Publications
2023
Afroz, A., Siddiquea, B.N., Shetty, A., Jackson, T.N.W, Watt, A.D. Assessing knowledge and awareness regarding snakebite and management of snakebite envenoming in healthcare workers and the general population: A systematic review and meta-analysis. PLOS Neglected Tropical Diseases (2023)
van Thiel J, Alonso LL, Slagboom J, Dunstan N, Wouters RM, Modahl CM, Vonk FJ, Jackson TNW, Kool J. Highly Evolvable: Investigating Interspecific and Intraspecific Venom Variation in Taipans (Oxyuranus spp.) and Brown Snakes (Pseudonaja spp.). Toxins (2023)
Koludarov, I., Velasque, M., Senoner, T., Jackson, T.N.W., et al. Prevalent bee venom
genes evolved before the aculeate stinger and eusociality. BMC Biol 21 (2023)
Koludarov, I., Senoner, T., Jackson, T.N.W. et al. Domain loss enabled evolution of novel functions in the snake three-finger toxin gene superfamily. Nature Communications (2023)
Schaeffer, R. Pascolutti, V.J., Jackson, T.N.W., Arbuckle, K. Diversity Begets Diversity When Diet Drives Snake Venom Evolution, but Evenness Rather Than Richness Is What Counts. Toxins (2023)
Modahl, C. M., Han, S. X., van Thiel, J., Vaz, C., Dunstan, N. L., Frietze, S., Jackson,
T.N.W., Mackessy, S. P. , Kini, R. M.. Distinct regulatory networks control toxin gene expression in elapid and viperid snakes. bioRxiv (2023)
2022
Suranse, V., Jackson, T.N.W., Sunagar, K. Contextual Constraints: Dynamic Evolution of Snake Venom Phospholipase A2. Toxins (2022)
Tan, C.H., Tan, K.Y., Jackson, T.N.W. Venoms and Toxins: Functional Omics and Pharmacological Insights. Frontiers in Pharmacology (2022)
Driver, C., Jackson, T.N.W., Lagopoulos, J., Hermens, D. Molecular mechanisms underlying the N-methyl-d-aspartate receptor antagonists: Highlighting their potential for transdiagnostic therapeutics. Progress in Neuro-Psychopharmacology and Biological Psychiatry (2022)
Suranse, V., Iyer, A., Jackson, T.N.W., Sunagar, K. Origin and Early Diversification of the Enigmatic Squamate Venom Cocktail in: The Origin and Early Evolutionary History of Snakes (2022; pp.248-268).
Wun MK, Padula AM, Greer RM, Leister EM. A review of 91 canine and feline red-bellied black snake (Pseudechis porphyriacus) envenomation cases and lessons for improved management. Australian Veterinary Journal (2022)
Padula AM. Safety and efficacy of a purified canine immunoglobulin G formulation for treatment of 76 cats clinically affected by the Australian paralysis tick (Ixodes holocyclus). Australian Veterinary Journal (2022)
Wang Y, Watters N, Jones E, Padula A, Leister E, Haworth M, Henning J, Allavena R. Pulmonary Histopathology in Cats and Dogs with Fatal Tick Paralysis. Journal of Comparative Pathology (2022)
2021
Vuong NT, Jackson TNW, Wright CE. Role of Phospholipases A2 in Vascular Relaxation and Sympatholytic Effects of Five Australian Brown Snake, Pseudonaja spp., Venoms in Rat Isolated Tissues. Frontiers in Pharmacology (2021)
Calvete JJ, Lomonte B, Saviola AJ, Bonilla F, Sasa M, Williams DJ, Undheim EAB, Sunagar K, Jackson TNW. Mutual enlightenment: A toolbox of concepts and methods for integrating evolutionary and clinical toxinology via snake venomics and the contextual stance. Toxicon X (2021)
Braitberg G, Nimorakiotakis V, Yap CYL, Mukaro V, Welton R, Parker A, Knott J, Story D. The Snake Study: Survey of National Attitudes and Knowledge in Envenomation. Toxins (Basel) (2021)
Kelly-Bosma M, Leister E, Padula A, Schaffer-White A, Bielefeldt-Ohmann H, Haworth M, Henning J, Allavena R. Pathology of Fatal Australian Black Snake (Pseudechis sp) Envenomation in Two Adult Dogs. Journal of Comparative Pathology (2021)
Grose V, Padula AM, Leister EM. Successful treatment of a potentially fatal eastern brown snake (Pseudonaja textilis) envenomation in a dog with tiger-brown snake antivenom with serial quantification of venom antigen and antivenom concentrations in serum and urine. Australian Veterinary Journal (2021)
2020
Casewell NR, Jackson TNW, Lausten AH, Sunagar K. Causes and consequences of snake venom variation. Trends in Pharmacological Sciences (2020)
Hashmi SU, Alvi A, Munir I, Perveen M, Fazal A, Jackson TNW, Ali SA. Functional venomics of the Big-4 snakes of Pakistan. Toxicon (2020)
Jackson, TNW., and Koludarov, I. How the toxin got its toxicity. Frontiers in Pharmacology (2020)
2019
Jackson TNW, Jouanne H, Vidal N. Snake venom in context: Neglected clades and concepts. Frontiers in Ecology and Evolution (2019)
Harrison RA, Williams, DJ. Outlining progress since the first International Snakebite Awareness Day and some key challenges for next year. Transactions of The Royal Society of Tropical Medicine and Hygiene (2019).
