan Northfield	Pharmacology and Therapeutics
Gunnersen laboratory: Neuron development and plasticity	Dr Jenny Gunnersen	Anatomy and Neuroscience
Hatters laboratory: Protein misfolding and proteostasis in neurodegenerative diseases	Associate Professor Danny Hatters	Biochemistry and Molecular Biology
How BDNF signalling controls myelination?	Dr Simon Murray	Anatomy and Neuroscience
How does GM-CSF prevent brain damage after traumatic injury?	Dr Jenny Gunnersen Dr Sandy Shultz	Anatomy and Neuroscience
How does relaxin activate its G-protein coupled receptor?	Associate Professor Paul Gooley	Biochemistry and Molecular Biology
How sensory signals are detected: Structure function relationships in peripheral sensory nerve terminals	Associate Professor James Brock	Anatomy and Neuroscience
Hoyer laboratory: Translational neuroscience	Professor Daniel Hoyer	Pharmacology and Therapeutics
Hughes laboratory: Drug design	Associate Professor Tony Hughes	Pharmacology and Therapeutics
Human brain networks processing respiratory sensations	Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Hypothalamic modulation of basal sympathetic activity	Professor Andrew Allen	Physiology
Improving bladder health after spinal cord injury	Associate Professor James Brock	Anatomy and Neuroscience
Improving recovery of injured visceral nerves and their spinal control centres	Professor Janet Keast	Anatomy and Neuroscience
Innate immunity and neural injury	Associate Professor Peter Crack	Pharmacology and Therapeutics
Is the “shed” form of Sez-6 proteins responsible for their synapse-promoting effects?	Dr Jenny Gunnersen Dr Kathryn Munro	Anatomy and Neuroscience
Ivanusic laboratory: Pain and sensory mechanisms	Dr Jason Ivanusic	Anatomy and Neuroscience
Keast & Osborne laboratory: Neural development, injury and pain	Professor Janet Keast & Dr Peregrine Osborne	Anatomy and Neuroscience
Kilpatrick laboratory: Neuroimmunology of Multiple Sclerosis	Professor Trevor Kilpatrick	Anatomy and Neuroscience
Live cell imaging of neural crest cell migration along the developing gut	Professor Heather Young Professor Heather Young	Anatomy and Neuroscience
Lynch laboratory: Basic and clinical myology	Professor Gordon Lynch	Physiology
Mapping the distribution of angiotensin receptors in the brain	Professor Andrew Allen	Physiology
Mature and developing synaptic transmission between defined classes of enteric neurons	Dr Jaime Foong	Physiology
Mazzone laboratory: Respiratory Sensory Neuroscience	Associate Professor Stuart Mazzone	Anatomy and Neuroscience Research
Measuring Proteostasis Imbalance in Health and Disease	Associate Professor Danny Hatters	Biochemistry and Molecular Biology Research
Mechanisms of growth factor signalling	Dr Simon Murray	Anatomy and Neuroscience
Mechanisms of Toxicity in Huntington's Disease	Associate Professor Danny Hatters	Biochemistry and Molecular Biology
Modelling sensory neuron-epithelial interactions	Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Molecular mechanisms that contribute to bone marrow pain	Dr Jason Ivanusic	Anatomy and Neuroscience
Murray & Xiao laboratory: Neurotrophin and myelin	Dr Simon Murray & Dr Junhua Xiao	Anatomy and Neuroscience
Novel technique to determine the pKA of clonidine at prejunctional α2-adrenoceptors in sympathetic transmission	Professor James Angus	Pharmacology and Therapeutics
Ordidge: Melbourne Brain Centre Imaging Unit	Professor Roger Ordidge	Anatomy and Neuroscience
Oxidative stress and neural injury	Associate Professor Peter Crack	Pharmacology and Therapeutics
Pain management using ultrasound-guided local anaesthetic techniques	Dr Jason Ivanusic	Anatomy and Neuroscience Research
