A gut feeling about new therapies for glioma

Project Details

Gliomas are a very aggressive form of brain cancer, with a very poor 5-year survival rate. Gliomas can arise from over-proliferation of glial cells or stem cells in the brain. Glial cells are a prominent part of the enteric nervous system in the gut.

In this project, we will use a novel line of transgenic mice to investigate gene expression patterns between glial cells in the brain and the gut using RNA-sequencing technology and bioinformatic analysis.

Researchers

Dr Lincon Stamp, ARC DECRA Fellow

Dr Marlene Hao, ARC DECRA Fellow

Ms Annette Bergner, Senior Research Assistant

Yvette Wilson, Research Assistant

Collaborators

Dr Theo Mantamadiotis, University of Melbourne

Research Opportunities

This research project is available to PhD, Masters by Research, Honours, Master of Biomedical Science, Post Doctor Research students to join as part of their thesis.
Please contact the Research Group Leader to discuss your options.

Research Outcomes

Hao MM, Foong JP, Bornstein JC, Li ZL, Vanden Berghe P, Boesmans W. Enteric nervous system assembly: Functional integration within the developing gut. Dev Biol. 2016; 417:168-81.

Hao MM, Young HM. Development of enteric neuron diversity. J Cell Mol Med. 2009; 13:1193-210.

Research Group

Stamp & Hao laboratory: Development of the enteric nervous system



Faculty Research Themes

Neuroscience

School Research Themes

Biomedical Neuroscience, Stem Cells



Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

Anatomy and Neuroscience

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