Cancer in Biomedicine

Cancer research programs within the School focus on characterising the molecular mechanisms responsible for cancer progression, predisposition and resistance to treatment

Groups / Projects Research Lead Dept / Centre
Analysing and Interpreting protein structures Dr David Ascher Biochemistry and Molecular Biology
Analysing genetic roles of RNA-binding proteins and alternative splicing in Drosophila stem cells Professor Gary Hime Anatomy and Neuroscience
Ascher laboratory: Structural biology and bioinformatics Dr David Ascher
Biochemistry and Molecular Biology
Biochemical and structural basis of the tumour suppression mechanism of CSK-homologous kinase Associate Professor Heung-Chin Cheng Biochemistry and Molecular Biology
Bo&MeRanG Research Projects Dr Marie Greyer
Bogoyevitch laboratory: Regulatory biology Associate Professor Marie Bogoyevitch
Biochemistry and Molecular Biology
Cheng laboratory: Molecular enzymology of protein kinases and phosphatases involved in human diseases Associate Professor Heung-Chin Cheng
Biochemistry and Molecular Biology
Clinical Proteomics Dr Jonathon Mangum Pharmacology and Therapeutics
Comprehensive lipidome profiling to identify functional biomarkers of colorectal cancer metastasis Professor Gavin E. Reid Biochemistry and Molecular Biology
Contribution of proteases to oral cancer pain and metastasis Dr Laura Edgington-Mitchell Biochemistry and Molecular Biology
Designing better drugs Dr David Ascher Biochemistry and Molecular Biology
Development of Novel Chemical Tools to Measure Protease Activation Dr Laura Edgington-Mitchell Biochemistry and Molecular Biology
Development of self-reporting fluorescent chemosensor peptide substrates as molecular sensors Associate Professor Heung-Chin Cheng Biochemistry and Molecular Biology
EMT regulators in intestinal and germline stem cells Professor Gary Hime Anatomy and Neuroscience
Hime laboratory: Stem cell genetics Professor Gary Hime
Anatomy and Neuroscience
Hinde laboratory: Biophysics of Nuclear Organisation Dr Elizabeth Hinde
Biochemistry and Molecular Biology
Imaging transcription factor DNA target search in a living cell Dr Elizabeth Hinde Biochemistry and Molecular Biology
Keeping JNK in its place Associate Professor Marie Bogoyevitch Biochemistry and Molecular Biology
Mangum Lab: Translational Proteomics Dr Jonathan Mangum
Pharmacology and Therapeutics
Mantamadiotis laboratory: Cancer signalling Dr Theo Mantamadiotis
Microbiology and Immunology
Migration of melanoma cells in the neural crest environment Dr Sonja McKeown Anatomy and Neuroscience
Mitochondrial protein biogenesis in mammalian cells Dr Diana Stojanovski Biochemistry and Molecular Biology
Molecular mechanisms of drug resistance in cancer Dr Jonathon Mangum Pharmacology and Therapeutics
Novel interventions to treat cardiac cachexia in cancer and chemotherapy Dr Kate Murphy Physiology
Novel regulators of germline stem cells Professor Gary HIme Anatomy and Neuroscience
Parker Laboratory: Structural biology and computational drug design Professor Michael Parker
Biochemistry and Molecular Biology
Personalising treatments for genetic diseases Dr David Ascher Biochemistry and Molecular Biology
Protein engineering Dr David Ascher Biochemistry and Molecular Biology
Protein kinases involved in pathogenesis of Parkinson’s disease Associate Professor Heung-Chin Cheng Biochemistry and Molecular Biology
Regulation of telomerase activity in B cells Dr Asolina Braun Microbiology and Immunology
Reid laboratory: Proteomics and lipidomics in health and disease Professor Gavin E. Reid
Biochemistry and Molecular Biology
Restoring immunocompetency in Chronic Lymphocytic Leukemia Professor Fabienne Mackay Microbiology and Immunology
Role of chromatin dynamics during the DNA damage response Dr Elizabeth Hinde Biochemistry and Molecular Biology
Structural Biology of Cancer Professor Michael Parker Biochemistry and Molecular Biology
Structural Biology of Infection Professor Michael Parker Biochemistry and Molecular Biology
Structural Neurobiology Professor Michael Parker Biochemistry and Molecular Biology
Taylor: Jack Brockhoff Reconstructive Plastic Surgery Research Unit Professor Ian Taylor
Anatomy and Neuroscience
The gut hormone, ghrelin, its pharmacology, and the possible application of ghrelin receptor agonists in therapy Professor John B Furness Anatomy and Neuroscience
Transcriptional regulation of intestinal organoid differentiation Professor Gary Hime Anatomy and Neuroscience