Analysing genetic roles of translational repressors in Drosophila stem cells

Project Details

We have identified three RNA-binding proteins, Musashi, Real Musashi and Held-Out-Wings (HOW) that are required to either prevent stem cells from differentiating in the stem cell niche or are required to regulate the cell cycle of stem cells. This project utilises a variety of genetic, molecular biology and immunostaining techniques to identify the roles of these proteins in different stem cell populations.

Researchers

Associate Professor Gary Hime

Collaborators

Dr. Nicole Siddall

Research Group

Hime laboratory: Stem cell genetics



Faculty Research Themes

Cancer

School Research Themes

Cancer, Molecular Mechanisms of Disease



Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

Anatomy and Neuroscience