Meet Sarah Londrigan
Dr Sarah Londrigan completed her Bachelor of Science (Honours) and PhD research at the University of Melbourne in 2002, where she identified novel cell surface receptors for rotavirus entry during infection of host cells. Her postdoctoral research from 2002 to 2008 at the Walter and Eliza Hall Institute (WEHI) involved creating immunomodulatory adenoviruses that generated local immunosuppression during islet transplantation to treat Type I diabetes. Since then, Sarah's research has focused on pathways that influenza, and other respiratory viruses, use to infect host cells. Specifically, Dr Londrigan is investigating how airway immune cells control viral replication to prevent severe infection. Her current projects include investigating why particular respiratory viruses are highly pathogenic, leading to very severe disease.
After re-joining the Department in 2008, teaming up with Professors Andrew Brooks and Patrick Reading, I have expanded my research interests in virus-host interactions, focusing on influenza virus. My group’s research program is working to understand the role of innate immunity in controlling influenza and other respiratory viruses including SARS-CoV-2. In particular, we study macrophages and their ability to restrict virus infection.