Annabell Bachem

I am a Research Officer in the Department of Microbiology and Immunology at The University of Melbourne investigating the impact of microbiota and their products on CD8 T cell immunity. I received my PhD from the Humboldt University/Robert Koch Institute in Berlin/Germany, where I translated the key finding that CD8+ dendritic cells are superior in antigen cross-presentation from mouse to human. This resulted in the first definition of human cross-presenting DC and the ability to define these cells across different species using the now universally used marker XCR1. In 2014 I became a postdoctoral fellow of the German Research Foundation and joined the group of Prof Sammy Bedoui at the Peter Doherty Institute for Infection and Immunity. Over the last six years I have established a research niche in the interphase of immunology, biochemistry and microbiology. My project focusses mainly on the different mechanisms of how the microbiota-derived metabolite butyrate alters T cells in particular their transition from the effector to memory state.

  • Contact Details
    Department:Microbiology and Immunology
  • Current Research Focus

    Microbiota and T cells

    Field of ResearchDescription
    6Biological Sciences
    11Medical and Health Sciences
  • Key Skills
    • flow cytometry
    • mouse/rat models
    • cell culture
  • Looking to collaborate?

    I am seeking to collaborate on GPR signalling, HDAC inhibition, and human CD8 T cells in the near future. Additionally I am interested in finding a collaborator with a 'gut model' that relies on CD8 T cells.