Biomedical Neuroscience

Our research programs in neuroscience, cell and developmental biology, and anatomical sciences aim to understand fundamental biological mechanisms in order to develop new treatments for injury and disease states.

Groups / Projects Research Lead Dept / Centre
A simple method to improve stem cell transplant therapy Dr James Ryall Physiology
Allen laboratory: Central cardiovascular regulation Professor Andrew Allen
Physiology
Alzheimer's disease Professor Roberto Cappai Pathology
Angiotensin and chemoreceptor function Professor Andrew Allen Physiology
Apolipoproteins and amyloid fibril formation in disease Dr Michael Griffin Biochemistry and Molecular Biology
Autologous stem cell therapies in Australia Associate Professor Megan Munsie Anatomy and Neuroscience
Barrett laboratory: Neural plasticity and neurotrophins Associate Professor Graham Barrett
Physiology
Biomedical Neuroscience
Blood Atlas: Understanding cell state and differentiation using genomics data from blood cells Professor Christine Wells Anatomy and Neuroscience
Bornstein laboratory: Enteric neuroscience Professor Joel C Bornstein
Physiology
Brain networks processing respiratory sensations Associate Professor Stuart Mazzone Anatomy and Neuroscience
Brock laboratory: Autonomic and sensory neuroscience A/Professor James Brock
Anatomy and Neuroscience
Can drug-like mimetics of BDNF promote remyelination after injury? Dr Junhua Xiao Anatomy and Neuroscience
Cappai laboratory: Alzheimer's disease, prion disease, Parkinson's disease and Traumatic Brain Injury Professor Roberto Cappai
Pathology
Cell state and cell fate: Systems biology approaches to understanding cell identity Professor Christine Wells Anatomy and Neuroscience
Conformational diversity of G-protein coupled receptors and its importance in activation Associate Professor Paul Gooley Biochemistry and Molecular Biology
Contemplating stem cells in society Dr Claire Tanner Anatomy and Neuroscience
Crack laboratory: Neuropharmacology Associate Professor Peter Crack
Pharmacology and Therapeutics
Crouch laboratory: Neurodegenerative disease Dr Peter Crouch
Pathology
De Iongh laboratory: Ocular development laboratory A/Prof Robb de Iongh
Anatomy and Neuroscience
Dental morphology Dr Varsha Pilbrow Anatomy and Neuroscience
Development of autonomic and nociceptive circuits Professor Janet Keast Anatomy and Neuroscience
Discovery of polyQ ataxin-1 regulation and regulators Associate Professor Marie Bogoyevitch Biochemistry and Molecular Biology
Drugs targeting digestive disorders, discovery and proof of principle Professor John B Furness Anatomy and Neuroscience
Factors that accelerate photoreceptor death: The role of purines Professor Erica Fletcher Anatomy and Neuroscience
Fletcher laboratory: Visual neuroscience Professor Erica Fletcher
Anatomy and Neuroscience
Furness laboratory: Digestive physiology and nutrition Professor John Furness
Anatomy and Neuroscience
Gleeson laboratory: Membrane trafficking and protein sorting in health and disease and development of new therapeutics Professor Paul Gleeson
Biochemistry and Molecular Biology
Glial cells as a source of progenitor cells in degenerative disease Professor Erica Fletcher Anatomy and Neuroscience
Gooley laboratory: Structural biology of disease Associate Professor Paul Gooley
Biochemistry and Molecular Biology
Griffin laboratory: Functional and mis-functional protein-protein interactions Dr Michael Griffin
Biochemistry and Molecular Biology
Growth factors and peptide mimetics Dr Susan Northfield Pharmacology and Therapeutics
Gunnersen laboratory: Neuron development and plasticity Dr Jenny Gunnersen
Anatomy and Neuroscience
Hatters laboratory: Protein misfolding and proteostasis in neurodegenerative diseases Associate Professor Danny Hatters
Biochemistry and Molecular Biology
How BDNF signalling controls myelination? Dr Simon Murray Anatomy and Neuroscience
How does GM-CSF prevent brain damage after traumatic injury? Dr Jenny Gunnersen
Dr Sandy Shultz
Anatomy and Neuroscience
How does inflammation affect the activity of primary afferent neurons that innervate bone? Dr Jason Ivanusic Anatomy and Neuroscience
How does relaxin activate its G-protein coupled receptor? Associate Professor Paul Gooley Biochemistry and Molecular Biology
How sensory signals are detected: Structure function relationships in peripheral sensory nerve terminals Dr Jason Ivanusic Anatomy and Neuroscience
How sensory signals are detected: Structure function relationships in peripheral sensory nerve terminals Associate Professor James Brock Anatomy and Neuroscience
Hoyer laboratory: Translational neuroscience Professor Daniel Hoyer
Pharmacology and Therapeutics
Hughes laboratory: Drug design Associate Professor Tony Hughes
Pharmacology and Therapeutics
Human brain networks processing respiratory sensations Associate Professor Stuart Mazzone Anatomy and Neuroscience
Hypothalamic modulation of basal sympathetic activity Professor Andrew Allen Physiology
Improving bladder health after spinal cord injury Associate Professor James Brock Anatomy and Neuroscience
Improving recovery of injured visceral nerves and their spinal control centres Professor Janet Keast Anatomy and Neuroscience
Innate immunity and neural injury Associate Professor Peter Crack Pharmacology and Therapeutics
Is the “shed” form of Sez-6 proteins responsible for their synapse-promoting effects? Dr Jenny Gunnersen
Dr Kathryn Munro
Anatomy and Neuroscience
Ivanusic laboratory: Pain and sensory mechanisms Dr Jason Ivanusic
Anatomy and Neuroscience
