Pharmacology and Therapeutics Research

Learn about this department's research groups and the projects they are working on.

ARC Centre for Personalised Therapeutics Technologies

"Clock-off time" for inflammation and remodelling in chronic inflammatory diseases: casein kinase inhibitors

Development and application of soft culturing microenvironment for novel drug discovery

Glucocorticoid responsiveness in the lung: impact of inflammation and infection

Australian Venom Research Unit

Australian bite and sting trends: Australian Venomous Injury Project (AVIP)

The Treatment of Papuan Taipan Envenoming in Papua New Guinea

Cappai laboratory: Neurodegeneration and Brain Injury

Crack laboratory: Neuropharmacology

Innate immunity and neural injury

Oxidative stress and neural injury

Traumatic brain injury

Crouch laboratory: Neurodegenerative disease

Hoyer laboratory: Translational neuroscience

PROFESSOR DANIEL HOYER - HEAD OF DEPARTMENT

Hughes & Northfield laboratory: Drug design

Growth factors and peptide mimetics

Relaxin family peptide hormones

Lew laboratory: Theoretical and empirical pharmacology

Lung Health Research Centre

Lung Disease Research Laboratory

Nanoparticle Modulation of Mast Cell Function

Novel Mast Cell-Derived Mediators

Pathogenesis of chronic lung disease

Regulation of Mast Cell Activation

Mangum Lab: Translational Proteomics

Clinical Proteomics

Molecular mechanisms of drug resistance in cancer

Prognostic biomarker and therapeutic target discovery in stroke

Saunders laboratory: Developmental neuroscience and neurotrauma

Schneider-Futschik laboratory: Cystic Fibrosis pharmacology

Stewart Laboratory: Mechanopharmacology

Affiliated with the Lung Health Research Centre (LHRC)

Velkov laboratory: Antiinfective pharmacology

Design and development of antibiotics against multidrug resistant bacteria

Design of inhibitory drugs for molecular components of the siderophore biosynthetic pathway that are crucial for iron sequestration during mycobacterium tuberculosis (TB) pathogenesis

Plasma protein binding of antibiotics

Wright laboratory: Cardiovascular Therapeutics Unit

Effects of hypertension on renal and hindquarter vascular reactivity in vivo and in vitro

Endothelin pharmacology in the setting of pulmonary hypertension

Manipulating the endocannabinoid system to alter cardiovascular function in hypertension

Novel technique to determine the pKA of clonidine at prejunctional α2-adrenoceptors in sympathetic transmission

Preclinical pharmacology – cardiovascular efficacy and safety R&D

Reassessment of α1-adrenoceptor mechanism in artery contraction: role of ATP and pannexin channels

Student projects

The cardiovascular pharmacology of snake venoms from Papua New Guinea and Australia

The link between cardiovascular disease and neurodegeneration – focus on Alzheimer’s disease

Trovafloxacin – an antibiotic with additional properties