Dendritic cell maturation following different microbial stimulation
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The aim of my project is to understand the mechanisms of DC maturation following activation with different microbial stimuli and the differential requirements for CD4+ T cell help in the process of DC priming. More precisely, I am interested in elucidating how the combination and integration of these differential signals shapes the secretion of cytokines by DC necessary to induce an efficient CTL response upon infection.
NB: this is a collaborative project with the Bedoui group.
Dr Sammy Bedoui
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