Development of effector regulatory T cells

Project Details

After exiting the thymus, Treg cells undergo further differentiation in the periphery. During this process they acquire full suppressive capacity, including IL-10 production, and further diversify into multiple specialised Treg cell types that can enter distinct tissues. Here effector Treg cells exert critical functions such as repressing tissue inflammation, mediating tissue repair and regulating metabolism. This project examines the molecular control of effector Treg cell development, diversification and function.

Research Group

Kallies laboratory: Molecular immunology

Faculty Research Themes

Infection and Immunology, Cancer

School Research Themes

Cancer in Biomedicine, Molecular Mechanisms of Disease

Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

Microbiology and Immunology

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