Cancer in Biomedicine

Characterising the molecular mechanisms responsible for cancer progression, predisposition and resistance to treatment.

Groups / Projects Research Lead Dept / Centre
A novel link between metabolism and host defence: O-GlcNAc glycosylation Professor Jose Villadangos Biochemistry and Pharmacology
Adaptive remodelling of metabolism during liver regeneration Project Leader Dr Andrew Cox Biochemistry and Pharmacology
Analysing genetic roles of RNA-binding proteins and alternative splicing in Drosophila stem cells Project Leader Professor Gary Hime Anatomy and Physiology
Analysing protein structures Dr David Ascher Biochemistry and Pharmacology
Andrew Cox laboratory Head of Laboratory Dr Andrew Cox
Biochemistry and Pharmacology
Applications of Nanopore sequencing Project Leader Dr Mike Clark Anatomy and Physiology
Barrow laboratory: Tissue immunosurveillance strategies Head of Laboratory Dr Alexander David Barrow
Microbiology and Immunology
Bo&MeRanG Research Projects Melbourne Coordinator Dr Marie Greyer
Characterising the pathways responsible for ICU-acquired weakness Research Project Leader Dr René Koopman
Anatomy and Physiology
Cheng laboratory: Stem cell and organ size control regulation Head of Laboratory Associate Professor Louise Cheng
Anatomy and Physiology
Clinical Proteomics Project Leader Dr Jonathon Mangum Biochemistry and Pharmacology
Cutting off the fuel supply to starve cancer: identifying the nutrient dependencies of cancer cells Project Leader Dr Kristin Brown
Biochemistry and Pharmacology
David Ascher laboratory Head of Laboratory Dr David Ascher
Biochemistry and Pharmacology
Decoding the trafficking of immune receptors A/Prof Justine Mintern Biochemistry and Pharmacology
Defining new roles for the Hippo signalling pathway in skeletal muscle Research Project Leader Associate Professor Paul Gregorevic
Anatomy and Physiology
Designing better drugs Dr David Ascher Biochemistry and Pharmacology
Designing new optogenetic tools for biomedical research A/Prof Danny Hatters Biochemistry and Pharmacology
Developing innovative animal and cell culture models to study and treat muscular dystrophies Research Project Leader Associate Professor Paul Gregorevic
Anatomy and Physiology
Development of effector regulatory T cells Project Leader Professor Axel Kallies Microbiology and Immunology
Towards understanding new therapies for obesity and diabetes: discovering new regulators of lipid metabolism Research Project Leader Professor Matthew Watt
Anatomy and Physiology
EMT regulators in intestinal and germline stem cells Project Leader Professor Gary Hime Anatomy and Physiology
Establishing the effect of glycine/serine metabolism on skeletal muscle cell growth Research Project Leader Dr René Koopman
Anatomy and Physiology
Exploiting nanoparticles as vaccines A/Prof Justine Mintern Biochemistry and Pharmacology
Exploring new roles for the TGFβ signalling network as a key regulator of skeletal muscle in health and disease Research Project Leader Associate Professor Paul Gregorevic
Anatomy and Physiology
Finding clarity within a blizzard- guiding the solution of cryo-EM structures Dr David Ascher Biochemistry and Pharmacology
Gavin Reid laboratory Head of Laboratory Professor Gavin E. Reid
Biochemistry and Pharmacology
Genetics of blood brain barrier formation Project Leader Professor Ben Hogan Anatomy and Physiology
Gregorevic laboratory: Muscle Research and Therapeutics Head of Laboratory Associate Professor Paul Gregorevic
Anatomy and Physiology
Hime laboratory: Stem cell genetics and Drosophila models of human disease Head of Laboratory Professor Gary Hime
Anatomy and Physiology
Hogan laboratory: Vascular Cell and Developmental Biology Head of Laboratory Professor Ben Hogan
Anatomy and Physiology
How do dietary nutrients affect the ability of stem cells and stem cell-derived tumours to grow and divide? Project Leader A/Professor Louise Cheng Anatomy and Physiology
How do neural stem cells maintain quiescence? Project Leader A/Professor Louise Cheng Anatomy and Physiology
How do neurons maintain their specialised status? Project Leader A/Professor Louise Cheng Anatomy and Physiology
How do tumours compete for resources to grow? Project Leader A/Professor Louise Cheng Anatomy and Physiology
How infection and trauma cause dendritic cell paralysis and lethal immunosuppression Professor Jose Villadangos Microbiology and Immunology
How to harness the immune system to cure cancer: adoptive cell immunotherapy Professor Jose Villadangos Microbiology and Immunology
Immunoregulatory functions of the MARCH family of ubiquitin ligases Professor Jose Villadangos Biochemistry and Pharmacology
Immunosurveillance pathways in brain cancer Project Leader Dr Alexander David Barrow Microbiology and Immunology
Investigating the Dystrophin-Glycoprotein Complex to Protect Muscles from Wasting Conditions Research Project Leader Professor Gordon Lynch
Anatomy and Physiology
Investigating the role of cachexia in the response to surgical tumour resection in mice Research Project Leader Professor Gordon Lynch
Anatomy and Physiology
Isabelle Rouiller laboratory Associate Professor Isabelle Rouiller
Biochemistry and Pharmacology
Kallies laboratory: Molecular immunology Head of Laboratory Professor Axel Kallies
Microbiology and Immunology
