My PhD was carried out under the supervision of Prof. Christian Kurts in Bonn, Germany, and focused on Dendritic Cells in the kidney. I characterized DCs from different compartments of the kidney in the steady state and in different nephritis models and demonstrated the dependence of effector T cell responses on the presence of mature DCs. Subsequently, I joined the lab of Assoc. Prof. Thomas Gebhardt at the University of Melbourne, who is an expert on memory T cells and shares my interest in immune cell functions in peripheral tissues. My research now focuses on T cell immunity in the skin. Using mouse models of skin infection, autoimmunity and melanoma in combination with gene editing techniques such as ectopic expression and CRISPR/Cas9 mediated knockout, I investigate the development and function of Tissue Resident Memory T cells and their role in different skin diseases.
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Current Research Focus
T-cell mediated immune responses in peripheral tissues
Field of Research Description 1107 Immunology 1103 Clinical sciences
- Mouse/rat models
- Flow cytometry
- Gene editing