Project 1. Should we worry about prion associated heart disease?

Project Details

Case reports have described prion associated cardiomyopathy and case control studies support the premise that heart disease is both a cause and consequence of prion disease. These clinical observations are supported by our preliminary observations in mouse models of prion disease. In this study we will establish whether we should worry about prion associated heart disease by modelling the risk of prion disease transmission from prion affected hearts and establishing the relationship between prion infection, enlarged hearts and clinical signs of heart disease.

Researchers

Connor Daymond, Research Project Student
Laura Ellett, PhD Student
Natalia Fortunado de Miranda, PhD Student
Yong Koo, MBiomed
Shana Portelli, PhD Student

Collaborators

Professor David Finkelstein, Florey Department of Neuroscience and Mental Health, The University of Melbourne

Professor John Furness,  Department of Anatomy and Physiology, The University of Melbourne

Dr Julie McAuley,  Department of Microbiology and Immunology, The University of Melbourne

Research Opportunities

This research project is available to PhD students, Masters by Research, Honours students, Master of Biomedical Science, Post Doctor Researchers to join as part of their thesis.
Please contact the Research Group Leader to discuss your options.

Research Group

Lawson laboratory: Transmissible neurodegeneration



Faculty Research Themes

Infection and Immunology, Neuroscience

School Research Themes

Biomedical Neuroscience, Molecular Mechanisms of Disease



Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

Microbiology and Immunology

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