Biomedical Neuroscience

Our research programs in neuroscience, cell and developmental biology, and anatomical sciences aim to understand fundamental biological mechanisms in order to develop new treatments for injury and disease states.

Groups / Projects Research Lead Dept / Centre
Allen laboratory: Central cardiovascular regulation Head of Laboratory Professor Andrew Allen
Physiology
Angiotensin and chemoreceptor function Research Project Leader Professor Andrew Allen
Physiology
Applications of Nanopore sequencing Project Leader Dr Mike Clark Anatomy and Neuroscience
Autologous stem cell therapies in Australia Project Leader Associate Professor Megan Munsie Anatomy and Neuroscience
Blood Atlas: Understanding cell state and differentiation using genomics data from blood cells Project Leader Professor Christine Wells Anatomy and Neuroscience
Bornstein laboratory: Enteric neuroscience Head of Laboratory Professor Joel C Bornstein
Physiology
Brain networks processing respiratory sensations Project Leader Associate Professor Stuart Mazzone Anatomy and Neuroscience
Brock laboratory: Autonomic and sensory neuroscience Head of Laboratory Associate Professor James Brock
Anatomy and Neuroscience
Can drug-like mimetics of BDNF promote remyelination after injury? Project Leader Dr Junhua Xiao Anatomy and Neuroscience
Cappai laboratory: Neurodegeneration and Brain Injury Head of Laboratory Professor Roberto Cappai
Pharmacology and Therapeutics
Cell state and cell fate: Systems biology approaches to understanding cell identity Project Leader Professor Christine Wells Anatomy and Neuroscience
Cheng laboratory: Stem cell and organ size control regulation Head of Laboratory Dr Louise Cheng
Physiology
Clark laboratory: Transcriptomics and Neurogenetics Head of Laboratory Dr Mike Clark
Anatomy and Neuroscience
Contemplating stem cells in society Project Leader Dr Claire Tanner Anatomy and Neuroscience
Crack laboratory: Neuropharmacology Head of Laboratory Associate Professor Peter Crack
Pharmacology and Therapeutics
Crouch laboratory: Neurodegenerative disease Head of Laboratory Dr Peter Crouch
Pharmacology and Therapeutics
De Iongh laboratory: Ocular development laboratory Head of Laboratory Associate Professor Robb de Iongh
Anatomy and Neuroscience
Defining new roles for the Hippo signalling pathway in skeletal muscle Research Project Leader Associate Professor Paul Gregorevic
Physiology
Dental morphology Project Leader Dr Varsha Pilbrow Anatomy and Neuroscience
Designing new optogenetic tools for biomedical research A/Prof Danny Hatters Biochemistry and Molecular Biology
Developing innovative animal and cell culture models to study and treat muscular dystrophies Research Project Leader Associate Professor Paul Gregorevic
Physiology
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism Research Project Leader Professor Matthew Watt
Physiology
Exercise-induced liver-muscle cross-talk and mitochondrial adaptations Research Project Leader Dr Magdalene Montgomery
Physiology
Exploring new roles for the TGFβ signalling network as a key regulator of skeletal muscle in health and disease Research Project Leader Associate Professor Paul Gregorevic
Physiology
Factors that accelerate photoreceptor death: The role of purines Head of Laboratory Professor Erica Fletcher Anatomy and Neuroscience
Fletcher laboratory: Visual neuroscience Head of Laboratory Professor Erica Fletcher
Anatomy and Neuroscience
Furness laboratory: Digestive physiology and nutrition Head of Laboratory Professor John Furness
Anatomy and Neuroscience
Glial cells as a source of progenitor cells in degenerative disease Head of Laboratory Professor Erica Fletcher Anatomy and Neuroscience
Gooley laboratory: Structural biology of disease Head of Laboratory Associate Professor Paul Gooley
Biochemistry and Molecular Biology
Gregorevic laboratory: Muscle Research and Therapeutics Head of Laboratory Associate Professor Paul Gregorevic
Physiology
Griffin laboratory: Functional and mis-functional protein-protein interactions Head of Laboratory Dr Michael Griffin
Biochemistry and Molecular Biology
Growth factors and peptide mimetics Project Leader Dr Susan Northfield Pharmacology and Therapeutics
Gunnersen laboratory: Neuron development and plasticity Head of Laboratory Dr Jenny Gunnersen
Anatomy and Neuroscience
Hatters laboratory: Protein misfolding and proteostasis in neurodegenerative diseases Head of Laboratory Associate Professor Danny Hatters
Biochemistry and Molecular Biology
How BDNF signalling controls myelination? Project Leader Dr Simon Murray Anatomy and Neuroscience
How do dietary nutrients affect the ability of stem cells and stem cell-derived tumours to grow and divide? Research Project Leader Dr Louise Cheng
Anatomy and Neuroscience Research
How do neurons maintain their specialised status? Research Project Leader Dr Louise Cheng
Physiology
How do tumours compete with other tissues for resources? Research Project Leader Dr Louise Cheng
Physiology
