Mechanisms underlying early generation of human T cell memory
| Lead Researcher | Number | Webpage | |
|---|---|---|---|
| Associate Professor Katherine Kedzierska | kkedz@unimelb.edu.au | +61 3 8344 3384 | View page |
Project Details
Though immunological memory is of pivotal importance for vaccine development and immunotherapy, the molecular and differentiation pathways central to the generation of (particularly) human CD8+ T-cell memory are poorly understood. Here, we aim to:
- establish the key factors driving the early establishment of influenza-specific T cell memory;
- To define molecular processes involved in CD27-mediated co-stimulation of human T cells. As memory is crucial for protection against recurrent infections, this work will provide novel insights into the generation and efficacy of human T cell memory populations and inform effective CD27-mediated stimulation for immunotherapy.
Research Group
Kedzierska laboratory: Immunity to pandemic and newly emerged influenza viruses
Faculty Research Themes
School Research Themes
Infection & Immunity, Molecular Mechanisms of Disease
Key Contact
For further information about this research, please contact the research group leader.
Department / Centre
Unit / Centre
Kedzierska laboratory: Immunity to pandemic and newly emerged influenza viruses
MDHS Research library
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