Role of innate signals in inducing protective T cell immunity

Project Details

Although it is clear that the innate and the adaptive immune system are inextricably linked, precisely how these two arms of the immune system interact still remains unclear. This project examines how specific pathogen sensing pathways contribute to effective killer T cell responses. We are specifically interested in type I interferons and how these are induced and regulated in dendritic cells through molecules or molecule complexes, such as toll-like receptors, STING and inflammasomes.


Research Group

Bedoui laboratory: Innate and adaptive interactions in immunity to infection

Faculty Research Themes

Infection and Immunology

School Research Themes

Molecular Mechanisms of Disease

Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

Microbiology and Immunology

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