Kai Kysenius


I am a Finnish neuroscientist with an international background and a keen interest in researching novel approaches to understand and treat neurodegenerative diseases. After completing my PhD (in Physiology and Neuroscience) in 2015 at the Neuroscience Center at the University of Helsinki, I was awarded the Sigrid Juselius Postdoctoral Fellowship to relocate to Melbourne to study the role of metal homeostasis in neurodegenerative disorders. My PhD work focused on elucidating the role of lipoprotein receptor modulation on neuronal survival in the context of Alzheimer's disease. My current work heavily utilises advanced mass spectrometry elemental imaging (laser ablation-inductively coupled plasma-mass spectrometry; LA-ICP-MS) to study human samples, bio fluids and animal tissues in studies relating to: motor neurone disease (MND), multiple sclerosis, AD/PD/HD, colorectal cancer, breast cancer, muscle dystrophies, psychotropic drug pharmacokinetics and novel amyloid binding compounds. I was awarded an ECR research grant for 2019 to study gender bias in MND, work which is currently ongoing. Although my work has recently broadened to a number of subject areas through collaborations, my passion lies in neuroscience and the less-mainstream topics such as metal, hormone and lipid biology.

  • Contact Details
  • Current Research Focus

    Elemental signatures of disease

    Field of ResearchDescription
    30101Analytical Spectrometry
    110903Central Nervous System
  • Key Skills
    • Neuroscience
    • Mouse/rat models
    • Elemental/laser ablation mass spectrometry imaging
    • Molecular biology
  • Looking to collaborate?

    Basic metal/element biology and novel ionophore/metal based drugs/sensors in neuroscience or related fields