Infection & Immunity

Focusing on the mechanisms of infection and immunity and development of new ways to control and treat infectious diseases - from molecular analysis of bacterial and viral infections to the development and function of the immune system.

Groups / Projects Research Lead Dept / Centre
A cell-based model of sporadic prion disease Associate Professor Vicki Lawson Microbiology and Immunology
Age-dependent susceptibility of neurons to RNA virus infection Dr Lukasz Kedzierski Microbiology and Immunology
Antibodies preventing HTLV-1c infection Professor Damian Purcell Microbiology and Immunology
Application of systems genomics to analysing the dynamics of Streptococcus pyogenes infection Dr Mark Davies Microbiology and Immunology
Are there additional MAIT cell antigens? Dr Sidonia Eckle Microbiology and Immunology
Blocking the development of secondary bacterial pneumonia Dr Linda Wakim Microbiology and Immunology
Can resident memory B cells in the lung protect against respiratory syncytial virus? Professor Stephen Kent Microbiology and Immunology
CCVs: Clathrin-coated vesicles and Coxiella containing vacuoles Dr Hayley Newton Microbiology and Immunology
Characterisation of antimicrobial resistance and virulence of novel staphylococcal lineages Associate Professor Steven Tong Microbiology and Immunology
Clinical metagenomics for rapid diagnosis of drug resistant tuberculosis Dr Sarah Dunstan Microbiology and Immunology
Cow antibodies that give the finger to HIV transmission Professor Damian Purcell Microbiology and Immunology
Day Laboratory: Malaria genomics, epidemiology and control Head of Laboratory Professor Karen Day
Microbiology and Immunology
Defining the association between virulence and fitness of seasonal influenza viruses Professor Kanta Subbarao Microbiology and Immunology
Defining the impact of recurrent adaptive mutations on staphylococcal antimicrobial resistance and pathogenesis Professor Ben Howden Microbiology and Immunology
Design and development of antibiotics against multidrug resistant bacteria Project Leader Associate Professor Tony Velkov Biochemistry and Pharmacology
Design of inhibitory drugs for molecular components of the siderophore biosynthetic pathway that are crucial for iron sequestration during mycobacterium tuberculosis (TB) pathogenesis Project Leader Associate Professor Tony Velkov Biochemistry and Pharmacology
Determining the role of diet and microbiota in the progression of lupus Professor Fabienne Mackay Microbiology and Immunology
Development of novel proteomic tools to explore Burkholderia pathogenesis Dr Nichollas Scott Microbiology and Immunology
Diagnosis, treatment and prevention of medically relevant prion diseases Associate Professor Vicki Lawson Microbiology and Immunology
Evolution of streptococcal pathovars Dr Mark Davies Microbiology and Immunology
Evolutionary Genetics of avian influenza A viruses in Australia Dr Michelle Wille Microbiology and Immunology
Gamma delta T cells are important for malaria sporozoite vaccination Dr Lynette Beattie Microbiology and Immunology
Genomic epidemiology and malaria surveillance Project Leader Professor Karen Day Microbiology and Immunology
Harnessing the molecular clock to activate diverse strains of latent HIV Professor Sharon Lewin Microbiology and Immunology
How do tumours impact normal tissue functions? Associate Professor Scott Mueller Microbiology and Immunology
How does ageing affect antibody responses? Project Leader Dr Amy Chung Microbiology and Immunology
How does ageing effect antibody responses? Dr Amy Chung Microbiology and Immunology
How is selective metal ion transport achieved at the host-pathogen interface? Associate Professor Christopher McDevitt Microbiology and Immunology
Ian van Driel laboratory Head of Laboratory Professor Ian van Driel
Biochemistry and Pharmacology
Identification and characterisation of novel malarial transmission-blocking antigens Associate Professor Siddhartha Mahanty Microbiology and Immunology
