Equipment List [select section to view]

• Comprehensive metabolic phenotyping equipment

  Metabolic cage system

  

  Promethion 16 cage system, Sable, Nevada, USA

  • Simultaneously measures physical activity (with or without wheel), food/water intake and indirect gas exchange calorimetry. Non-invasive recording of O_² consumption and CO_² production in individual mice allows calculation of the respiratory exchange ratio (RER) and energy expenditure.

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  Minispec MRI scanner

  

  LF50H Minispec, Bruker, Germany

  • Fat and lean mass measured non-invasively in awake mice using time delay nuclear magnetic resonance (TD-NMR) spectroscopy
• Functional testing equipment

  Anaesthesia delivery system

  

  SomnoSuite vapouriser, Kent Scientific, Connecticut, USA

  • Uses room air to deliver isoflurane at a low flow rate in proportion to the animal's size

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  Electrocardiogram (ECG) recorder

  

  ECGenie, Massachusetts, USA

  • Heart electrical function in conscious mice

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  Glucose monitors (hand-held)

  

  Accu chek glucometer, Roche, Basel, Switzerland

  • Glucose and insulin tolerance tests

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  Laser Doppler

  

  MoorLDI, Devon, UK

  • Hind limb circulation including quantification of blood flow during restriction and recovery

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  Oxygen bomb calorimeter

  

  CAL3K-U, DDS Calorimeters, Gauteng, South Africa

  • Caloric content of specialty diets and faecal samples
• Muscle and exercise studies equipment

  Acceleration/velocity race track

  

  Acceleration/Velocity Race Track, Columbus Instruments, Ohio, USA

  • 2.5 m enclosed track with 24 photobeam “curtains” to assess speed

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  Gait analysis instrumentation

  

  DigiGait, Mouse Specifics, Massachusetts, USA

  • Performs gait analysis using ventral plane videography

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  Grip strength meter

  

  GT3 Grip Strength Test, Bioseb, Vitrolles, France

  • Foreleg muscular strength

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  Rota-rod motor coordination

  

  LE8205 Accelerating Rotarod, PanLab, Harvard Apparatus, USA

  • To measure motor coordination, balance and fatigue

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  Spontaneous running wheel

  

  0297-16, Columbus Instruments, Ohio, USA

  • 16 home cages with wheels and tracking software for exercise vs. sedentary studies

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  Treadmill

  

  Exer 3/6 treadmill with incline, Columbus Instruments, Ohio, USA

  • Exercise training with 6 lanes, adjustable speed and optional incline

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