Project 3. Do malaria parasites sense and respond to the host during infection?
Associate Professor Ashraful Haque
The Haque Group are interested not only in how the host immune response develops during blood-stage malaria, but also how the parasite itself responds to being within the host. We previously found evidence of host-mediated impairment of parasite maturation in experimental in vivo models. Currently, we are testing the hypothesis that parasites sense inhibitory factors released into the bloodstream by the the host, and respond by altering their transcriptional programs, which leads to slowed population growth of parasites within red blood cells.
This research project is available to Honours students to join as part of their thesis.
Please contact the Research Group Leader to discuss your options.
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