Quorum sensing in malaria parasites
Professor Karen Day
+61 3 8344 7644
Quorum sensing is an altruistic phenomenon in which individual unicellular microorganisms collectively change their behaviour by responding to local population density through the release and receipt of diffusible small molecules known as quorum-sensing molecules. This altruistic phenomenon, to preserve the species rather than the individual, has been studied extensively in prokaryotic systems and recently there are reports in yeasts and protozoa. Quorum-sensing like behaviour by Plasmodium falciparum that regulates population size by programmed cell death is under investigation in our laboratory using biochemical and multi-omics analysis.
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