Identifying novel subsets of immune cells that control cytomegalovirus following transplantation Dr Lucy Sullivan Microbiology and Immunology
Illuminating microbial “dark matter” for antibiotic discovery Dr Sacha Pidot Microbiology and Immunology
Immuno-paralysis following severe infections or trauma Professor Jose Villadangos Microbiology and Immunology
Immunoregulatory functions of the MARCH family of ubiquitin ligases Professor Jose Villadangos Microbiology and Immunology
Impact of Seasonal Malaria Chemoprevention on drug resistance biomarkers and antigenic diversity Professor Karen Day Microbiology and Immunology
Infection induced changes to splenic macrophages Dr Lynette Beattie Microbiology and Immunology
Integrative infectious disease phylodynamics Dr Sebastian Duchene Microbiology and Immunology
Investigating antimalarial drug resistance in response to community interventions in Ghana, West Africa Project Leader Professor Karen Day Microbiology and Immunology
Investigating novel chromatin proteins of the malaria parasite P. falciparum as drug targets. Dr Michael Duffy Microbiology and Immunology
Investigating the diversity of the variant antigen genes of Plasmodium falciparum Project Leader Professor Karen Day Microbiology and Immunology
Investigating the effect of hepatitis B virus splice variants in liver cells and disease progression Professor Peter Revill Microbiology and Immunology
Investigating the role of functional antibodies against Mycobacterium tuberculosis Dr Amy Chung Microbiology and Immunology
Justine Mintern laboratory Head of Laboratory A/Prof Justine Mintern
Biochemistry and Pharmacology
Leann Tilley laboratory Head of Laboratory, Redmond Barry Distinguished Professor of Biochemistry & Pharmacology, ARC Australian Laureate Fellow (2015-2020) Professor Leann Tilley
Biochemistry and Pharmacology
Location, location, location – lodging virus specific T cells in the lung as an approach to protecting against influenza virus infection Dr Linda Wakim Microbiology and Immunology
Malcolm McConville laboratory Head of Laboratory Professor Malcolm McConville
Biochemistry and Pharmacology
Manipulating MAIT cells for increased protection by vaccination and therapy Dr Alexandra Corbett Microbiology and Immunology
Mapping elemental fluxes during host-pathogen interaction Associate Professor Christopher McDevitt Microbiology and Immunology
Metal ion homeostasis in Klebsiella pneumoniae Associate Professor Christopher McDevitt Microbiology and Immunology
Mitochondria and intracellular bacterial pathogens Dr Hayley Newton Microbiology and Immunology
Molecular basis for growth factor surveillance in plasmacytoid dendritic cells Dr Alexander David Barrow Microbiology and Immunology
MR1 – a molecular alarm system for bacterial infection Dr Hamish McWilliam Microbiology and Immunology
Neural regulation of anti-cancer immunity Associate Professor Scott Mueller Microbiology and Immunology
Neurodegeneration in the enteric nervous system Associate Professor Vicki Lawson Microbiology and Immunology
New antibiotics from old bacteria Dr Sacha Pidot Microbiology and Immunology
Novel master-regulators of B-cell biology Professor Fabienne Mackay Microbiology and Immunology
Pathogenesis of HTLV-1 subtype-C infecting remote indigenous Australians Professor Damian Purcell Microbiology and Immunology
Pathogenesis of pneumococcal pneumonia Associate Professor Catherine Satzke Microbiology and Immunology
Pidot Laboratory: Antibiotic Discovery and Biosynthesis Head of Laboratory Dr Sacha Pidot
Microbiology and Immunology
Plasma protein binding of antibiotics Project Leader Associate Professor Tony Velkov Biochemistry and Pharmacology
Population genomics of endemic Streptococcus pyogenes Dr Mark Davies Microbiology and Immunology
Preventing infections of the highly puke-ogenic virus - norovirus Professor Jason Mackenzie Microbiology and Immunology
Programming gamma delta T cells for HIV immunotherapy Professor Stephen Kent Microbiology and Immunology
Protective capacity of malaria-specific liver-tissue-resident memory T cells Dr Lauren Holz Microbiology and Immunology
