Nick Scott


My research focuses on the identification and characterisation of microbial enzymes which chemically link carbohydrates to proteins. Through the addition of carbohydrates to proteins, a process known as protein glycosylation, microbes are able to radically alter the function of proteins. Within a range of infections such as Malaria, Gonorrhoea and Salmonella, microbial protein glycosylation is used for both defensive and offensive processes; enabling pathogens to fortify themselves against the host immune response or to disarm the host’s ability to resist infection. By better understanding these systems, the goal of my research aims to develop approaches to target these enzymes for antimicrobial strategies. To achieve this, my work focuses on developing new methodologies to monitor glycosylation, characterising the proteins which are modified by these enzymes and understanding the role of microbial glycosylation systems during pathogenesis.

  • Contact Details
    Department:Department of Microbiology and Immunology
    Email: nichollas.scott@unimelb.edu.au
    Phone:0416 020 493
  • Current Research Focus

    Glycosylation, mass spectrometry, proteomics, pathogens, microbes

    Field of ResearchDescription
    605Microbiology
    601Biochemistry and Cell Biology
  • Key Skills
    • Mass Spectrometry
    • Proteomics
  • Looking to collaborate?

    Looking for collaborators with interesting and tractable biological systems.