Mackenzie laboratory: Intracellular virus replication and innate immunity
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Professor Jason Mackenziejason.mackenzie@unimelb.edu.au
+61 3 9035 8376
Research Overview
We investigate the intracellular replication of Flaviviruses, Noroviruses and now Coronaviruses, to understand how replication influences cellular functions and immune dysfunction. In particular the influences viral replication imparts on metabolic and stress pathways that ultimately lead to immune regulation and dysfunction. Our research has additionally endeavoured to reveal antivirals active against these viruses and the development of vaccine approaches to prevent disease.
Staff
Julio Carrera, Post-doctoral scientist
Alice Trenerry, PhD Student
Joshua Deerain, PhD Student
Nathan Kenney, PhD Student
Caolingzhi Tang, PhD student
Florian Gohr, PhD student (University of Bonn, Germany)
Jessica Ross, MSc Student
Shuoshuo Tian, MSc Student
Katelyn Charry, MSc Student
Collaborators
Prof Peter White, Univeristy of New South Wales
Prof Alex Khromykh, University of Queensland
Dr Jaclyn Pearson, Hudson Institute
Dr Rushika Perera, Colorado State University, USA
Dr Daniel Harari, Weizman Institute, Israel
Research Opportunities
This research project is available to Honours students, Post Doctor Researchers to join as part of their thesis.
Please contact the Research Group Leader to discuss your options.
Research Projects
- Student projects
- Autophagy and Norovirus replication
- Norovirus replication and innate immunity
- Visualization and formation West Nile Virus replication complexes
- West Nile Virus replication and cellular stress responses
- Role of cellular lipids during Flavivirus replication
Faculty Research Themes
School Research Themes
Molecular Mechanisms of Disease, Infection & Immunity
Key Contact
For further information about this research, please contact Head of Laboratory Professor Jason Mackenzie
Department / Centre
Unit / Centre
Mackenzie laboratory: Intracellular virus replication and innate immunity
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