This theme addresses fundamental biological questions regarding cell identity, cell state and cell fate. Understanding cell differentiation and regulation underpins all stem cell research and applications.
Research focus: exploring expression and function of genes involved in neuropsychiatric disorders and applications of long-read Nanopore sequencing.
Research focus: analysing genes that regulate stem cell maintenance and differentiation using genetic screening in Drosophila and conditional mouse knockout models.
Research focus: investigation of factors directing enteric neuron subtype differentiation and their maintenance
Research focus: determining how the pelvic nervous system develops, how it controls complex bodily functions and how it might be manipulated to provide clinical treatments.
Research focus: exploring mechanisms of gene regulation that drive sex determination and gonad development as well as understanding the underlying causes of sex development disorders in humans.
Research focus: exploring the ways in which natural selection and evolutionary change have shaped the human species, with a particular focus on gene regulatory processes.
Research focus: examining the development of the urogenital system in mammals and working on establishing stem cells from native Australian mammals.
Research focus: generating of reporter lines to facilitate directed differentiation of kidney cells from human pluripotent stem cells.
Research focus: using human pluripotent stem cells to understand diseases of the blood, endocrine and immune systems.
Research focus: using human pluripotent stem cells to understand the development of blood cells, endothelium and diseases of the blood system.
Research focus: analysing the molecular mechanisms behind epigenetic silencing.
Research focus: identifying the genes that direct the behaviour of stem cells and differentiated cells in the developing nervous system.
Research focus: Regenerative Dentistry, specifically the potential therapeutic manipulation of the dental pulp stem cells.