Biomedical Projects by Theme

Cancer in Biomedicine

Groups / Projects	Research Lead	Dept / Centre
A novel link between metabolism and host defence: O-GlcNAc glycosylation	Professor Jose Villadangos	Biochemistry and Molecular Biology
Analysing protein structures	Dr David Ascher	Biochemistry and Molecular Biology
Barrow laboratory: Tissue immunosurveillance strategies	Head of Laboratory Dr Alexander David Barrow	Microbiology and Immunology
Bo&MeRanG Research Projects	Melbourne Coordinator Dr Marie Greyer
Cancer in Biomedicine
Characterising the pathways responsible for ICU-acquired weakness	Research Project Leader Dr René Koopman	Physiology
Cheng laboratory: Stem cell and organ size control regulation	Head of Laboratory Dr Louise Cheng	Anatomy and Neuroscience
Clinical Proteomics	Project Leader Dr Jonathon Mangum	Pharmacology and Therapeutics
David Ascher laboratory	Head of Laboratory Dr David Ascher	Biochemistry and Molecular Biology
Decoding the trafficking of immune receptors	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Defining new roles for the Hippo signalling pathway in skeletal muscle	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Designing better drugs	Dr David Ascher	Biochemistry and Molecular Biology
Designing new optogenetic tools for biomedical research	A/Prof Danny Hatters	Biochemistry and Molecular Biology
Developing innovative animal and cell culture models to study and treat muscular dystrophies	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Development of effector regulatory T cells	Project Leader Professor Axel Kallies	Microbiology and Immunology
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Research Project Leader Professor Matthew Watt	Physiology
Establishing the effect of glycine/serine metabolism on skeletal muscle cell growth	Research Project Leader Dr René Koopman	Physiology
Exploiting nanoparticles as vaccines	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Exploring new roles for the TGFβ signalling network as a key regulator of skeletal muscle in health and disease	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Finding clarity within a blizzard- guiding the solution of cryo-EM structures	Dr David Ascher	Biochemistry and Molecular Biology
Gavin Reid laboratory	Head of Laboratory Professor Gavin E. Reid	Biochemistry and Molecular Biology
Gregorevic laboratory: Muscle Research and Therapeutics	Head of Laboratory Associate Professor Paul Gregorevic	Physiology
Heung-Chin Cheng laboratory	Head of Laboratory Associate Professor Heung-Chin Cheng	Biochemistry and Molecular Biology
Hime laboratory: Stem cell genetics and Drosophila models of human disease	Head of Laboratory Professor Gary Hime	Anatomy and Neuroscience
Hogan laboratory: Vascular developmental genetics and cell biology	Head of Laboratory Professor Ben Hogan
How do dietary nutrients affect the ability of stem cells and stem cell-derived tumours to grow and divide?	Dr Louise Cheng	Anatomy and Neuroscience
How do neurons maintain their specialised status?	Dr Louise Cheng	Anatomy and Neuroscience
How do tumours compete with other tissues for resources?	Dr Louise Cheng	Anatomy and Neuroscience
How infection and trauma cause dendritic cell paralysis and lethal immunosuppression	Professor Jose Villadangos	Microbiology and Immunology
How to harness the immune system to cure cancer: adoptive cell immunotherapy	Professor Jose Villadangos	Microbiology and Immunology
Immunoregulatory functions of the MARCH family of ubiquitin ligases	Professor Jose Villadangos	Biochemistry and Molecular Biology
Immunosurveillance pathways in brain cancer	Project Leader Dr Alexander David Barrow	Microbiology and Immunology
Investigating the Dystrophin-Glycoprotein Complex to Protect Muscles from Wasting Conditions	Research Project Leader Professor Gordon Lynch	Physiology
Investigating the role of cachexia in the response to surgical tumour resection in mice	Research Project Leader Professor Gordon Lynch	Physiology
Isabelle Rouiller laboratory	Associate Professor Isabelle Rouiller	Biochemistry and Molecular Biology
Kallies laboratory: Molecular immunology	Head of Laboratory Professor Axel Kallies	Microbiology and Immunology
Koopman laboratory: Clinical nutrition and muscle metabolism	Head of Laboratory Dr René Koopman	Physiology
Learning from skeletal muscles to develop new treatments for cancer	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Liz Hinde laboratory	Head of Research Group Dr Elizabeth Hinde	Biochemistry and Molecular Biology
Lynch laboratory: Basic and clinical myology	Head of Laboratory Professor Gordon Lynch	Physiology
Mangum Lab: Translational Proteomics	Head of Laboratory Dr Jonathan Mangum	Pharmacology and Therapeutics
Manipulating immunity to fight infection and tumours	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Mantamadiotis laboratory: Brain Cancer Molecular Biology	Dr Theo Mantamadiotis	Microbiology and Immunology
Marie Bogoyevitch laboratory	Head of Laboratory Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Metabolic reprogramming of skeletal muscle stem cells	Research Project Leader Professor Gordon Lynch	Physiology
Michael Parker laboratory	Head of Laboratory and Director, Bio21 Institute Professor Michael Parker	Biochemistry and Molecular Biology
Molecular basis for growth factor surveillance in natural killer cells	Dr Alexander David Barrow	Microbiology and Immunology
Molecular basis for growth factor surveillance in natural killer cells	Project Leader Dr Alexander David Barrow	Microbiology and Immunology
Molecular basis for growth factor surveillance in plasmacytoid dendritic cells	Project Leader Dr Alexander David Barrow	Microbiology and Immunology
Molecular basis for growth factor surveillance in plasmacytoid dendritic cells	Dr Alexander David Barrow	Microbiology and Immunology
Molecular mechanisms of drug resistance in cancer	Project Leader Dr Jonathon Mangum	Pharmacology and Therapeutics
MR1 – a molecular alarm system that detects pathogen metabolites	Professor Jose Villadangos	Microbiology and Immunology
Mueller laboratory: Visualising the immune system in action	Head of Laboratory Professor Scott Mueller	Microbiology and Immunology
Personalising treatments for genetic diseases	Dr David Ascher	Biochemistry and Molecular Biology
Precursor exhausted T cells in chronic infection and tumors	Project Leader Professor Axel Kallies	Microbiology and Immunology
Pébay laboratory: Stem Cell Disease Modelling	Head of Laboratory Professor Alice Pebay	Anatomy and Neuroscience
Rational Protein Engineering	Dr David Ascher	Biochemistry and Molecular Biology
Resident memory T cells (Trm)	Project Leader Professor Axel Kallies	Microbiology and Immunology
Restoring immunocompetency in Chronic Lymphocytic Leukemia	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
Sex-specific regulation of adipose tissue immune cells	Project Leader Professor Axel Kallies	Microbiology and Immunology
Small molecules for BIG targets- Targeting protein-protein interactions with fragments	Dr David Ascher	Biochemistry and Molecular Biology
Structural Biology of Cancer	Professor Michael Parker	Biochemistry and Molecular Biology
Tackling drug resistance	Dr David Ascher	Biochemistry and Molecular Biology
Taylor: Jack Brockhoff Reconstructive Plastic Surgery Research Unit	Head of Research Unit Professor Ian Taylor	Anatomy and Neuroscience
Therapeutic potential of skeletal muscle plasticity and slow muscle programming for muscular dystrophy	Research Project Leader Professor Gordon Lynch	Physiology
Understanding how the ATPase p97 functions at molecular level	Associate Professor Isabelle Rouiller	Biochemistry and Molecular Biology
Understanding immune dysfunction in acute myeloid leukemia	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Understanding the immune microenvironment in brain tumours	Dr Theo Mantamadiotis	Microbiology and Immunology
Understanding the Molecular Consequences of Mutations	Dr David Ascher David Ascher	Biochemistry and Molecular Biology
Unravelling the mysteries of E3 ubiquitin ligase in regulating skeletal muscle size and function	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Using the immune system to kill tumours	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Using transcriptional analyses to understand recognition of tumours by natural killer cells	Professor Andrew Brooks	Microbiology and Immunology
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Physiology

Cardio-Respiratory

Groups / Projects	Research Lead	Dept / Centre
Allen laboratory: Central cardiovascular regulation	Head of Laboratory Professor Andrew Allen	Physiology
David Stroud laboratory	Head of Research Group Dr David Stroud	Biochemistry and Molecular Biology
Delbridge laboratory: Cardiac phenomics	Head of Laboratory Professor Lea Delbridge	Physiology
Diabetic cardiomyopathy – an epidemic disease	Research Project Leader Professor Lea Delbridge	Physiology
Effects of hypertension on renal and hindquarter vascular reactivity in vivo and in vitro	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
Endothelin pharmacology in the setting of pulmonary hypertension	Project Leader Professor James Angus	Pharmacology and Therapeutics
Functional genomic screens for cardiovascular drug discovery	Research Project Leader Dr Enzo Porrello	Physiology
Improving the diagnostic outcomes of patients with mitochondrial disease	Dr David Stroud	Biochemistry and Molecular Biology
Lung Disease Research Laboratory	Head of Laboratory Professor Gary P Anderson	Pharmacology and Therapeutics
Manipulating the endocannabinoid system to alter cardiovascular function in hypertension	Dr Makhala Khammy	Pharmacology and Therapeutics
Mazzone laboratory: Respiratory Sensory Neuroscience	Head of Research Group Professor Stuart Mazzone	Anatomy and Neuroscience
Mechanisms of diastolic heart failure	Research Project Leader Professor Lea Delbridge	Physiology
Modeling human heart development using human cardiac organoids	Research Project Leader Dr Enzo Porrello	Physiology
Montgomery laboratory: Metabolic Tissue Cross-Talk	Head of Laboratory Dr Magdalene Montgomery	Physiology
Novel technique to determine the pKA of clonidine at prejunctional α2-adrenoceptors in sympathetic transmission	Project Leader Professor James Angus	Pharmacology and Therapeutics
Pathogenesis of chronic lung disease	Head of Laboratory Dr Michelle Hansen	Pharmacology and Therapeutics
Porrello laboratory: Cardiac Regeneration	Head of Laboratory Enzo Porrello	Physiology
Post-natal control of cardiac gene regulatory networks	Research Project Leader Dr Enzo Porrello	Physiology
Preclinical pharmacology – cardiovascular efficacy and safety R&D	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
Reassessment of α1-adrenoceptor mechanism in artery contraction: role of ATP and pannexin channels	Project Leader Professor James Angus	Pharmacology and Therapeutics
Schneider-Futschik laboratory: Cystic Fibrosis pharmacology	Head of Laboratory Dr Elena Schneider-Futschik	Pharmacology and Therapeutics
Sex, adiposity and cardiac vulnerability	Research Project Leader Professor Lea Delbridge	Physiology
Smith laboratory: Cardiac Form and Function	Head of Laboratory Associate Professor Kelly Smith	Physiology
The amyloidogenic protease inhibitor Cystatin C in health and disease	Prof Jose Villadangos	Biochemistry and Molecular Biology
The cardiovascular pharmacology of snake venoms from Papua New Guinea and Australia	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
The innate immune system in the respiratory tract	Project Leader Professor David Jackson	Microbiology and Immunology
The link between cardiovascular disease and neurodegeneration – focus on Alzheimer’s disease	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
Trovafloxacin – an antibiotic with additional properties	Project Leader Professor James Angus	Pharmacology and Therapeutics
Understanding the assembly of mitochondrial machines	Dr David Stroud	Biochemistry and Molecular Biology
Wlodek laboratory: Fetal, postnatal & adult physiology & disease laboratory	Head of Laboratory Professor Mary Wlodek	Physiology
Wright laboratory: Cardiovascular Therapeutics Unit	Head of Laboratory Associate Professor Christine E Wright	Pharmacology and Therapeutics

