Cancer in Biomedicine

Cancer research programs within the School focus on characterising the molecular mechanisms responsible for cancer progression, predisposition and resistance to treatment

Groups / Projects Research Lead Dept / Centre
Analysing and Interpreting protein structures Dr David Ascher Biochemistry and Molecular Biology
Analysing genetic roles of RNA-binding proteins and alternative splicing in Drosophila stem cells Associate Professor Gary Hime Anatomy and Neuroscience
Ascher laboratory: Structural biology and bioinformatics Dr David Ascher
Biochemistry and Molecular Biology
Biochemical and structural basis of the tumour suppression mechanism of CSK-homologous kinase Associate Professor Heung-Chin Cheng Biochemistry and Molecular Biology
Bo&MeRanG Research Projects Dr Marie Greyer
Bogoyevitch laboratory: Regulatory biology Associate Professor Marie Bogoyevitch
Biochemistry and Molecular Biology
Buchanan laboratory: Oncogenomics (colorectal cancer) Dr Daniel Buchanan
Pathology
Cell/cell and cell/matrix adhesion in the regulation of tumour-initiating cells Associate Professor Frederic Hollande Pathology
Cheng laboratory: Molecular enzymology of protein kinases and phosphatases involved in human diseases Associate Professor Heung-Chin Cheng
Biochemistry and Molecular Biology
Comprehensive lipidome profiling to identify functional biomarkers of colorectal cancer metastasis Professor Gavin E. Reid Biochemistry and Molecular Biology
Designing better drugs Dr David Ascher Biochemistry and Molecular Biology
Development of self-reporting fluorescent chemosensor peptide substrates as molecular sensors Associate Professor Heung-Chin Cheng Biochemistry and Molecular Biology
EMT regulators in intestinal and germline stem cells Associate Professor Gary Hime Anatomy and Neuroscience
Hime laboratory: Stem cell genetics Associate Professor Gary Hime
Anatomy and Neuroscience
Hollande laboratory: Molecular mechanisms of tumour progression Associate Professor Fred Hollande
Pathology
Identifying and characterising Lynch syndrome within the population Dr Daniel Buchanan Pathology
Identifying biomarkers of risk and poor prognosis in CRC Dr Daniel Buchanan Pathology
Identifying novel genetic risk factors for colorectal cancer Dr Daniel Buchanan Pathology
Keeping JNK in its place Associate Professor Marie Bogoyevitch Biochemistry and Molecular Biology
Mantamadiotis laboratory: Cancer signalling Dr Theo Mantamadiotis
Pathology
Migration of melanoma cells in the neural crest environment Dr Sonja McKeown Anatomy and Neuroscience
Mitochondrial protein biogenesis in mammalian cells Dr Diana Stojanovski Biochemistry and Molecular Biology
Novel interventions to treat cardiac cachexia in cancer and chemotherapy Dr Kate Murphy Physiology
Novel regulators of germline stem cells Associate Professor Gary HIme Anatomy and Neuroscience
Parker Laboratory: Structural biology and computational drug design Professor Michael Parker
Biochemistry and Molecular Biology
Personalising treatments for genetic diseases Dr David Ascher Biochemistry and Molecular Biology
Protein engineering Dr David Ascher Biochemistry and Molecular Biology
Protein kinases involved in pathogenesis of Parkinson’s disease Associate Professor Heung-Chin Cheng Biochemistry and Molecular Biology
Regulation of telomerase activity in B cells Dr Asolina Braun Microbiology and Immunology
Regulators of plasticity and treatment response in colorectal cancer Associate Professor Frederic Hollande Pathology
Reid laboratory: Proteomics and lipidomics in health and disease Professor Gavin E. Reid
Biochemistry and Molecular Biology
Restoring immunocompetency in Chronic Lymphocytic Leukemia Professor Fabienne Mackay Microbiology and Immunology
Southey laboratory: Genetic epidemiology laboratory Professor Melissa Southey
Pathology
Structural Biology of Cancer Professor Michael Parker Biochemistry and Molecular Biology
Structural Biology of Infection Professor Michael Parker Biochemistry and Molecular Biology
Structural Neurobiology Professor Michael Parker Biochemistry and Molecular Biology
Taylor: Jack Brockhoff Reconstructive Plastic Surgery Research Unit Professor Ian Taylor
Anatomy and Neuroscience
The gut hormone, ghrelin, its pharmacology, and the possible application of ghrelin receptor agonists in therapy Professor John B Furness Anatomy and Neuroscience
Transcriptional regulation of intestinal organoid differentiation Associate Professor Gary Hime Anatomy and Neuroscience
Understanding the aetiology of Serrated Polyposis Syndrome Dr Daniel Buchanan Pathology