Infection & Immunity

Groups / Projects	Research Lead	Dept / Centre
A cell-based model of sporadic prion disease	Associate Professor Vicki Lawson	Microbiology and Immunology
Age-dependent susceptibility of neurons to RNA virus infection	Dr Lukasz Kedzierski	Microbiology and Immunology
Antibodies preventing HTLV-1c infection	Professor Damian Purcell	Microbiology and Immunology
Application of systems genomics to analysing the dynamics of Streptococcus pyogenes infection	Dr Mark Davies	Microbiology and Immunology
Are there additional MAIT cell antigens?	Dr Sidonia Eckle	Microbiology and Immunology
Blocking the development of secondary bacterial pneumonia	Dr Linda Wakim	Microbiology and Immunology
Can resident memory B cells in the lung protect against respiratory syncytial virus?	Professor Stephen Kent	Microbiology and Immunology
CCVs: Clathrin-coated vesicles and Coxiella containing vacuoles	Dr Hayley Newton	Microbiology and Immunology
Characterisation of antimicrobial resistance and virulence of novel staphylococcal lineages	Associate Professor Steven Tong	Microbiology and Immunology
Clinical metagenomics for rapid diagnosis of drug resistant tuberculosis	Dr Sarah Dunstan	Microbiology and Immunology
Coin Laboratory: Genomics and bioinformatics in infectious disease and cancer	Head of Laboratory Professor Lachlan Coin	Microbiology and Immunology
Corbett Laboratory: Mucosal-Associated Invariant T cell detection of microbial metabolites, activation and immune function	Head of Laboratory A/Prof Alexandra Corbett	Microbiology and Immunology
Cow antibodies that give the finger to HIV transmission	Professor Damian Purcell	Microbiology and Immunology
Day Laboratory: Malaria genomics, epidemiology and control	Head of Laboratory Professor Karen Day	Microbiology and Immunology
Defining the association between virulence and fitness of seasonal influenza viruses	Professor Kanta Subbarao	Microbiology and Immunology
Defining the impact of recurrent adaptive mutations on staphylococcal antimicrobial resistance and pathogenesis	Professor Ben Howden	Microbiology and Immunology
Design and development of antibiotics against multidrug resistant bacteria	Project Leader Associate Professor Tony Velkov	Biochemistry and Pharmacology
Design of inhibitory drugs for molecular components of the siderophore biosynthetic pathway that are crucial for iron sequestration during mycobacterium tuberculosis (TB) pathogenesis	Project Leader Associate Professor Tony Velkov	Biochemistry and Pharmacology
Determining the role of diet and microbiota in the progression of lupus	Professor Fabienne Mackay	Microbiology and Immunology
Development of novel proteomic tools to explore Burkholderia pathogenesis	Dr Nichollas Scott	Microbiology and Immunology
Diagnosis, treatment and prevention of medically relevant prion diseases	Associate Professor Vicki Lawson	Microbiology and Immunology
Evolution of streptococcal pathovars	Dr Mark Davies	Microbiology and Immunology
Evolutionary Genetics of avian influenza A viruses in Australia	Dr Michelle Wille	Microbiology and Immunology
Gamma delta T cells are important for malaria sporozoite vaccination	Dr Lynette Beattie	Microbiology and Immunology
Genomic epidemiology and malaria surveillance	Project Leader Professor Karen Day	Microbiology and Immunology
Haque Laboratory	Head of Laboratory Associate Professor Ashraful Haque	Microbiology and Immunology
Harnessing the molecular clock to activate diverse strains of latent HIV	Professor Sharon Lewin	Microbiology and Immunology
How do tumours impact normal tissue functions?	Associate Professor Scott Mueller	Microbiology and Immunology
How does ageing affect antibody responses?	Project Leader Dr Amy Chung	Microbiology and Immunology
How does ageing effect antibody responses?	Dr Amy Chung	Microbiology and Immunology
How is selective metal ion transport achieved at the host-pathogen interface?	Associate Professor Christopher McDevitt	Microbiology and Immunology
Ian van Driel laboratory	Head of Laboratory Professor Ian van Driel	Biochemistry and Pharmacology
Identification and characterisation of novel malarial transmission-blocking antigens	Associate Professor Siddhartha Mahanty	Microbiology and Immunology
Identifying novel subsets of immune cells that control cytomegalovirus following transplantation	Dr Lucy Sullivan	Microbiology and Immunology
