Equipment & Services
Equipment List [select section to view]
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Comprehensive metabolic phenotyping equipment
Metabolic cage system
Promethion 16 cage system, Sable, Nevada, USA
- Simultaneously measures physical activity (with or without wheel), food/water intake and indirect gas exchange calorimetry. Non-invasive recording of O² consumption and CO² production in individual mice allows calculation of the respiratory exchange ratio (RER) and energy expenditure.
Indirect calorimetry was used to measure and compare metabolic parameters in two groups of male, age-matched C57BL/6 mice over a 24-hr period, with one group receiving treatment injection and the control group receiving a vehicle. The graphs above show data for oxygen consumption (A and B), carbon dioxide production (C and D), respiratory quotient (E and F), energy expenditure (G and H), food intake (I and J), and ambulatory activity (K). Results are shown as mean ± SEM.
Minispec MRI scanner
LF50H Minispec, Bruker, Germany
- Fat and lean mass measured non-invasively in awake mice using time delay nuclear magnetic resonance (TD-NMR) spectroscopy
Body composition for lean and fat mass was measured in age-matched male mice fed either a chow or high-fat diet. Results are shown as mean ± SEM.
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Functional testing equipment
Anaesthesia delivery system
SomnoSuite vapouriser, Kent Scientific, Connecticut, USA
- Uses room air to deliver isoflurane at a low flow rate in proportion to the animal's size
Electrocardiogram (ECG) recorder
ECGenie, Massachusetts, USA
- Heart electrical function in conscious mice
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Heart function was assessed in aged-matched male mice in either a sedentary control group or a trained group, measuring for changing in heart rate (beats per minute) and heart rate variation (beats per minutes). Results are shown as mean ± SEM.
Glucose monitors (hand-held)
Accu chek glucometer, Roche, Basel, Switzerland
- Glucose and insulin tolerance tests
Laser Doppler
MoorLDI, Devon, UK
- Hind limb circulation including quantification of blood flow during restriction and recovery
Oxygen bomb calorimeter
CAL3K-U, DDS Calorimeters, Gauteng, South Africa
- Caloric content of specialty diets and faecal samples
Bomb calorimetry was used to assess faecal energy and digestive efficiency in age-matched male mice in either a control group or drug treatment group. Results are shown as mean ± SEM.
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Muscle and exercise studies equipment
Acceleration/velocity race track
Acceleration/Velocity Race Track, Columbus Instruments, Ohio, USA
- 2.5 m enclosed track with 24 photobeam “curtains” to assess speed
Gait analysis instrumentation
DigiGait, Mouse Specifics, Massachusetts, USA
- Performs gait analysis using ventral plane videography
Grip strength meter
GT3 Grip Strength Test, Bioseb, Vitrolles, France
- Foreleg muscular strength
Rota-rod motor coordination
LE8205 Accelerating Rotarod, PanLab, Harvard Apparatus, USA
- To measure motor coordination, balance and fatigue
Spontaneous running wheel
0297-16, Columbus Instruments, Ohio, USA
- 16 home cages with wheels and tracking software for exercise vs. sedentary studies
Treadmill
Exer 3/6 treadmill with incline, Columbus Instruments, Ohio, USA
- Exercise training with 6 lanes, adjustable speed and optional incline
Pricing
View pricing schedule
Bookings
For equipment bookings please contact the MMMPP Coordinator.