Parker Laboratory: Structural biology and computational drug design	Professor Michael Parker	Biochemistry and Molecular Biology
Patient voices: An analysis of patients’ information-based priorities and needs	Associate Professor Megan Munsie	Anatomy and Neuroscience
Pilbrow laboratory: Physical (biological) anthropology	Dr Varsha Pilbrow	Anatomy and Neuroscience
Potential of cell therapy to treat Hirschsprung’s disease	Professor Heather Young Dr Lincon Stamp	Anatomy and Neuroscience
Probing microtubule organisation	Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Proliferation of enteric neuron precursors	Professor Heather Young Professor Heather Young	Anatomy and Neuroscience
Relaxin family peptide hormones	Associate Professor Tony Hughes	Pharmacology and Therapeutics
Saunders laboratory: Developmental neuroscience and neurotrauma	Professor Norman Saunders	Pharmacology and Therapeutics
Signals for endosomal sorting in development and disease	Professor Paul Gleeson	Biochemistry and Molecular Biology
Skeletal morphology	Dr Varsha Pilbrow	Anatomy and Neuroscience
Stroke	Associate Professor Peter Crack	Pharmacology and Therapeutics
Structural Biology of Cancer	Professor Michael Parker	Biochemistry and Molecular Biology
Structural Biology of Infection	Professor Michael Parker	Biochemistry and Molecular Biology
Structural Neurobiology	Professor Michael Parker	Biochemistry and Molecular Biology
The Enteric Neural Circuitry Activated During Bacterial-toxin Induced Diarrhoea	Dr Jaime Foong	Physiology
The GDNF family, peripheral nerve regeneration and pain	Professor Janet Keast	Anatomy and Neuroscience
The gut hormone, ghrelin, its pharmacology, and the possible application of ghrelin receptor agonists in therapy	Professor John B Furness	Anatomy and Neuroscience
The influence of neurotrophin signalling upon the generation of myelin	Dr Simon Murray	Anatomy and Neuroscience
The link between cardiovascular disease and neurodegeneration – focus on Alzheimer’s disease	Associate Professor Christine Wright	Pharmacology and Therapeutics
The Role of enteric neurons in gastrointestinal symptoms associated with Autism Spectrum disorders	Dr Elisa Hill-Yardin	Physiology
The role of glia in inner retinal changes during retinal degeneration	Professor Erica Fletcher	Anatomy and Neuroscience
The role of glial cells in retinal vascular disease	Professor Erica Fletcher	Anatomy and Neuroscience
The role of microglia in age-related macular degeneration	Professor Erica Fletcher	Anatomy and Neuroscience
The Stemformatics Stem Cell Atlas	Rowland Mosbergen	Anatomy and Neuroscience
The structure of the IL-11 signalling complex	Dr Michael Griffin	Biochemistry and Molecular Biology
The unique features of visceral pain	Professor Janet Keast	Anatomy and Neuroscience
Therapeutic potential of skeletal muscle plasticity and slow muscle programming for muscular dystrophy	Professor Gordon Lynch	Physiology
Transcriptional profiling of sensory neurons	Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Traumatic brain injury	Associate Professor Peter Crack	Pharmacology and Therapeutics
Understanding neuro-urothelial communication	Professor Janet Keast	Anatomy and Neuroscience
Understanding the aetiology of hypertension	Professor Andrew Allen	Physiology
Understanding the cellular cues that direct muscle stem cell specification	Professor Gordon Lynch	Physiology
Understanding the molecular basis of myelin repair	Dr Junhua Xiao	Anatomy and Neuroscience
Understanding the role of angiotensin in the rostral ventrolateral medulla	Professor Andrew Allen	Physiology
Vagal nerve stimulation for the treatment of inflammatory bowel disease	Professor John B Furness	Anatomy and Neuroscience