Illuminating microbial “dark matter” for antibiotic discovery	Dr Sacha Pidot	Microbiology and Immunology
Immuno-paralysis following severe infections or trauma	Professor Jose Villadangos	Microbiology and Immunology
Immunoregulatory functions of the MARCH family of ubiquitin ligases	Professor Jose Villadangos	Microbiology and Immunology
Impact of Seasonal Malaria Chemoprevention on drug resistance biomarkers and antigenic diversity	Professor Karen Day	Microbiology and Immunology
Infection induced changes to splenic macrophages	Dr Lynette Beattie	Microbiology and Immunology
Integrative infectious disease phylodynamics	Dr Sebastian Duchene	Microbiology and Immunology
Investigating antimalarial drug resistance in response to community interventions in Ghana, West Africa	Project Leader Professor Karen Day	Microbiology and Immunology
Investigating novel chromatin proteins of the malaria parasite P. falciparum as drug targets.	Dr Michael Duffy	Microbiology and Immunology
Investigating the diversity of the variant antigen genes of Plasmodium falciparum	Project Leader Professor Karen Day	Microbiology and Immunology
Investigating the effect of hepatitis B virus splice variants in liver cells and disease progression	Professor Peter Revill	Microbiology and Immunology
Investigating the role of functional antibodies against Mycobacterium tuberculosis	Dr Amy Chung	Microbiology and Immunology
Justine Mintern laboratory	Head of Laboratory A/Prof Justine Mintern	Biochemistry and Pharmacology
Leann Tilley laboratory	Head of Laboratory, Redmond Barry Distinguished Professor of Biochemistry & Pharmacology, ARC Australian Laureate Fellow (2015-2020) Professor Leann Tilley	Biochemistry and Pharmacology
Location, location, location – lodging virus specific T cells in the lung as an approach to protecting against influenza virus infection	Dr Linda Wakim	Microbiology and Immunology
Mackenzie laboratory: Intracellular virus replication and innate immunity	Head of Laboratory Professor Jason Mackenzie	Microbiology and Immunology
Malcolm McConville laboratory	Head of Laboratory Professor Malcolm McConville	Biochemistry and Pharmacology
Manipulating MAIT cells for increased protection by vaccination and therapy	Dr Alexandra Corbett	Microbiology and Immunology
Mapping elemental fluxes during host-pathogen interaction	Associate Professor Christopher McDevitt	Microbiology and Immunology
Metal ion homeostasis in Klebsiella pneumoniae	Associate Professor Christopher McDevitt	Microbiology and Immunology
Mitochondria and intracellular bacterial pathogens	Dr Hayley Newton	Microbiology and Immunology
Molecular basis for growth factor surveillance in plasmacytoid dendritic cells	Dr Alexander David Barrow	Microbiology and Immunology
MR1 – a molecular alarm system for bacterial infection	Dr Hamish McWilliam	Microbiology and Immunology
Neural regulation of anti-cancer immunity	Associate Professor Scott Mueller	Microbiology and Immunology
Neurodegeneration in the enteric nervous system	Associate Professor Vicki Lawson	Microbiology and Immunology
New antibiotics from old bacteria	Dr Sacha Pidot	Microbiology and Immunology
Novel master-regulators of B-cell biology	Professor Fabienne Mackay	Microbiology and Immunology
Pathogenesis of HTLV-1 subtype-C infecting remote indigenous Australians	Professor Damian Purcell	Microbiology and Immunology
Pathogenesis of pneumococcal pneumonia	Associate Professor Catherine Satzke	Microbiology and Immunology
Pidot Laboratory: Antibiotic Discovery and Biosynthesis	Head of Laboratory Dr Sacha Pidot	Microbiology and Immunology
Plasma protein binding of antibiotics	Project Leader Associate Professor Tony Velkov	Biochemistry and Pharmacology
Population genomics of endemic Streptococcus pyogenes	Dr Mark Davies	Microbiology and Immunology
Preventing infections of the highly puke-ogenic virus - norovirus	Professor Jason Mackenzie	Microbiology and Immunology
Programming gamma delta T cells for HIV immunotherapy	Professor Stephen Kent	Microbiology and Immunology
Project 1. How do CD4+ T cells preserve memories during malaria?	Head of Laboratory Associate Professor Ashraful Haque	Microbiology and Immunology
Project 2. CD4+ T cells in acute Graft-versus-Host Disease	Head of Laboratory Associate Professor Ashraful Haque	Microbiology and Immunology
Project 3. Do malaria parasites sense and respond to the host during infection?	Head of Laboratory Associate Professor Ashraful Haque	Microbiology and Immunology
