Cell Signalling

Researching cell signaling pathways and their importance in conveying information among cells to assist in understanding the development of a variety of human diseases.

Groups / Projects Research Lead Dept / Centre
Analysing genetic roles of RNA-binding proteins and alternative splicing in Drosophila stem cells Project Leader Professor Gary Hime Anatomy and Physiology
Assembly of the Commander complex Prof David Stroud
Bedoui laboratory: Innate and adaptive interactions in immunity to infection Head of Laboratory Professor Sammy Bedoui
Microbiology and Immunology
Biogenesis of mitochondrial complexes Prof David Stroud
Cellular trafficking and male fertility Project Leader Professor Gary Hime Anatomy and Physiology
Characterisation of the changes of the endocytic and secretory pathway of dendritic cells upon activation A/Prof Isabelle Rouiller Biochemistry and Pharmacology
Characterising the pathways responsible for ICU-acquired weakness Research Project Leader Dr René Koopman
Anatomy and Physiology
Cutting off the fuel supply to starve cancer: identifying the nutrient dependencies of cancer cells Project Leader Dr Kristin Brown
Biochemistry and Pharmacology
Decoding the trafficking of immune receptors A/Prof Justine Mintern Biochemistry and Pharmacology
Defining new roles for the Hippo signalling pathway in skeletal muscle Research Project Leader Associate Professor Paul Gregorevic
Anatomy and Physiology
Delbridge laboratory: Cardiac phenomics Head of Laboratory Professor Lea Delbridge
Anatomy and Physiology
Designing new optogenetic tools for biomedical research A/Prof Danny Hatters Biochemistry and Pharmacology
Determining the molecular basis of disease-causing mutations in synaptic proteins. Dr Daniel Scott Biochemistry and Pharmacology
Developing a novel class of therapeutics for muscle wasting and frailty Research Project Leader Dr Benjamin Parker
Anatomy and Physiology
Developing innovative animal and cell culture models to study and treat muscular dystrophies Research Project Leader Associate Professor Paul Gregorevic
Anatomy and Physiology
Development of an electromechanical flow-cytometry based cell stimulation system Dr Daniel Scott Biochemistry and Pharmacology
Development of Novel Antimalarial Drugs Prof Leann Tilley
Diabetic cardiomyopathy – an epidemic disease Research Project Leader Professor Lea Delbridge
Anatomy and Physiology
Discovering and characterizing new genes involved in innate immunity, tissue injury and fibrosis Project Leader Professor Christine Wells Anatomy and Physiology
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism Research Project Leader Professor Matthew Watt
Anatomy and Physiology
Engineering G protein-coupled receptors for structural biology and drug discovery with directed evolution. Dr Daniel Scott Biochemistry and Pharmacology
Establishing the effect of glycine/serine metabolism on skeletal muscle cell growth Research Project Leader Dr René Koopman
Anatomy and Physiology
Exercise-induced liver-muscle cross-talk and mitochondrial adaptations Research Project Leader Dr Magdalene Montgomery
Anatomy and Physiology
Exploiting nanoparticles as vaccines A/Prof Justine Mintern Biochemistry and Pharmacology
Exploring new roles for the TGFβ signalling network as a key regulator of skeletal muscle in health and disease Research Project Leader Associate Professor Paul Gregorevic
Anatomy and Physiology
Fragment-based drug discovery using stabilized α1-adrenoceptors Dr Daniel Scott Biochemistry and Pharmacology
Genetics of blood brain barrier formation Project Leader Professor Ben Hogan Anatomy and Physiology
Gregorevic laboratory: Muscle Research and Therapeutics Head of Laboratory Associate Professor Paul Gregorevic
Anatomy and Physiology
Gunnersen laboratory: Neuron development and plasticity Head of Laboratory Associate Professor Jenny Gunnersen
Anatomy and Physiology
Hogan laboratory: Vascular Cell and Developmental Biology Head of Laboratory Professor Ben Hogan
Anatomy and Physiology
How to design a better GPCR drug: understanding the structural basis of ligand selectivity at α1-adrenoceptors. Dr Daniel Scott Biochemistry and Pharmacology
Immune responses to pathogenic bacteria Prof Ian van Driel
Immuno-paralysis following severe infections Prof Jose Villadangos
Improving the formation of protective immunity against human viruses Prof Jose Villadangos
Keast & Osborne laboratory: Neural and Bioelectronic Control of Pelvic Organs Joint Heads of Laboratory Professor Janet Keast & Dr Peregrine Osborne
Anatomy and Physiology
Kristin Brown laboratory Head of Laboratory Dr Kristin Brown
Biochemistry and Pharmacology
Learning from skeletal muscles to develop new treatments for cancer Research Project Leader Associate Professor Paul Gregorevic
Anatomy and Physiology
Live imaging of cellular signalling in vascular development and disease models Project Leader Professor Ben Hogan Anatomy and Physiology
