Analysing genetic roles of translational repressors in Drosophila stem cells
We have identified three RNA-binding proteins, Musashi, Real Musashi and Held-Out-Wings (HOW) that are required to either prevent stem cells from differentiating in the stem cell niche or are required to regulate the cell cycle of stem cells. This project utilises a variety of genetic, molecular biology and immunostaining techniques to identify the roles of these proteins in different stem cell populations.
Associate Professor Gary Hime
Dr. Nicole Siddall