Cheng laboratory: Stem cell and organ size control regulation
Associate Professor Louise Cheng
View Associate Professor Louise Cheng's latest publications listing here
We use the fruit fly Drosophila to study how organ size is maintained and how metabolism can shape organ growth.
We are interested in a number of questions:
- How differentiation is maintained in the developing nervous system
- How the niche surrounding the neural stem cells affect stem cell behaviour
- How one specialized cell type in the CNS can become another through trans-differentiation
- How regeneration is regulated in the CNSs of flies and zebrafish
- How tumours breakdown fat and muscles during cachexia
- How organs communicate with each other to maintain tissue homeostasis
Dr Francesca Froldi, Post Doctoral Researcher
Dr Sofya Golenkina, Post Doctoral Scientist
Dr Callum Dark, Post Doctoral Scientist
Miss Qian Dong, PhD Student
Miss Kellie Veen, PhD Student
Miss Edel Alvarez, PhD Student
Miss Boon Hui Lee, Master Student
Peter MacCallum Cancer Institute
2019-2021 ARC Discovery Project. How neurons maintain their fate. Awarded $455,000
2018-2022 ARC Future Fellowship. Awaking quiescent neural stem cells. Awarded $713,125
2018-2020 NHMRC Project Grant. Metabolic reprogramming of dedifferentiation. Awarded $676,162
2016-2018 NHMRC Project Grant. The Hippo pathway, neural stem cells and brain growth. Awarded $363,136
2016 Peter MacCallum Cancer Institute Foundation Grant. Awarded $55,000
2013-2015 NHMRC Project Grant. How does the tumour suppressor: Nerfin-1 prevents dietary dependent tumour growth. Awarded $609,178
2015 Peter MacCallum Cancer Institute Foundation Grant. Awarded $50,000
- How do neurons maintain their specialised status?
- How do dietary nutrients affect the ability of stem cells and stem cell-derived tumours to grow and divide?
- How do tumours compete for resources to grow?
- How do neural stem cells maintain quiescence?
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For further information about this research, please contact Head of Laboratory Associate Professor Louise Cheng
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