Protective capacity of malaria-specific liver-tissue-resident memory T cells	Dr Lauren Holz	Microbiology and Immunology
Quantifying bacterial recombination within globally evolving streptococcal pathogens	Dr Mark Davies	Microbiology and Immunology
Quorum sensing in malaria	Professor Karen Day	Microbiology and Immunology
Regeneration of lymphoid tissues	Associate Professor Scot Mueller	Microbiology and Immunology
RNA control of HIV latency	Professor Damian Purcell	Microbiology and Immunology
Role of O-linked glycosylation system across the Burkholderia genus	Dr Nichollas Scott	Microbiology and Immunology
Role of suppressor of cytokine signalling proteins in viral encephalitis	Dr Lukasz Kedzierski	Microbiology and Immunology
Scott Laboratory: Microbial glycoproteomics and host pathogen interactions	Head of Laboratory Dr Nichollas Scott	Microbiology and Immunology
SNAP - Staphylococcus aureus Network Adaptive Platform Trial	Associate Professor Steven Tong	Microbiology and Immunology
Staphylococcus aureus bloodstream infections in Victorian hospitals: regional differences in disease burden and epidemiology	Associate Professor Leon Worth	Microbiology and Immunology
Streptococcal transmission and disease	Associate Professor Catherine Satzke	Microbiology and Immunology
Synergistic and antagonistic interplay between Streptococcus pneumoniae and respiratory viruses	Associate Professor Catherine Satzke	Microbiology and Immunology
Testing a novel strategy to target chronic lymphocytic leukemia	Professor Fabienne Mackay	Microbiology and Immunology
The importance of IgA in the protection and control of infectious diseases	Dr Amy Chung	Microbiology and Immunology
The importance of IgA in the protection and control of infectious diseases	Project Leader Dr Amy Chung	Microbiology and Immunology
The role of co-pathologies in the clinical presentation of prion disease	Associate Professor Vicki Lawson	Microbiology and Immunology
The role of glucose metabolism in the regulation of immunity	Professor Jose Villadangos	Microbiology and Immunology
The role of the prion protein in brain cancer	Associate Professor Vicki Lawson	Microbiology and Immunology
The space of evolutionary trees in infectious disease epidemiology	Dr Sebastian Duchene	Microbiology and Immunology
Understanding essential gene regulation in Staphylococcus aureus	Professor Tim Stinear	Microbiology and Immunology
Understanding the biological chemistry of pneumococcal disease	Associate Professor Christopher McDevitt	Microbiology and Immunology
Understanding the importance of variation in the capsular polysaccharide of Streptococcus pneumoniae	Associate Professor Catherine Satzke	Microbiology and Immunology
Understanding the mechanisms that impair anti-tumour adoptive cell therapy	Professor Jose Villadangos	Microbiology and Immunology
Understanding the role of MAIT cells in immune-mediated pathology	Dr Sidonia Eckle	Microbiology and Immunology
Understanding the role of MAIT cells in protection from microbial infections	Dr Sidonia Eckle	Microbiology and Immunology
Unravelling the drivers of scarlet fever pandemics	Dr Mark Davies	Microbiology and Immunology
Using genomics to investigate the transmission of skin pathogens and antimicrobial resistance in a ‘One Health’ setting	Dr Mark Davies	Microbiology and Immunology
Using genomics to track transmission of Chlamydia trachomatis	Dr Hayley Newton	Microbiology and Immunology
Using transcriptional analyses to understand recognition of tumours by natural killer cells	Professor Andrew Brooks	Microbiology and Immunology
Validating human transgenic mouse models for lupus therapeutics development	Professor Fabienne Mackay	Microbiology and Immunology
Vertical transmission of Ross River virus in mosquito vectors	Dr Julio Rodriguez-Andres	Microbiology and Immunology
Villadangos laboratory	Head of Laboratory Professor Jose Villadangos	Biochemistry and Pharmacology
What do antibodies need to do to protect a woman against pregnancy-malaria?	Dr Elizabeth Aitken	Microbiology and Immunology
Whole body analysis of human tissue-resident memory T cells	Dr Claire Gordon	Microbiology and Immunology
Why is the flavivirus RdRp in the nucleus?	Professor Jason Mackenzie	Microbiology and Immunology

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