Seminar (cancelled): Building vessels on a chip to model genetic vascular diseases using patient-specific iPSCs

** This seminar has been cancelled **

The seminar is presented by Dr Valeria Orlova and hosted by the Centre for Stem Cell Systems.

Valeria Orlova PhD | Assistant Professor, Leiden University Medical Center

Valeria Orlova, PhD is an Assistant Professor at the Department of Anatomy and Embryology, Leiden University Medical Center (LUMC), Leiden, The Netherlands.

She obtained a Möller Foundation Research grant (750K Euro, 2014) to establish a new vascular research group in the Department of Anatomy and Embryology at LUMC (chaired by Prof. Mummery). At the LUMC, Dr. Orlova developed efficient protocols for the derivation of endothelial cells from hPSCs.

She is a co-inventor on the patent on the differentiation of endothelial cells from hPSCs, which is licensed by a biotech spin-out from the LUMC, Ncardia (formerly Pluriomics). She is a part of the Netherlands Organ on a Chip Initiative (NOCI) coordinated by Prof. Mummery and European Organ on Chip (EUROoC) training network.

Dr. Orlova’s current research is focused on the application of human pluripotent stem cell (hPSC) technology to the cardiovascular biology, such as differentiation of cardiovascular cell types, including tissue-specific endothelial cells and macrophages, as well as the development of realistic disease models for drug repurposing from hPSCs.