How does GM-CSF prevent brain damage after traumatic injury? Head of Laboratory Dr Jenny Gunnersen
Project Leader Dr Sandy Shultz
Anatomy and Neuroscience
How sensory signals are detected: Structure function relationships in peripheral sensory nerve terminals Project Leader Associate Professor James Brock Anatomy and Neuroscience
Hoyer laboratory: Translational neuroscience Head of Laboratory
Head of Department
Deputy Head, School of Biomedical Sciences Professor Daniel Hoyer

Pharmacology and Therapeutics
Hughes & Northfield laboratory: Drug design Joint Heads of Laboratory Associate Professor Tony Hughes & Dr Susan Northfield
Pharmacology and Therapeutics
Human brain networks processing respiratory sensations Project Leader Associate Professor Stuart Mazzone Anatomy and Neuroscience
Hypothalamic modulation of basal sympathetic activity Research Project Leader Professor Andrew Allen
Physiology
Improving bladder health after spinal cord injury Project Leader Associate Professor James Brock Anatomy and Neuroscience
Improving recovery of injured visceral nerves and their spinal control centres Project Leader Professor Janet Keast Anatomy and Neuroscience
Innate immunity and neural injury Head of Laboratory Associate Professor Peter Crack Pharmacology and Therapeutics
Insulin on the Brain Research Project Leader Dr Garron Dodd
Physiology
Is the “shed” form of Sez-6 proteins responsible for their synapse-promoting effects? Head of Laboratory Dr Jenny Gunnersen
Project Leader Dr Kathryn Munro
Anatomy and Neuroscience
Ivanusic laboratory: Pain and sensory mechanisms Head of Laboratory Dr Jason Ivanusic
Anatomy and Neuroscience
Kilpatrick laboratory: Neuroimmunology of Multiple Sclerosis Head of Laboratory Professor Trevor Kilpatrick
Anatomy and Neuroscience
Learning from skeletal muscles to develop new treatments for cancer Research Project Leader Associate Professor Paul Gregorevic
Physiology
Live cell imaging of neural crest cell migration along the developing gut Head of Laboratory Professor Heather Young
Head of Laboratory Professor Heather Young
Anatomy and Neuroscience
Lynch laboratory: Basic and clinical myology Head of Laboratory Professor Gordon Lynch
Physiology
Mapping the distribution of angiotensin receptors in the brain Research Project Leader Professor Andrew Allen
Physiology
Mapping the proteome vulnerable to unfolding and aggregation under proteostasis stress A/Prof Danny Hatters Biochemistry and Molecular Biology
Mature and developing synaptic transmission between defined classes of enteric neurons Research Project Leader Dr Jaime Foong
Physiology
Mazzone laboratory: Respiratory Sensory Neuroscience Head of Research Group Associate Professor Stuart Mazzone
Anatomy and Neuroscience
Mechanisms of growth factor signalling Project Leader Dr Simon Murray Anatomy and Neuroscience
Modelling sensory neuron-epithelial interactions Project Leader Associate Professor Stuart Mazzone Anatomy and Neuroscience
Modulation of intestinal inflammation through nerve stimulation Project Supervisor Dr Martin Stebbing Anatomy and Neuroscience
Molecular mechanisms that contribute to bone marrow pain Head of Laboratory Dr Jason Ivanusic Anatomy and Neuroscience
Montgomery laboratory: Metabolic Tissue Cross-Talk Head of Laboratory Dr Magdalene Montgomery
Physiology
Murray & Xiao laboratory: Neurotrophin and myelin Joint Heads of Laboratory Dr Simon Murray & Dr Junhua Xiao
Anatomy and Neuroscience
Nerve pathways responding to and controlling inflammation in the intestine Project Supervisor Dr Martin Stebbing Anatomy and Neuroscience
Novel drugs and receptors for targeting neural control of digestive system functtion Project Supervisor Dr Rachel McQuade Anatomy and Neuroscience
Novel technique to determine the pKA of clonidine at prejunctional α2-adrenoceptors in sympathetic transmission Project Leader Professor James Angus Pharmacology and Therapeutics
Oxidative stress and neural injury Head of Laboratory Associate Professor Peter Crack Pharmacology and Therapeutics
Pain management using ultrasound-guided local anaesthetic techniques Head of Laboratory Dr Jason Ivanusic Anatomy and Neuroscience
Parker Laboratory: Structural biology and computational drug design Head of Laboratory and Director, Bio21 Institute Professor Michael Parker
Biochemistry and Molecular Biology
Patient voices: An analysis of patients’ information-based priorities and needs Project Leader Associate Professor Megan Munsie Anatomy and Neuroscience
Pebay laboratory: Stem Cell Disease Modelling Head of Laboratory Professor Alice Pebay
Anatomy and Neuroscience Research
Pilbrow laboratory: Physical (biological) anthropology Head of Laboratory Dr Varsha Pilbrow
Anatomy and Neuroscience
Potential of cell therapy to treat Hirschsprung’s disease Head of Laboratory Professor Heather Young
Project Leader Dr Lincon Stamp
Anatomy and Neuroscience
Prognostic biomarker and therapeutic target discovery in stroke Project Leader Dr Jonathon Mangum Pharmacology and Therapeutics
Proliferation of enteric neuron precursors Head of Laboratory Professor Heather Young
