Case Studies & Resources

  • Case Studies

    Case Study 1

    Coming soon!

    Case Study 2

    Coming soon!

    Case Study 3

    Coming soon!

  • Publications by MMMPP Researchers

    Dysferlin deficiency alters lipid metabolism and remodels the skeletal muscle lipidome in mice

    Haynes, V. R., Keenan, S. N., Bayliss, J., Lloyd, E. M., Meikle, P. J., Grounds, M. D., and Watt, M. J. 2019. Dysferlin deficiency alters lipid metabolism and remodels the skeletal muscle lipidome in mice. J Lipid Res. 60: 1350-64

  • Websites of interest

    CalR

    A web application for indirect calorimetry analysis

    • CalR generates customisable time, bar and regression plots
    • Useful for analysis of Promethion data sets

    MMPC

    https://www.mmpc.org/

    The National MMPC Educational Portal

    https://www.mmpc.org/shared/rigor.aspx

    A series of webinars to learn the basics of calorimetry and other methods critical for metabolic analysis.

    • Energy expenditure
    • Metabolic homeostasis
    • Glucose  homeostasis
  • Publications of interest

    Progress and challenges in analyzing rodent energy expenditure

    Fernández-Verdejo, R., Ravussin, E., Speakman, J.R., Galgani, J.E. 2019. Progress and challenges in analyzing rodent energy expenditureNature Methods. PMID: 31391589.

    Whole-body energy expenditure is the summed metabolic activities of tissues and, to remove the influence of body size, ratios of energy expenditure to body mass are often applied but can generate spurious differences. In 2011, a group of experts proposed adoption of ANCOVA for the analysis of metabolic rate but, seven years later, analyses based on ratios remain the most frequent. We discuss some of the barriers to adopting better analytical procedures.