Ruiz de Castañeda R, Grey F, Williams DJ. Citizen science could map snakebite risk. Nature (2019) 571(7766):478.
Zdenek CN, Hay C, Arbuckle K, Jackson TNW, Bos MHA, Op den Brouw B, Debono J, Allen L, Dunstan N, Morley T, Herrera M, Gutiérrez JM, Williams DJ, Fry BG. Coagulotoxic effects by brown snake (Pseudonaja) and taipan (Oxyuranus) venoms, and the efficacy of a new antivenom. Toxicology in Vitro (2019). 58 97-109.
Williams DJ, Faiz MA, Abela-Ridder B, Ainsworth S, Bulfone TC, Nickerson AD, Habib AG, Junghanss T, Fan HW, Turner M, Harrison RA, Warrell DA. Strategy for a globally coordinated response to a priority neglected tropical disease: Snakebite envenoming. PLoS Neglected Tropical Diseases (2019) 13(2): e0007059
2018
Habib, AG, Brown, NI. The Snakebite problem and antivenom crisis from a health-economic perspective. Toxicon (2018) 150, 115-123
Lewin MR, Gutiérrez JM, Samuel SP, Herrera M, Bryan-Quirós W, Lomonte B, Bickler PE, Bulfone TC, Williams DJ. Delayed Oral LY333013 Rescues Mice from Highly Neurotoxic, Lethal Doses of Papuan Taipan (Oxyuranus scutellatus) Venom. Toxins (2018) 10(10)
Longbottom J, Shearer FM, Devine M, Alcoba G, Chappuis F, Weiss DJ, Ray SE, Ray N, Warrell DA, Ruiz de Castañeda R, Williams DJ, Hay SI, Pigott DM. Vulnerability to snakebite envenoming: a global mapping of hotspots. The Lancet (2018; In Press)
Williams DJ, Habib, AG, Warrell DA. Clinical studies of the effectiveness and safety of antivenoms. Toxicon (2018) 150 1-10
Goldenberg, J, Cipriani, V, Jackson, TNW, Arbuckle, K, Debono, J, Dashevsky, D, Panagides N, Ikonomopoulou MP, Koludarov I, Li B, Santana RC, Nouwens A, Jones A, Hay C, Dunstan N, Allen L, Bush B, Miles JJ, Ge L, Kwok HF, Fry BG. Proteomic and functional variation within black snake venoms (Elapidae: Pseudechis). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology (2018) 205, 53-61.
Dobson, J, Yang, DC, op den Brouw, B, Cochran, C, Huynh, T, Kurrupu, S, Sánchez, EE, Massey, DJ, Baumann, K, Jackson, TNW, Nouwens A, Josh P, Neri-Castro E, Alagón A, Hodgson WC, Fry BG. Rattling the border wall: Pathophysiological implications of functional and proteomic venom variation between Mexican and US subspecies of the desert rattlesnake Crotalus scutulatus. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology (2018) 205, 62-69.
