Cellular Imaging & Structural Biology

There is considerable expertise in cellular imaging and structural biology in the School which is applied to a wide range of biomedical research programs. Platforms include fluorescence, live imaging, 2-photon imaging, transmission and scanning electron microscopy as well as whole body imaging and imaging mass spectroscopy.

Groups / Projects Research Lead Dept / Centre
Adverse maternal environment in females born small and transgenerational consequences Professor Mary Wlodek Physiology
Analysing and Interpreting protein structures Dr David Ascher Biochemistry and Molecular Biology
Being born small programs growth restriction, deficits and disease in the next generation Professor Mary Wlodek Physiology
Bo&MeRanG Research Projects Dr Marie Greyer
Brock laboratory: Autonomic and sensory neuroscience A/Professor James Brock
Anatomy and Neuroscience
Can drug-like mimetics of BDNF promote remyelination after injury? Dr Junhua Xiao Anatomy and Neuroscience
Cellular Imaging & Structural Biology
Conformational diversity of G-protein coupled receptors and its importance in activation Associate Professor Paul Gooley Biochemistry and Molecular Biology
Defining molecular machinery and cargo sorting along Golgi transport pathways Professor Paul Gleeson Biochemistry and Molecular Biology
Dendritic cell maturation following different microbial stimulation Professor William (Bill) Heath Microbiology and Immunology
Dental morphology Dr Varsha Pilbrow Anatomy and Neuroscience
Designing better drugs Dr David Ascher Biochemistry and Molecular Biology
Discovery of polyQ ataxin-1 regulation and regulators Associate Professor Marie Bogoyevitch Biochemistry and Molecular Biology
Early life exercise reprograms pancreatic and heart deficits in offspring born small Professor Mary Wlodek Physiology
Factors that accelerate photoreceptor death: The role of purines Professor Erica Fletcher Anatomy and Neuroscience
Fletcher laboratory: Visual neuroscience Professor Erica Fletcher
Anatomy and Neuroscience
Gleeson laboratory: Membrane trafficking and protein sorting in health and disease and development of new therapeutics Professor Paul Gleeson
Biochemistry and Molecular Biology
Glial cells as a source of progenitor cells in degenerative disease Professor Erica Fletcher Anatomy and Neuroscience
Gooley laboratory: Structural biology of disease Associate Professor Paul Gooley
Biochemistry and Molecular Biology
Gunnersen laboratory: Neuron development and plasticity Dr Jenny Gunnersen
Anatomy and Neuroscience
Hatters laboratory: Protein misfolding and proteostasis in neurodegenerative diseases Associate Professor Danny Hatters
Biochemistry and Molecular Biology
Heath laboratory: CD8 T lymphocytes, dendritic cells, self tolerance and immunity Professor William (Bill) Heath
Microbiology and Immunology
How BDNF signalling controls myelination? Dr Simon Murray Anatomy and Neuroscience
How does relaxin activate its G-protein coupled receptor? Associate Professor Paul Gooley Biochemistry and Molecular Biology
How sensory signals are detected: Structure function relationships in peripheral sensory nerve terminals Associate Professor James Brock Anatomy and Neuroscience
Imaging effector and memory T cell responses in the skin following Herpes Simplex Virus-1 infection Professor William (Bill) Heath Microbiology and Immunology
Imaging the priming of CD8 Killer T cell responses to Herpes Simplex Virus-1 skin infection Professor William (Bill) Heath Microbiology and Immunology
Improved vaccines by targeting to dendritic cells Professor William (Bill) Heath Microbiology and Immunology
Improving bladder health after spinal cord injury Associate Professor James Brock Anatomy and Neuroscience
Intraepithelial T cells in anti-viral immunity Professor Francis (Frank) Carbone Microbiology and Immunology
