How does regulation of nuclear importation affect stem cell maintenance

Project Details

We have identified a nuclear importation factor that is required for maintenance of the germline stem cell population. We will use immonostaining and confocal microscopy to determine the effects of mutations of this factor on stem cell maintenance and conduct genetic interactions to identify proteins that are imported by this factor into the stem cell nucleus.

Researchers

Associate Professor Gary Hime

Collaborators

Professor K. Loveland, Monash University

Research Group

Hime laboratory: Stem cell genetics



Faculty Research Themes

Cancer

School Research Themes

Cancer in Biomedicine, Molecular Mechanisms of Disease



Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

Anatomy and Neuroscience

Unit / Centre

Hime laboratory: Stem cell genetics