Cell Signalling

Groups / Projects	Research Lead	Dept / Centre
A new function of the cytokine BAFF in dendritic cell maturation: Implications for immunity and cancers	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
Bedoui laboratory: Innate and adaptive interactions in immunity to infection	Head of Laboratory Professor Sammy Bedoui	Microbiology and Immunology
Bo&MeRanG Research Projects	Melbourne Coordinator Dr Marie Greyer
Cell Signalling
Characterising the pathways responsible for ICU-acquired weakness	Research Project Leader Dr René Koopman	Physiology
Crack laboratory: Neuropharmacology	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Decoding the trafficking of immune receptors	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Defining new roles for the Hippo signalling pathway in skeletal muscle	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Delbridge laboratory: Cardiac phenomics	Head of Laboratory Professor Lea Delbridge	Physiology
Designing new optogenetic tools for biomedical research	A/Prof Danny Hatters	Biochemistry and Molecular Biology
Developing a novel class of therapeutics for muscle wasting and frailty	Research Project Leader Dr Benjamin Parker	Physiology
Developing innovative animal and cell culture models to study and treat muscular dystrophies	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Diabetic cardiomyopathy – an epidemic disease	Research Project Leader Professor Lea Delbridge	Physiology
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Research Project Leader Professor Matthew Watt	Physiology
Establishing the effect of glycine/serine metabolism on skeletal muscle cell growth	Research Project Leader Dr René Koopman	Physiology
Exercise-induced liver-muscle cross-talk and mitochondrial adaptations	Research Project Leader Dr Magdalene Montgomery	Physiology
Exploiting nanoparticles as vaccines	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Exploring new roles for the TGFβ signalling network as a key regulator of skeletal muscle in health and disease	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Gregorevic laboratory: Muscle Research and Therapeutics	Head of Laboratory Associate Professor Paul Gregorevic	Physiology
Gunnersen laboratory: Neuron development and plasticity	Head of Laboratory Dr Jenny Gunnersen	Anatomy and Neuroscience
Heung-Chin Cheng laboratory	Head of Laboratory Associate Professor Heung-Chin Cheng	Biochemistry and Molecular Biology
Hogan laboratory: Vascular developmental genetics and cell biology	Head of Laboratory Professor Ben Hogan
Keast & Osborne laboratory: Neural development, injury and pain	Joint Heads of Laboratory Professor Janet Keast & Dr Peregrine Osborne	Anatomy and Neuroscience
Learning from skeletal muscles to develop new treatments for cancer	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Liz Hinde laboratory	Head of Research Group Dr Elizabeth Hinde	Biochemistry and Molecular Biology
Mantamadiotis laboratory: Brain Cancer Molecular Biology	Dr Theo Mantamadiotis	Microbiology and Immunology
Marie Bogoyevitch laboratory	Head of Laboratory Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Mechanisms of diastolic heart failure	Research Project Leader Professor Lea Delbridge	Physiology
Montgomery laboratory: Metabolic Tissue Cross-Talk	Head of Laboratory Dr Magdalene Montgomery	Physiology
Murray & Xiao laboratory: Neurotrophin and myelin	Joint Heads of Laboratory Dr Simon Murray & Dr Junhua Xiao	Anatomy and Neuroscience
Parker laboratory: Metabolic Proteomics & Signal Transduction	Head of Laboratory Dr Benjamin Parker	Physiology
Paul Gleeson laboratory	Head of Laboratory Professor Paul Gleeson	Biochemistry and Molecular Biology
Sex, adiposity and cardiac vulnerability	Research Project Leader Professor Lea Delbridge	Physiology
Skeletal muscle signal transduction related to exercise, metabolic disease and human health	Research Project Leader Dr Benjamin Parker	Physiology
Smith laboratory: Cardiac Form and Function	Head of Laboratory Associate Professor Kelly Smith	Physiology
Structural Biology of Cancer	Professor Michael Parker	Biochemistry and Molecular Biology
Structural Neurobiology	Professor Michael Parker	Biochemistry and Molecular Biology
Systems genetics of muscle metabolism	Research Project Leader Dr Benjamin Parker	Physiology
The heart as a central player in tissue cross-talk	Research Project Leader Dr Magdalene Montgomery	Physiology
The Role of CXCR7 in Tissue Fibrosis	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
The role of protein modifications on muscle development	Research Project Leader Dr Benjamin Parker	Physiology
Tissue communication in non-alcoholic fatty liver disease (NALFD) and liver fibrosis	Research Project Leader Dr Magdalene Montgomery	Physiology
Understanding immune dysfunction in acute myeloid leukemia	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Understanding metabolic cross-talk in health and disease - Focus on type 2 diabetes and fatty liver	Research Project Leader Dr Magdalene Montgomery	Physiology
Understanding the interaction between microbiota and T cell immunity	Project Leader Professor Sammy Bedoui	Microbiology and Immunology
Unravelling the mysteries of E3 ubiquitin ligase in regulating skeletal muscle size and function	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Using the immune system to kill tumours	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Physiology

Cellular Imaging & Structural Biology

Groups / Projects	Research Lead	Dept / Centre
Adverse maternal environment in females born small and transgenerational consequences	Research Project Leader Professor Mary Wlodek	Physiology
Being born small programs growth restriction, deficits and disease in the next generation	Research Project Leader Professor Mary Wlodek	Physiology
Bo&MeRanG Research Projects	Melbourne Coordinator Dr Marie Greyer
Cellular Imaging & Structural Biology
Danny Hatters laboratory	Head of Laboratory Professor Danny Hatters	Biochemistry and Molecular Biology
Dendritic cell maturation following different microbial stimulation	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Dental morphology	Dr Varsha Pilbrow	Anatomy and Neuroscience
Diana Stojanovski laboratory	Head of Laboratory Dr Diana Stojanovski	Biochemistry and Molecular Biology
Early life exercise reprograms pancreatic and heart deficits in offspring born small	Research Project Leader Professor Mary Wlodek	Physiology
Fletcher laboratory: Visual neuroscience	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
Gunnersen laboratory: Neuron development and plasticity	Head of Laboratory Dr Jenny Gunnersen	Anatomy and Neuroscience
Harnessing local immunity to block the development of secondary bacterial pneumonia	Project Leader Dr Linda Wakim	Microbiology and Immunology
Heath laboratory: CD8 T lymphocytes, dendritic cells, self tolerance and immunity	Head of Laboratory Professor William (Bill) Heath	Microbiology and Immunology
Imaging effector and memory T cell responses in the skin following Herpes Simplex Virus-1 infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Imaging the priming of CD8 Killer T cell responses to Herpes Simplex Virus-1 skin infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Improved vaccines by targeting to dendritic cells	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Intraepithelial T cells in anti-viral immunity	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
Intravital imaging of T cell responses in the brain during cerebral malaria infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Investigating the mechanism of action of the antiviral molecule, IFITM3	Project Leader Dr Linda Wakim	Microbiology and Immunology
Isabelle Rouiller laboratory	Associate Professor Isabelle Rouiller	Biochemistry and Molecular Biology
Keast & Osborne laboratory: Neural development, injury and pain	Joint Heads of Laboratory Professor Janet Keast & Dr Peregrine Osborne	Anatomy and Neuroscience
Leann Tilley laboratory	Head of Laboratory, ARC Australian Laureate Fellow Professor Leann Tilley	Biochemistry and Molecular Biology
Liz Hinde laboratory	Head of Research Group Dr Elizabeth Hinde	Biochemistry and Molecular Biology
Lymphoid stromal cells and control of immunity to infection and cancer	Project Leader Professor Scott Mueller	Microbiology and Immunology
Malaria and Tissue Resident Memory T cells (TRM) in the liver	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Malaria parasite-infected red blood cells: a renovator’s dream	Professor Leann Tilley	Biochemistry and Molecular Biology
Michael Parker laboratory	Head of Laboratory and Director, Bio21 Institute Professor Michael Parker	Biochemistry and Molecular Biology
Mueller laboratory: Visualising the immune system in action	Head of Laboratory Professor Scott Mueller	Microbiology and Immunology
Mummy Studies	Dr Varsha Pilbrow	Anatomy and Neuroscience
Murray & Xiao laboratory: Neurotrophin and myelin	Joint Heads of Laboratory Dr Simon Murray & Dr Junhua Xiao	Anatomy and Neuroscience
Neural regulation of immunity	Project Leader Professor Scott Mueller	Microbiology and Immunology
Paul Gleeson laboratory	Head of Laboratory Professor Paul Gleeson	Biochemistry and Molecular Biology
Paul Gooley laboratory	Head of Laboratory Professor Paul Gooley	Biochemistry and Molecular Biology
Pilbrow laboratory: Physical (biological) anthropology	Head of Laboratory Dr Varsha Pilbrow	Anatomy and Neuroscience
Priming of T cell responses to viral infection	Project Leader Professor Scott Mueller	Microbiology and Immunology
Protein trafficking and cellular architecture	Professor Leann Tilley	Biochemistry and Molecular Biology
Self-tolerance: Interactions between thymic stroma and dendritic cells	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Skeletal morphology	Dr Varsha Pilbrow	Anatomy and Neuroscience
Solving the native structure of the malaria parasite using cryo-electron microscopy	Professor Leann Tilley	Biochemistry and Molecular Biology
T cell responses in the brain during experimental cerebral malaria infection	Project Leader Professor Scott Mueller	Microbiology and Immunology
Taylor: Jack Brockhoff Reconstructive Plastic Surgery Research Unit	Head of Research Unit Professor Ian Taylor	Anatomy and Neuroscience
Tissue-resident memory T cells	Project Leader Professor Scott Mueller	Microbiology and Immunology
Vaccination against liver-stage Plasmodium for malaria prevention	Project Leader Professor William (Bill) Heath	Microbiology and Immunology

