DC targetting vaccines

Project Details

Generating robust immune responses requires delivering vaccines to Dendritic cells to initiate immune responses. We are collaborating with Drs Mireille Lahoud, Irene Caminschi, Andrew Lew, and Ken Shortman from WEHI and the Burnet who have developed clever antibodies that target a molecule on DCs called Clec9A. These antibodies can be linked to vaccine antigens to promote high level immunity. This has worked very well in mice and we are now further developing this concept.

Researchers

Dr Stephen Kent, Dr Rob De Rose, Sheilajen Alcantara

Funding

WEHI Catalyst award

Research Group

Kent laboratory: HIV vaccines; immune responses to HIV-1; immunotherapy



Faculty Research Themes

Infection and Immunology

School Research Themes

Infection & Immunity, Molecular Mechanisms of Disease



Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

Microbiology and Immunology