Koopman laboratory: Clinical nutrition and muscle metabolism Head of Laboratory Associate Professor René Koopman
Anatomy and Physiology
Kristin Brown laboratory Head of Laboratory Dr Kristin Brown
Biochemistry and Pharmacology
Learning from skeletal muscles to develop new treatments for cancer Research Project Leader Associate Professor Paul Gregorevic
Anatomy and Physiology
Live imaging of cellular signalling in vascular development and disease models Project Leader Professor Ben Hogan Anatomy and Physiology
Liz Hinde laboratory Head of Research Group Dr Elizabeth Hinde
Biochemistry and Pharmacology
Lynch laboratory: Basic and clinical myology Head of Laboratory Professor Gordon Lynch
Anatomy and Physiology
Mangum Lab: Translational Proteomics Head of Laboratory Dr Jonathan Mangum
Biochemistry and Pharmacology
Manipulating immunity to fight infection and tumours A/Prof Justine Mintern Biochemistry and Pharmacology
Mantamadiotis laboratory: Brain Cancer Molecular Biology Dr Theo Mantamadiotis
Microbiology and Immunology
Metabolic reprogramming and chemotherapy resistance in triple-negative breast cancer Project Leader Dr Kristin Brown
Biochemistry and Pharmacology
Metabolic reprogramming of skeletal muscle stem cells Research Project Leader Professor Gordon Lynch Anatomy and Physiology
Michael Parker laboratory Head of Laboratory and Director, Bio21 Institute Professor Michael Parker
Biochemistry and Pharmacology
Molecular basis for growth factor surveillance in natural killer cells Dr Alexander David Barrow Microbiology and Immunology
Molecular basis for growth factor surveillance in natural killer cells Project Leader Dr Alexander David Barrow Microbiology and Immunology
Molecular basis for growth factor surveillance in plasmacytoid dendritic cells Dr Alexander David Barrow Microbiology and Immunology
Molecular basis for growth factor surveillance in plasmacytoid dendritic cells Project Leader Dr Alexander David Barrow Microbiology and Immunology
Molecular mechanisms controlling lymphangiogenesis Project Leader Professor Ben Hogan Anatomy and Physiology
Molecular mechanisms of drug resistance in cancer Project Leader Dr Jonathon Mangum Biochemistry and Pharmacology
MR1 – a molecular alarm system that detects pathogen metabolites Professor Jose Villadangos Microbiology and Immunology
Mueller laboratory: Visualising the immune system in action Head of Laboratory Professor Scott Mueller
Microbiology and Immunology
Novel regulators of germline stem cells Project Leader Professor Gary HIme Anatomy and Physiology
Personalising treatments for genetic diseases Dr David Ascher Biochemistry and Pharmacology
Precursor exhausted T cells in chronic infection and tumors Project Leader Professor Axel Kallies Microbiology and Immunology
Stem Cell Disease Modelling Laboratory Head of Laboratory Professor Alice Pebay
Anatomy and Physiology
Rational Protein Engineering Dr David Ascher Biochemistry and Pharmacology
Resident memory T cells (Trm) Project Leader Professor Axel Kallies Microbiology and Immunology
Restoring immunocompetency in Chronic Lymphocytic Leukemia Senior Research Officer & Lab Manager Catherine Kennedy, PhD Microbiology and Immunology
Sex-specific regulation of adipose tissue immune cells Project Leader Professor Axel Kallies Microbiology and Immunology
Small molecules for BIG targets- Targeting protein-protein interactions with fragments Dr David Ascher Biochemistry and Pharmacology
Structural Biology of Cancer Professor Michael Parker Biochemistry and Pharmacology
Tackling drug resistance Dr David Ascher Biochemistry and Pharmacology
Taylor: Jack Brockhoff Reconstructive Plastic Surgery Research Unit Head of Research Unit Professor Ian Taylor
Anatomy and Physiology
Therapeutic potential of skeletal muscle plasticity and slow muscle programming for muscular dystrophy Research Project Leader Professor Gordon Lynch
Anatomy and Physiology
Transcriptional regulation of cancer cell metabolism Project Leader Dr Kristin Brown
Biochemistry and Pharmacology
Transcriptional regulation of intestinal organoid differentiation Project Leader Professor Gary Hime Anatomy and Physiology
Transcriptional reprogramming of metabolism in liver cancer Project Leader Dr Andrew Cox Biochemistry and Pharmacology
Understanding how the ATPase p97 functions at molecular level Associate Professor Isabelle Rouiller Biochemistry and Pharmacology
Understanding immune dysfunction in acute myeloid leukemia A/Prof Justine Mintern Biochemistry and Pharmacology
Understanding the immune microenvironment in brain tumours Dr Theo Mantamadiotis Microbiology and Immunology
Understanding the Molecular Consequences of Mutations Dr David Ascher David Ascher Biochemistry and Pharmacology
Unravelling the mysteries of E3 ubiquitin ligase in regulating skeletal muscle size and function Research Project Leader Associate Professor Paul Gregorevic
Anatomy and Physiology
Using the immune system to kill tumours A/Prof Justine Mintern Biochemistry and Pharmacology
Using transcriptional analyses to understand recognition of tumours by natural killer cells Professor Andrew Brooks Microbiology and Immunology
Watt laboratory: Metabolism and Diabetes Head of Laboratory Professor Matthew Watt
Anatomy and Physiology

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