Innovative approaches to prepare synthetic, partially synthetic and natural product-based vaccines
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We have developed a modular approach to vaccine manufacture that involves the selective chemical ligation of individually assembled segments of a vaccine candidate. This modular approach offers a "plug and play" approach to vaccine development hastening the speed of new vaccine development and production. The major advantage of utilising this technology is that it provides the ability to incorporate conformational determinants such as those required for generation of effective antibody responses. This approach has the potential to make use of new chemistries and lends itself to the development of totally synthetic and partially synthetic vaccines as well as vaccines that are based on completely natural products.
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