Infection & Immunity

Groups / Projects	Research Lead	Dept / Centre
"Clock-off time" for inflammation and remodelling in chronic inflammatory diseases: casein kinase inhibitors	Primary Supervisor Professor Alastair Stewart	Pharmacology and Therapeutics
A cell-based model of sporadic prion disease	Associate Professor Vicki Lawson	Microbiology and Immunology
A new function of the cytokine BAFF in dendritic cell maturation: Implications for immunity and cancers	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
A novel link between metabolism and host defence: O-GlcNAc glycosylation	Professor Jose Villadangos	Biochemistry and Molecular Biology
A universal vaccine against influenza A	Project Leader Professor David Jackson	Microbiology and Immunology
Age-dependent susceptibility of neurons to RNA virus infection	Dr Lukasz Kedzierski	Microbiology and Immunology
Analysing protein structures	Dr David Ascher	Biochemistry and Molecular Biology
Antibodies preventing HTLV-1c infection	Professor Damian Purcell	Microbiology and Immunology
Antibody dependent cellular cytotoxicity - a neglected anti-HIV iImmune response!	Project Leaders Professor Stephen Kent & Dr Amy Chung	Microbiology and Immunology
Antimicrobial resistant bacterial pathogens	Project Leader Professor Ben Howden	Microbiology and Immunology
Application of genomics to public health and clinical microbiology	Project Leader Professor Ben Howden	Microbiology and Immunology
Application of systems genomics to analysing the dynamics of Streptococcus pyogenes infection	Dr Mark Davies	Microbiology and Immunology
Are there additional MAIT cell antigens?	Dr Sidonia Eckle	Microbiology and Immunology
Australian bite and sting trends: Australian Venomous Injury Project (AVIP)	Project Leader Dr Ronelle Welton	Pharmacology and Therapeutics
Australian Venom Research Unit		Pharmacology and Therapeutics
Autophagy and Norovirus replication	Professor Jason Mackenzie	Microbiology and Immunology
Barrow laboratory: Tissue immunosurveillance strategies	Head of Laboratory Dr Alexander David Barrow	Microbiology and Immunology
Bedoui laboratory: Innate and adaptive interactions in immunity to infection	Head of Laboratory Professor Sammy Bedoui	Microbiology and Immunology
Biolpolymer-based vaccine delivery systems	Project Leader Professor David Jackson	Microbiology and Immunology
Blocking the development of secondary bacterial pneumonia	Dr Linda Wakim	Microbiology and Immunology
Bo&MeRanG Research Projects	Melbourne Coordinator Dr Marie Greyer
Brooks laboratory: Innate immunity; anti-viral immunity	Head of Laboratory Professor Andrew Brooks	Microbiology and Immunology
Can resident memory B cells in the lung protect against respiratory syncytial virus?	Professor Stephen Kent	Microbiology and Immunology
CCVs: Clathrin-coated vesicles and Coxiella containing vacuoles	Dr Hayley Newton	Microbiology and Immunology
Cell surface receptors for attachment and entry of influenza virus into cells of the innate immune system	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
Characterisation of antimicrobial resistance and virulence of novel staphylococcal lineages	Associate Professor Steven Tong	Microbiology and Immunology
Characterisation of the changes of the endocytic and secretory pathway of dendritic cells upon activation	Associate Professor Isabelle Rouiller	Biochemistry and Molecular Biology
Characterising the cellular roles of metals	Research Project Leader Associate Professor Christopher McDevitt	Microbiology and Immunology
Chronic immune activation during treated HIV disease	Project Leader Professor Damian Purcell	Microbiology and Immunology
Chung laboratory: Investigating the role of functional antibodies against Mycobacterium tuberculosis	Head of Laboratory Dr Amy Chung	Microbiology and Immunology
Clinical metagenomics for rapid diagnosis of drug resistant tuberculosis	Dr Sarah Dunstan	Microbiology and Immunology
Correlates of severe and fatal influenza disease in high-risk groups	Head of Laboratory Associate Professor Katherine Kedzierska	Microbiology and Immunology
Cow antibodies that give the finger to HIV transmission	Professor Damian Purcell	Microbiology and Immunology
Crack laboratory: Neuropharmacology	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
David Ascher laboratory	Head of Laboratory Dr David Ascher	Biochemistry and Molecular Biology
Deciphering the relative contributions of different dendritic cells to killer T cell responses	Project Leader Professor Sammy Bedoui	Microbiology and Immunology
Decoding the trafficking of immune receptors	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Defining the association between virulence and fitness of seasonal influenza viruses	Professor Kanta Subbarao	Microbiology and Immunology
Defining the impact of recurrent adaptive mutations on staphylococcal antimicrobial resistance and pathogenesis	Professor Ben Howden	Microbiology and Immunology
Delineating how CD4 T cells ‘help’ establishing effective killer T cell responses	Project Leader Professor Sammy Bedoui	Microbiology and Immunology
Dendritic cell maturation following different microbial stimulation	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Design and development of antibiotics against multidrug resistant bacteria	Project Leader Associate Professor Tony Velkov	Pharmacology and Therapeutics
Design of inhibitory drugs for molecular components of the siderophore biosynthetic pathway that are crucial for iron sequestration during mycobacterium tuberculosis (TB) pathogenesis	Project Leader Associate Professor Tony Velkov	Pharmacology and Therapeutics
Design, development and testing of HIV vaccines	Project Leader Professor Damian Purcell	Microbiology and Immunology
Designing better drugs	Dr David Ascher	Biochemistry and Molecular Biology
Designing new optogenetic tools for biomedical research	A/Prof Danny Hatters	Biochemistry and Molecular Biology
Determining the role of diet and microbiota in the progression of lupus	Professor Fabienne Mackay	Microbiology and Immunology
Developing a novel class of therapeutics for muscle wasting and frailty	Research Project Leader Dr Benjamin Parker	Physiology
Developing new therapies for Systemic Lupus Erythematosus	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
Development and application of soft culturing microenvironment for novel drug discovery	Primary Supervisor Professor Alastair Stewart	Pharmacology and Therapeutics
Development and application of soft culturing microenvironment for novel drug discovery	Professor Alastair Stewart	Pharmacology and Therapeutics
Development of a self-adjuvanting vaccine for enterotoxigenic Escherichia coli (ETEC)	Project Leader Professor David Jackson	Microbiology and Immunology
Development of effector regulatory T cells	Project Leader Professor Axel Kallies	Microbiology and Immunology
Development of new types of antimicrobial agents	Project Leader Professor Roy Robins-Browne	Microbiology and Immunology
Development of Novel antimalarial drugs	Professor Leann Tilley	Biochemistry and Molecular Biology
Development of novel proteomic tools to explore Burkholderia pathogenesis	Dr Nichollas Scott	Microbiology and Immunology
Diagnosis, treatment and prevention of medically relevant prion diseases	Associate Professor Vicki Lawson	Microbiology and Immunology
Discovery of malaria vaccine peptide targets	Dr Daniel Fernandez-Ruiz	Microbiology and Immunology
Enterococcus faecium	Project Leader Professor Ben Howden	Microbiology and Immunology
Evolution of streptococcal pathovars	Dr Mark Davies	Microbiology and Immunology
Evolutionary Genetics of avian influenza A viruses in Australia	Dr Michelle Wille	Microbiology and Immunology
Exploiting nanoparticles as vaccines	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Finding clarity within a blizzard- guiding the solution of cryo-EM structures	Dr David Ascher	Biochemistry and Molecular Biology
Furness laboratory: Digestive physiology and nutrition	Head of Laboratory Professor John Furness	Anatomy and Neuroscience
Gamma delta T cells are important for malaria sporozoite vaccination	Dr Lynette Beattie	Microbiology and Immunology
Gebhardt laboratory: Adaptive immune responses to virus infections	Head of Laboratory Professor Thomas Gebhardt	Microbiology and Immunology
Glucocorticoid responsiveness in the lung: impact of inflammation and infection	Professor Alastair Stewart	Pharmacology and Therapeutics
Glucocorticoid responsiveness in the lung: impact of inflammation and infection	Primary Supervisor Professor Alastair Stewart	Pharmacology and Therapeutics
Godfrey laboratory: The development and function of unconventional T cells	Head of Laboratory Professor Dale Godfrey	Microbiology and Immunology
Harnessing local immunity to block the development of secondary bacterial pneumonia	Project Leader Dr Linda Wakim	Microbiology and Immunology
Harnessing the molecular clock to activate diverse strains of latent HIV	Professor Sharon Lewin	Microbiology and Immunology
Harrap laboratory: Genetic physiology	Head of Laboratory Professor Stephen Harrap	Physiology
Heath laboratory: CD8 T lymphocytes, dendritic cells, self tolerance and immunity	Head of Laboratory Professor William (Bill) Heath	Microbiology and Immunology
How do tumours impact normal tissue functions?	Associate Professor Scott Mueller	Microbiology and Immunology
How does ageing effect antibody responses?	Dr Amy Chung	Microbiology and Immunology
How does ageing effect antibody responses?	Project Leader Dr Amy Chung	Microbiology and Immunology
How infection and trauma cause dendritic cell paralysis and lethal immunosuppression	Professor Jose Villadangos	Microbiology and Immunology
How is selective metal ion transport achieved at the host-pathogen interface?	Associate Professor Christopher McDevitt	Microbiology and Immunology
How is the immunological T cell memory generated?	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
How to harness the immune system to cure cancer: adoptive cell immunotherapy	Professor Jose Villadangos	Microbiology and Immunology
Howden laboratory: Molecular epidemiology, genomics and pathogenesis of antimicrobial resistant bacteria	Head of Laboratory \| Director of MDU Professor Ben Howden	Microbiology and Immunology
Ian van Driel laboratory	Head of Laboratory Professor Ian van Driel	Biochemistry and Molecular Biology
Identification and characterisation of novel malarial transmission-blocking antigens	Associate Professor Siddhartha Mahanty	Microbiology and Immunology
Identifying novel subsets of immune cells that control cytomegalovirus following transplantation	Dr Lucy Sullivan	Microbiology and Immunology
Identifying the mechanisms of immune cell development in peripheral tissues	Project Leader Professor Laura Mackay	Microbiology and Immunology
Illuminating microbial “dark matter” for antibiotic discovery	Dr Sacha Pidot	Microbiology and Immunology
Imaging effector and memory T cell responses in the skin following Herpes Simplex Virus-1 infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Imaging the priming of CD8 Killer T cell responses to Herpes Simplex Virus-1 skin infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Immuno-paralysis following severe infections or trauma	Professor Jose Villadangos	Microbiology and Immunology
Immunoregulatory functions of the MARCH family of ubiquitin ligases	Professor Jose Villadangos	Microbiology and Immunology
Immunoregulatory functions of the MARCH family of ubiquitin ligases	Professor Jose Villadangos	Biochemistry and Molecular Biology
Immunosurveillance pathways in brain cancer	Project Leader Dr Alexander David Barrow	Microbiology and Immunology
Improved vaccines by targeting to dendritic cells	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Infection & Immunity
Infection induced changes to splenic macrophages	Dr Lynette Beattie	Microbiology and Immunology
Influenza A virus PB1-F2 Protein: a putative virulence factor and initiator of inflammation	Project Leader Dr Julie McAuley	Microbiology and Immunology
Influenza and HIV vaccines and the importance of mucosal immunity	Project Leader Professor Stephen Kent	Microbiology and Immunology
Influenza–specific ADCC: Role in a universal flu vaccine?	Project Leader Professor Stephen Kent	Microbiology and Immunology
Innate T cell recognition and development	Project Leader Dr Daniel Pellicci	Microbiology and Immunology
Innovative approaches to prepare synthetic, partially synthetic and natural product-based vaccines	Project Leader Professor David Jackson	Microbiology and Immunology
Integrative infectious disease phylodynamics	Dr Sebastian Duchene	Microbiology and Immunology
Intraepithelial T cells in anti-viral immunity	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
Intravital imaging of T cell responses in the brain during cerebral malaria infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Investigating novel chromatin proteins of the malaria parasite P. falciparum as drug targets.	Dr Michael Duffy	Microbiology and Immunology
Investigating the effect of hepatitis B virus splice variants in liver cells and disease progression	Professor Peter Revill	Microbiology and Immunology
Investigating the mechanism of action of the antiviral molecule, IFITM3	Project Leader Dr Linda Wakim	Microbiology and Immunology
Investigating the role of functional antibodies against Mycobacterium tuberculosis	Dr Amy Chung	Microbiology and Immunology
Investigation of HSV latency and reactivation	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
Isabelle Rouiller laboratory	Associate Professor Isabelle Rouiller	Biochemistry and Molecular Biology
Jackson laboratory: Synthetic vaccine design	Head of Laboratory Professor David Jackson	Microbiology and Immunology
Jose Villadangos laboratory	Head of Laboratory Professor Jose Villadangos	Microbiology and Immunology
Justine Mintern laboratory	Head of Laboratory A/Prof Justine Mintern	Biochemistry and Molecular Biology
Kallies laboratory: Molecular immunology	Head of Laboratory Professor Axel Kallies	Microbiology and Immunology
Kedzierska laboratory: Immunity to pandemic and newly emerged influenza viruses	Head of Laboratory Associate Professor Katherine Kedzierska	Microbiology and Immunology
Kent laboratory: HIV vaccines; immune responses to HIV-1; immunotherapy	Head of Laboratory Professor Stephen Kent	Microbiology and Immunology
Klebsiella pneumoniae	Project Leader Professor Dick Strugnell	Microbiology and Immunology
Koopman laboratory: Clinical nutrition and muscle metabolism	Head of Laboratory Dr René Koopman	Physiology
Laura Edgington-Mitchell laboratory	Head of Research Group Dr Laura Edgington-Mitchell	Biochemistry and Molecular Biology
Lawson laboratory: Neurodegenerative disease caused by prions	Head of Laboratory Associate Professor Vicki Lawson	Microbiology and Immunology
Leann Tilley laboratory	Head of Laboratory, ARC Australian Laureate Fellow Professor Leann Tilley	Biochemistry and Molecular Biology
Lew laboratory: Theoretical and empirical pharmacology	Head of Laboratory Dr Michael Lew	Pharmacology and Therapeutics
Lipopeptide-based adjuvanting systems	Project Leader Professor David Jackson	Microbiology and Immunology
Location, location, location – lodging virus specific T cells in the lung as an approach to protecting against influenza virus infection	Dr Linda Wakim	Microbiology and Immunology
Lung Disease Research Laboratory	Head of Laboratory Professor Gary P Anderson	Pharmacology and Therapeutics
Lung Health Research Centre		Pharmacology and Therapeutics
Lymphoid stromal cells and control of immunity to infection and cancer	Project Leader Professor Scott Mueller	Microbiology and Immunology
Mackay (F) laboratory: B lymphocytes, BAFF, autoimmunity and cancer	Head of Laboratory Head of School of Biomedical Sciences Professor Fabienne Mackay	Microbiology and Immunology
Mackay (L) laboratory: Tissue-resident memory T cells; lymphocyte differentiation; peripheral immunity	Senior Lecturer & NHMRC Career Development Fellow, HHMI-Gates International Research Scholar Professor Laura Mackay	Microbiology and Immunology
Mackenzie laboratory: Intracellular virus replication and innate immunity	Head of Laboratory Professor Jason Mackenzie	Microbiology and Immunology
MAIT cells in homeostasis and microbial infections	Researchers Dr Zhenjun Chen, Dr Alexandra Corbett and Dr Sidonia Eckle	Microbiology and Immunology
Malaria and Tissue Resident Memory T cells (TRM) in the liver	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Malaria parasite-infected red blood cells: a renovator’s dream	Professor Leann Tilley	Biochemistry and Molecular Biology