Viral tracing to identify central projections and pathways for sensory neurons that innervate bone	Dr Jason Ivanusic	Anatomy and Neuroscience
What is the function of Sez6L2 in the forebrain?	Dr Jenny Gunnersen Dr Kathryn Munro	Anatomy and Neuroscience
Young laboratory: Development of the enteric nervous system	Professor Heather Young	Anatomy and Neuroscience

Stem Cells

Groups / Projects	Research Lead	Dept / Centre
A simple method to improve stem cell transplant therapy	Dr James Ryall	Physiology
Analysing genetic roles of RNA-binding proteins and alternative splicing in Drosophila stem cells	Professor Gary Hime	Anatomy and Neuroscience
Autologous stem cell therapies in Australia	Associate Professor Megan Munsie	Anatomy and Neuroscience
Blood Atlas: Understanding cell state and differentiation using genomics data from blood cells	Professor Christine Wells	Anatomy and Neuroscience
Cell state and cell fate: Systems biology approaches to understanding cell identity	Professor Christine Wells	Anatomy and Neuroscience
Cellular trafficking and male fertility	Professor Gary Hime	Anatomy and Neuroscience
Contemplating stem cells in society	Dr Claire Tanner	Anatomy and Neuroscience
EMT regulators in intestinal and germline stem cells	Professor Gary Hime	Anatomy and Neuroscience
Hime laboratory: Stem cell genetics	Professor Gary Hime	Anatomy and Neuroscience
Molecular and cellular analysis of mammalian ovary development and disease	Associate Professor Dagmar Wilhelm	Anatomy and Neuroscience
Munsie laboratory: Ethical, legal and social implications of stem cell research	Associate Professor Megan Munsie	Anatomy and Neuroscience
Novel regulators of germline stem cells	Professor Gary HIme	Anatomy and Neuroscience
Patient voices: An analysis of patients’ information-based priorities and needs	Associate Professor Megan Munsie	Anatomy and Neuroscience
Stem Cells
The Stemformatics Stem Cell Atlas	Rowland Mosbergen	Anatomy and Neuroscience
Transcriptional regulation of intestinal organoid differentiation	Professor Gary Hime	Anatomy and Neuroscience
Understanding the cellular cues that direct muscle stem cell specification	Professor Gordon Lynch	Physiology
Wells laboratory: Stem cell systems	Professor Christine Wells	Anatomy and Neuroscience
Wilhelm laboratory: Sex determination and disorders of sex development	Associate Professor Dagmar Wilhelm	Anatomy and Neuroscience

Systems Biology

Groups / Projects	Research Lead	Dept / Centre
Alternative splicing in human parasites	Dr Stuart Ralph	Biochemistry and Molecular Biology
Application of genomics to public health and clinical microbiology	Professor Ben Howden	Microbiology and Immunology
Australian Venom Research Unit	Dr David Williams	Pharmacology and Therapeutics
Blood Atlas: Understanding cell state and differentiation using genomics data from blood cells	Professor Christine Wells	Anatomy and Neuroscience
Bo&MeRanG Research Projects	Dr Marie Greyer
Cell state and cell fate: Systems biology approaches to understanding cell identity	Professor Christine Wells	Anatomy and Neuroscience
Delbridge laboratory: Cardiac phenomics	Professor Lea Delbridge	Physiology
Diabetic cardiomyopathy – an epidemic disease	Professor Lea Delbridge	Physiology
Drugs targeting digestive disorders, discovery and proof of principle	Professor John B Furness	Anatomy and Neuroscience
Enterococcus faecium	Professor Ben Howden	Microbiology and Immunology
Evolution and spread of drug resistance among bacterial pathogens	A/Prof Kathryn Holt	Biochemistry and Molecular Biology
Global health: Typhoid, dysentery and tuberculosis	A/Prof Kathryn Holt	Biochemistry and Molecular Biology