2017
Gutiérrez JM, Calvete JJ, Habib AG, Harrison RA, Williams DJ, Warrell DA. Snakebite envenoming. Nature Reviews Disease Primers (2017) 3 17063
Welton RE, Williams DJ, Liew D. Injury trends from envenoming in Australia, 2000-2013. Internal Medicine Journal (2017) 47 (2) 170-176
Panagides, N, Jackson, TNW, Ikonomopoulou, M, Arbuckle, K, Pretzler, R, Yang, D, Ali, S, Koludarov, I, Dobson, J, Sanker, B, Asselin A, Santana RC, Hendrikx I, van der Ploeg H, Tai-A-Pin J, van den Bergh R, Kerkkamp HM, Vonk FJ, Naude A, Strydom MA, Jacobsz L, Dunstan N, Jaeger M, Hodgson WC, Miles J, Fry BG. How the cobra got its flesh-eating venom: Cytotoxicity as a defensive innovation and its co-evolution with hooding, aposematic marking, and spitting. Toxins (2017) 9 103.
Maddock ST, Childerstone A, Fry BG, Williams DJ, Barlow A, Wüster W. Multi-locus phylogeny and species delimitation of Australo-Papuan blacksnakes (Pseudechis Wagler, 1830: Elapidae: Serpentes). Molecular Phylogenetics & Evolution (2017) 107 48 – 55
Pla D, Bande BW, Welton RE, Paiva OK, Sanz L, Segura Á, Wright CE, Calvete JJ, Gutiérrez JM, Williams DJ. Proteomics and antivenomics of Papuan black snake (Pseudechis papuanus) venom with analysis of its toxicological profile and the preclinical efficacy of Australian antivenoms. Journal of Proteomics (2017) 150 201 - 221
Nuebling CM, Williams DJ. Guidelines for the Production, Regulation and Control of Snake Antivenom Immunoglobulins World Health Organization (Expert Committee on Biological Standardization) World Health Organization (2017)
Rathbone J, Franklin R, Gibbs C, Williams DJ. Role of magnesium sulphate in the management of Irukandji syndrome: A systematic review. Emergency Medicine Australasia (2017) 1 9 - 17
Han, H, Baumann, K, Casewell, N, Ali, S, Dobson, J, Koludarov, I, Debono, J, Cutmore, S, Rajapakse, N, Jackson, TNW, Jones R, Hodgson WC, Fry BG, Kuruppu S. The cardiovascular and neurotoxic effects of the venoms of six bony and cartilaginous fish species. Toxins (2017), 9, 67.
Oh H, Shin J, Ato M, Ma X, Williams DJ, Han K, Kim YJ, Kang H, Jung K, Hanada K, Ochiai M, Hung PV, Park S, Ahn C. The First Meeting of the National Control Laboratories for Vaccines and Biologicals in the Western Pacific in 2016. Osong Public Health Research Perspectives (2017) 8 (1) 91 - 103 P02713327
Cipriani V, Debono J, Goldenberg J, Jackson TNW, Arbuckle K, Dobson J, Koludarov I, Li B, Hay C, Dunstan N, Allen L, Hendrikx I, Kwok HF, Fry BG. Correlation between ontogenetic dietary shifts and venom variation in Australian brown snakes (Pseudonaja) Comp. Biochem. Physiol. C: Toxicol. Pharmacol. 2017. 197: 53-60.
Lister C, Arbuckle K, Jackson TNW, Debono J, Zdenek CN, Dashevsky D, Dunstan D, Allen L, Hay C, Bush B, Gillett A, Fry BG. Catch a tiger snake by its tail: Differential toxicity, co-factor dependence and antivenom efficacy in a procoagulant clade of Australian venomous snakes. Comp. Biochem. Physiol. C: Toxicol. Pharmacol. 2017. 202: 39-54.
2016
Ponce, D, Brinkman, DL, Potriquet, J, Mulvenna, J. Tentacle transcriptome and venom proteome of the Pacific sea nettle, Chrysaora fuscescens (Cnidaria: Scyphozoa). Toxins (2016) 8: 120.
Navarro D, Vargas M, Herrera M, Segura Á, Gómez A, Villalta M, Ramírez N, Williams DJ, Gutiérrez JM, León G. Development of a chicken- derived antivenom against the taipan snake (Oxyuranus scutellatus) venom and comparison with an equine antivenom. Toxicon (2016) 120 1 - 8
Herrera M, de Cássia de O Collaço R, Villalta M, Segura Á, Vargas M, Wright CE, Paiva OK, Matainaho T, Jensen SD, León G, Williams DJ, Rodrigues-Simioni L, Gutiérrez JM. Neutralization of the neuromuscular inhibition of venom and taipoxin from the taipan (Oxyuranus scutellatus) by F(ab')2 and whole IgG antivenoms. Toxicology Letters (2016) 241 175 – 183
2015
Ponce, D, Brinkman, DL, Luna-Ramírez, K, Wright, CE, Dorantes-Aranda, JJ Comparative study of the toxic effects of Chrysaora quinquecirrha (Cnidaria: Scyphozoa) and Chironex fleckeri (Cnidaria: Cubozoa) venoms using cell-based assays. Toxicon (2015) 106: 57-67.