Malcolm McConville laboratory	Head of Laboratory Professor Malcolm McConville	Biochemistry and Molecular Biology
Manipulating immunity to fight infection and tumours	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Manipulating MAIT cells for increased protection by vaccination and therapy	Dr Alexandra Corbett	Microbiology and Immunology
Mapping elemental fluxes during host-pathogen interaction	Associate Professor Christopher McDevitt	Microbiology and Immunology
Marie Bogoyevitch laboratory	Head of Laboratory Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
McCluskey laboratory: Role of MAIT cells in health and disease	Head of Laboratory Redmond Barry Distinguished Professor James McCluskey	Microbiology and Immunology
McDevitt laboratory	Head of Laboratory Associate Professor Christopher McDevitt	Microbiology and Immunology
Mechanisms underlying early generation of human T cell memory	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Memory T cell responses in the lung during virus infection	Project Leader Dr Linda Wakim	Microbiology and Immunology
Metal ion homeostasis in Klebsiella pneumoniae	Associate Professor Christopher McDevitt	Microbiology and Immunology
Michael Parker laboratory	Head of Laboratory and Director, Bio21 Institute Professor Michael Parker	Biochemistry and Molecular Biology
Mitochondria and intracellular bacterial pathogens	Dr Hayley Newton	Microbiology and Immunology
Molecular basis for growth factor surveillance in natural killer cells	Dr Alexander David Barrow	Microbiology and Immunology
Molecular basis for growth factor surveillance in natural killer cells	Project Leader Dr Alexander David Barrow	Microbiology and Immunology
Molecular basis for growth factor surveillance in plasmacytoid dendritic cells	Project Leader Dr Alexander David Barrow	Microbiology and Immunology
Molecular basis for growth factor surveillance in plasmacytoid dendritic cells	Dr Alexander David Barrow	Microbiology and Immunology
MR1 – a molecular alarm system for bacterial infection	Dr Hamish McWilliam	Microbiology and Immunology
MR1 – a molecular alarm system that detects pathogen metabolites	Professor Jose Villadangos	Microbiology and Immunology
Mueller laboratory: Visualising the immune system in action	Head of Laboratory Professor Scott Mueller	Microbiology and Immunology
Munsie laboratory: Ethical, legal and social implications of stem cell research	Head of Laboratory Professor Megan Munsie	Anatomy and Neuroscience
Mycobacterium ulcerans	Project Leader Professor TIm Stinear	Microbiology and Immunology
Nanoparticle Modulation of Mast Cell Function	Project Leader Dr Graham Mackay	Pharmacology and Therapeutics
Neural regulation of anti-cancer immunity	Associate Professor Scott Mueller	Microbiology and Immunology
Neural regulation of immunity	Project Leader Professor Scott Mueller	Microbiology and Immunology
Neurodegeneration in the enteric nervous system	Associate Professor Vicki Lawson	Microbiology and Immunology
New antibiotics from old bacteria	Dr Sacha Pidot	Microbiology and Immunology
Newton laboratory: Virulence strategies of intracellular bacterial pathogens	Head of Laboratory Dr Hayley Newton	Microbiology and Immunology
NK cell receptor biology	Project Leader Professor Andrew Brooks	Microbiology and Immunology
Non-classical MHC and Class 1-like molecules	Project Leader Professor Andrew Brooks	Microbiology and Immunology
Non-conventional T cells and HIV: role of NKT cells, MAIT cells, CD-1 restricted and gamma-delta T cells	Project Leader Professor Stephen Kent	Microbiology and Immunology
Norovirus replication and innate immunity	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
Novel Mast Cell-Derived Mediators	Project Leader Dr Graham Mackay	Pharmacology and Therapeutics
Novel master-regulators of B-cell biology	Professor Fabienne Mackay	Microbiology and Immunology
Passive antibody immunity for use in combination microbicides	Project Leader Professor Damian Purcell	Microbiology and Immunology
Pathogenesis of chronic lung disease	Head of Laboratory Dr Michelle Hansen	Pharmacology and Therapeutics
Pathogenesis of HTLV-1 subtype-C infecting remote indigenous Australians	Professor Damian Purcell	Microbiology and Immunology
Pathogenesis of pneumococcal pneumonia	Associate Professor Catherine Satzke	Microbiology and Immunology
Paul Gleeson laboratory	Head of Laboratory Professor Paul Gleeson	Biochemistry and Molecular Biology
Paul Gooley laboratory	Head of Laboratory Professor Paul Gooley	Biochemistry and Molecular Biology
Plasma protein binding of antibiotics	Project Leader Associate Professor Tony Velkov	Pharmacology and Therapeutics
Population genomics of endemic Streptococcus pyogenes	Dr Mark Davies	Microbiology and Immunology
Precursor exhausted T cells in chronic infection and tumors	Project Leader Professor Axel Kallies	Microbiology and Immunology
Preventing infections of the highly puke-ogenic virus - norovirus	Professor Jason Mackenzie	Microbiology and Immunology
Priming of T cell responses to viral infection	Project Leader Professor Scott Mueller	Microbiology and Immunology
Programming gamma delta T cells for HIV immunotherapy	Professor Stephen Kent	Microbiology and Immunology
Protective capacity of malaria-specific liver-tissue-resident memory T cells	Dr Lauren Holz	Microbiology and Immunology
Protein trafficking and cellular architecture	Professor Leann Tilley	Biochemistry and Molecular Biology
Purcell laboratory: Viral RNA elements, regulation of HIV replication, HIV antibody vaccine	Head of Laboratory Professor Damian Purcell	Microbiology and Immunology
Quantifying bacterial recombination within globally evolving streptococcal pathogens	Dr Mark Davies	Microbiology and Immunology
Rational Protein Engineering	Dr David Ascher	Biochemistry and Molecular Biology
Reading laboratory: Innate immune detection and response to respiratory virus infections	Head of Laboratory Associate Professor Patrick Reading	Microbiology and Immunology
Regeneration of lymphoid tissues	Associate Professor Scot Mueller	Microbiology and Immunology
Regulation of Mast Cell Activation	Project Leader Dr Graham Mackay	Pharmacology and Therapeutics
Resident memory T cells (Trm)	Project Leader Professor Axel Kallies	Microbiology and Immunology
Restoring immunocompetency in Chronic Lymphocytic Leukemia	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
RNA control of HIV latency	Professor Damian Purcell	Microbiology and Immunology
RNA mediated control of HIV-1 gene expression	Project Leader Professor Damian Purcell	Microbiology and Immunology
Robins-Browne laboratory: Medical bacteriology, pathogenesis, bacterial genetics, therapeutics	Head of Laboratory Professor Roy Robins-Browne	Microbiology and Immunology
Role of cellular lipids during Flavivirus replication	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
Role of innate signals in inducing protective T cell immunity	Project Leader Professor Sammy Bedoui	Microbiology and Immunology
Role of O-linked glycosylation system across the Burkholderia genus	Dr Nichollas Scott	Microbiology and Immunology
Role of suppressor of cytokine signalling proteins in viral encephalitis	Dr Lukasz Kedzierski	Microbiology and Immunology
Rutar laboratory: Ocular Neuroimmunology	Head of Laboratory Dr Matt Rutar	Anatomy and Neuroscience
Salmonella Typhimurium	Project Leader Professor Dick Strugnell	Microbiology and Immunology
Schneider-Futschik laboratory: Cystic Fibrosis pharmacology	Head of Laboratory Dr Elena Schneider-Futschik	Pharmacology and Therapeutics
Self-tolerance: Interactions between thymic stroma and dendritic cells	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Sex in human malaria parasites	Dr Matthew Dixon	Biochemistry and Molecular Biology
Sex-specific regulation of adipose tissue immune cells	Project Leader Professor Axel Kallies	Microbiology and Immunology
Skeletal muscle signal transduction related to exercise, metabolic disease and human health	Research Project Leader Dr Benjamin Parker	Physiology
Small molecules for BIG targets- Targeting protein-protein interactions with fragments	Dr David Ascher	Biochemistry and Molecular Biology
SNAP - Staphylococcus aureus Network Adaptive Platform Trial	Associate Professor Steven Tong	Microbiology and Immunology
Soluble barriers to influenza virus infection	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
Solving the native structure of the malaria parasite using cryo-electron microscopy	Professor Leann Tilley	Biochemistry and Molecular Biology
Staphylococcus aureus & Enterococcus faecium	Project Leader Professor Tim Stinear	Microbiology and Immunology
Staphylococcus aureus and Staphylococcus epidermidis	Project Leader Professor Ben Howden	Microbiology and Immunology
Staphylococcus aureus bloodstream infections in Victorian hospitals: regional differences in disease burden and epidemiology	Associate Professor Leon Worth	Microbiology and Immunology
Stewart Laboratory: Mechanopharmacology	Head of Laboratory Professor Alastair Stewart	Pharmacology and Therapeutics
Stinear laboratory: Bacterial pathogenomics	Head of Laboratory Professor Tim Stinear	Microbiology and Immunology
Streptococcal transmission and disease	Associate Professor Catherine Satzke	Microbiology and Immunology
Structural Biology of Infection	Professor Michael Parker	Biochemistry and Molecular Biology
Strugnell laboratory: Bacterial pathogenesis and host responses	Head of Laboratory Professor Dick Strugnell	Microbiology and Immunology
Stuart Ralph laboratory	Head of Laboratory Dr Stuart Ralph	Biochemistry and Molecular Biology
Synergistic and antagonistic interplay between Streptococcus pneumoniae and respiratory viruses	Associate Professor Catherine Satzke	Microbiology and Immunology
Systems genetics of muscle metabolism	Research Project Leader Dr Benjamin Parker	Physiology
T cell responses in the brain during experimental cerebral malaria infection	Project Leader Professor Scott Mueller	Microbiology and Immunology
T cells in peripheral immunity	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
Tackling drug resistance	Dr David Ascher	Biochemistry and Molecular Biology
Testing a novel strategy to target chronic lymphocytic leukemia	Professor Fabienne Mackay	Microbiology and Immunology
The importance of IgA in the protection and control of infectious diseases	Project Leader Dr Amy Chung	Microbiology and Immunology
The importance of IgA in the protection and control of infectious diseases	Dr Amy Chung	Microbiology and Immunology
The innate immune system in the respiratory tract	Project Leader Professor David Jackson	Microbiology and Immunology
The mechanisms of viral escape in murine and human influenza infection	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
The role of CD4+ T cells in viral infections	Project Leader Professor Andrew Brooks	Microbiology and Immunology
The role of co-pathologies in the clinical presentation of prion disease	Associate Professor Vicki Lawson	Microbiology and Immunology
The Role of CXCR7 in Tissue Fibrosis	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
The role of glucose metabolism in the regulation of immunity	Professor Jose Villadangos	Microbiology and Immunology
The role of innate immune cells in protection and pathology during influenza virus infection	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
The role of protein modifications on muscle development	Research Project Leader Dr Benjamin Parker	Physiology
The role of resident memory T cells in barrier immunity and autoimmune disease	Project Leader Professor Laura Mackay	Microbiology and Immunology
The role of the prion protein in brain cancer	Associate Professor Vicki Lawson	Microbiology and Immunology
The roles of metal ions in host-pathogen interaction	Research Project Leader Associate Professor Christopher McDevitt	Microbiology and Immunology
The space of evolutionary trees in infectious disease epidemiology	Dr Sebastian Duchene	Microbiology and Immunology
The Treatment of Papuan Taipan Envenoming in Papua New Guinea	Project Leader Dr David Williams	Pharmacology and Therapeutics
Tissue-resident memory T cells	Project Leader Professor Scott Mueller	Microbiology and Immunology
Tracking phenotypically and functionally distinct T cell subsets via T cell repertoire diversity	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Understanding essential gene regulation in Staphylococcus aureus	Professor Tim Stinear	Microbiology and Immunology
Understanding how Anthrax toxins function	Associate Professor Isabelle Rouiller	Biochemistry and Molecular Biology
Understanding how metal ions traverse bacterial cell membranes	Research Project Leader Associate Professor Christopher McDevitt	Microbiology and Immunology
Understanding immune dysfunction in acute myeloid leukemia	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Understanding the biological chemistry of pneumococcal disease	Associate Professor Christopher McDevitt	Microbiology and Immunology
Understanding the immune microenvironment in brain tumours	Dr Theo Mantamadiotis	Microbiology and Immunology
Understanding the importance of variation in the capsular polysaccharide of Streptococcus pneumoniae	Associate Professor Catherine Satzke	Microbiology and Immunology
Understanding the interaction between microbiota and T cell immunity	Project Leader Professor Sammy Bedoui	Microbiology and Immunology
Understanding the mechanisms that impair anti-tumour adoptive cell therapy	Professor Jose Villadangos	Microbiology and Immunology
Understanding the Molecular Consequences of Mutations	Dr David Ascher David Ascher	Biochemistry and Molecular Biology
Understanding the regulation of tissue-resident memory T cell development	Project Leader Professor Laura Mackay	Microbiology and Immunology
Understanding the role of MAIT cells in immune-mediated pathology	Dr Sidonia Eckle	Microbiology and Immunology
Understanding the role of MAIT cells in protection from microbial infections	Dr Sidonia Eckle	Microbiology and Immunology
Understanding ‘universal’ influenza-specific CD8+ T cell responses	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Unravelling the drivers of scarlet fever pandemics	Dr Mark Davies	Microbiology and Immunology
Using genomics to investigate the transmission of skin pathogens and antimicrobial resistance in a ‘One Health’ setting	Dr Mark Davies	Microbiology and Immunology
Using genomics to track transmission of Chlamydia trachomatis	Dr Hayley Newton	Microbiology and Immunology
Using the immune system to kill tumours	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Using transcriptional analyses to understand recognition of tumours by natural killer cells	Professor Andrew Brooks	Microbiology and Immunology
Vaccination against liver-stage Plasmodium for malaria prevention	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Validating human transgenic mouse models for lupus therapeutics development	Professor Fabienne Mackay	Microbiology and Immunology
Velkov laboratory: Antiinfective pharmacology	Head of Laboratory Associate Professor Tony Velkov	Pharmacology and Therapeutics
Vertical transmission of Ross River virus in mosquito vectors	Dr Julio Rodriguez-Andres	Microbiology and Immunology
Viral interactions with the innate immune system	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
Visualization and formation West Nile Virus replication complexes	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
Wakim laboratory: Antiviral molecules, mucosal immunology, influenza virus, tissue resident memory T cells	Head of Laboratory Dr Linda Wakim	Microbiology and Immunology
Wells laboratory: Stem cell systems	Head of Laboratory Professor Christine Wells	Anatomy and Neuroscience
West Nile Virus replication and cellular stress responses	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
What do antibodies need to do to protect a woman against pregnancy-malaria?	Dr Elizabeth Aitken	Microbiology and Immunology
Whole body analysis of human tissue-resident memory T cells	Dr Claire Gordon	Microbiology and Immunology
Why is the flavivirus RdRp in the nucleus?	Professor Jason Mackenzie	Microbiology and Immunology
Wilkinson-Berka laboratory: Retinal vascular biology and inflammation	Head of Laboratory Professor Jennifer Wilkinson-Berka	Anatomy and Neuroscience
Williamson laboratory: Public health, AMR, epidemiology and microbiology	Head of Laboratory Associate Professor Deborah Williamson	Microbiology and Immunology
“Clock-off time” for inflammation and remodelling in chronic inflammatory diseases: casein kinase inhibitors	Professor Alastair Stewart	Pharmacology and Therapeutics

