Miegunyah Fellowship Public Lecture: From AIDS to Zika – what's next?

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Miegunyah Fellowship Public Lecture by Professor David O'Connor (University of Wisconsin-Madison)

From AIDS to Zika – what's next?

Thirty-five years after its discovery, HIV is the world's most intensively studied virus. This research has lead to extraordinary breakthroughs including safe combinations of effective drugs and the identification of multiple strategies to protect people from becoming infected. Knowledge gained from studying HIV has had a halo effect on all infectious disease research, as tools developed initially to combat HIV are applied to other pathogens.

Yet the sudden emergence of H1N1 influenza in 2009, West African Ebola in 2014 and Zika virus in 2015 demonstrate that we remain underprepared for scientific, social, and political consequences of new virus outbreaks – and such outbreaks will happen again in the future.

In this lecture, Professor O'Connor will show

  • how a global scientific research community, that included significant partnerships between wealthy and resource limited countries, improved the public health response to HIV, and
  • how these same partnerships have catalysed research into other new viruses.

Strengthening these collaborations is essential to maximise infectious disease preparedness in an interconnected world.

Professor O'Connor will discuss his own experience discovering and characterising novel viruses to illustrate how obscure viruses circulating in wild African primates today, share biological features with HIV, and whether we should worry that these viruses may pose a major risk to human health later in the 21st century.

Professor David O'Connor

Professor David O'Connor is a UW Medical Foundation Professor of Pathology and Laboratory Medicine at the University of Wisconsin-Madison. His laboratory studies the interplay of viruses, immune responses, and host genetics. His research group studies HIV, Zika virus, and emerging, understudied viruses that might threaten human health in the future, as well as the genetic attributes that make some individuals unusually susceptible or resistant to infectious diseases. Among these viruses, he is particularly interested in simian arteriviruses, a group of viruses that infect African nonhuman primates and share worrisome features with the simian immunodeficiency viruses that gave rise to HIV.

The Miegunyah Distinguished Visiting Fellowship

The Miegunyah Distinguished Visiting Fellowship Program was established in 1993 by the University of Melbourne to enable distinguished academics from international institutions the opportunity to visit the University of Melbourne and share their work. The program is generously funded by the Russel and Mab Grimwade Miegunyah Fund.

Professor O'Connor is a Miegunyah Distinguished Visiting Fellow on a yearlong sabbatical at the University of Melbourne with his wife, Professor Shelby O'Connor, and his 10-year old son, Eli O'Connor.