Kallies laboratory: Molecular immunology
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Head of Laboratory
Professor Axel Kallies+61 3 9035 4611
Research Overview
View Professor Kallies' latest PubMed publications listing here.
The Kallies lab studies the molecular control of lymphocyte differentiation in response to antigen. The lab focuses on the roles of transcription factors and cytokines in differentiation, clonal expansion and cellular metabolism of lymphocytes. More recently, the Kallies lab has developed a particular focus on the transcriptional control and cellular metabolism of lymphocytes residing in non-lymphoid tissue, including tumours. The lab develops and applies genetic and molecular approaches, including novel reporter mouse strains, metabolic techniques, transcriptional profiling, chromatin immunoprecipitation (ChIP) and accessible chromatin (ATAC) sequencing.
Staff
Renee Gloury, Research Assistant
Dr Patrick Gubser, Reseach Officer
Dr Kevin Man, Research Officer
Teisha Mason, Research Support Officer
Dr Carlson Tsui, Research Officer
Santiago Valle Torres, PhD Graduate Researcher
Dr Daniel Utzschneider, Research Officer
Sharanya Wijesinghe, PhD Graduate Researcher
Collaborators
Professor Laura Mackay (University of Melbourne)
Professor Thomas Gebhardt (University of Melbourne)
Professor Sammy Bedoui (University of Melbourne)
Dr Wei Shi (The Walter and Eliza Hall Institute)
Professor Stephen Nutt (The Walter and Eliza Hall Institute)
Dr Nick Huntington (The Walter and Eliza Hall Institute)
Professor Mark Febbraio (Monash University)
Professor Michaela Lucas (University of Western Australia)
Professor Tony Tiganis (Peter McCallum Cancer Centre, Melbourne)
Professor Dietmar Zehn (Technical University Munich)
Professor Thomas Korn (Technical University Munich)
Dr Marc Beyer (University of Bonn)
Dr Isis Ludwig-Portugall (University of Bonn)
Funding
2018-2023 NHMRC Research Fellowship. Transcriptional and metabolic regulation of effector and memory lymphocyte differentiation. A Kallies.
2018-2021 NHMRC Project Grant. Molecular pathways that control differentiation and function of tissue-resident memory T cells. A Kallies and L Mackay.
2018-2021 NHMRC A*Star Joint Call for Research. Protective mechanisms of map kinase phosphatase 5 in adipose tissue fibrosis, hepatic steatosis and atherosclerosis. A Kallies and Y Zhang.
Research Opportunities
This research project is available to PhD students, Honours students, Post Doctor Researchers to join as part of their thesis.
Please contact the Research Group Leader to discuss your options.