Publications

2018

Habib, AG, Brown, NI. The Snakebite problem and antivenom crisis from a health-economic perspective. Toxicon (2018) 150, 115-123

Lewin MR, Gutiérrez JM, Samuel SP, Herrera M, Bryan-Quirós W, Lomonte B, Bickler PE, Bulfone TC, Williams DJ. Delayed Oral LY333013 Rescues Mice from Highly Neurotoxic, Lethal Doses of Papuan Taipan (Oxyuranus scutellatus) Venom. Toxins (2018) 10(10)

Longbottom J, Shearer FM, Devine M, Alcoba G, Chappuis F, Weiss DJ, Ray SE, Ray N, Warrell DA, Ruiz de Castañeda R, Williams DJ, Hay SI, Pigott DM. Vulnerability to snakebite envenoming: a global mapping of hotspots. The Lancet (2018; In Press)

Williams DJ, Habib, AG, Warrell DA. Clinical studies of the effectiveness and safety of antivenoms. Toxicon (2018) 150 1-10

Goldenberg, J, Cipriani, V, Jackson, TNW, Arbuckle, K, Debono, J, Dashevsky, D, Panagides N, Ikonomopoulou MP, Koludarov I, Li B, Santana RC, Nouwens A, Jones A, Hay C, Dunstan N, Allen L, Bush B, Miles JJ, Ge L, Kwok HF, Fry BG. Proteomic and functional variation within black snake venoms (Elapidae: Pseudechis). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology (2018) 205, 53-61.

Dobson, J, Yang, DC, op den Brouw, B, Cochran, C, Huynh, T, Kurrupu, S, Sánchez, EE, Massey, DJ, Baumann, K, Jackson, TNW, Nouwens A, Josh P, Neri-Castro E, Alagón A, Hodgson WC, Fry BG. Rattling the border wall: Pathophysiological implications of functional and proteomic venom variation between Mexican and US subspecies of the desert rattlesnake Crotalus scutulatus. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology (2018) 205, 62-69.

2017

Gutiérrez JM, Calvete JJ, Habib AG, Harrison RA, Williams DJ, Warrell DA. Snakebite envenoming. Nature Reviews Disease Primers (2017) 3 17063

Welton RE, Williams DJ, Liew D. Injury trends from envenoming in Australia, 2000-2013. Internal Medicine Journal (2017) 47 (2) 170-176

Panagides, N, Jackson, TNW, Ikonomopoulou, M, Arbuckle, K, Pretzler, R, Yang, D, Ali, S, Koludarov, I, Dobson, J, Sanker, B, Asselin A, Santana RC, Hendrikx I, van der Ploeg H, Tai-A-Pin J, van den Bergh R, Kerkkamp HM, Vonk FJ, Naude A, Strydom MA, Jacobsz L, Dunstan N, Jaeger M, Hodgson WC, Miles J, Fry BG. How the cobra got its flesh-eating venom: Cytotoxicity as a defensive innovation and its co-evolution with hooding, aposematic marking, and spitting. Toxins (2017) 9 103.

Maddock ST, Childerstone A, Fry BG, Williams DJ, Barlow A, Wüster W. Multi-locus phylogeny and species delimitation of Australo-Papuan blacksnakes (Pseudechis Wagler, 1830: Elapidae: Serpentes). Molecular Phylogenetics & Evolution (2017) 107 48 – 55

Pla D, Bande BW, Welton RE, Paiva OK, Sanz L, Segura Á, Wright CE, Calvete JJ, Gutiérrez JM, Williams DJ. Proteomics and antivenomics of Papuan black snake (Pseudechis papuanus) venom with analysis of its toxicological profile and the preclinical efficacy of Australian antivenoms. Journal of Proteomics (2017) 150 201 - 221

Nuebling CM, Williams DJ. Guidelines for the Production, Regulation and Control of Snake Antivenom Immunoglobulins World Health Organization (Expert Committee on Biological Standardization) World Health Organization (2017)

Rathbone J, Franklin R, Gibbs C, Williams DJ. Role of magnesium sulphate in the management of Irukandji syndrome: A systematic review. Emergency Medicine Australasia (2017) 1 9 - 17

Han, H, Baumann, K, Casewell, N, Ali, S, Dobson, J, Koludarov, I, Debono, J, Cutmore, S, Rajapakse, N, Jackson, TNW, Jones R, Hodgson WC, Fry BG, Kuruppu S. The cardiovascular and neurotoxic effects of the venoms of six bony and cartilaginous fish species. Toxins (2017), 9, 67.