271

Molecular Mechanisms of Disease

Groups / Projects	Research Lead	Dept / Centre
"Clock-off time" for inflammation and remodelling in chronic inflammatory diseases: casein kinase inhibitors	Primary Supervisor Professor Alastair Stewart	Pharmacology and Therapeutics
A novel link between metabolism and host defence: O-GlcNAc glycosylation	Professor Jose Villadangos	Biochemistry and Molecular Biology
A universal vaccine against influenza A	Project Leader Professor David Jackson	Microbiology and Immunology
Analysing protein structures	Dr David Ascher	Biochemistry and Molecular Biology
Angiotensin and chemoreceptor function	Research Project Leader Professor Andrew Allen	Physiology
Antibody dependent cellular cytotoxicity - a neglected anti-HIV iImmune response!	Project Leaders Professor Stephen Kent & Dr Amy Chung	Microbiology and Immunology
Antimicrobial resistant bacterial pathogens	Project Leader Professor Ben Howden	Microbiology and Immunology
Application of genomics to public health and clinical microbiology	Project Leader Professor Ben Howden	Microbiology and Immunology
Autophagy and Norovirus replication	Professor Jason Mackenzie	Microbiology and Immunology
Bedoui laboratory: Innate and adaptive interactions in immunity to infection	Head of Laboratory Professor Sammy Bedoui	Microbiology and Immunology
Biolpolymer-based vaccine delivery systems	Project Leader Professor David Jackson	Microbiology and Immunology
Bo&MeRanG Research Projects	Melbourne Coordinator Dr Marie Greyer
Bornstein laboratory: Enteric neuroscience	Head of Laboratory Professor Joel C Bornstein	Physiology
Brooks laboratory: Innate immunity; anti-viral immunity	Head of Laboratory Professor Andrew Brooks	Microbiology and Immunology
Can drug-like mimetics of BDNF promote remyelination after injury?	Dr Junhua Xiao	Anatomy and Neuroscience
Cappai laboratory: Neurodegeneration and Brain Injury	Head of Laboratory Professor Roberto Cappai	Pharmacology and Therapeutics
Cell surface receptors for attachment and entry of influenza virus into cells of the innate immune system	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
Characterising the cellular roles of metals	Research Project Leader Associate Professor Christopher McDevitt	Microbiology and Immunology
Characterising the pathways responsible for ICU-acquired weakness	Research Project Leader Dr René Koopman	Physiology
Chronic immune activation during treated HIV disease	Project Leader Professor Damian Purcell	Microbiology and Immunology
Chung laboratory: Investigating the role of functional antibodies against Mycobacterium tuberculosis	Head of Laboratory Dr Amy Chung	Microbiology and Immunology
Clark laboratory: Transcriptomics and Neurogenetics	Head of Laboratory Dr Mike Clark	Anatomy and Neuroscience
Correlates of severe and fatal influenza disease in high-risk groups	Head of Laboratory Associate Professor Katherine Kedzierska	Microbiology and Immunology
Crack laboratory: Neuropharmacology	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Crouch laboratory: Neurodegenerative disease	Head of Laboratory Dr Peter Crouch	Pharmacology and Therapeutics
Danny Hatters laboratory	Head of Laboratory Professor Danny Hatters	Biochemistry and Molecular Biology
David Ascher laboratory	Head of Laboratory Dr David Ascher	Biochemistry and Molecular Biology
David Stroud laboratory	Head of Research Group Dr David Stroud	Biochemistry and Molecular Biology
de Iongh laboratory: Ocular development laboratory	Head of Laboratory Associate Professor Robb de Iongh	Anatomy and Neuroscience
Deciphering the relative contributions of different dendritic cells to killer T cell responses	Project Leader Professor Sammy Bedoui	Microbiology and Immunology
Decoding the trafficking of immune receptors	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Defining new roles for the Hippo signalling pathway in skeletal muscle	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Delbridge laboratory: Cardiac phenomics	Head of Laboratory Professor Lea Delbridge	Physiology
Delineating how CD4 T cells ‘help’ establishing effective killer T cell responses	Project Leader Professor Sammy Bedoui	Microbiology and Immunology
Dendritic cell maturation following different microbial stimulation	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Design, development and testing of HIV vaccines	Project Leader Professor Damian Purcell	Microbiology and Immunology
Developing a novel class of therapeutics for muscle wasting and frailty	Research Project Leader Dr Benjamin Parker	Physiology
Developing innovative animal and cell culture models to study and treat muscular dystrophies	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Developing new therapies for Systemic Lupus Erythematosus	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
Development of a self-adjuvanting vaccine for enterotoxigenic Escherichia coli (ETEC)	Project Leader Professor David Jackson	Microbiology and Immunology
Development of effector regulatory T cells	Project Leader Professor Axel Kallies	Microbiology and Immunology
Development of new types of antimicrobial agents	Project Leader Professor Roy Robins-Browne	Microbiology and Immunology
Diabetic cardiomyopathy – an epidemic disease	Research Project Leader Professor Lea Delbridge	Physiology
Diana Stojanovski laboratory	Head of Laboratory Dr Diana Stojanovski	Biochemistry and Molecular Biology
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Research Project Leader Professor Matthew Watt	Physiology
Dodd laboratory: Metabolic Neuroscience	Head of Laboratory Dr Garron Dodd	Physiology
Enterococcus faecium	Project Leader Professor Ben Howden	Microbiology and Immunology
Establishing the effect of glycine/serine metabolism on skeletal muscle cell growth	Research Project Leader Dr René Koopman	Physiology
Exercise-induced liver-muscle cross-talk and mitochondrial adaptations	Research Project Leader Dr Magdalene Montgomery	Physiology
Exploiting nanoparticles as vaccines	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Exploring new roles for the TGFβ signalling network as a key regulator of skeletal muscle in health and disease	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Fletcher laboratory: Visual neuroscience	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
Furness laboratory: Digestive physiology and nutrition	Head of Laboratory Professor John Furness	Anatomy and Neuroscience
Gavin Reid laboratory	Head of Laboratory Professor Gavin E. Reid	Biochemistry and Molecular Biology
Gebhardt laboratory: Adaptive immune responses to virus infections	Head of Laboratory Professor Thomas Gebhardt	Microbiology and Immunology
Godfrey laboratory: The development and function of unconventional T cells	Head of Laboratory Professor Dale Godfrey	Microbiology and Immunology
Gregorevic laboratory: Muscle Research and Therapeutics	Head of Laboratory Associate Professor Paul Gregorevic	Physiology
Gunnersen laboratory: Neuron development and plasticity	Head of Laboratory Dr Jenny Gunnersen	Anatomy and Neuroscience
Harnessing local immunity to block the development of secondary bacterial pneumonia	Project Leader Dr Linda Wakim	Microbiology and Immunology
Heath laboratory: CD8 T lymphocytes, dendritic cells, self tolerance and immunity	Head of Laboratory Professor William (Bill) Heath	Microbiology and Immunology
Heung-Chin Cheng laboratory	Head of Laboratory Associate Professor Heung-Chin Cheng	Biochemistry and Molecular Biology
Hime laboratory: Stem cell genetics and Drosophila models of human disease	Head of Laboratory Professor Gary Hime	Anatomy and Neuroscience
Hogan laboratory: Vascular developmental genetics and cell biology	Head of Laboratory Professor Ben Hogan
How early life experience influences brain myelination and function late in life?	Dr Junhua Xiao	Anatomy and Neuroscience
How infection and trauma cause dendritic cell paralysis and lethal immunosuppression	Professor Jose Villadangos	Microbiology and Immunology
How is the immunological T cell memory generated?	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Howden laboratory: Molecular epidemiology, genomics and pathogenesis of antimicrobial resistant bacteria	Head of Laboratory \| Director of MDU Professor Ben Howden	Microbiology and Immunology
Hoyer laboratory: Translational neuroscience	Head of Laboratory Head of Department Deputy Head, School of Biomedical Sciences Professor Daniel Hoyer	Pharmacology and Therapeutics
Hypothalamic modulation of basal sympathetic activity	Research Project Leader Professor Andrew Allen	Physiology
Ian van Driel laboratory	Head of Laboratory Professor Ian van Driel	Biochemistry and Molecular Biology
Identifying factors that improve gastrointestinal function in Duchenne's muscular dystrophy	Research Project Leader Professor Gordon Lynch	Physiology
Identifying the mechanisms of immune cell development in peripheral tissues	Project Leader Professor Laura Mackay	Microbiology and Immunology
Imaging effector and memory T cell responses in the skin following Herpes Simplex Virus-1 infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Imaging the priming of CD8 Killer T cell responses to Herpes Simplex Virus-1 skin infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Immunoregulatory functions of the MARCH family of ubiquitin ligases	Professor Jose Villadangos	Biochemistry and Molecular Biology
Improved vaccines by targeting to dendritic cells	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Improving the diagnostic outcomes of patients with mitochondrial disease	Dr David Stroud	Biochemistry and Molecular Biology
Influenza A virus PB1-F2 Protein: a putative virulence factor and initiator of inflammation	Project Leader Dr Julie McAuley	Microbiology and Immunology
Influenza and HIV vaccines and the importance of mucosal immunity	Project Leader Professor Stephen Kent	Microbiology and Immunology
Influenza–specific ADCC: Role in a universal flu vaccine?	Project Leader Professor Stephen Kent	Microbiology and Immunology
Innate immunity and neural injury	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Innate T cell recognition and development	Project Leader Dr Daniel Pellicci	Microbiology and Immunology
Innovative approaches to prepare synthetic, partially synthetic and natural product-based vaccines	Project Leader Professor David Jackson	Microbiology and Immunology
Insulin on the Brain	Research Project Leader Dr Garron Dodd	Physiology
Intraepithelial T cells in anti-viral immunity	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
Intravital imaging of T cell responses in the brain during cerebral malaria infection	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Investigating mechanisms of protein trafficking to human mitochondria	Dr Diana Stojanovski	Biochemistry and Molecular Biology
Investigating the Dystrophin-Glycoprotein Complex to Protect Muscles from Wasting Conditions	Research Project Leader Professor Gordon Lynch	Physiology
Investigating the mechanism of action of the antiviral molecule, IFITM3	Project Leader Dr Linda Wakim	Microbiology and Immunology
Investigating the molecular basis of central myelination and repair	Dr Junhua Xiao	Anatomy and Neuroscience
Investigating the role of cachexia in the response to surgical tumour resection in mice	Research Project Leader Professor Gordon Lynch	Physiology
Investigation of HSV latency and reactivation	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
Ivanusic laboratory: Pain and sensory mechanisms	Head of Laboratory Associate Professor Jason Ivanusic	Anatomy and Neuroscience
Jackson laboratory: Synthetic vaccine design	Head of Laboratory Professor David Jackson	Microbiology and Immunology
Jose Villadangos laboratory	Head of Laboratory Professor Jose Villadangos	Microbiology and Immunology
Justine Mintern laboratory	Head of Laboratory A/Prof Justine Mintern	Biochemistry and Molecular Biology
Kallies laboratory: Molecular immunology	Head of Laboratory Professor Axel Kallies	Microbiology and Immunology
Keast & Osborne laboratory: Neural development, injury and pain	Joint Heads of Laboratory Professor Janet Keast & Dr Peregrine Osborne	Anatomy and Neuroscience
Kedzierska laboratory: Immunity to pandemic and newly emerged influenza viruses	Head of Laboratory Associate Professor Katherine Kedzierska	Microbiology and Immunology
Kent laboratory: HIV vaccines; immune responses to HIV-1; immunotherapy	Head of Laboratory Professor Stephen Kent	Microbiology and Immunology
Kilpatrick laboratory: Neuroimmunology of Multiple Sclerosis	Head of Laboratory Professor Trevor Kilpatrick	Anatomy and Neuroscience
Klebsiella pneumoniae	Project Leader Professor Dick Strugnell	Microbiology and Immunology
Koopman laboratory: Clinical nutrition and muscle metabolism	Head of Laboratory Dr René Koopman	Physiology
Laura Edgington-Mitchell laboratory	Head of Research Group Dr Laura Edgington-Mitchell	Biochemistry and Molecular Biology
Lawson laboratory: Neurodegenerative disease caused by prions	Head of Laboratory Associate Professor Vicki Lawson	Microbiology and Immunology
Learning from skeletal muscles to develop new treatments for cancer	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Lipopeptide-based adjuvanting systems	Project Leader Professor David Jackson	Microbiology and Immunology
Liz Hinde laboratory	Head of Research Group Dr Elizabeth Hinde	Biochemistry and Molecular Biology
Lung Disease Research Laboratory	Head of Laboratory Professor Gary P Anderson	Pharmacology and Therapeutics
Lynch laboratory: Basic and clinical myology	Head of Laboratory Professor Gordon Lynch	Physiology
