Stamp & Hao laboratory: Development of the enteric nervous system

Research Overview

View Dr Stamp's latest publications listing here and Find an Expert profile here

View Dr Hao's latest publications listing here and Find an Expert profile here

Proper development and function of the digestive tract is crucial for good health. Gastrointestinal function relies on the co-ordinated activity of neural circuits in the enteric nervous system, a network of neurons and glia located within the wall of the gut. During development, enteric neurons arise from neural crest cells that emigrate from the caudal hindbrain and migrate into and along the developing gut. Enteric neural crest cells are thought to migrate further than any other embryonic cell population.

Our research is focused on the mechanisms controlling the development of the enteric nervous system and the potential of cell therapy for treating diseases of the enteric nervous system.

Staff

Dr Lincon Stamp, ARC DECRA Fellow

Dr Marlene Hao, ARC DECRA Fellow

Ms Annette Bergner, Senior Research Assistant

Yvette Wilson, Research Assistant

Collaborators

Associate Professor Sebastian King, Royal Children’s Hospital, Melbourne

Professor Pieter Vanden Berghe, KU Leuven, Belgium

Professor Hans Clevers, Utrecht University, Netherlands

Professor Christine Wells, University of Melbourne

Professor John Furness, University of Melbourne

Professor Joel Bornstein, University of Melbourne

Dr Jaime Foong, University of Melbourne

Dr Theo Mantamadiotis, University of Melbourne

Associate Professor Helen Abud, Monash University

Professor Don Newgreen, Murdoch Childrens' Research Institute

Professor Andrew Allen, University of Melbourne Associate

Professor Kate Drummond, Royal Melbourne Hospital

Funding

2019-2022 ARC Discovery Early Career Research AwardGenes underlying enteric neuron subtype differentiation
2018-2020 ARC Discovery Early Career Research Award. Understanding interactions between gut epithelial stem cells and neurons
2015-2017 (extended until 31.12.18) NHMRC Project Grant. Cell therapies for enteric neuropathies - the essential next step
2014-2019 NHMRC Early Career CJ Martin FellowshipCircuit development in the Enteric Nervous System
2018 CASS Foundation Med/Sci Grant. A gut feeling about therapies for glioma treatment

Research Opportunities

This research project is available to PhD, Masters by Research, Honours, Master of Biomedical Science, Post Doctor Research students to join as part of their thesis.
Please contact the Research Group Leader to discuss your options.

Research Projects



Faculty Research Themes

Neuroscience

School Research Themes

Biomedical Neuroscience, Stem Cells



Key Contact

For further information about this research, please contact Joint Heads of Laboratory Dr Lincon Stamp & Dr Marlene Hao

Department / Centre

Anatomy and Neuroscience

Unit / Centre

Stamp & Hao laboratory: Development of the enteric nervous system

MDHS Research library
Explore by researcher, school, project or topic.