Malaria epidemiology and elimination in high transmission settings in West Africa

Project Details

Despite significant headway in reducing the global burden of malaria since the Roll Back Malaria initiative was launched in 1998, recent data from the World Health Organization (WHO) shows that global progress towards eradication has stalled. The risk of Plasmodium falciparum rebound is greater for sub-Saharan Africa where the majority of malaria infections are chronic and asymptomatic, therefore going untreated and creating a persistent reservoir to fuel transmission. The large size of this reservoir is one of the greatest challenges to malaria elimination at a local and regional level. We have been investigating the diversity of P. falciparum in this reservoir to better understand the resilience of the parasite population to malaria control interventions in Bongo District located in the Upper East Region of Ghana, West Africa. This project has been undertaken through a long-standing collaboration with Prof. Koram (Noguchi Memorial Institute for Medical Research, Accra, Ghana) and Dr. Oduro (Navrongo Health Research Centre, Navrongo, Ghana).

Research Group

Day Laboratory: Malaria genomics, epidemiology and control

Faculty Research Themes

Infection and Immunology

School Research Themes

Infection & Immunity

Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

Microbiology and Immunology

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