Mackay (F) laboratory: B lymphocytes, BAFF, autoimmunity and cancer	Head of Laboratory Head of School of Biomedical Sciences Professor Fabienne Mackay	Microbiology and Immunology
Mackay (L) laboratory: Tissue-resident memory T cells; lymphocyte differentiation; peripheral immunity	Senior Lecturer & NHMRC Career Development Fellow, HHMI-Gates International Research Scholar Professor Laura Mackay	Microbiology and Immunology
Mackenzie laboratory: Intracellular virus replication and innate immunity	Head of Laboratory Professor Jason Mackenzie	Microbiology and Immunology
MAIT cells in homeostasis and microbial infections	Researchers Dr Zhenjun Chen, Dr Alexandra Corbett and Dr Sidonia Eckle	Microbiology and Immunology
Malaria and Tissue Resident Memory T cells (TRM) in the liver	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Malcolm McConville laboratory	Head of Laboratory Professor Malcolm McConville	Biochemistry and Molecular Biology
Manipulating immunity to fight infection and tumours	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Mapping the distribution of angiotensin receptors in the brain	Research Project Leader Professor Andrew Allen	Physiology
Mapping the proteome vulnerable to unfolding and aggregation under proteostasis stress	A/Prof Danny Hatters	Biochemistry and Molecular Biology
Marie Bogoyevitch laboratory	Head of Laboratory Associate Professor Marie Bogoyevitch	Biochemistry and Molecular Biology
Mature and developing synaptic transmission between defined classes of enteric neurons	Research Project Leader Dr Jaime Foong	Physiology
Mazzone laboratory: Respiratory Sensory Neuroscience	Head of Research Group Professor Stuart Mazzone	Anatomy and Neuroscience
McCluskey laboratory: Role of MAIT cells in health and disease	Head of Laboratory Redmond Barry Distinguished Professor James McCluskey	Microbiology and Immunology
McDevitt laboratory	Head of Laboratory Associate Professor Christopher McDevitt	Microbiology and Immunology
Mechanisms of diastolic heart failure	Research Project Leader Professor Lea Delbridge	Physiology
Mechanisms underlying early generation of human T cell memory	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Memory T cell responses in the lung during virus infection	Project Leader Dr Linda Wakim	Microbiology and Immunology
Metabolic reprogramming of skeletal muscle stem cells	Research Project Leader Professor Gordon Lynch	Physiology
Michael Parker laboratory	Head of Laboratory and Director, Bio21 Institute Professor Michael Parker	Biochemistry and Molecular Biology
Mike Griffin laboratory	Head of Laboratory Dr Michael Griffin	Biochemistry and Molecular Biology
Molecular Mechanisms of Disease
Montgomery laboratory: Metabolic Tissue Cross-Talk	Head of Laboratory Dr Magdalene Montgomery	Physiology
MR1 – a molecular alarm system that detects pathogen metabolites	Professor Jose Villadangos	Microbiology and Immunology
Murray & Xiao laboratory: Neurotrophin and myelin	Joint Heads of Laboratory Dr Simon Murray & Dr Junhua Xiao	Anatomy and Neuroscience
Mycobacterium ulcerans	Project Leader Professor TIm Stinear	Microbiology and Immunology
Nanoparticle Modulation of Mast Cell Function	Project Leader Dr Graham Mackay	Pharmacology and Therapeutics
Newton laboratory: Virulence strategies of intracellular bacterial pathogens	Head of Laboratory Dr Hayley Newton	Microbiology and Immunology
NK cell receptor biology	Project Leader Professor Andrew Brooks	Microbiology and Immunology
Non-classical MHC and Class 1-like molecules	Project Leader Professor Andrew Brooks	Microbiology and Immunology
Non-conventional T cells and HIV: role of NKT cells, MAIT cells, CD-1 restricted and gamma-delta T cells	Project Leader Professor Stephen Kent	Microbiology and Immunology
Norovirus replication and innate immunity	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
Novel Mast Cell-Derived Mediators	Project Leader Dr Graham Mackay	Pharmacology and Therapeutics
Oxidative stress and neural injury	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Parker laboratory: Metabolic Proteomics & Signal Transduction	Head of Laboratory Dr Benjamin Parker	Physiology
Passive antibody immunity for use in combination microbicides	Project Leader Professor Damian Purcell	Microbiology and Immunology
Paul Gleeson laboratory	Head of Laboratory Professor Paul Gleeson	Biochemistry and Molecular Biology
Paul Gooley laboratory	Head of Laboratory Professor Paul Gooley	Biochemistry and Molecular Biology
Personalising treatments for genetic diseases	Dr David Ascher	Biochemistry and Molecular Biology
Precursor exhausted T cells in chronic infection and tumors	Project Leader Professor Axel Kallies	Microbiology and Immunology
Principles of Peripheral Nerve Myelination	Dr Simon Murray	Anatomy and Neuroscience
Prognostic biomarker and therapeutic target discovery in stroke	Project Leader Dr Jonathon Mangum	Pharmacology and Therapeutics
Purcell laboratory: Viral RNA elements, regulation of HIV replication, HIV antibody vaccine	Head of Laboratory Professor Damian Purcell	Microbiology and Immunology
Reading laboratory: Innate immune detection and response to respiratory virus infections	Head of Laboratory Associate Professor Patrick Reading	Microbiology and Immunology
Regulation of Mast Cell Activation	Project Leader Dr Graham Mackay	Pharmacology and Therapeutics
Resident memory T cells (Trm)	Project Leader Professor Axel Kallies	Microbiology and Immunology
Restoring immunocompetency in Chronic Lymphocytic Leukemia	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
RNA mediated control of HIV-1 gene expression	Project Leader Professor Damian Purcell	Microbiology and Immunology
Robins-Browne laboratory: Medical bacteriology, pathogenesis, bacterial genetics, therapeutics	Head of Laboratory Professor Roy Robins-Browne	Microbiology and Immunology
Role of cellular lipids during Flavivirus replication	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
Role of innate signals in inducing protective T cell immunity	Project Leader Professor Sammy Bedoui	Microbiology and Immunology
Salmonella Typhimurium	Project Leader Professor Dick Strugnell	Microbiology and Immunology
Saunders laboratory: Developmental neuroscience and neurotrauma	Head of Laboratory Professor Norman Saunders	Pharmacology and Therapeutics
Self-tolerance: Interactions between thymic stroma and dendritic cells	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Sex in human malaria parasites	Dr Matthew Dixon	Biochemistry and Molecular Biology
Sex, adiposity and cardiac vulnerability	Research Project Leader Professor Lea Delbridge	Physiology
Sex-specific regulation of adipose tissue immune cells	Project Leader Professor Axel Kallies	Microbiology and Immunology
Skeletal muscle signal transduction related to exercise, metabolic disease and human health	Research Project Leader Dr Benjamin Parker	Physiology
Small molecules for BIG targets- Targeting protein-protein interactions with fragments	Dr David Ascher	Biochemistry and Molecular Biology
Smith laboratory: Cardiac Form and Function	Head of Laboratory Associate Professor Kelly Smith	Physiology
Soluble barriers to influenza virus infection	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
Staphylococcus aureus & Enterococcus faecium	Project Leader Professor Tim Stinear	Microbiology and Immunology
Staphylococcus aureus and Staphylococcus epidermidis	Project Leader Professor Ben Howden	Microbiology and Immunology
Stroke	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Structural Biology of Cancer	Professor Michael Parker	Biochemistry and Molecular Biology
Structural Biology of Infection	Professor Michael Parker	Biochemistry and Molecular Biology
Structural Neurobiology	Professor Michael Parker	Biochemistry and Molecular Biology
Strugnell laboratory: Bacterial pathogenesis and host responses	Head of Laboratory Professor Dick Strugnell	Microbiology and Immunology
Stuart Ralph laboratory	Head of Laboratory Dr Stuart Ralph	Biochemistry and Molecular Biology
Systems genetics of muscle metabolism	Research Project Leader Dr Benjamin Parker	Physiology
T cells in peripheral immunity	Project Leader Professor Francis (Frank) Carbone	Microbiology and Immunology
Tackling drug resistance	Dr David Ascher	Biochemistry and Molecular Biology
The amyloidogenic protease inhibitor Cystatin C in health and disease	Prof Jose Villadangos	Biochemistry and Molecular Biology
The Enteric Neural Circuitry Activated During Bacterial-toxin Induced Diarrhoea	Research Project Leader Dr Jaime Foong	Physiology
The heart as a central player in tissue cross-talk	Research Project Leader Dr Magdalene Montgomery	Physiology
The innate immune system in the respiratory tract	Project Leader Professor David Jackson	Microbiology and Immunology
The mechanisms of viral escape in murine and human influenza infection	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
The role of CD4+ T cells in viral infections	Project Leader Professor Andrew Brooks	Microbiology and Immunology
The Role of CXCR7 in Tissue Fibrosis	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
The Role of enteric neurons in gastrointestinal symptoms associated with Autism Spectrum disorders	Research Project Leader Dr Elisa Hill-Yardin	Physiology
The role of innate immune cells in protection and pathology during influenza virus infection	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
The role of mitochondria in Coxiella burnetii infection	Dr Diana Stojanovski	Biochemistry and Molecular Biology
The role of protein modifications on muscle development	Research Project Leader Dr Benjamin Parker	Physiology
The role of resident memory T cells in barrier immunity and autoimmune disease	Project Leader Professor Laura Mackay	Microbiology and Immunology
The roles of metal ions in host-pathogen interaction	Research Project Leader Associate Professor Christopher McDevitt	Microbiology and Immunology
Therapeutic potential of skeletal muscle plasticity and slow muscle programming for muscular dystrophy	Research Project Leader Professor Gordon Lynch	Physiology
Tissue communication in non-alcoholic fatty liver disease (NALFD) and liver fibrosis	Research Project Leader Dr Magdalene Montgomery	Physiology
Tracking phenotypically and functionally distinct T cell subsets via T cell repertoire diversity	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Traumatic brain injury	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Treating the person not the disease	Dr David Ascher	Biochemistry and Molecular Biology
Understanding how Anthrax toxins function	Associate Professor Isabelle Rouiller	Biochemistry and Molecular Biology
Understanding how membrane-less organelles form with optogenetic tools	A/Prof Danny Hatters	Biochemistry and Molecular Biology
Understanding how metal ions traverse bacterial cell membranes	Research Project Leader Associate Professor Christopher McDevitt	Microbiology and Immunology
Understanding how the ATPase p97 functions at molecular level	Associate Professor Isabelle Rouiller	Biochemistry and Molecular Biology
Understanding immune dysfunction in acute myeloid leukemia	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Understanding metabolic cross-talk in health and disease - Focus on type 2 diabetes and fatty liver	Research Project Leader Dr Magdalene Montgomery	Physiology
Understanding the aetiology of hypertension	Research Project Leader Professor Andrew Allen	Physiology
Understanding the assembly of mitochondrial machines	Dr David Stroud	Biochemistry and Molecular Biology
Understanding the interaction between microbiota and T cell immunity	Project Leader Professor Sammy Bedoui	Microbiology and Immunology
Understanding the Molecular Consequences of Mutations	Dr David Ascher David Ascher	Biochemistry and Molecular Biology
Understanding the regulation of tissue-resident memory T cell development	Project Leader Professor Laura Mackay	Microbiology and Immunology
Understanding the role of angiotensin in the rostral ventrolateral medulla	Research Project Leader Professor Andrew Allen	Physiology
Understanding ‘universal’ influenza-specific CD8+ T cell responses	Project Leader Associate Professor Katherine Kedzierska	Microbiology and Immunology
Unravelling the mysteries of E3 ubiquitin ligase in regulating skeletal muscle size and function	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Using the immune system to kill tumours	A/Prof Justine Mintern	Biochemistry and Molecular Biology
Vaccination against liver-stage Plasmodium for malaria prevention	Project Leader Professor William (Bill) Heath	Microbiology and Immunology
Viral interactions with the innate immune system	Project Leader Associate Professor Patrick Reading	Microbiology and Immunology
Visualization and formation West Nile Virus replication complexes	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
Wakim laboratory: Antiviral molecules, mucosal immunology, influenza virus, tissue resident memory T cells	Head of Laboratory Dr Linda Wakim	Microbiology and Immunology
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Physiology
West Nile Virus replication and cellular stress responses	Project Leader Professor Jason Mackenzie	Microbiology and Immunology
Wilhelm laboratory: Sex determination and disorders of sex development	Head of Laboratory Dr Dagmar Wilhelm	Anatomy and Neuroscience
Wlodek laboratory: Fetal, postnatal & adult physiology & disease laboratory	Head of Laboratory Professor Mary Wlodek	Physiology
“Clock-off time” for inflammation and remodelling in chronic inflammatory diseases: casein kinase inhibitors	Professor Alastair Stewart	Pharmacology and Therapeutics