Gut health in production animals and in human	Professor John B Furness	Anatomy and Neuroscience
Harrap laboratory: Genetic physiology	Professor Stephen Harrap	Physiology
Hatters laboratory: Protein misfolding and proteostasis in neurodegenerative diseases	Associate Professor Danny Hatters	Biochemistry and Molecular Biology
Holt laboratory: Pathogen genomics and bioinformatics	A/Prof Kathryn Holt	Biochemistry and Molecular Biology
Hospital bugs – Klebsiella and Acinetobacter	A/Prof Kathryn Holt	Biochemistry and Molecular Biology
How MR1 molecules present a novel family of antigens to MAIT cells	Dr Hamish McWilliam \| Professor Jose Villadangos	Microbiology and Immunology
Howden laboratory: Molecular epidemiology, genomics and pathogenesis of antimicrobial resistant bacteria	Professor Ben Howden	Microbiology and Immunology
Improving the diagnostic outcomes of patients with mitochondrial disease	Dr David Stroud	Biochemistry and Molecular Biology
Ivanusic laboratory: Pain and sensory mechanisms	Dr Jason Ivanusic	Anatomy and Neuroscience
Molecular mechanisms that contribute to bone marrow pain	Dr Jason Ivanusic	Anatomy and Neuroscience
Mycobacterium ulcerans	Professor TIm Stinear	Microbiology and Immunology
Pain management using ultrasound-guided local anaesthetic techniques	Dr Jason Ivanusic	Anatomy and Neuroscience Research
Respiratory microbiome in infants and children	A/Prof Kathryn Holt	Biochemistry and Molecular Biology
Staphylococcus aureus & Enterococcus faecium	Professor Tim Stinear	Microbiology and Immunology
Staphylococcus aureus and Staphylococcus epidermidis	Professor Ben Howden	Microbiology and Immunology
Steroid hormones and heart failure – sex perspectives	Professor Lea Delbridge	Physiology
Stinear laboratory: Bacterial pathogenomics	Professor Tim Stinear	Microbiology and Immunology
Stroud laboratory: Mitochondrial Systems Biology	Dr David Stroud	Biochemistry and Molecular Biology
Systems Biology
The Cardiovascular Pharmacology of Snake Venoms From Papua New Guinea and Australia	Associate Professor Christine Wright	Pharmacology and Therapeutics
The gut hormone, ghrelin, its pharmacology, and the possible application of ghrelin receptor agonists in therapy	Professor John B Furness	Anatomy and Neuroscience
The roles of gastrointestinal hormones	Professor John B Furness	Anatomy and Neuroscience
The Stemformatics Stem Cell Atlas	Rowland Mosbergen	Anatomy and Neuroscience
The Treatment of Papuan Taipan Envenoming in Papua New Guinea	Dr David Williams	Pharmacology and Therapeutics
Understanding the assembly of mitochondrial machines	Dr David Stroud	Biochemistry and Molecular Biology
Vagal nerve stimulation for the treatment of inflammatory bowel disease	Professor John B Furness	Anatomy and Neuroscience
Viral tracing to identify central projections and pathways for sensory neurons that innervate bone	Dr Jason Ivanusic	Anatomy and Neuroscience
Wells laboratory: Stem cell systems	Professor Christine Wells	Anatomy and Neuroscience

Therapeutics & Translation

Groups / Projects	Research Lead	Dept / Centre
A universal vaccine against influenza A	Professor David Jackson	Microbiology and Immunology
Aminoacyl-tRNA synthetases enzymes as drug targets	Dr Stuart Ralph	Biochemistry and Molecular Biology
Ascher laboratory: Structural biology and bioinformatics	Dr David Ascher	Biochemistry and Molecular Biology
Australian bite and sting trends: Australian Venomous Injury Project (AVIP)	Dr Ronelle Welton	Pharmacology and Therapeutics
Australian Venom Research Unit	Dr David Williams	Pharmacology and Therapeutics
Autologous stem cell therapies in Australia	Associate Professor Megan Munsie	Anatomy and Neuroscience
