Cell Signalling

Signalling pathways are important in conveying information among cells. These pathways play an important role in the process of normal development and study of their deregulation assists in our understanding of the development of a variety of human diseases.

Groups / Projects Research Lead Dept / Centre
A new function of the cytokine BAFF in dendritic cell maturation: Implications for immunity and cancers Professor Fabienne Mackay | Dr Beatriz Garcillan Microbiology and Immunology
Analysing genetic roles of RNA-binding proteins and alternative splicing in Drosophila stem cells Associate Professor Gary Hime Anatomy and Neuroscience
Biochemical and structural basis of the tumour suppression mechanism of CSK-homologous kinase Associate Professor Heung-Chin Cheng Biochemistry and Molecular Biology
Bogoyevitch laboratory: Regulatory biology Associate Professor Marie Bogoyevitch
Biochemistry and Molecular Biology
Brock laboratory: Autonomic and sensory neuroscience A/Professor James Brock
Anatomy and Neuroscience
Can drug-like mimetics of BDNF promote remyelination after injury? Dr Junhua Xiao Anatomy and Neuroscience
Cell biology of membrane receptors regulating the serum half-life of therapeutic proteins Professor Paul Gleeson Biochemistry and Molecular Biology
Cell Signalling
Cellular trafficking and male fertility Associate Professor Gary Hime Anatomy and Neuroscience
Cheng laboratory: Molecular enzymology of protein kinases and phosphatases involved in human diseases Associate Professor Heung-Chin Cheng
Biochemistry and Molecular Biology
Defining molecular machinery and cargo sorting along Golgi transport pathways Professor Paul Gleeson Biochemistry and Molecular Biology
Delbridge laboratory: Cardiac phenomics Professor Lea Delbridge
Physiology
Development of self-reporting fluorescent chemosensor peptide substrates as molecular sensors Associate Professor Heung-Chin Cheng Biochemistry and Molecular Biology
Diabetic cardiomyopathy – an epidemic disease Professor Lea Delbridge Physiology
Discovering and characterizing new genes involved in innate immunity, tissue injury and fibrosis Professor Christine Wells Anatomy and Neuroscience
Elucidating the beneficial and harmful elements of the BAFF/APRIL system in multiple sclerosis Professor Fabienne Mackay | Dr Beatriz Garcillan Microbiology and Immunology
EMT regulators in intestinal and germline stem cells Associate Professor Gary Hime Anatomy and Neuroscience
Gleeson laboratory: Membrane trafficking and protein sorting in health and disease and development of new therapeutics Professor Paul Gleeson
Biochemistry and Molecular Biology
Gunnersen laboratory: Neuron development and plasticity Dr Jenny Gunnersen
Anatomy and Neuroscience
Hime laboratory: Stem cell genetics Associate Professor Gary Hime
Anatomy and Neuroscience
Hollande laboratory: Molecular mechanisms of tumour progression Associate Professor Fred Hollande
Pathology
How BDNF signalling controls myelination? Dr Simon Murray Anatomy and Neuroscience
How sensory signals are detected: Structure function relationships in peripheral sensory nerve terminals Associate Professor James Brock Anatomy and Neuroscience
Hubbard & Mangum laboratory: Proteomics and calcium biology Professor Mike Hubbard
Pharmacology and Therapeutics
Improving bladder health after spinal cord injury Associate Professor James Brock Anatomy and Neuroscience
Keast & Osborne laboratory: Neural development, injury and pain Professor Janet Keast & Dr Peregrine Osborne
Anatomy and Neuroscience
Keeping JNK in its place Associate Professor Marie Bogoyevitch Biochemistry and Molecular Biology
Mantamadiotis laboratory: Cancer signalling Dr Theo Mantamadiotis
Pathology
Mechanisms of growth factor signalling Dr Simon Murray Anatomy and Neuroscience
Murray & Xiao laboratory: Neurotrophin and myelin Dr Simon Murray & Dr Junhua Xiao
Anatomy and Neuroscience
Novel regulators of germline stem cells Associate Professor Gary HIme Anatomy and Neuroscience
Protein kinases involved in pathogenesis of Parkinson’s disease Associate Professor Heung-Chin Cheng Biochemistry and Molecular Biology
Regulation of telomerase activity in B cells Dr Asolina Braun Microbiology and Immunology
Regulators of plasticity and treatment response in colorectal cancer Associate Professor Frederic Hollande Pathology
Signals for endosomal sorting in development and disease Professor Paul Gleeson Biochemistry and Molecular Biology
Steroid hormones and heart failure – sex perspectives Professor Lea Delbridge Physiology
The GDNF family, peripheral nerve regeneration and pain Professor Janet Keast Anatomy and Neuroscience
The influence of neurotrophin signalling upon the generation of myelin Dr Simon Murray Anatomy and Neuroscience
The Role of CXCR7 in Tissue Fibrosis Dr Asolina Braun Microbiology and Immunology
The role of Hedgehog signalling during ocular morphogenesis A/Prof Robb de Iongh
Anatomy and Neuroscience
The unique features of visceral pain Professor Janet Keast Anatomy and Neuroscience
Transcriptional regulation of intestinal organoid differentiation Associate Professor Gary Hime Anatomy and Neuroscience
Uncovering the interplay between innate immunity and the blood brain barrier in disorders of the CNS Professor Christine Wells Anatomy and Neuroscience
Understanding the molecular basis of myelin repair Dr Junhua Xiao Anatomy and Neuroscience