DC targetting vaccines
Generating robust immune responses requires delivering vaccines to Dendritic cells to initiate immune responses. We are collaborating with Drs Mireille Lahoud, Irene Caminschi, Andrew Lew, and Ken Shortman from WEHI and the Burnet who have developed clever antibodies that target a molecule on DCs called Clec9A. These antibodies can be linked to vaccine antigens to promote high level immunity. This has worked very well in mice and we are now further developing this concept.
Dr Stephen Kent, Dr Rob De Rose, Sheilajen Alcantara
WEHI Catalyst award
Faculty Research Themes
School Research Themes
For further information about this research, please contact the research group leader.