Autophagy: a Novel Pathway of Antigen Presentation in Dendritic Cells	Professor Jose Villadangos	Microbiology and Immunology
Biolpolymer-based vaccine delivery systems	Professor David Jackson	Microbiology and Immunology
Bo&MeRanG Research Projects	Dr Marie Greyer
Can drug-like mimetics of BDNF promote remyelination after injury?	Dr Junhua Xiao	Anatomy and Neuroscience
Cell biology of membrane receptors regulating the serum half-life of therapeutic proteins	Professor Paul Gleeson	Biochemistry and Molecular Biology
Contemplating stem cells in society	Dr Claire Tanner	Anatomy and Neuroscience
Contribution of proteases to oral cancer pain and metastasis	Dr Laura Edgington-Mitchell	Biochemistry and Molecular Biology
Crack laboratory: Neuropharmacology	Associate Professor Peter Crack	Pharmacology and Therapeutics
Designing better drugs	Dr David Ascher	Biochemistry and Molecular Biology
Developing new therapies for Systemic Lupus Erythematosus	Professor Fabienne Mackay	Microbiology and Immunology
Development of a self-adjuvanting vaccine for enterotoxigenic Escherichia coli (ETEC)	Professor David Jackson	Microbiology and Immunology
Development of antimalarial drugs	Professor Leann Tilley	Biochemistry and Molecular Biology
Development of Novel Chemical Tools to Measure Protease Activation	Dr Laura Edgington-Mitchell	Biochemistry and Molecular Biology
Drug target identification in the malaria parasite	Professor Malcolm McConville	Biochemistry and Molecular Biology
Drugs targeting digestive disorders, discovery and proof of principle	Professor John B Furness	Anatomy and Neuroscience
Edgington-Mitchell laboratory: Protease Pathophysiology	Dr Laura Edgington-Mitchell	Biochemistry and Molecular Biology
Endothelin pharmacology in the setting of pulmonary hypertension	Professor James Angus	Pharmacology and Therapeutics Research
Function of MARCH ubiquitin ligases	Professor Jose Villadangos	Microbiology and Immunology
Furness laboratory: Digestive physiology and nutrition	Professor John Furness	Anatomy and Neuroscience
Gleeson laboratory: Membrane trafficking and protein sorting in health and disease and development of new therapeutics	Professor Paul Gleeson	Biochemistry and Molecular Biology
Gooley laboratory: Structural biology of disease	Associate Professor Paul Gooley	Biochemistry and Molecular Biology
Growth factors and peptide mimetics	Dr Susan Northfield	Pharmacology and Therapeutics
Gut health in production animals and in human	Professor John B Furness	Anatomy and Neuroscience
Harnessing dendritic cells for vaccine development	Professor Jose Villadangos	Microbiology and Immunology
How BDNF signalling controls myelination?	Dr Simon Murray	Anatomy and Neuroscience
Hughes laboratory: Drug design	Associate Professor Tony Hughes	Pharmacology and Therapeutics
Identifying key metabolic pathways required for Toxoplasma gondii infection	Professor Malcolm McConville	Biochemistry and Molecular Biology
Immuno-paralysis following severe infections or trauma	Professor Jose Villadangos	Microbiology and Immunology
Innovative approaches to prepare synthetic, partially synthetic and natural product-based vaccines	Professor David Jackson	Microbiology and Immunology
Ivanusic laboratory: Pain and sensory mechanisms	Dr Jason Ivanusic	Anatomy and Neuroscience
Jackson laboratory: Synthetic vaccine design	Professor David Jackson	Microbiology and Immunology
Joining the immunotherapy revolution: Adoptive cell therapy against cancer	Professor Jose Villadangos	Microbiology and Immunology
Lew laboratory: Theoretical and empirical pharmacology	Dr Michael Lew	Pharmacology and Therapeutics
Lipopeptide-based adjuvanting systems	Professor David Jackson	Microbiology and Immunology
