Cancer in Biomedicine

Cancer research programs within the School focus on characterising the molecular mechanisms responsible for cancer progression, predisposition and resistance to treatment

Groups / Projects Research Lead Dept / Centre
Analysing genetic roles of translational repressors in Drosophila stem cells Associate Professor Gary Hime Anatomy and Neuroscience
Analysing protein structures Dr David Ascher Biochemistry and Molecular Biology
Analysing the role of a novel zinc finger protein in stem cell maintanence Associate Professor Gary Hime Anatomy and Neuroscience
Analysing the role of transcriptional repressors in Drosophila and mouse stem cells Associate Professor Gary Hime Anatomy and Neuroscience
Ascher laboratory: Structural biology and bioinformatics Dr David Ascher
Biochemistry and Molecular Biology
Biochemical and structural basis of the tumour suppression mechanism of CSK-homologous kinase Associate Professor Heung-Chin Cheng Biochemistry and Molecular Biology
Bogoyevitch laboratory: Regulatory biology Associate Professor Marie Bogoyevitch
Biochemistry and Molecular Biology
Buchanan laboratory: Oncogenomics (colorectal cancer) Dr Daniel Buchanan
Pathology
Cancer in Biomedicine
Cell/cell and cell/matrix adhesion in the regulation of tumour-initiating cells Associate Professor Frederic Hollande Pathology
Cheng laboratory: Molecular enzymology of protein kinases and phosphatases involved in human diseases Associate Professor Heung-Chin Cheng
Biochemistry and Molecular Biology
Comprehensive lipidome profiling to identify functional biomarkers of colorectal cancer metastasis Professor Gavin E. Reid Biochemistry and Molecular Biology
Designing better drugs Dr David Ascher Biochemistry and Molecular Biology
Development of self-reporting fluorescent chemosensor peptide substrates as molecular sensors Associate Professor Heung-Chin Cheng Biochemistry and Molecular Biology
Hime laboratory: Stem cell genetics Associate Professor Gary Hime
Anatomy and Neuroscience
Hollande laboratory: Molecular mechanisms of tumour progression Associate Professor Fred Hollande
Pathology
How does regulation of nuclear importation affect stem cell maintenance Associate Professor Gary Hime Anatomy and Neuroscience
Identifying and characterising Lynch syndrome within the population Dr Daniel Buchanan Pathology
Identifying biomarkers of risk and poor prognosis in CRC Dr Daniel Buchanan Pathology
Identifying novel genetic risk factors for colorectal cancer Dr Daniel Buchanan Pathology
Keeping JNK in its place Associate Professor Marie Bogoyevitch Biochemistry and Molecular Biology
Mantamadiotis laboratory: Cancer signalling Dr Theo Mantamadiotis
Pathology
Migration of melanoma cells in the neural crest environment Dr Sonja McKeown Anatomy and Neuroscience
Mitochondrial protein biogenesis in mammalian cells Dr Diana Stojanovski Biochemistry and Molecular Biology
Personalising treatments for genetic diseases Dr David Ascher Biochemistry and Molecular Biology
Pharmacological interventions to attenuate muscle wasting in cancer cachexia Professor Gordon Lynch Physiology
Protein engineering Dr David Ascher Biochemistry and Molecular Biology
Protein kinases involved in pathogenesis of Parkinson’s disease Associate Professor Heung-Chin Cheng Biochemistry and Molecular Biology
Regulators of plasticity and treatment response in colorectal cancer Associate Professor Frederic Hollande Pathology
Reid laboratory: Proteomics and lipidomics in health and disease Professor Gavin E. Reid
Biochemistry and Molecular Biology
Restoring immunocompetency in Chronic Lymphocytic Leukemia Professor Fabienne Mackay Microbiology and Immunology
Southey laboratory: Genetic epidemiology laboratory Professor Melissa Southey
Pathology
Stojanovski laboratory: Mitochondrial biogenesis in health and disease Dr Diana Stojanovski
Biochemistry and Molecular Biology
Taylor: Jack Brockhoff Reconstructive Plastic Surgery Research Unit Professor Ian Taylor
Anatomy and Neuroscience
Understanding the aetiology of Serrated Polyposis Syndrome Dr Daniel Buchanan Pathology