Gutiérrez JM, Burnouf T, Harrison RA, Calvete JJ, Brown N, Jensen SD, Warrell DA, Williams DJ, Global Snakebite Initiative. A call for incorporating social research in the global struggle against snakebite. PLOS Neglected Tropical Diseases (2015) 9 9 e0003960
Williams DJ. Snake bite: a global failure to act costs thousands of lives each year. British Medical Journal (2015) 351 h5378
Williams DJ. Snakebite Lessons. MJA InSight (2015) 47(7)
2014
Gutiérrez JM, Burnouf T, Harrison RA, Calvete JJ, Kuch U, Warrell DA, Williams DJ, Global Snakebite Initiative. A multicomponent strategy to improve the availability of antivenom for treating snakebite envenoming. Bull. World Health Organ. (2014) 92 7 526-532
Herrera M, Paiva OK, Pagotto AH, Segura A, Serrano SMT, Vargas M, Villalta M, Jensen SD, León G, Williams DJ, Gutiérrez JM. Antivenomic characterization of two antivenoms against the venom of the taipan, Oxyuranus scutellatus, from Papua New Guinea and Australia. American Journal of Tropical Medicine and Hygiene (2014) 91 5 887-94
Paiva O, Pla D, Wright CE, Beutler M, Sanz L, Gutiérrez JM, Williams DJ, Calvete JJ. Combined venom gland cDNA sequencing and venomics of the New Guinea small-eyed snake, Micropechis ikaheka. Journal of Proteomics (2014) 110 202-29
Aga AM, Hurisa B, Newayeselassie B, Kebede, Kerga S, Kebede A, Godana A, Warrell D, Williams DJ, Taye S, Urga K. Epidemiological survey of snake bite in Ethiopia. Epidemiology (2014) 4 4 174-178
Pla D, Paiva O, Sanz L, Beutler M, Wright CE, Calvete JJ, Williams DJ, Gutiérrez JM. Preclinical efficacy of Australian antivenoms against the venom of the small-eyed snake, Micropechis ikaheka, from Papua New Guinea: an antivenomics and neutralization study. Journal of Proteomics (2014) 110 198-208
Luna-Ramírez K, Bartok A, Restano-Cassulini R, Quintero-Hernández V, Coronas FI, Christensen J, Wright CE, Panyi G, Possani LD. Structure, molecular modeling, and function of the novel potassium channel blocker urotoxin isolated from the venom of the Australian scorpion Urodacus yaschenkoi. Molecular Pharmacology (2014) 86(1) 28-41
Luna-Ramírez K, Sani MA, Silva-Sanchez J, Jiménez-Vargas JM, Reyna-Flores F, Winkel KD, Wright CE, Possani LD, Separovic F. Membrane interactions and biological activity of antimicrobial peptides from Australian scorpion. Biochim Biophys Acta (2014) 1838(9) 2140-8
2013
Warrell DA, Gutiérrez JM, Calvete JJ, Williams DJ. New approaches & technologies of venomics to meet the challenge of human envenoming by snakebites in India. Indian Journal of Medical Research (2013) 138 38-59
Gutiérrez JM, Warrell DA, Williams DJ, Jensen S, Brown N, Calvete JJ, Harrison RA. The need for full integration of snakebite envenoming within a global strategy to combat the neglected tropical diseases: the way forward. PLoS Neglected Tropical Diseases (2013) 7(6) e2162
2012
Herrera M, Fernández J, Vargas M, Villalta M, Segura A, León G, Angulo Y, Paiva O, Matainaho T, Jensen SD, Winkel KD, Calvete JJ, Williams DJ, Gutiérrez JM. Comparative proteomic analysis of the venom of the taipan snake, Oxyuranus scutellatus, from Papua New Guinea and Australia: Role of neurotoxic and procoagulant effects in venom toxicity. Journal of Proteomics (2012) 75 7 2128-2140