McConville laboratory: Molecular microbiology	Professor Malcolm McConville	Biochemistry and Molecular Biology
Mechanisms of growth factor signalling	Dr Simon Murray	Anatomy and Neuroscience
Molecular mechanisms that contribute to bone marrow pain	Dr Jason Ivanusic	Anatomy and Neuroscience
Munsie laboratory: Ethical, legal and social implications of stem cell research	Associate Professor Megan Munsie	Anatomy and Neuroscience
Murray & Xiao laboratory: Neurotrophin and myelin	Dr Simon Murray & Dr Junhua Xiao	Anatomy and Neuroscience
Pain management using ultrasound-guided local anaesthetic techniques	Dr Jason Ivanusic	Anatomy and Neuroscience Research
Patient voices: An analysis of patients’ information-based priorities and needs	Associate Professor Megan Munsie	Anatomy and Neuroscience
Personalising treatments for genetic diseases	Dr David Ascher	Biochemistry and Molecular Biology
Preclinical pharmacology – cardiovascular efficacy and safety R&D	Associate Professor Christine Wright	Pharmacology and Therapeutics
Protein engineering	Dr David Ascher	Biochemistry and Molecular Biology
Ralph laboratory: Drug targets and gene regulation in Plasmodium falciparum	Dr Stuart Ralph	Biochemistry and Molecular Biology
Relaxin family peptide hormones	Associate Professor Tony Hughes	Pharmacology and Therapeutics
Restoring immunocompetency in Chronic Lymphocytic Leukemia	Professor Fabienne Mackay	Microbiology and Immunology
Tackling drug resistance	Dr David Ascher	Biochemistry and Molecular Biology
The Cardiovascular Pharmacology of Snake Venoms From Papua New Guinea and Australia	Associate Professor Christine Wright	Pharmacology and Therapeutics
The gut hormone, ghrelin, its pharmacology, and the possible application of ghrelin receptor agonists in therapy	Professor John B Furness	Anatomy and Neuroscience
The influence of neurotrophin signalling upon the generation of myelin	Dr Simon Murray	Anatomy and Neuroscience
The link between cardiovascular disease and neurodegeneration – focus on Alzheimer’s disease	Associate Professor Christine Wright	Pharmacology and Therapeutics
The Role of CXCR7 in Tissue Fibrosis	Dr Asolina Braun	Microbiology and Immunology
The role of glucose metabolism and O-GlcNAc glycosylation in the regulation of immunity	Dr Nishma Gupta \| Professor Jose Villadangos	Microbiology and Immunology
The roles of gastrointestinal hormones	Professor John B Furness	Anatomy and Neuroscience
The Treatment of Papuan Taipan Envenoming in Papua New Guinea	Dr David Williams	Pharmacology and Therapeutics
Therapeutics & Translation
Tilley laboratory: Measuring and modelling malaria parasites to develop new antimalarials	Professor Leann Tilley	Biochemistry and Molecular Biology
Trovafloxacin – an antibiotic with additional properties	Professor James Angus	Pharmacology and Therapeutics
Understanding the molecular basis of myelin repair	Dr Junhua Xiao	Anatomy and Neuroscience
Understanding the molecular consequences of mutations	Dr David Ascher	Biochemistry and Molecular Biology
Vagal nerve stimulation for the treatment of inflammatory bowel disease	Professor John B Furness	Anatomy and Neuroscience
Velkov laboratory: Antiinfective pharmacology	Associate Professor Tony Velkov	Pharmacology and Therapeutics
Viral tracing to identify central projections and pathways for sensory neurons that innervate bone	Dr Jason Ivanusic	Anatomy and Neuroscience
Wolbachia to stop dengue transmission in Vietnam and Indonesia	Professor Cameron Simmons	Microbiology and Immunology
Wright laboratory: Cardiovascular Therapeutics Unit	Associate Professor Christine E Wright	Pharmacology and Therapeutics