Dodd laboratory: Metabolic Neuroscience

Research Overview

View Dr Dodd's latest PubMed publications listing here

Metabolic diseases, such as obesity and type-2 diabetes, are amongst the world's biggest and fasting growing health concerns. Currently, metabolic disease costs more than $2 trillion of global health expenditure and causes 6.5 million deaths globally each year. With the ever-increasing metabolic disease epidemic and the insurmountable costs of treating co-morbidities (cancer, cardiovascular disease and stroke), there has never been a more desperate need to discover novel pharmacological treatments.

The brain plays a critical role in coordinating metabolism; from controlling how much fat we store to how much food we eat. Although the neuronal circuitry underlying metabolic disease is incredibly complex, recent advances in the transgenic tools by which we can manipulate the brain may now make this possible. Using cutting-edge technologies and innovative in vivo models it is our research mission to uncover the brain mechanisms underlying obesity and type 2 diabetes to define novel treatments for metabolic disease.

Staff

Garron Dodd, Head of Laboratory

Collaborators

Professor Tony Tiganis, Head of Metabolism, Diabetes and Obesity Program, Monash Biomedicine Discovery Institute

Professor Jen Bruning, Director, Max Planck Institute for Metabolism Research

Professor Tamas Horvath, Professor of Comparative Medicine and Director of the Neurobiology of Metabolism Program, Yale University

A/Professor Zane Andrews, Deputy Head of Metabolism, Diabetes and Obesity Program, Monash Biomedicine Discovery Institute

Professor Michael Cowley, Head of the Department of Physiology, Monash University

Professor David Spanswick, Monash Biomedicine Discovery Institute

Funding

View Dr Dodd's Research Grants listing here

Research Opportunities

This research project is available to PhD, Masters by Research, Honours, Master of Biomedical Science students to join as part of their thesis.
Please contact the Research Group Leader to discuss your options.

Research Outcomes

Patents:

Dodd GT, Tiganis T. 2017. AUSTRALIA Patent: 2017902239. Methods and compositions for treatment of obesity.

This patent describes several novels pharmacological approaches to specifically target hypothalamic neurons to promote thermogenesis to treat metabolic disease

Research Projects


School Research Themes

Molecular Mechanisms of Disease



Key Contact

For further information about this research, please contact Head of Laboratory Dr Garron Dodd

Department / Centre

Physiology

Unit / Centre

Dodd laboratory: Metabolic Neuroscience

MDHS Research library
Explore by researcher, school, project or topic.