A gut feeling about new therapies for glioma

• 
  Joint Project Leaders
  Dr Lincon Stamp & Dr Marlene Hao

  lstamp@unimelb.edu.au, hao.m@unimelb.edu.au

  +61 3 8344 5770 (LS), +61 3 8344 0007 (MH)

Project Details

Gliomas are a very aggressive form of brain cancer, with a very poor 5-year survival rate. Gliomas can arise from over-proliferation of glial cells or stem cells in the brain. Glial cells are a prominent part of the enteric nervous system in the gut.

In this project, we will use a novel line of transgenic mice to investigate gene expression patterns between glial cells in the brain and the gut using RNA-sequencing technology and bioinformatic analysis.

Researchers

Dr Lincon Stamp, ARC DECRA Fellow

Dr Marlene Hao, ARC DECRA Fellow

Ms Annette Bergner, Senior Research Assistant

Yvette Wilson, Research Assistant

Collaborators

Dr Theo Mantamadiotis, University of Melbourne

Research Opportunities

This research project is available to Honours students to join as part of their thesis.
Please contact the Research Group Leader to discuss your options.

Research Outcomes

Hao MM, Foong JP, Bornstein JC, Li ZL, Vanden Berghe P, Boesmans W. Enteric nervous system assembly: Functional integration within the developing gut. Dev Biol. 2016; 417:168-81.

Hao MM, Young HM. Development of enteric neuron diversity. J Cell Mol Med. 2009; 13:1193-210.