Cristiana Mattei

Key areas of interest: Stem Cells and Disease Modelling, Organoids, Brain Development


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The major aim of my PhD studies is to model human neurogenesis in physiological and pathological conditions by developing a suitable in vitro 3D culture system using human pluripotent stem cells. Modelling human neurogenesis in vitro would represent a unique tool to elucidate many aspects of those mechanisms that lead to the high complexity of the human brain and to neurological disorders. Additionally such a model will provide a platform to test new drugs as well as a cell source for regenerative medicine therapy.