Immunosurveillance pathways in brain cancer
Dr Alexander David Barrow
Growth factor (GF) surveillance is a new mode of cancer immunosurveillance in which the immune system responds to GFs over-expressed by cancers and infected cells. Our work has implicated natural killer (NK) cells and GF surveillance in the control of glioblastoma, a high grade glioma with poor survival. In collaboration with Theo Mantamadiotis’ group, Alex’s group is assessing the role of NK cells and other immune cell subsets in immunosurveillance of the brain using a transgenic mouse model of glioma.
Dr Patrick Constantinescu, Research Officer
Alexander James Sedgwick, Masters student
Yuhan Sun, Masters student
This research project is available to Honours students to join as part of their thesis.
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