Liz Hinde laboratory Head of Research Group Dr Elizabeth Hinde
Biochemistry and Pharmacology
Mantamadiotis laboratory: Brain Cancer Molecular Biology Dr Theo Mantamadiotis
Microbiology and Immunology
Mechanisms of diastolic heart failure Research Project Leader Professor Lea Delbridge
Anatomy and Physiology
Metabolic reprogramming and chemotherapy resistance in triple-negative breast cancer Project Leader Dr Kristin Brown
Biochemistry and Pharmacology
Michael Parker laboratory Head of Laboratory and Director, Bio21 Institute Professor Michael Parker
Biochemistry and Pharmacology
Mitochondria as targets during bacterial pathogenesis Prof Diana Stojanovski
Molecular mechanisms controlling lymphangiogenesis Project Leader Professor Ben Hogan Anatomy and Physiology
Montgomery laboratory: Metabolic Tissue Cross-Talk Head of Laboratory Dr Magdalene Montgomery
Anatomy and Physiology
MR1 – a molecular alarm system for bacterial infection Prof Jose Villadangos
Multi-omic analysis of exercise induced changes to mitochondria Prof David Stroud
Murray laboratory: Myelin biology Head of Laboratory Associate Professor Simon Murray
Anatomy and Physiology
Novel regulators of germline stem cells Project Leader Professor Gary HIme Anatomy and Physiology
Parker laboratory: Metabolic Proteomics & Signal Transduction Head of Laboratory Dr Benjamin Parker
Anatomy and Physiology
Paul Gleeson laboratory Head of Laboratory Professor Paul Gleeson
Biochemistry and Pharmacology
Peter Crack laboratory Head of Laboratory Associate Professor Peter Crack
Biochemistry and Pharmacology
Role of interferon inducible GTPases in immune defence Prof Ian van Driel
Sex, adiposity and cardiac vulnerability Research Project Leader Professor Lea Delbridge
Anatomy and Physiology
Skeletal muscle signal transduction related to exercise, metabolic disease and human health Research Project Leader Dr Benjamin Parker
Anatomy and Physiology
Smith laboratory: Cardiac Genetics Head of Laboratory Associate Professor Kelly Smith
Anatomy and Physiology
Structural Biology of Cancer Professor Michael Parker Biochemistry and Pharmacology
Structural Neurobiology Professor Michael Parker Biochemistry and Pharmacology
Systems genetics of muscle metabolism Research Project Leader Dr Benjamin Parker
Anatomy and Physiology
The Bonn and Melbourne Research and Graduate School Melbourne Coordinator Dr Marie Greyer
The GDNF family, peripheral nerve regeneration and pain Project Leader Professor Janet Keast Anatomy and Physiology
The heart as a central player in tissue cross-talk Research Project Leader Dr Magdalene Montgomery
Anatomy and Physiology
The immune signature of COVID-19 patients Prof Jose Villadangos
The machines and pathways that facilitate mitochondrial protein import in human cells Dr Diana Stojanovski
The role of protein modifications on muscle development Research Project Leader Dr Benjamin Parker
Anatomy and Physiology
The unique features of visceral pain Project Leader Professor Janet Keast Anatomy and Physiology
Tissue communication in non-alcoholic fatty liver disease (NALFD) and liver fibrosis Research Project Leader Dr Magdalene Montgomery
Anatomy and Physiology
Transcriptional regulation of cancer cell metabolism Project Leader Dr Kristin Brown
Biochemistry and Pharmacology
Transcriptional regulation of intestinal organoid differentiation Project Leader Professor Gary Hime Anatomy and Physiology
Trogocytosis: a novel communication system between cells of the immune system Prof Jose Villadangos
Ultrasonically driven neuromodulation using mechano-responsive proteins Dr Daniel Scott Biochemistry and Pharmacology
Uncovering the interplay between innate immunity and the blood brain barrier in disorders of the CNS Project Leader Professor Christine Wells Anatomy and Physiology
Understanding immune dysfunction in acute myeloid leukemia A/Prof Justine Mintern Biochemistry and Pharmacology
Understanding metabolic cross-talk in health and disease - Focus on type 2 diabetes and fatty liver Research Project Leader Dr Magdalene Montgomery
Anatomy and Physiology
Understanding the interaction between microbiota and T cell immunity Project Leader Professor Sammy Bedoui Microbiology and Immunology
Understanding the structural basis of peptide-activated G protein-coupled receptor signalling to enable drug discovery. Dr Daniel Scott Biochemistry and Pharmacology
Unravelling the mysteries of E3 ubiquitin ligase in regulating skeletal muscle size and function Research Project Leader Associate Professor Paul Gregorevic
Anatomy and Physiology
Using proteomics to diagnose mitochondrial disease Prof David Stroud
Using the immune system to kill tumours A/Prof Justine Mintern Biochemistry and Pharmacology
Watt laboratory: Metabolism and Diabetes Head of Laboratory Professor Matthew Watt
Anatomy and Physiology

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