Annabell Bachem

I am a research fellow in the Department of Microbiology and Immunology at The University of Melbourne investigating the impact of microbiota and their products on effector CD8 T cells. After I studied biology at the Georg-August University (Goettingen, Germany) I undertook my PhD at the Robert Koch institute in Berlin. I was awarded my PhD in cellular immunology at the Humboldt University during which I focused on cross-presenting XCR1-expressing dendritic cells (DC). This work enabled for the first time the identification of these types of DC across different species. I joined the Bedoui group at the Doherty institute to analyse how microbiota and their metabolic products influence the transition of effector to memory CD8 T cells. We are studying the impact onto their phenotype, recall capacity, and metabolism utilizing methods such as cell culture, flow cytometry, a variety of mouse models including germ-free animals, in vivo infection models and qRT-PCR.

  • Contact Details
    Department:Microbiology and Immunology
  • Current Research Focus

    Microbiota and T cells

    Field of ResearchDescription
    6Biological Sciences
    11Medical and Health Sciences
  • Key Skills
    • flow cytometry
    • mouse/rat models
    • cell culture
  • Looking to collaborate?

    I am seeking to collaborate on GPR signalling, HDAC inhibition, and human CD8 T cells in the near future. Additionally I am interested in finding a collaborator with a 'gut model' that relies on CD8 T cells.