Paula Miotto

Dr. Miotto has been working in Prof Matthew Watt’s lab since September 2018, shortly after completing her PhD studying the regulation of mitochondrial bioenergetics at the University of Guelph, Canada under the supervision of Dr. Graham Holloway.

Notably, Dr. Miotto was top-ranked within her relative field in two independent national-level post-doctoral fellowship competitions. This includes funding through the Natural Sciences and Engineering Research Council of Canada (NSERC, ranked 1st) and subsequently the Canadian Institutes of Health Research (CIHR, ranked 3rd). Dr. Miotto has also secured ~1.6 million in research funding through the ‘Diabetes Australia Research Program’ (Chief Investigator A; CIA), an ‘MDHS Early Career Researcher grant’ (CIA), a ‘DAP ECR seed grant’ (CIA), an NHMRC Idea’s grant (CIB), and recently an NHMRC Investigator grant (CIA).

Dr. Miotto’s current work mainly focuses on the role of small extracellular vesicles in regulating inter-tissue communication, cell signalling (acute), and metabolic adaptations (chronic) in response to exercise and diseased states. A few of the specialized techniques she uses involve various metabolic functional measurements in vivo, ex vivo, and in cell culture, proteomics/phosphoproteomics, precision cut tissue slicing, and mitochondrial kinetics/reactive oxygen species measurements using high-resolution respirometry (Oroboros; isolated mitochondria and permeabilized tissues).

  • Contact Details
  • Current Research Focus

    Mitochondrial function, skeletal muscle, liver, bone, metabolism/physiology

    Field of ResearchDescription
    601Biochemistry and cell biology
  • Key Skills
    • mitochondrial function
    • metabolism / physiology
    • biochemical adaptations
  • Looking to collaborate?

    Inter-tissue communication in regulating cellular function.