Intravital imaging of T cell responses in the brain during cerebral malaria infection Professor William (Bill) Heath Microbiology and Immunology
Keast & Osborne laboratory: Neural development, injury and pain Professor Janet Keast & Dr Peregrine Osborne
Anatomy and Neuroscience
Keeping JNK in its place Associate Professor Marie Bogoyevitch Biochemistry and Molecular Biology
Live cell imaging of neural crest cell migration along the developing gut Professor Heather Young
Professor Heather Young
Anatomy and Neuroscience
Lymphoid stromal cell responses to infection Associate Professor Scott Mueller Microbiology and Immunology
Malaria and Tissue Resident Memory T cells (TRM) in the liver Professor William (Bill) Heath Microbiology and Immunology
Measuring Proteostasis Imbalance in Health and Disease Associate Professor Danny Hatters Biochemistry and Molecular Biology Research
Mechanisms of growth factor signalling Dr Simon Murray Anatomy and Neuroscience
Mechanisms of Toxicity in Huntington's Disease Associate Professor Danny Hatters Biochemistry and Molecular Biology
Migration of melanoma cells in the neural crest environment Dr Sonja McKeown Anatomy and Neuroscience
Mueller laboratory: Adaptive immune responses to infection, lymphoid stromal cells, and imaging the immune system Associate Professor Scott Mueller
Microbiology and Immunology
Murray & Xiao laboratory: Neurotrophin and myelin Dr Simon Murray & Dr Junhua Xiao
Anatomy and Neuroscience
Nervous regulation of T cell migration and anti-viral Immunity Associate Professor Scott Mueller Microbiology and Immunology
Pilbrow laboratory: Physical (biological) anthropology Dr Varsha Pilbrow
Anatomy and Neuroscience
Priming of T cell responses to viral infection Associate Professor Scott Mueller Microbiology and Immunology
Probing microtubule organisation Associate Professor Marie Bogoyevitch Biochemistry and Molecular Biology
Protein engineering Dr David Ascher Biochemistry and Molecular Biology
Protein trafficking and cellular architecture Professor Leann Tilley Biochemistry and Molecular Biology
Self-tolerance: Interactions between thymic stroma and dendritic cells Professor William (Bill) Heath Microbiology and Immunology
Skeletal morphology Dr Varsha Pilbrow Anatomy and Neuroscience
Stojanovski laboratory: Mitochondrial biogenesis in health and disease Dr Diana Stojanovski
Biochemistry and Molecular Biology
T cell responses in the brain during experimental cerebral malaria infection Associate Professor Scott Mueller Microbiology and Immunology
Taylor: Jack Brockhoff Reconstructive Plastic Surgery Research Unit Professor Ian Taylor
Anatomy and Neuroscience
The influence of neurotrophin signalling upon the generation of myelin Dr Simon Murray Anatomy and Neuroscience
The role of glia in inner retinal changes during retinal degeneration Professor Erica Fletcher Anatomy and Neuroscience
The role of glial cells in retinal vascular disease Professor Erica Fletcher Anatomy and Neuroscience
The role of microglia in age-related macular degeneration Professor Erica Fletcher Anatomy and Neuroscience
The role of the rabies P protein in host cell evasion and viral replication Associate Professor Paul Gooley Biochemistry and Molecular Biology
Tilley laboratory: Measuring and modelling malaria parasites to develop new antimalarials Professor Leann Tilley
Biochemistry and Molecular Biology
Tissue-resident memory T cells in the skin Associate Professor Scott Mueller Microbiology and Immunology
Understanding neuro-urothelial communication Professor Janet Keast Anatomy and Neuroscience
Understanding the molecular basis of myelin repair Dr Junhua Xiao Anatomy and Neuroscience
Using biochemical approaches to investigating the trafficking and mechanism of action of the antiviral molecule, IFITM3 Dr Linda Wakim Microbiology and Immunology
Vaccination against liver-stage Plasmodium for malaria prevention Professor William (Bill) Heath Microbiology and Immunology