Quantifying bacterial recombination within globally evolving streptococcal pathogens Dr Mark Davies Microbiology and Immunology
Quorum sensing in malaria Professor Karen Day Microbiology and Immunology
Regeneration of lymphoid tissues Associate Professor Scot Mueller Microbiology and Immunology
RNA control of HIV latency Professor Damian Purcell Microbiology and Immunology
Role of O-linked glycosylation system across the Burkholderia genus Dr Nichollas Scott Microbiology and Immunology
Role of suppressor of cytokine signalling proteins in viral encephalitis Dr Lukasz Kedzierski Microbiology and Immunology
Scott Laboratory: Microbial glycoproteomics and host pathogen interactions Head of Laboratory Dr Nichollas Scott
Microbiology and Immunology
SNAP - Staphylococcus aureus Network Adaptive Platform Trial Associate Professor Steven Tong Microbiology and Immunology
Staphylococcus aureus bloodstream infections in Victorian hospitals: regional differences in disease burden and epidemiology Associate Professor Leon Worth Microbiology and Immunology
Streptococcal transmission and disease Associate Professor Catherine Satzke Microbiology and Immunology
Synergistic and antagonistic interplay between Streptococcus pneumoniae and respiratory viruses Associate Professor Catherine Satzke Microbiology and Immunology
Testing a novel strategy to target chronic lymphocytic leukemia Professor Fabienne Mackay Microbiology and Immunology
The importance of IgA in the protection and control of infectious diseases Project Leader Dr Amy Chung Microbiology and Immunology
The importance of IgA in the protection and control of infectious diseases Dr Amy Chung Microbiology and Immunology
The role of co-pathologies in the clinical presentation of prion disease Associate Professor Vicki Lawson Microbiology and Immunology
The role of glucose metabolism in the regulation of immunity Professor Jose Villadangos Microbiology and Immunology
The role of the prion protein in brain cancer Associate Professor Vicki Lawson Microbiology and Immunology
The space of evolutionary trees in infectious disease epidemiology Dr Sebastian Duchene Microbiology and Immunology
Understanding essential gene regulation in Staphylococcus aureus Professor Tim Stinear Microbiology and Immunology
Understanding the biological chemistry of pneumococcal disease Associate Professor Christopher McDevitt Microbiology and Immunology
Understanding the importance of variation in the capsular polysaccharide of Streptococcus pneumoniae Associate Professor Catherine Satzke Microbiology and Immunology
Understanding the mechanisms that impair anti-tumour adoptive cell therapy Professor Jose Villadangos Microbiology and Immunology
Understanding the role of MAIT cells in immune-mediated pathology Dr Sidonia Eckle Microbiology and Immunology
Understanding the role of MAIT cells in protection from microbial infections Dr Sidonia Eckle Microbiology and Immunology
Unravelling the drivers of scarlet fever pandemics Dr Mark Davies Microbiology and Immunology
Using genomics to investigate the transmission of skin pathogens and antimicrobial resistance in a ‘One Health’ setting Dr Mark Davies Microbiology and Immunology
Using genomics to track transmission of Chlamydia trachomatis Dr Hayley Newton Microbiology and Immunology
Using transcriptional analyses to understand recognition of tumours by natural killer cells Professor Andrew Brooks Microbiology and Immunology
Validating human transgenic mouse models for lupus therapeutics development Professor Fabienne Mackay Microbiology and Immunology
Vertical transmission of Ross River virus in mosquito vectors Dr Julio Rodriguez-Andres Microbiology and Immunology
What do antibodies need to do to protect a woman against pregnancy-malaria? Dr Elizabeth Aitken Microbiology and Immunology
Whole body analysis of human tissue-resident memory T cells Dr Claire Gordon Microbiology and Immunology
Why is the flavivirus RdRp in the nucleus? Professor Jason Mackenzie Microbiology and Immunology

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