Project 1. How do CD4+ T cells preserve memories during malaria?
Associate Professor Ashraful Haque
The Haque Group are funded by the Australian NHMRC to discover new molecular mechanisms that govern the transition from effector to memory states in antigen-specific CD4+ T cells. We focus on experimental blood-stage malaria, with the ultimate goal of developing new strategies that boost naturally-acquired immunological memory and vaccine-mediated immunity to this disease. Currently, we apply single-cell transcriptomics and epigenomics technologies, computational modelling, and experimental target validation in vivo to reconstruct the dynamic process of cellular change within CD4+ T cells.
This research project is available to Honours students to join as part of their thesis.
Please contact the Research Group Leader to discuss your options.
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