223

Biomedical Neuroscience

Groups / Projects	Research Lead	Dept / Centre
A gut feeling about new therapies for glioma treatment	Doctor Marlene Hao	Anatomy and Neuroscience
Allen laboratory: Central cardiovascular regulation	Head of Laboratory Professor Andrew Allen	Physiology
Angiotensin and chemoreceptor function	Research Project Leader Professor Andrew Allen	Physiology
Biomedical Neuroscience
Bornstein laboratory: Enteric neuroscience	Head of Laboratory Professor Joel C Bornstein	Physiology
Can drug-like mimetics of BDNF promote remyelination after injury?	Dr Junhua Xiao	Anatomy and Neuroscience
Cappai laboratory: Neurodegeneration and Brain Injury	Head of Laboratory Professor Roberto Cappai	Pharmacology and Therapeutics
Cheng laboratory: Stem cell and organ size control regulation	Head of Laboratory Dr Louise Cheng	Anatomy and Neuroscience
Clark laboratory: Transcriptomics and Neurogenetics	Head of Laboratory Dr Mike Clark	Anatomy and Neuroscience
Crack laboratory: Neuropharmacology	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Crouch laboratory: Neurodegenerative disease	Head of Laboratory Dr Peter Crouch	Pharmacology and Therapeutics
Danny Hatters laboratory	Head of Laboratory Professor Danny Hatters	Biochemistry and Molecular Biology
de Iongh laboratory: Ocular development laboratory	Head of Laboratory Associate Professor Robb de Iongh	Anatomy and Neuroscience
Defining new roles for the Hippo signalling pathway in skeletal muscle	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Dental morphology	Dr Varsha Pilbrow	Anatomy and Neuroscience
Designing new optogenetic tools for biomedical research	A/Prof Danny Hatters	Biochemistry and Molecular Biology
Developing innovative animal and cell culture models to study and treat muscular dystrophies	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Research Project Leader Professor Matthew Watt	Physiology
Exercise-induced liver-muscle cross-talk and mitochondrial adaptations	Research Project Leader Dr Magdalene Montgomery	Physiology
Exploring new roles for the TGFβ signalling network as a key regulator of skeletal muscle in health and disease	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Fletcher laboratory: Visual neuroscience	Head of Laboratory Professor Erica Fletcher	Anatomy and Neuroscience
Fogg laboratory: Surgical Anatomy	Head of Laboratory Associate Professor Quentin Fogg	Anatomy and Neuroscience
Furness laboratory: Digestive physiology and nutrition	Head of Laboratory Professor John Furness	Anatomy and Neuroscience
Genes underlying differentiation of enteric neuronal subtypes	Joint Project Leaders Dr Lincon Stamp	Anatomy and Neuroscience
Gregorevic laboratory: Muscle Research and Therapeutics	Head of Laboratory Associate Professor Paul Gregorevic	Physiology
Growth factors and peptide mimetics	Project Leader Dr Susan Northfield	Pharmacology and Therapeutics
Gunnersen laboratory: Neuron development and plasticity	Head of Laboratory Dr Jenny Gunnersen	Anatomy and Neuroscience
Hogan laboratory: Vascular developmental genetics and cell biology	Head of Laboratory Professor Ben Hogan
How do dietary nutrients affect the ability of stem cells and stem cell-derived tumours to grow and divide?	Dr Louise Cheng	Anatomy and Neuroscience
How do neurons maintain their specialised status?	Dr Louise Cheng	Anatomy and Neuroscience
How do tumours compete with other tissues for resources?	Dr Louise Cheng	Anatomy and Neuroscience
How early life experience influences brain myelination and function late in life?	Dr Junhua Xiao	Anatomy and Neuroscience
Hoyer laboratory: Translational neuroscience	Head of Laboratory Head of Department Deputy Head, School of Biomedical Sciences Professor Daniel Hoyer	Pharmacology and Therapeutics
Hughes & Northfield laboratory: Drug design	Joint Heads of Laboratory Associate Professor Tony Hughes & Dr Susan Northfield	Pharmacology and Therapeutics
Hypothalamic modulation of basal sympathetic activity	Research Project Leader Professor Andrew Allen	Physiology
Identifying factors that improve gastrointestinal function in Duchenne's muscular dystrophy	Research Project Leader Professor Gordon Lynch	Physiology
Innate immunity and neural injury	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Insulin on the Brain	Research Project Leader Dr Garron Dodd	Physiology
Investigating the molecular basis of central myelination and repair	Dr Junhua Xiao	Anatomy and Neuroscience
Isabelle Rouiller laboratory	Associate Professor Isabelle Rouiller	Biochemistry and Molecular Biology
Ivanusic laboratory: Pain and sensory mechanisms	Head of Laboratory Associate Professor Jason Ivanusic	Anatomy and Neuroscience
Keast & Osborne laboratory: Neural development, injury and pain	Joint Heads of Laboratory Professor Janet Keast & Dr Peregrine Osborne	Anatomy and Neuroscience
Kilpatrick laboratory: Neuroimmunology of Multiple Sclerosis	Head of Laboratory Professor Trevor Kilpatrick	Anatomy and Neuroscience
Learning from skeletal muscles to develop new treatments for cancer	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Mapping the distribution of angiotensin receptors in the brain	Research Project Leader Professor Andrew Allen	Physiology
Mapping the proteome vulnerable to unfolding and aggregation under proteostasis stress	A/Prof Danny Hatters	Biochemistry and Molecular Biology
Mature and developing synaptic transmission between defined classes of enteric neurons	Research Project Leader Dr Jaime Foong	Physiology
Mazzone laboratory: Respiratory Sensory Neuroscience	Head of Research Group Professor Stuart Mazzone	Anatomy and Neuroscience
Metabolic activity underlying enteric neurons, glia and progenitors	Dr Marlene Hao	Anatomy and Neuroscience
Michael Parker laboratory	Head of Laboratory and Director, Bio21 Institute Professor Michael Parker	Biochemistry and Molecular Biology
Mike Griffin laboratory	Head of Laboratory Dr Michael Griffin	Biochemistry and Molecular Biology
Montgomery laboratory: Metabolic Tissue Cross-Talk	Head of Laboratory Dr Magdalene Montgomery	Physiology
Mueller laboratory: Visualising the immune system in action	Head of Laboratory Professor Scott Mueller	Microbiology and Immunology
Mummy Studies	Dr Varsha Pilbrow	Anatomy and Neuroscience
Murray & Xiao laboratory: Neurotrophin and myelin	Joint Heads of Laboratory Dr Simon Murray & Dr Junhua Xiao	Anatomy and Neuroscience
Novel technique to determine the pKA of clonidine at prejunctional α2-adrenoceptors in sympathetic transmission	Project Leader Professor James Angus	Pharmacology and Therapeutics
Oxidative stress and neural injury	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Paul Gooley laboratory	Head of Laboratory Professor Paul Gooley	Biochemistry and Molecular Biology
Pilbrow laboratory: Physical (biological) anthropology	Head of Laboratory Dr Varsha Pilbrow	Anatomy and Neuroscience
Potential of stem cell therapy to treat Hirschsprung’s disease	Dr Lincon Stamp	Anatomy and Neuroscience
Principles of Peripheral Nerve Myelination	Dr Simon Murray	Anatomy and Neuroscience
Prognostic biomarker and therapeutic target discovery in stroke	Project Leader Dr Jonathon Mangum	Pharmacology and Therapeutics
Pébay laboratory: Stem Cell Disease Modelling	Head of Laboratory Professor Alice Pebay	Anatomy and Neuroscience
Relaxin family peptide hormones	Project Leader Associate Professor Tony Hughes	Pharmacology and Therapeutics
Rutar laboratory: Ocular Neuroimmunology	Head of Laboratory Dr Matt Rutar	Anatomy and Neuroscience
Saunders laboratory: Developmental neuroscience and neurotrauma	Head of Laboratory Professor Norman Saunders	Pharmacology and Therapeutics
Skeletal morphology	Dr Varsha Pilbrow	Anatomy and Neuroscience
Stamp & Hao laboratory: Development of the enteric nervous system	Joint Heads of Laboratory Dr Lincon Stamp & Dr Marlene Hao	Anatomy and Neuroscience
Stroke	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Structural Neurobiology	Professor Michael Parker	Biochemistry and Molecular Biology
The amyloidogenic protease inhibitor Cystatin C in health and disease	Prof Jose Villadangos	Biochemistry and Molecular Biology
The Enteric Neural Circuitry Activated During Bacterial-toxin Induced Diarrhoea	Research Project Leader Dr Jaime Foong	Physiology
The heart as a central player in tissue cross-talk	Research Project Leader Dr Magdalene Montgomery	Physiology
The link between cardiovascular disease and neurodegeneration – focus on Alzheimer’s disease	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
The Role of enteric neurons in gastrointestinal symptoms associated with Autism Spectrum disorders	Research Project Leader Dr Elisa Hill-Yardin	Physiology
Tissue communication in non-alcoholic fatty liver disease (NALFD) and liver fibrosis	Research Project Leader Dr Magdalene Montgomery	Physiology
Traumatic brain injury	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
Understanding how membrane-less organelles form with optogenetic tools	A/Prof Danny Hatters	Biochemistry and Molecular Biology
Understanding how the ATPase p97 functions at molecular level	Associate Professor Isabelle Rouiller	Biochemistry and Molecular Biology
Understanding metabolic cross-talk in health and disease - Focus on type 2 diabetes and fatty liver	Research Project Leader Dr Magdalene Montgomery	Physiology
Understanding the aetiology of hypertension	Research Project Leader Professor Andrew Allen	Physiology
Understanding the role of angiotensin in the rostral ventrolateral medulla	Research Project Leader Professor Andrew Allen	Physiology
Unravelling the mysteries of E3 ubiquitin ligase in regulating skeletal muscle size and function	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Physiology
Wilkinson-Berka laboratory: Retinal vascular biology and inflammation	Head of Laboratory Professor Jennifer Wilkinson-Berka	Anatomy and Neuroscience

Stem Cells

Groups / Projects	Research Lead	Dept / Centre
A gut feeling about new therapies for glioma treatment	Doctor Marlene Hao	Anatomy and Neuroscience
Cheng laboratory: Stem cell and organ size control regulation	Head of Laboratory Dr Louise Cheng	Anatomy and Neuroscience
Clark laboratory: Transcriptomics and Neurogenetics	Head of Laboratory Dr Mike Clark	Anatomy and Neuroscience
Functional genomic screens for cardiovascular drug discovery	Research Project Leader Dr Enzo Porrello	Physiology
Genes underlying differentiation of enteric neuronal subtypes	Joint Project Leaders Dr Lincon Stamp	Anatomy and Neuroscience
Hime laboratory: Stem cell genetics and Drosophila models of human disease	Head of Laboratory Professor Gary Hime	Anatomy and Neuroscience
How do dietary nutrients affect the ability of stem cells and stem cell-derived tumours to grow and divide?	Dr Louise Cheng	Anatomy and Neuroscience
How do neurons maintain their specialised status?	Dr Louise Cheng	Anatomy and Neuroscience
How do tumours compete with other tissues for resources?	Dr Louise Cheng	Anatomy and Neuroscience
Investigating the Dystrophin-Glycoprotein Complex to Protect Muscles from Wasting Conditions	Research Project Leader Professor Gordon Lynch	Physiology
Investigating the role of cachexia in the response to surgical tumour resection in mice	Research Project Leader Professor Gordon Lynch	Physiology
Lynch laboratory: Basic and clinical myology	Head of Laboratory Professor Gordon Lynch	Physiology
Metabolic activity underlying enteric neurons, glia and progenitors	Dr Marlene Hao	Anatomy and Neuroscience
Metabolic reprogramming of skeletal muscle stem cells	Research Project Leader Professor Gordon Lynch	Physiology
Modeling human heart development using human cardiac organoids	Research Project Leader Dr Enzo Porrello	Physiology
Munsie laboratory: Ethical, legal and social implications of stem cell research	Head of Laboratory Professor Megan Munsie	Anatomy and Neuroscience
Porrello laboratory: Cardiac Regeneration	Head of Laboratory Enzo Porrello	Physiology
Post-natal control of cardiac gene regulatory networks	Research Project Leader Dr Enzo Porrello	Physiology
Potential of stem cell therapy to treat Hirschsprung’s disease	Dr Lincon Stamp	Anatomy and Neuroscience
Pébay laboratory: Stem Cell Disease Modelling	Head of Laboratory Professor Alice Pebay	Anatomy and Neuroscience
Stamp & Hao laboratory: Development of the enteric nervous system	Joint Heads of Laboratory Dr Lincon Stamp & Dr Marlene Hao	Anatomy and Neuroscience
Stem Cells
Therapeutic potential of skeletal muscle plasticity and slow muscle programming for muscular dystrophy	Research Project Leader Professor Gordon Lynch	Physiology
Wells laboratory: Stem cell systems	Head of Laboratory Professor Christine Wells	Anatomy and Neuroscience

