Cellular Imaging & Structural Biology

There is considerable expertise in cellular imaging and structural biology in the School which is applied to a wide range of biomedical research programs. Platforms include fluorescence, live imaging, 2-photon imaging, transmission and scanning electron microscopy as well as whole body imaging and imaging mass spectroscopy.

Groups / Projects Research Lead Dept / Centre
Adverse maternal environment in females born small and transgenerational consequences Project Leader Professor Mary Wlodek Physiology
Being born small programs growth restriction, deficits and disease in the next generation Project Leader Professor Mary Wlodek Physiology
Bo&MeRanG Research Projects Melbourne Coordinator Dr Marie Greyer
Brock laboratory: Autonomic and sensory neuroscience Head of Laboratory Associate Professor James Brock
Anatomy and Neuroscience
Can drug-like mimetics of BDNF promote remyelination after injury? Project Leader Dr Junhua Xiao Anatomy and Neuroscience
Dendritic cell maturation following different microbial stimulation Project Leader Professor William (Bill) Heath Microbiology and Immunology
Dental morphology Project Leader Dr Varsha Pilbrow Anatomy and Neuroscience
Early life exercise reprograms pancreatic and heart deficits in offspring born small Project Leader Professor Mary Wlodek Physiology
Factors that accelerate photoreceptor death: The role of purines Head of Laboratory Professor Erica Fletcher Anatomy and Neuroscience
Fletcher laboratory: Visual neuroscience Head of Laboratory Professor Erica Fletcher
Anatomy and Neuroscience
Gleeson laboratory: Membrane trafficking and protein sorting in health and disease and development of new therapeutics Head of Laboratory Professor Paul Gleeson
Biochemistry and Molecular Biology
Glial cells as a source of progenitor cells in degenerative disease Head of Laboratory Professor Erica Fletcher Anatomy and Neuroscience
Gooley laboratory: Structural biology of disease Head of Laboratory Associate Professor Paul Gooley
Biochemistry and Molecular Biology
Gunnersen laboratory: Neuron development and plasticity Head of Laboratory Dr Jenny Gunnersen
Anatomy and Neuroscience
Hatters laboratory: Protein misfolding and proteostasis in neurodegenerative diseases Head of Laboratory Associate Professor Danny Hatters
Biochemistry and Molecular Biology
Heath laboratory: CD8 T lymphocytes, dendritic cells, self tolerance and immunity Head of Laboratory Professor William (Bill) Heath
Microbiology and Immunology
Hinde laboratory: Biophysics of Nuclear Organisation Head of Research Group Dr Elizabeth Hinde
Biochemistry and Molecular Biology
How BDNF signalling controls myelination? Project Leader Dr Simon Murray Anatomy and Neuroscience
How sensory signals are detected: Structure function relationships in peripheral sensory nerve terminals Project Leader Associate Professor James Brock Anatomy and Neuroscience
Imaging effector and memory T cell responses in the skin following Herpes Simplex Virus-1 infection Project Leader Professor William (Bill) Heath Microbiology and Immunology
Imaging the priming of CD8 Killer T cell responses to Herpes Simplex Virus-1 skin infection Project Leader Professor William (Bill) Heath Microbiology and Immunology
Improved vaccines by targeting to dendritic cells Project Leader Professor William (Bill) Heath Microbiology and Immunology
Improving bladder health after spinal cord injury Project Leader Associate Professor James Brock Anatomy and Neuroscience
Intraepithelial T cells in anti-viral immunity Project Leader Professor Francis (Frank) Carbone Microbiology and Immunology
Intravital imaging of T cell responses in the brain during cerebral malaria infection Project Leader Professor William (Bill) Heath Microbiology and Immunology
Keast & Osborne laboratory: Neural development, injury and pain Joint Heads of Laboratory Professor Janet Keast & Dr Peregrine Osborne
Anatomy and Neuroscience
Live cell imaging of neural crest cell migration along the developing gut Head of Laboratory Professor Heather Young
Head of Laboratory Professor Heather Young
Anatomy and Neuroscience
Lymphoid stromal cell responses to infection Project Leader Associate Professor Scott Mueller Microbiology and Immunology
Malaria and Tissue Resident Memory T cells (TRM) in the liver Project Leader Professor William (Bill) Heath Microbiology and Immunology
Mechanisms of growth factor signalling Project Leader Dr Simon Murray Anatomy and Neuroscience
Migration of melanoma cells in the neural crest environment Project Leader Dr Sonja McKeown Anatomy and Neuroscience
Mueller laboratory: Adaptive immune responses to infection, lymphoid stromal cells, and imaging the immune system Head of Laboratory Associate Professor Scott Mueller
Microbiology and Immunology
Murray & Xiao laboratory: Neurotrophin and myelin Joint Heads of Laboratory Dr Simon Murray & Dr Junhua Xiao
Anatomy and Neuroscience
Nervous regulation of T cell migration and anti-viral Immunity Project Leader Associate Professor Scott Mueller Microbiology and Immunology
Parker Laboratory: Structural biology and computational drug design Head of Laboratory and Director, Bio21 Institute Professor Michael Parker
Biochemistry and Molecular Biology
Pilbrow laboratory: Physical (biological) anthropology Head of Laboratory Dr Varsha Pilbrow
Anatomy and Neuroscience
Priming of T cell responses to viral infection Project Leader Associate Professor Scott Mueller Microbiology and Immunology
Rouiller laboratory: Understanding how molecular machines function through cryo-electron microscopy Associate Professor Isabelle Rouiller
Biochemistry and Molecular Biology
Self-tolerance: Interactions between thymic stroma and dendritic cells Project Leader Professor William (Bill) Heath Microbiology and Immunology
Skeletal morphology Project Leader Dr Varsha Pilbrow Anatomy and Neuroscience
Stojanovski laboratory: Mitochondrial biogenesis in health and disease Head of Laboratory Dr Diana Stojanovski
Biochemistry and Molecular Biology
T cell responses in the brain during experimental cerebral malaria infection Project Leader Associate Professor Scott Mueller Microbiology and Immunology
Taylor: Jack Brockhoff Reconstructive Plastic Surgery Research Unit Head of Unit Professor Ian Taylor
Anatomy and Neuroscience
The influence of neurotrophin signalling upon the generation of myelin Project Leader Dr Simon Murray Anatomy and Neuroscience
The role of glia in inner retinal changes during retinal degeneration Head of Laboratory Professor Erica Fletcher Anatomy and Neuroscience
The role of glial cells in retinal vascular disease Head of Laboratory Professor Erica Fletcher Anatomy and Neuroscience
The role of microglia in age-related macular degeneration Head of Laboratory Professor Erica Fletcher Anatomy and Neuroscience
Tilley laboratory: Measuring and modelling malaria parasites to develop new antimalarials Head of Laboratory, ARC Australian Laureate Fellow Professor Leann Tilley
Biochemistry and Molecular Biology
Tissue-resident memory T cells in the skin Project Leader Associate Professor Scott Mueller Microbiology and Immunology
Understanding neuro-urothelial communication Project Leader Professor Janet Keast Anatomy and Neuroscience
Understanding the molecular basis of myelin repair Project Leader Dr Junhua Xiao Anatomy and Neuroscience
Using biochemical approaches to investigating the trafficking and mechanism of action of the antiviral molecule, IFITM3 Project Leader Dr Linda Wakim Microbiology and Immunology
Vaccination against liver-stage Plasmodium for malaria prevention Project Leader Professor William (Bill) Heath Microbiology and Immunology

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