Cardio-Respiratory

Research in the School is focussed on the impact of diseases having an adverse impact on cardio-respiratory function.

Groups / Projects	Research Lead	Dept / Centre
Allen laboratory: Central cardiovascular regulation	Head of Laboratory Professor Andrew Allen	Physiology
Brain networks processing respiratory sensations	Project Leader Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Delbridge laboratory: Cardiac phenomics	Head of Laboratory Professor Lea Delbridge	Physiology
Effects of hypertension on renal and hindquarter vascular reactivity in vivo and in vitro	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
Endothelin pharmacology in the setting of pulmonary hypertension	Project Leader Professor James Angus	Pharmacology and Therapeutics
Functional genomic screens for cardiovascular drug discovery	Research Project Leader Dr Enzo Porrello	Physiology
Human brain networks processing respiratory sensations	Project Leader Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Improving the diagnostic outcomes of patients with mitochondrial disease	Dr David Stroud	Biochemistry and Molecular Biology
Lung Disease Research Laboratory	Head of Laboratory Professor Gary P Anderson	Pharmacology and Therapeutics
Manipulating the endocannabinoid system to alter cardiovascular function in hypertension	Dr Makhala Khammy	Pharmacology and Therapeutics
Mazzone laboratory: Respiratory Sensory Neuroscience	Head of Research Group Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Modeling human heart development using human cardiac organoids	Research Project Leader Dr Enzo Porrello	Physiology
Modelling sensory neuron-epithelial interactions	Project Leader Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Montgomery laboratory: Metabolic Tissue Cross-Talk	Head of Laboratory Dr Magdalene Montgomery	Physiology
Novel technique to determine the pKA of clonidine at prejunctional α2-adrenoceptors in sympathetic transmission	Project Leader Professor James Angus	Pharmacology and Therapeutics
Pathogenesis of chronic lung disease	Head of Laboratory Dr Michelle Hansen	Pharmacology and Therapeutics
Porrello laboratory: Cardiac Regeneration	Head of Laboratory Enzo Porrello	Physiology
Post-natal control of cardiac gene regulatory networks	Research Project Leader Dr Enzo Porrello	Physiology
Preclinical pharmacology – cardiovascular efficacy and safety R&D	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
Reassessment of α1-adrenoceptor mechanism in artery contraction: role of ATP and pannexin channels	Project Leader Professor James Angus	Pharmacology and Therapeutics
Smith laboratory: Cardiac Form and Function	Head of Laboratory Associate Professor Kelly Smith	Physiology
Stroud laboratory: Mitochondrial Systems Biology	Head of Research Group Dr David Stroud	Biochemistry and Molecular Biology
The amyloidogenic protease inhibitor Cystatin C in health and disease	Prof. Jose Villadangos	Biochemistry and Molecular Biology
The cardiovascular pharmacology of snake venoms from Papua New Guinea and Australia	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
The innate immune system in the respiratory tract	Project Leader Professor David Jackson	Microbiology and Immunology
The link between cardiovascular disease and neurodegeneration – focus on Alzheimer’s disease	Project Leader Associate Professor Christine Wright	Pharmacology and Therapeutics
Transcriptional profiling of sensory neurons	Project Leader Associate Professor Stuart Mazzone	Anatomy and Neuroscience
Trovafloxacin – an antibiotic with additional properties	Project Leader Professor James Angus	Pharmacology and Therapeutics
Understanding the assembly of mitochondrial machines	Dr David Stroud	Biochemistry and Molecular Biology
Wlodek laboratory: Fetal, postnatal & adult physiology & disease laboratory	Head of Laboratory Professor Mary Wlodek	Physiology
Wright laboratory: Cardiovascular Therapeutics Unit	Head of Laboratory Associate Professor Christine E Wright	Pharmacology and Therapeutics