Oh H, Shin J, Ato M, Ma X, Williams DJ, Han K, Kim YJ, Kang H, Jung K, Hanada K, Ochiai M, Hung PV, Park S, Ahn C. The First Meeting of the National Control Laboratories for Vaccines and Biologicals in the Western Pacific in 2016. Osong Public Health Research Perspectives (2017) 8 (1) 91 - 103 P02713327

Cipriani V, Debono J, Goldenberg J, Jackson TNW, Arbuckle K, Dobson J, Koludarov I, Li B, Hay C, Dunstan N, Allen L, Hendrikx I, Kwok HF, Fry BG. Correlation between ontogenetic dietary shifts and venom variation in Australian brown snakes (Pseudonaja) Comp. Biochem. Physiol. C: Toxicol. Pharmacol. 2017. 197: 53-60.

Lister C, Arbuckle K, Jackson TNW, Debono J, Zdenek CN, Dashevsky D, Dunstan D, Allen L, Hay C, Bush B, Gillett A, Fry BG. Catch a tiger snake by its tail: Differential toxicity, co-factor dependence and antivenom efficacy in a procoagulant clade of Australian venomous snakes. Comp. Biochem. Physiol. C: Toxicol. Pharmacol. 2017. 202: 39-54.

2016

Navarro D, Vargas M, Herrera M, Segura Á, Gómez A, Villalta M, Ramírez N, Williams DJ, Gutiérrez JM, León G. Development of a chicken- derived antivenom against the taipan snake (Oxyuranus scutellatus) venom and comparison with an equine antivenom. Toxicon (2016) 120 1 - 8

Herrera M, de Cássia de O Collaço R, Villalta M, Segura Á, Vargas M, Wright CE, Paiva OK, Matainaho T, Jensen SD, León G, Williams DJ, Rodrigues-Simioni L, Gutiérrez JM. Neutralization of the neuromuscular inhibition of venom and taipoxin from the taipan (Oxyuranus scutellatus) by F(ab')2 and whole IgG antivenoms. Toxicology Letters (2016) 241 175 – 183

2015

Gutiérrez JM, Burnouf T, Harrison RA, Calvete JJ, Brown N, Jensen SD, Warrell DA, Williams DJ, Global Snakebite Initiative. A call for incorporating social research in the global struggle against snakebite. PLOS Neglected Tropical Diseases (2015) 9 9 e0003960

Williams DJ. Snake bite: a global failure to act costs thousands of lives each year. British Medical Journal (2015) 351 h5378

Williams DJ. Snakebite Lessons. MJA InSight (2015) 47(7)

2014

Gutiérrez JM, Burnouf T, Harrison RA, Calvete JJ, Kuch U, Warrell DA, Williams DJ, Global Snakebite Initiative. A multicomponent strategy to improve the availability of antivenom for treating snakebite envenoming. Bull. World Health Organ. (2014) 92 7 526-532

Herrera M, Paiva OK, Pagotto AH, Segura A, Serrano SMT, Vargas M, Villalta M, Jensen SD, León G, Williams DJ, Gutiérrez JM. Antivenomic characterization of two antivenoms against the venom of the taipan, Oxyuranus scutellatus, from Papua New Guinea and Australia. American Journal of Tropical Medicine and Hygiene (2014) 91 5 887-94

Paiva O, Pla D, Wright CE, Beutler M, Sanz L, Gutiérrez JM, Williams DJ, Calvete JJ. Combined venom gland cDNA sequencing and venomics of the New Guinea small-eyed snake, Micropechis ikaheka. Journal of Proteomics (2014) 110 202-29

Aga AM, Hurisa B, Newayeselassie B, Kebede, Kerga S, Kebede A, Godana A, Warrell D, Williams DJ, Taye S, Urga K. Epidemiological survey of snake bite in Ethiopia. Epidemiology (2014) 4 4 174-178

Pla D, Paiva O, Sanz L, Beutler M, Wright CE, Calvete JJ, Williams DJ, Gutiérrez JM. Preclinical efficacy of Australian antivenoms against the venom of the small-eyed snake, Micropechis ikaheka, from Papua New Guinea: an antivenomics and neutralization study. Journal of Proteomics (2014) 110 198-208

2013

Warrell DA, Gutiérrez JM, Calvete JJ, Williams DJ. New approaches & technologies of venomics to meet the challenge of human envenoming by snakebites in India. Indian Journal of Medical Research (2013) 138 38-59

Gutiérrez JM, Warrell DA, Williams DJ, Jensen S, Brown N, Calvete JJ, Harrison RA. The need for full integration of snakebite envenoming within a global strategy to combat the neglected tropical diseases: the way forward. PLoS Neglected Tropical Diseases (2013) 7(6) e2162

2012

Herrera M, Fernández J, Vargas M, Villalta M, Segura A, León G, Angulo Y, Paiva O, Matainaho T, Jensen SD, Winkel KD, Calvete JJ, Williams DJ, Gutiérrez JM. Comparative proteomic analysis of the venom of the taipan snake, Oxyuranus scutellatus, from Papua New Guinea and Australia: Role of neurotoxic and procoagulant effects in venom toxicity. Journal of Proteomics (2012) 75 7 2128-2140