Alastair Stewart presents platform technology at MPS World Summit in New Orleans

Symposium lecture and roundtable outline the method developed in the Stewart Lab at the ARC Centre for Personalised Therapeutics Technologies, Department of Biochemistry and Pharmacology.

Micro-physiological systems (MPS) cover bioengineering breakthroughs that reproduce organ architecture and function in vitro. The inaugural MPS World Summit aimed to accelerate scientific developments, their implementation and global harmonisation in the MPS field.

In the research poster and related presentation, Prof Stewart and Dr Xumei Gao, Research Fellow and 2022 Trajan REDI-Fellow (Department of Biochemistry and Pharmacology), focused on circadian cell physiology and the representation of cells in conventional cell culture.

Due to limitations and distortion of circadian biology in preclinical models, the team designed, built and validated a platform technology for entraining circadian rhythm in cell culture and MPS systems.

Dr Bryan Gao, ARC Centre for Personalised Therapeutics Technologies (ARC-CPTT) postdoctoral fellow and now REDI-Fellow, and Prof Alastair Stewart have also recently published on a multiplexed microfluidic pump that enables many biomedical research applications, including the use of plasma-like culture media and entrainment of circadian rhythm in cell culture. The research is supported by the ARC-CPTT and Trajan Scientific and Medical.

Professor Stewart has also been recently elected to the Inaugural Board of the International Microphysiological Systems Society (IMPSS).

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