Systems Biology

Groups / Projects	Research Lead	Dept / Centre
Application of genomics to public health and clinical microbiology	Project Leader Professor Ben Howden	Microbiology and Immunology
Australian Venom Research Unit		Pharmacology and Therapeutics
Bo&MeRanG Research Projects	Melbourne Coordinator Dr Marie Greyer
Clinical Proteomics	Project Leader Dr Jonathon Mangum	Pharmacology and Therapeutics
Danny Hatters laboratory	Head of Laboratory Professor Danny Hatters	Biochemistry and Molecular Biology
David Stroud laboratory	Head of Research Group Dr David Stroud	Biochemistry and Molecular Biology
Delbridge laboratory: Cardiac phenomics	Head of Laboratory Professor Lea Delbridge	Physiology
Developing a novel class of therapeutics for muscle wasting and frailty	Research Project Leader Dr Benjamin Parker	Physiology
Diabetic cardiomyopathy – an epidemic disease	Research Project Leader Professor Lea Delbridge	Physiology
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Research Project Leader Professor Matthew Watt	Physiology
Enterococcus faecium	Project Leader Professor Ben Howden	Microbiology and Immunology
Exercise-induced liver-muscle cross-talk and mitochondrial adaptations	Research Project Leader Dr Magdalene Montgomery	Physiology
Harrap laboratory: Genetic physiology	Head of Laboratory Professor Stephen Harrap	Physiology
Howden laboratory: Molecular epidemiology, genomics and pathogenesis of antimicrobial resistant bacteria	Head of Laboratory \| Director of MDU Professor Ben Howden	Microbiology and Immunology
Improving the diagnostic outcomes of patients with mitochondrial disease	Dr David Stroud	Biochemistry and Molecular Biology
Investigating mechanisms of protein trafficking to human mitochondria	Dr Diana Stojanovski	Biochemistry and Molecular Biology
Ivanusic laboratory: Pain and sensory mechanisms	Head of Laboratory Associate Professor Jason Ivanusic	Anatomy and Neuroscience
Mechanisms of diastolic heart failure	Research Project Leader Professor Lea Delbridge	Physiology
Montgomery laboratory: Metabolic Tissue Cross-Talk	Head of Laboratory Dr Magdalene Montgomery	Physiology
Mycobacterium ulcerans	Project Leader Professor TIm Stinear	Microbiology and Immunology
Parker laboratory: Metabolic Proteomics & Signal Transduction	Head of Laboratory Dr Benjamin Parker	Physiology
Sex, adiposity and cardiac vulnerability	Research Project Leader Professor Lea Delbridge	Physiology
Skeletal muscle signal transduction related to exercise, metabolic disease and human health	Research Project Leader Dr Benjamin Parker	Physiology
Small molecules for BIG targets- Targeting protein-protein interactions with fragments	Dr David Ascher	Biochemistry and Molecular Biology
Staphylococcus aureus & Enterococcus faecium	Project Leader Professor Tim Stinear	Microbiology and Immunology
Staphylococcus aureus and Staphylococcus epidermidis	Project Leader Professor Ben Howden	Microbiology and Immunology
Stinear laboratory: Bacterial pathogenomics	Head of Laboratory Professor Tim Stinear	Microbiology and Immunology
Systems Biology
Systems genetics of muscle metabolism	Research Project Leader Dr Benjamin Parker	Physiology
The heart as a central player in tissue cross-talk	Research Project Leader Dr Magdalene Montgomery	Physiology
The role of protein modifications on muscle development	Research Project Leader Dr Benjamin Parker	Physiology
The Treatment of Papuan Taipan Envenoming in Papua New Guinea	Project Leader Dr David Williams	Pharmacology and Therapeutics
Tissue communication in non-alcoholic fatty liver disease (NALFD) and liver fibrosis	Research Project Leader Dr Magdalene Montgomery	Physiology
Treating the person not the disease	Dr David Ascher	Biochemistry and Molecular Biology
Understanding metabolic cross-talk in health and disease - Focus on type 2 diabetes and fatty liver	Research Project Leader Dr Magdalene Montgomery	Physiology
Understanding the assembly of mitochondrial machines	Dr David Stroud	Biochemistry and Molecular Biology
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Physiology
Wells laboratory: Stem cell systems	Head of Laboratory Professor Christine Wells	Anatomy and Neuroscience

Therapeutics & Translation

Groups / Projects	Research Lead	Dept / Centre
A universal vaccine against influenza A	Project Leader Professor David Jackson	Microbiology and Immunology
Australian bite and sting trends: Australian Venomous Injury Project (AVIP)	Project Leader Dr Ronelle Welton	Pharmacology and Therapeutics
Australian Venom Research Unit		Pharmacology and Therapeutics
Biolpolymer-based vaccine delivery systems	Project Leader Professor David Jackson	Microbiology and Immunology
Bo&MeRanG Research Projects	Melbourne Coordinator Dr Marie Greyer
Can drug-like mimetics of BDNF promote remyelination after injury?	Dr Junhua Xiao	Anatomy and Neuroscience
Characterising the pathways responsible for ICU-acquired weakness	Research Project Leader Dr René Koopman	Physiology
Crack laboratory: Neuropharmacology	Head of Laboratory Associate Professor Peter Crack	Pharmacology and Therapeutics
David Ascher laboratory	Head of Laboratory Dr David Ascher	Biochemistry and Molecular Biology
Defining new roles for the Hippo signalling pathway in skeletal muscle	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Developing innovative animal and cell culture models to study and treat muscular dystrophies	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Developing new therapies for Systemic Lupus Erythematosus	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
Development of a self-adjuvanting vaccine for enterotoxigenic Escherichia coli (ETEC)	Project Leader Professor David Jackson	Microbiology and Immunology
Development of Novel antimalarial drugs	Professor Leann Tilley	Biochemistry and Molecular Biology
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism	Research Project Leader Professor Matthew Watt	Physiology
Endothelin pharmacology in the setting of pulmonary hypertension	Project Leader Professor James Angus	Pharmacology and Therapeutics
Establishing the effect of glycine/serine metabolism on skeletal muscle cell growth	Research Project Leader Dr René Koopman	Physiology
Exercise-induced liver-muscle cross-talk and mitochondrial adaptations	Research Project Leader Dr Magdalene Montgomery	Physiology
Exploring new roles for the TGFβ signalling network as a key regulator of skeletal muscle in health and disease	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Fogg laboratory: Surgical Anatomy	Head of Laboratory Associate Professor Quentin Fogg	Anatomy and Neuroscience
Furness laboratory: Digestive physiology and nutrition	Head of Laboratory Professor John Furness	Anatomy and Neuroscience
Gregorevic laboratory: Muscle Research and Therapeutics	Head of Laboratory Associate Professor Paul Gregorevic	Physiology
Growth factors and peptide mimetics	Project Leader Dr Susan Northfield	Pharmacology and Therapeutics
How early life experience influences brain myelination and function late in life?	Dr Junhua Xiao	Anatomy and Neuroscience
Hughes & Northfield laboratory: Drug design	Joint Heads of Laboratory Associate Professor Tony Hughes & Dr Susan Northfield	Pharmacology and Therapeutics
Innovative approaches to prepare synthetic, partially synthetic and natural product-based vaccines	Project Leader Professor David Jackson	Microbiology and Immunology
Investigating the molecular basis of central myelination and repair	Dr Junhua Xiao	Anatomy and Neuroscience
Ivanusic laboratory: Pain and sensory mechanisms	Head of Laboratory Associate Professor Jason Ivanusic	Anatomy and Neuroscience
Jackson laboratory: Synthetic vaccine design	Head of Laboratory Professor David Jackson	Microbiology and Immunology
Koopman laboratory: Clinical nutrition and muscle metabolism	Head of Laboratory Dr René Koopman	Physiology
Laura Edgington-Mitchell laboratory	Head of Research Group Dr Laura Edgington-Mitchell	Biochemistry and Molecular Biology
Leann Tilley laboratory	Head of Laboratory, ARC Australian Laureate Fellow Professor Leann Tilley	Biochemistry and Molecular Biology
Learning from skeletal muscles to develop new treatments for cancer	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Lew laboratory: Theoretical and empirical pharmacology	Head of Laboratory Dr Michael Lew	Pharmacology and Therapeutics
Lipopeptide-based adjuvanting systems	Project Leader Professor David Jackson	Microbiology and Immunology
Malcolm McConville laboratory	Head of Laboratory Professor Malcolm McConville	Biochemistry and Molecular Biology
Mangum Lab: Translational Proteomics	Head of Laboratory Dr Jonathan Mangum	Pharmacology and Therapeutics
Molecular mechanisms of drug resistance in cancer	Project Leader Dr Jonathon Mangum	Pharmacology and Therapeutics
Montgomery laboratory: Metabolic Tissue Cross-Talk	Head of Laboratory Dr Magdalene Montgomery	Physiology
Munsie laboratory: Ethical, legal and social implications of stem cell research	Head of Laboratory Professor Megan Munsie	Anatomy and Neuroscience
Murray & Xiao laboratory: Neurotrophin and myelin	Joint Heads of Laboratory Dr Simon Murray & Dr Junhua Xiao	Anatomy and Neuroscience
Paul Gleeson laboratory	Head of Laboratory Professor Paul Gleeson	Biochemistry and Molecular Biology
Paul Gooley laboratory	Head of Laboratory Professor Paul Gooley	Biochemistry and Molecular Biology
Preclinical pharmacology – cardiovascular efficacy and safety R&D	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
Principles of Peripheral Nerve Myelination	Dr Simon Murray	Anatomy and Neuroscience
Prognostic biomarker and therapeutic target discovery in stroke	Project Leader Dr Jonathon Mangum	Pharmacology and Therapeutics
Relaxin family peptide hormones	Project Leader Associate Professor Tony Hughes	Pharmacology and Therapeutics
Restoring immunocompetency in Chronic Lymphocytic Leukemia	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
Schneider-Futschik laboratory: Cystic Fibrosis pharmacology	Head of Laboratory Dr Elena Schneider-Futschik	Pharmacology and Therapeutics
Stewart Laboratory: Mechanopharmacology	Head of Laboratory Professor Alastair Stewart	Pharmacology and Therapeutics
Stuart Ralph laboratory	Head of Laboratory Dr Stuart Ralph	Biochemistry and Molecular Biology
The heart as a central player in tissue cross-talk	Research Project Leader Dr Magdalene Montgomery	Physiology
The link between cardiovascular disease and neurodegeneration – focus on Alzheimer’s disease	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
The Role of CXCR7 in Tissue Fibrosis	Senior Research Officer & Lab Manager Catherine Kennedy, PhD	Microbiology and Immunology
The Treatment of Papuan Taipan Envenoming in Papua New Guinea	Project Leader Dr David Williams	Pharmacology and Therapeutics
Therapeutics & Translation
Tissue communication in non-alcoholic fatty liver disease (NALFD) and liver fibrosis	Research Project Leader Dr Magdalene Montgomery	Physiology
Trovafloxacin – an antibiotic with additional properties	Project Leader Professor James Angus	Pharmacology and Therapeutics
Understanding metabolic cross-talk in health and disease - Focus on type 2 diabetes and fatty liver	Research Project Leader Dr Magdalene Montgomery	Physiology
Unravelling the mysteries of E3 ubiquitin ligase in regulating skeletal muscle size and function	Research Project Leader Associate Professor Paul Gregorevic	Physiology
Velkov laboratory: Antiinfective pharmacology	Head of Laboratory Associate Professor Tony Velkov	Pharmacology and Therapeutics
Watt laboratory: Metabolism and Diabetes	Head of Laboratory Professor Matthew Watt	Physiology
Wilkinson-Berka laboratory: Retinal vascular biology and inflammation	Head of Laboratory Professor Jennifer Wilkinson-Berka	Anatomy and Neuroscience
Williamson laboratory: Public health, AMR, epidemiology and microbiology	Head of Laboratory Associate Professor Deborah Williamson	Microbiology and Immunology
Wright laboratory: Cardiovascular Therapeutics Unit	Head of Laboratory Associate Professor Christine E Wright	Pharmacology and Therapeutics

Scholarship of Teaching and Learning

Groups / Projects	Research Lead	Dept / Centre
Clark: Anatomy, Neuroscience and Cell Biology Education Scholarship	Dr Charlotte Clark	Anatomy and Neuroscience
Heather Verkade: Molecular Biology Education Scholarship	Associate Professor Heather Verkade	Biochemistry and Molecular Biology
Lim: Education Scholarship	Dr Saw Hoon Lim	Biochemistry and Molecular Biology
Mulhern: Biochemistry and Molecular Biology Education Scholarship	Associate Professor Terry Mulhern	Biochemistry and Molecular Biology
Post: Online Teaching Delivery Neuroscience & Anatomy	MSc Ger Post	Anatomy and Neuroscience
Rank: Anatomy Education Scholarship	Dr Michelle Rank	Anatomy and Neuroscience
Scholarship of Teaching and Learning
Waller: Microbiology Education Scholarship	Associate Professor Karena Waller	Microbiology and Immunology
Wijburg: Infection and Immunity Education Scholarship	Associate Professor Odilia Wijburg	Microbiology and Immunology
Willems-Jones: Biochemistry & Molecular Biology Education Scholarship	Dr Amber Willems-Jones	Biochemistry and Molecular Biology