Keast & Osborne laboratory: Neural development, injury and pain Professor Janet Keast & Dr Peregrine Osborne
Anatomy and Neuroscience
Kilpatrick laboratory: Neuroimmunology of Multiple Sclerosis Professor Trevor Kilpatrick
Anatomy and Neuroscience
Lawson laboratory: Neurodegenerative disease caused by prions Associate Professor Vicki Lawson
Pathology
Live cell imaging of neural crest cell migration along the developing gut Professor Heather Young
Professor Heather Young
Anatomy and Neuroscience
Lynch laboratory: Basic and clinical myology Professor Gordon Lynch
Physiology
Mapping the distribution of angiotensin receptors in the brain Professor Andrew Allen Physiology
Mature and developing synaptic transmission between defined classes of enteric neurons Dr Jaime Foong
Physiology
Mazzone laboratory: Respiratory Sensory Neuroscience Associate Professor Stuart Mazzone
Anatomy and Neuroscience Research
Measuring Proteostasis Imbalance in Health and Disease Associate Professor Danny Hatters Biochemistry and Molecular Biology Research
Mechanisms of growth factor signalling Dr Simon Murray Anatomy and Neuroscience
Mechanisms of Toxicity in Huntington's Disease Associate Professor Danny Hatters Biochemistry and Molecular Biology
Modelling sensory neuron-epithelial interactions Associate Professor Stuart Mazzone Anatomy and Neuroscience
Murray & Xiao laboratory: Neurotrophin and myelin Dr Simon Murray & Dr Junhua Xiao
Anatomy and Neuroscience
Novel technique to determine the dissociation constant pKA of clonidine at prejunctional α2-adrenoceptors in sympathetic transmission Professor James Angus Pharmacology and Therapeutics
Ordidge: Melbourne Brain Centre Imaging Unit Professor Roger Ordidge
Anatomy and Neuroscience
Oxidative stress and neural injury Associate Professor Peter Crack Pharmacology and Therapeutics
Parkinson's disease Professor Roberto Cappai Pathology
Patient voices: An analysis of patients’ information-based priorities and needs Associate Professor Megan Munsie Anatomy and Neuroscience
Pilbrow laboratory: Physical (biological) anthropology Dr Varsha Pilbrow
Anatomy and Neuroscience
Potential of cell therapy to treat Hirschsprung’s disease Professor Heather Young
Dr Lincon Stamp
Anatomy and Neuroscience
Probing microtubule organisation Associate Professor Marie Bogoyevitch Biochemistry and Molecular Biology
Proliferation of enteric neuron precursors Professor Heather Young
Professor Heather Young
Anatomy and Neuroscience
Relaxin family peptide hormones Associate Professor Tony Hughes Pharmacology and Therapeutics
Saunders laboratory: Developmental neuroscience and neurotrauma Professor Norman Saunders
Pharmacology and Therapeutics
Signals for endosomal sorting in development and disease Professor Paul Gleeson Biochemistry and Molecular Biology
Skeletal morphology Dr Varsha Pilbrow Anatomy and Neuroscience
Stroke Associate Professor Peter Crack Pharmacology and Therapeutics
The Enteric Neural Circuitry Activated During Bacterial-toxin Induced Diarrhoea Dr Jaime Foong Physiology
The GDNF family, peripheral nerve regeneration and pain Professor Janet Keast Anatomy and Neuroscience
The gut hormone, ghrelin, its pharmacology, and the possible application of ghrelin receptor agonists in therapy Professor John B Furness Anatomy and Neuroscience
The influence of neurotrophin signalling upon the generation of myelin Dr Simon Murray Anatomy and Neuroscience
The link between cardiovascular disease and neurodegeneration – focus on Alzheimer’s disease Associate Professor Christine Wright Pharmacology and Therapeutics
The molecular basis of the propagation of molecular strain types of prions Associate Professor Vicki Lawson Pathology
The Role of enteric neurons in gastrointestinal symptoms associated with Autism Spectrum disorders Dr Elisa Hill-Yardin Physiology
The role of glia in inner retinal changes during retinal degeneration Professor Erica Fletcher Anatomy and Neuroscience
The role of glial cells in retinal vascular disease Professor Erica Fletcher Anatomy and Neuroscience
The role of glycosaminoglycan in the propagation of prions Associate Professor Vicki Lawson Pathology
The role of microglia in age-related macular degeneration Professor Erica Fletcher Anatomy and Neuroscience
The Stemformatics Stem Cell Atlas Rowland Mosbergen Anatomy and Neuroscience
The structure of the IL-11 signalling complex Dr Michael Griffin Biochemistry and Molecular Biology
The unique features of visceral pain Professor Janet Keast Anatomy and Neuroscience
Therapeutic potential of skeletal muscle plasticity and slow muscle programming for muscular dystrophy Professor Gordon Lynch Physiology
Transcriptional profiling of sensory neurons Associate Professor Stuart Mazzone Anatomy and Neuroscience
Traumatic brain injury Associate Professor Peter Crack Pharmacology and Therapeutics
Understanding neuro-urothelial communication Professor Janet Keast Anatomy and Neuroscience
Understanding the aetiology of hypertension Professor Andrew Allen Physiology
Understanding the cellular cues that direct muscle stem cell specification Professor Gordon Lynch Physiology
Understanding the molecular basis of myelin repair Dr Junhua Xiao Anatomy and Neuroscience
Understanding the role of angiotensin in the rostral ventrolateral medulla Professor Andrew Allen Physiology
Vagal nerve stimulation for the treatment of inflammatory bowel disease Professor John B Furness Anatomy and Neuroscience
What is the function of Sez6L2 in the forebrain? Dr Jenny Gunnersen
Dr Kathryn Munro
Anatomy and Neuroscience
Young laboratory: Development of the enteric nervous system Professor Heather Young
Anatomy and Neuroscience