David Ascher

David Ascher is Head of the Structural Biology and Bioinformatics Laboratory in the Department of Biochemistry, University of Melbourne. He is a Director of the Australian Society for Medical Research, an Associate Editor of PBMB and holds honorary positions at Cambridge University, FIOCRUZ, and the Tuscany University Network. His research focuses on unravelling the link between genotype and phenotype, using computational and experimental approaches to understand the effects of mutations on protein structure and function. They have developed a platform of 18 widely used programs for assessing the molecular consequences of coding variants (>350,000 hits per month). Working with clinical collaborators in Australia, Brazil and UK, these methods have been translated to guide diagnosis, management and treatment of a number of hereditary diseases, rare cancers and drug resistant infections.

  • Contact Details
    Department:Department of Biochemistry and Molecular Biology
    Email: david.ascher@unimelb.edu.au
    Phone:03 9035 4794
  • Current Research Focus

    Computational biology and bioinformatics

    Field of ResearchDescription
    60112Structural Biology (incl. Macromolecular Modelling)
  • Key Skills
    • Bioinformatics
    • Structural biology
    • Molecular modelling
    • Machine learning
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