Development of effector regulatory T cells
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Professor Axel Kallies+61 3 9035 4611
Project Details
After exiting the thymus, Treg cells undergo further differentiation in the periphery. During this process they acquire full suppressive capacity, including IL-10 production, and further diversify into multiple specialised Treg cell types that can enter distinct tissues. Here effector Treg cells exert critical functions such as repressing tissue inflammation, mediating tissue repair and regulating metabolism. This project examines the molecular control of effector Treg cell development, diversification and function.
Research Group
Kallies laboratory: Molecular immunology
Faculty Research Themes
Infection and Immunology, Cancer
School Research Themes
Cancer in Biomedicine, Molecular Mechanisms of Disease
Key Contact
For further information about this research, please contact the research group leader.
Department / Centre
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