Project Leader Professor Heather Young
Anatomy and Neuroscience
Relaxin family peptide hormones Project Leader Associate Professor Tony Hughes Pharmacology and Therapeutics
Risk genes for neuropsychiatric disorders Project Leader Dr Mike Clark Anatomy and Neuroscience
Role of long noncoding RNAs in neurological disorders Project Leader Dr Mike Clark Anatomy and Neuroscience
Rouiller laboratory: Understanding how molecular machines function through cryo-electron microscopy Associate Professor Isabelle Rouiller
Biochemistry and Molecular Biology
Saunders laboratory: Developmental neuroscience and neurotrauma Head of Laboratory Professor Norman Saunders
Pharmacology and Therapeutics
Skeletal morphology Project Leader Dr Varsha Pilbrow Anatomy and Neuroscience
Stroke Head of Laboratory Associate Professor Peter Crack Pharmacology and Therapeutics
Structural Neurobiology Professor Michael Parker Biochemistry and Molecular Biology
The amyloidogenic protease inhibitor Cystatin C in health and disease Prof. Jose Villadangos Biochemistry and Molecular Biology
The Enteric Neural Circuitry Activated During Bacterial-toxin Induced Diarrhoea Research Project Leader Dr Jaime Foong Physiology
The gastrointestinal complications of Parkinson's Disease Project Supervisor Dr Shanti Diwakarla Anatomy and Neuroscience
The GDNF family, peripheral nerve regeneration and pain Project Leader Professor Janet Keast Anatomy and Neuroscience
The heart as a central player in tissue cross-talk Research Project Leader Dr Magdalene Montgomery
Physiology
The influence of neurotrophin signalling upon the generation of myelin Project Leader Dr Simon Murray Anatomy and Neuroscience
The link between cardiovascular disease and neurodegeneration – focus on Alzheimer’s disease Project Leader Associate Professor Christine Wright Pharmacology and Therapeutics
The Role of enteric neurons in gastrointestinal symptoms associated with Autism Spectrum disorders Research Project Leader Dr Elisa Hill-Yardin Physiology
The role of glia in inner retinal changes during retinal degeneration Head of Laboratory Professor Erica Fletcher Anatomy and Neuroscience
The role of glial cells in retinal vascular disease Head of Laboratory Professor Erica Fletcher Anatomy and Neuroscience
The role of microglia in age-related macular degeneration Head of Laboratory Professor Erica Fletcher Anatomy and Neuroscience
The Stemformatics Stem Cell Atlas Project Leader Professor Christine Wells Anatomy and Neuroscience
The taxonomy of enteroendocrine cells and their innervation Project Supervisor Professor John B Furness Anatomy and Neuroscience
The unique features of visceral pain Project Leader Professor Janet Keast Anatomy and Neuroscience
Therapeutic potential of skeletal muscle plasticity and slow muscle programming for muscular dystrophy Research Project Leader Professor Gordon Lynch
Physiology
Tissue communication in non-alcoholic fatty liver disease (NALFD) and liver fibrosis Research Project Leader Dr Magdalene Montgomery
Physiology
Transcriptional profiling of sensory neurons Project Leader Associate Professor Stuart Mazzone Anatomy and Neuroscience
Traumatic brain injury Head of Laboratory Associate Professor Peter Crack Pharmacology and Therapeutics
Understanding how membrane-less organelles form with optogenetic tools A/Prof Danny Hatters Biochemistry and Molecular Biology
Understanding how the ATPase p97 functions at molecular level Associate Professor Isabelle Rouiller Biochemistry and Molecular Biology
Understanding metabolic cross-talk in health and disease - Focus on type 2 diabetes and fatty liver Research Project Leader Dr Magdalene Montgomery
Physiology
Understanding neuro-urothelial communication Project Leader Professor Janet Keast Anatomy and Neuroscience
Understanding the aetiology of hypertension Research Project Leader Professor Andrew Allen
Physiology
Understanding the cellular cues that direct muscle stem cell specification Research Project Leader Professor Gordon Lynch
Physiology
Understanding the molecular basis of myelin repair Project Leader Dr Junhua Xiao Anatomy and Neuroscience
Understanding the role of angiotensin in the rostral ventrolateral medulla Research Project Leader Professor Andrew Allen
Physiology
Unravelling the mysteries of E3 ubiquitin ligase in regulating skeletal muscle size and function Research Project Leader Associate Professor Paul Gregorevic
Physiology
Viral tracing to identify central projections and pathways for sensory neurons that innervate bone Head of Laboratory Dr Jason Ivanusic Anatomy and Neuroscience
Watt laboratory: Metabolism and Diabetes Head of Laboratory Professor Matthew Watt
Physiology
What is the function of Sez6L2 in the forebrain? Head of Laboratory Dr Jenny Gunnersen
Project Leader Dr Kathryn Munro
Anatomy and Neuroscience
Young laboratory: Development of the enteric nervous system Head of Laboratory Professor Heather Young
Anatomy and Neuroscience

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